When people think about startups working with the government, the phrase ?black box? often comes up. But what if that box is finally being pried open?

In this episode?recorded live at the American Dynamism Summit in DC?we talk with two Chief Technology Officers at the heart of American defense: Alex Miller, CTO for the Chief of Staff of the Army, and Justin Fanelli, CTO at the Department of the Navy. Along with a16z partner Leila Hay, they break down how the Department of Defense is shifting from decades-old processes to software-speed execution, why the real bottlenecks are cultural, not technical, and how startups can actually navigate and scale within this massive system.

From replacing outdated procurement with faster pathways, to getting tech into the hands of warfighters faster, this is a rare look inside the government?s most ambitious efforts to modernize?and what it means for builders on the outside.

Is it time to rip up the system and start fresh? Or are the seeds of change already in the ground?

Resources: 

DoD Contracts for Startups 101: https://a16z.com/dod-contracting-for-startups-101/

Find Justin on LinkedIn: https://www.linkedin.com/in/justinfanelli/

Find Leila on LinkedIn: https://www.linkedin.com/in/leilahay/

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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

This month, a16z?s Consumer team released the fourth edition of the GenAI 100 ? a data-driven ranking of the top 50 AI-first web products and mobile apps, based on unique monthly visits and active users.

In just six months, the consumer AI landscape has shifted dramatically. Some products surged ahead, others plateaued, and a few unexpected players reshaped the leaderboard entirely.

In this episode, a16z General Partner Anish Acharya and Partner Olivia Moore join us to unpack the latest rankings and explore the key cultural and product moments that brought us to this point.

Which applications are leading the pack ? and which ones are quietly on the rise? What do trends like AI video, companion apps, and ?vibe coding? reveal about the future of consumer AI? And for the first time, the team also analyzed which products aren?t just gaining users, but generating real revenue.

If you?re looking to understand where we are in the GenAI adoption cycle ? and what might come next ? this episode offers a data-backed view into one of the fastest-moving corners of technology.

You can find the full GenAI 100 list at a16z.com/genai100-4

 

Timecodes: 

00:00: Consumer AI Trends

00:36: The Gen AI 100 List: Methodology and Insights

02:38: Pivotal Moments in AI Development

05:37: Assumptions and Realities in AI

08:49: Emerging Trends and Newcomers

11:53: The Brink List: Near Misses and Future Contenders

16:13: Surprises and Consistencies in AI Adoption

18:31: The Future of AI Applications

19:54: Traffic Trends and User Demographics

20:32: Resurgence and New Use Cases

22:47: Competitors and Market Dynamics

25:30: AI Video Models and Trends

29:23: Mobile vs Desktop Usage

30:34: Revenue Insights and Monetization

34:06: Key Learnings and Final Thoughts

 

Resources: 
Find Anish on X: https://x.com/illscience

Find Olivia on X: https://x.com/omooretweets

 

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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

The global race for AI leadership is no longer just about companies?it?s about nations. AI isn?t just computing infrastructure; it?s cultural infrastructure, economic strategy, and national security all rolled into one.

In this episode, Jensen Huang, founder and CEO of NVIDIA, and Arthur Mensch, cofounder and CEO of Mistral, sit down to discuss sovereign AI, national AI strategies, and why every country must take ownership of its digital intelligence.

How AI will reshape global economies and GDPThe full AI stack?from chips to models to AI factoriesWhy AI is both a general purpose technology and deeply specializedThe open-source vs. closed AI debate and its impact on sovereigntyWhy no one will build AI for you?you have to do it yourself

Is this the most consequential technology shift of all time? If so, the stakes have never been higher.

Resources: 

Find Arthur on X: https://x.com/arthurmensch

Find Anjney on X: https://www.linkedin.com/in/anjney/

Find NVIDIA on X: https://x.com/nvidia

Find Mistral: https://x.com/MistralAI

 

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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

AI voice technology has been around for years ? think Siri or Alexa ? but the magic has been missing. That?s changing, and quickly!

In this episode, Anish Acharya, General Partner at a16z, and Olivia Moore, Partner at a16z, explore why AI voice is reaching a breakthrough moment, how today?s models feel more human than ever, and why voice is poised to become the primary way people interact with AI.

With businesses already making tens of thousands of AI-driven phone calls daily, AI-powered conversations are no longer a distant vision?they?re happening now. Whether it's AI companions, customer service bots, or enterprise applications, voice tech is here?and it?s improving faster than anyone expected.

 

Resources:

Find Anish on X: https://x.com/illscience

Find Olivia on X: https://x.com/omooretweets
Read the report: https://a16z.com/ai-voice-agents-2025-update/

Listen to Raising Health?s episode on how voice AI is solving healthcare?s workforce challenges : https://a16z.com/podcast/voice-ai-solving-healthcares-workforce-challenges-with-ankit-jain/

 

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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

For over a century, the United States has been the birthplace of world-changing innovation ? from the Wright brothers? first flight to the invention of the transistor, the moon landing, and the birth of the internet. But in recent years, belief in American progress has wavered.

Three years ago, a16z General Partner Katherine Boyle wrote a bold thesis called Building American Dynamism, challenging this apathy and calling for startups to tackle the country?s biggest problems. The idea spread fast ? first as a meme, then as a movement, and today as a $600M dedicated fund.

In this episode, Katherine and fellow a16z General Partner David Ulevitch discuss:

The origins of American Dynamism?and why it was controversial at firstHow Washington and Silicon Valley can come togetherAmerica?s competitiveness in today?s great power competitionThe latest American Dynamism 50 list focused on the Indo-Pacific, showcasing the top startups building for the national interest

If you?re curious about the future of America, this is a conversation you won?t want to miss.

Check out this year?s full AD50 list at a16z.com/AD50.

 

Resources: 

Find David on X: https://x.com/davidu

Find Katherine on X: https://x.com/KTmBoyle

Find last year?s? American Dynamism 50 AI Addition? here: https://a16z.com/american-dynamism-50-ai/

Read Katherine?s article ?Building American Dynamism?: https://a16z.com/building-american-dynamism/

 

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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

Henry Ward, cofounder and CEO of Carta, has spent over a decade scaling his company from an early-stage startup to a 2,000-person industry leader. In this a16z Speedrun conversation with Games partner Josh Lu, Henry shares hard-earned lessons on:

Hiring missionaries vs. mercenaries ? and how to keep company culture intact as you scaleThe reality of product-market fit and why many founders try to sell too soonThe evolution of a CEO ? from building a product to building a system around youInputs vs. outputs, and why companies should focus on the right leading indicatorsTransparency in leadership, including when (and when not) to share

This episode is packed with candid insights and lessons on company building. Recorded live at the a16z Speedrun program, you can learn more at a16z.com/games/speedrun.

 

Resources: 

Find Henry on X: https://x.com/henrysward

Find Josh on X: https://x.com/JoshLu

 

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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

Being a creator in 2025 is tough?but building for creators is even harder. Perhaps no one understands this conundrum better than Scott Belsky. As the founder of Behance, a longtime executive at Adobe, and an advisor to companies like Pinterest and Atlassian, Scott has spent his career at the intersection of technology, design, and creativity.

In this speedrun episode, recorded live in San Francisco during the fourth iteration of our a16z Games Speedrun program, we dive into:

How AI can actually enable creators?and where its toolset should endThe evolution from the "prompt era" to the "controls era" of AIWhether people really want bespoke, personalized experiences or simply crave familiarityWhat happens when creative scarcity disappears and AI-generated content becomes ubiquitousThe future of creative tooling, from generative UI to AI-native interfaces

Plus, Scott shares insights from his time building Behance, leading product strategy at Adobe, and investing in the next generation of creative tools.

If you want to learn more about A16Z Games Speedrun, visit a16z.com/games/speedrun.

 

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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

Technology doesn?t grow in isolation?it evolves in waves. Just as mobile, cloud, and SaaS shaped the internet of the past 20 years, so too could crypto, AI, and new hardware usher in an era of the internet that?s pro-innovation, pro-startup, and pro-creator. 

Speaking with a16z Growth General Partner David George, a16z crypto Founder and Managing Partner Chris Dixon breaks down his vision for a new internet, from using crypto to decentralize AI infrastructure and kickstart network effects, to why AI will be this era?s native form of media just as film was in the 1930s. He also explores why the internet?s original covenant?where content creators traded free access for search traffic?is breaking today, and how a better internet could introduce entirely new business models for creators. 

Right now, we have a choice to make: will the next era of the internet be shaped by a handful of centralized players, or transformed into an open ecosystem where power and control flow to creators across the globe?

Resources:

Watch the conversation here: https://youtu.be/gioxu1CVjhM  

Read more, including the full transcript, here: https://a16z.com/ai-crypto-internet-chris-dixon/

Chris?s recent article on blockchain innovation: https://a16zcrypto.com/posts/article/blockchain-ai-internet/

Find Chris?s book, Read Write Own: Building the Next Era of the Internet:

Penguin Random House: https://www.penguinrandomhouse.com/books/744504/read-write-own-by-chris-dixon/

Penguin UK: https://www.penguin.co.uk/books/459860/read-write-own-by-dixon-chris/9781804949245

For more resources on AI & crypto visit: https://a16zcrypto.com/posts/?tag=ai-crypto,web2-to-web3

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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

 

Critical materials like copper, lithium, and gallium have been mined for decades, but their role in core technologies, geopolitics, and the energy transition have come to a height in recent years.

In this episode, a16z partner Connie Chan discusses how technology is changing the game of  identification and exploration, together with leading company KoBold and their VP of Geoscience, VP of Technology, and CEO of Africa.

Resources:

Learn more about KoBold Metals: https://www.koboldmetals.com/

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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

Two words have caught the Internet by storm. DeepSeek. 

The Chinese reasoning model r1 is rivaling others at the frontier with an open-source MIT license, methods that some claim may be 45x more efficient, an alleged $5.6m cost, the release of reasoning traces, a follow-on image model, and the fact that all of this was released by a hedge fund China.

Many are already referring to this as a Sputnik moment. If that?s true, how should we ? whether founder, researcher, policy maker ? not just react, but act? Joining us to tease out the signal from the noise are a16z General Partner Martin Casado and a16z board partner, Steven Sinofsky. Both Martin and Steven have been on the frontlines of prior computing cycles, from the switching wars to the fiber buildout, and have witnessed the trajectories of companies like Cisco to AOL to ATT ? even Worldcom.

So what really drove this DeepSeek frenzy and more importantly what should we take away? Today, we answer that question through the lens of Internet history.

 

Resources:

Steven?s article: DeepSeek Has Been Inevitable and Here's Why (History Tells Us)Alex Rampell?s article: Why DeepSeek Is a Gift to the American People

 

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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

This week, a16z cofounder Ben Horowitz had a rare and invaluable conversation with Dr. Clarence B. Jones, a pivotal figure in American history. 

Dr. Jones, who served as speechwriter, attorney, and advisor to Dr. Martin Luther King Jr., shared his personal insights on race, inclusion, and the lasting legacy of the civil rights movement in 2025.

In their wide-ranging discussion, Dr. Jones reflected on the timeless wisdom of Dr. King, quoting one of the most enduring lines from the "I Have a Dream" speech: ?I want my four children to be judged by the content of their character, not by the color of their skin.?

?That, to me, is still, that?s the template,? Dr. Jones said. ?That still remains a template.?

Their conversation covered critical themes in Diversity, Equity, and Inclusion, delving into the history of the movement, the lessons from "Letter from Birmingham Jail," and the profound impact Dr. King?s work continues to have today.

It was a rare opportunity to hear directly from someone who not only witnessed history but played a key role in shaping it, and we hope you enjoy it.

 

About Dr. Clarence B. Jones:

Dr. Clarence B. Jones served as legal counsel, strategic advisor, and draft speechwriter to Dr. Martin Luther King, Jr. from 1960 until Dr. King?s assassination in Memphis, Tennessee, on April 4, 1968. During that time, Dr. King depended on Dr. Jones for legal and strategic counsel and assistance in drafting landmark speeches and public testimony. He is credited with writing the first seven paragraphs of the iconic I Have A Dream speech. 

Across the decades following Dr. King?s assassination in 1968, Clarence B. Jones worked to carry on Dr. King?s legacy, to continue the nonviolent struggle for social justice, voting rights, and democratic inclusion. He is the founder of the Dr. Clarence B. Jones Institute for Social Advocacy, and also serves as the Founding Director Emeritus of the Institute for Nonviolence and Social Justice at the University of San Francisco. Dr. Jones is also the author of three acclaimed books "What Would Martin Say?", "Behind the Dream: The Making of the Speech that Transformed a Nation" and "Last of the Lions".

 

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Ben on X:  http://twitter.com/bhorowitz

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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

How is AI reshaping modern warfare? 

Speaking with a16z Growth General Partner David George, Anduril cofounder and CEO Brian Schimpf discusses how AI helps humans make better strategic decisions by sorting through the enormous amount of data collected from modern battlefields. Schimpf also discusses navigating the US government?s complex procurement processes, using commercial technologies to kickstart their own product development, and the growing opportunities for startups in defense. Throughout, Brian offers a deep dive into the intersection of technology, geopolitics, and the future of defense.

This episode is part of our AI Revolution series, where we explore how industry leaders are leveraging generative AI to steer innovation and navigate the next major platform shift. Discover more insights and content from the AI Revolution series at a16z.com/AIRevolution.

 

Resources: 

Find Brian on X: https://x.com/schimpfbrian

Find David on X: https://x.com/davidgeorge83

 

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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

Intelligent automation is transforming industries by tackling messy, unstructured workflows that traditional Robotic Process Automation (RPA) couldn?t handle. In this episode, a16z partner Kimberly Tan discusses the shift from rigid RPA systems to AI-powered agents and why this evolution unlocks massive opportunities in legacy markets.

Drawing on her article "RIP to RPA: The Rise of Intelligent Automation," Kimberly shares real-world examples of companies revolutionizing referral management, and highlights how startups can build impactful solutions in this space.

Resources:

Find Kimberly on X: https://x.com/kimberlywtan

Read Kimberly?s article: https://a16z.com/rip-to-rpa-the-rise-of-intelligent-automation/

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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

Healthcare is a $4 trillion industry, making up nearly a fifth of the U.S. economy?but despite having some of the best doctors and advanced technology, the system often delivers poor outcomes at skyrocketing costs. Why is this the case, and what will it take to fix it?

In this episode, a16z cofounder Marc Andreessen and General Partners Vijay Pande and Julie Yoo tackle some of the biggest questions shaping the future of healthcare:

Is the solution to our healthcare crisis a policy, technology, or competition problem?Will AI and technology transform the industry, or are regulatory and structural barriers too entrenched?Who will crack the code?healthcare incumbents, tech giants, or AI-native startups?

From chronic care to cost curves, from disruptive technologies to shifting patient agency, this conversation offers an unfiltered look at what?s broken in the healthcare system and how it might finally change.

Resources: 

Find Marc on X: https://x.com/pmarca

Find Vijay on X: https://x.com/vijaypande

Find Julie on X: https://x.com/julesyoo

The Biggest Company in the World

Why Will Healthcare be the Industry that Benefits Most from AI?

Grand Challenges in Healthcare AI with Vijay Pande and Julie Yoo

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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

In this episode, Substack cofounder and CEO Chris Best joins a16z General Partner Andrew Chen to discuss the origins and evolution of Substack, a platform redefining media and empowering creators to connect directly with their audiences. They dive into how Substack?s early days led to over 3 million paid subscribers, why creators are moving away from traditional platforms to establish direct connections with their audiences, and how the future of media in the AI era is reshaping opportunities for writers, podcasters, and video creators.

From Chris?s lessons scaling Kik Messaging to Substack?s profound impact on the creator economy, this conversation shares insights on building platforms, culture, and opportunity in the modern era.

 

Resources: 

Find Chris on Substack: https://cb.substack.com/

Find Andrew Chen on Substack: https://andrewchen.substack.com/

 

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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

with @sambroner @meigga @darenmatsuoka @jneu_net @chrislyons and @rhhackett @smc90

Welcome to our special end-of-year episodes -- which also look ahead to 2025 --  covering our annual Big Ideas lists, where various a16z crypto team members share what they are personally excited about. (You can see the firmwide list, also including all the trends of the crypto team,  here.)

This episode is part 1 of 2 -- but you don't have to listen to them in any particular order -- covering the trends and themes of:

stablecoins, payments, and where the early adopters will come from;app store distribution, curation, and discovery;where the next crypto users will come from, turning passive holders into active users;how builders improve, and better choose, infrastructure; andsimplifying user experience.

 Covering each of these -- and coming from the investing, go-to-market, data science, research, and media teams are:  Sam Broner, Maggie Hsu, Daren Matsuoka, Joachim Neu, and Chris Lyons; in conversation with hosts Sonal Chokshi and Robert Hackett. (Stay tuned until the end for some of our meta-commentary.) 

These are just 5 of the 14 trends we shared; you can check out the full list at a16zcrypto.com/bigideas.

Also be sure to check out part 2, which covers all the trends at the intersection of crypto and AI. 

As a reminder, none of the content is investment, business, legal, or tax advice; please see a16z.com/disclosures for more important information -- including a link to a list of our investments.

As we prepare to step into 2025, the possibilities for applied AI are reshaping industries in profound ways.

 In this episode, a16z General Partners Julie Yoo and Angela Strange, and Partner Joe Schmidt, dive into the transformative power of AI across healthcare, fintech, and traditional service sectors.

We explore:

Super Staffing for Healthcare: How AI can address critical clinical labor shortages and augment care delivery at scale.Regulation Becomes Code: The potential for AI to simplify and streamline compliance, making systems safer and more efficient.Romanticizing Inorganic Growth: The opportunity for AI-powered startups to redefine service industries through workflow automation and strategic acquisition.

With insights from a16z?s Bio + Health, Fintech, and Apps teams, this episode unpacks the ideas that will revolutionize traditional systems and unlock opportunities in 2025.

Check out the full 50 Big Ideas for 2025 at a16z.com/bigideas.

 

Resources: 

Find Angela on X: https://x.com/astrange

Find Julie on X: https://x.com/julesyoo

Find Joe on X: https://x.com/joeschmidtiv

Link to article 'The Messy Inbox Problem: Wedge Strategies in AI Apps': https://a16z.com/the-messy-inbox-problem-ai-apps-wedge-strategies

 

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Follow our host: https://twitter.com/stephsmithio

Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

The AI race is on, and 2025 could be its most transformative year yet.

In this episode, a16z General Partners Anjney Midha and Jennifer Li, and Partner Alex Immerman dive into the trends reshaping AI and its impact on search, infrastructure, and devices.

We explore:

How AI-native tools like ChatGPT and Perplexity are challenging Google?s search dominance.The rise of infrastructure independence as governments prioritize compute, energy, and data.The future of smaller, on-device AI models driving privacy, performance, and new consumer applications.

With insights from a16z?s Growth and Infrastructure teams, this episode unpacks the forces driving AI innovation?and the opportunities founders and nations could seize to lead in the next wave of technology.

Stay tuned for more in this four-part series, and explore the full 50 Big Ideas for 2025 at a16z.com/bigideas.

Resources: 

Find Alex on X: https://x.com/aleximm

FInd Anjney on X: https://x.com/AnjneyMidha

FInd Jennifer on X: https://x.com/JenniferHli

Stay Updated: 

Let us know what you think: https://ratethispodcast.com/a16z

Find a16z on Twitter: https://twitter.com/a16z

Find a16z on LinkedIn: https://www.linkedin.com/company/a16z

Subscribe on your favorite podcast app: https://a16z.simplecast.com/

Follow our host: https://twitter.com/stephsmithio

Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

As 2025 begins, industries are evolving at unprecedented speed: robots are revolutionizing manufacturing, terabytes of earth observation data are driving new possibilities, and gaming technology is transforming how we design, train, and innovate across sectors.

In this episode, a16z General Partner Erin Price-Wright, Engineering Fellow Millen Anand, and Partner Troy Kirwin discuss the trends reshaping the future of hardware, software, and beyond.

We explore:

How robots and full-stack engineers are driving the next industrial renaissance.The explosion of Earth observation data and its potential to revolutionize industries.How gaming technology is moving beyond entertainment to reshape training, design, and more.

This is just the beginning of our four-part series on 50 Big Ideas for 2025?don?t miss the full list at a16z.com/bigideas.

Resources: 

Find Erin on X: https://x.com/espricewright

Find Millen on LinkedIn: https://www.linkedin.com/in/millen-anand/

Find Troy on X: https://x.com/tkexpress11

Stay Updated: 

Let us know what you think: https://ratethispodcast.com/a16z

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Find a16z on LinkedIn: https://www.linkedin.com/company/a16z

Subscribe on your favorite podcast app: https://a16z.simplecast.com/

Follow our host: https://twitter.com/stephsmithio

Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

In this episode of Web3 with a16z, Shopify CEO and cofounder Tobias Lütke joins a16z cofounder Ben Horowitz for a conversation recorded live at the a16z crypto Founders Summit.

Together, they explore what it takes to build a breakout startup in a competitive market, the changing landscape of retail, and how to drive workplace change while navigating corporate culture and calls for activism.

Tobias shares the story behind Shopify's growth from a snowboarding store to a global ecommerce platform serving millions of merchants, discusses the moral imperative of creating great software, and offers insights on leadership, innovation, and embracing negativity as a tool for progress.

The episode also touches on the intersection of AI and crypto, the power of decentralization, and the next wave of technologies reshaping business and commerce.

 

Resources:

Find Ben on X: https://x.com/bhorowitz

Find Toni on X: https://x.com/tobi

 

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Follow our host: https://twitter.com/stephsmithio

Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

Did you know the U.S. nurse labor market is over $600 billion annually, but the dedicated software market for nurses is almost zero?

In this episode General Partners Alex Rampell, David Haber, and Angela Strange discuss how AI is revolutionizing labor by automating tasks traditionally done by humans.

They?ll trace the evolution of cloud eras ? from the original to financial services-enabled to the current AI-enabled outcomes era ? showcasing how AI is creating unprecedented opportunities, allowing startups to outpace incumbents. They also explore how this shift will reshape industries, where we are in the adoption curve and what companies need to succeed, and the gaps where the a16z Enterprise team would love to see more innovation.

Resources:

AI Turns Capital to Labor:  https://a16z.com/ai-turns-capital-to-labor/The Messy Inbox Problem: https://a16z.com/the-messy-inbox-problem-ai-apps-wedge-strategies/Vertical SaaS: Now with AI Inside: https://a16z.com/vertical-saas-now-with-ai-inside/BarbAIrians at the Gate: The Financial Opportunity of AI: https://a16z.com/financial-opportunity-of-ai/

Stay Updated:

Let us know what you think: https://ratethispodcast.com/a16zFind a16z on Twitter: https://twitter.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zSubscribe on your favorite podcast app: https://a16z.simplecast.com/Follow our host: https://twitter.com/stephsmithio

Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.a

 

Over half of Americans live in childcare deserts, while 90% of brain development happens before the age of five. All the while, education and childcare remain among the most resistant sectors to technological change. Billions of dollars have been spent, but outcomes continue to lag. Why?

In this episode, we dive into the systemic issues?misaligned incentives, political resistance, and the lack of a shared vision around the purchase of an education. We also explore how technology and entrepreneurial innovation may be shifting the tide.

You?ll hear from Anurupa Ganguly (Prisms), Chris Bennett (Wonderschool), Anna Edwards (Whiteboard Advisors), and a16z General Partner Jeff Jordan discuss the criticality of early childhood education, how public-private partnerships are required for scale, and how we can engage risk-averse decision-makers. 

Listen to learn how the next generation can reclaim the American dream.

 

Resources: 

Find Jeff on Twitter: https://x.com/jeff_jordan

Find Chris on Twitter: https://x.com/8ennett

Find Anna on LinkedIn: https://www.linkedin.com/in/annakimseyedwards/

Find Anurupa on Twitter: https://x.com/aganguly26

 

Stay Updated: 

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Follow our host: https://twitter.com/stephsmithio

Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

This episode was originally published on our sister podcast, web3 with a16z. If you?re excited about the next generation of the internet, check out the show: https://link.chtbl.com/hrr_h-XC

We've heard a lot about the premise and the promise of prediction markets for a long time, but they finally hit the main stage with the most recent election. So what worked (and didn't) this time? Are they really better than pollsters, is polling dead? 

So in this conversation, we tease apart the hype from the reality of prediction markets, from the recent election to market foundations... going more deeply into the how, why, and where these markets work. We also discuss the design challenges and opportunities (including implications for builders throughout). And we also cover other information aggregation mechanisms -- from peer prediction to others -- given that prediction markets are part of a broader category of information-elicitation and information-aggregation mechanisms. 

Where do domain experts, superforecasters, pollsters, and journalists come in (and out)? Where do (and don't) blockchain and crypto technologies come in -- and what specific features (decentralization, transparency, real-time, open source, etc.) matter most, and in what contexts?  Finally, we discuss applications for prediction and decision markets -- things we could do right away to in the near-future to sci-fi -- touching on trends like futarchy, AI entering the market, DeSci, and more.  

Our special expert guests are Alex Taborrok, professor of economics at George Mason University and Chair in Economics at the Mercatus Center; and Scott Duke Kominers, research partner at a16z crypto, and professor at Harvard Business School  -- both in conversation with Sonal Chokshi. 

As a reminder: None of the following should be taken as business, investment, legal, or tax advice; please see a16z.com/disclosures for more important information. 

 

Resources:
(from links to research mentioned to more on the topics discussed)

The Use of Knowledge in Society by Friedrich Hayek (American Economic Review, 1945)Everything is priced in by rsd99 (r/wallstreetbets, 2019)Idea Futures (aka prediction markets, information markets) by Robin Hanson (1996)Auctions: The Social Construction of Value  by Charles SmithSocial value of public information by Stephen Morris and Hyun Song Shin (American Economic Review, December 2002)Using prediction markets to estimate the reproducibility of scientific research by Anna Dreber, Thomas Pfeiffer, Johan Almenberg, Siri Isaksson, Brad Wilson, Yiling Chen, Brian Nosek, and Magnus Johannesson (Proceedings of the National Academy of Sciences (November 2015)A solution to the single-question crowd wisdom problem by Dra?en Prelec, Sebastian Seung, and John McCoy (Nature, January 2017)Targeting high ability entrepreneurs using community information: Mechanism design in the field by Reshmaan Hussam, Natalia Rigol, and Benjamin Roth (American Economic Review, March 2022)Information aggregation mechanisms: concept, design, and implementation for a sales forecasting problem by Charles Plott and Kay-Yut Chen, Hewlett Packard Laboratories (March 2002)If I had a million [on deciding to dump the CEO or not] by Robin Hanson (2008)Futarchy: Vote values, but bet beliefs by Robin Hanson (2013)From prediction markets to info finance by Vitalik Buterin (November 2024)Composability is innovation by Linda Xie (June 2021)Composability is to software as compounding interest is to finance by Chris Dixon (October 2021)resources & research on DAOs, a16z crypto

 

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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

Sales is evolving. AI-native systems are replacing traditional CRM tools, capturing unstructured insights from emails, Slack, surveys, and more in real time. These systems automate early-stage tasks like prospecting and qualification, enabling sales teams to focus on high-value work?while AI provides live coaching and drives decisions across sales, marketing, and product teams.

In this episode, a16z partners Joe Schmidt and Marc Andrusko explore the evolution of sales tools and strategies, sharing their insights on what?s driving this shift.

Is this the ?Death of a Salesforce?? Perhaps that?s an overstatement. But one thing is clear: the future belongs to those who leverage data and AI to drive decisions?not just activities.

 

Resources:

Find Marc Andrusko on X: https://x.com/mandrusko1

Find Joe Schmidt on X: https://x.com/joeschmidtiv

Read the original article: https://a16z.com/ai-transforms-sales/

 

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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

What if the biggest challenge of our time isn?t living longer, but living better? 

In this episode, we?re tackling one of humanity?s greatest accomplishments?and perhaps its most overlooked challenge: longevity. As more people live past 100, our systems?healthcare, finance, career planning, and even our cultural perceptions of aging?need a fundamental overhaul. 

We?re joined by Dr. Andrew Scott, author of The Longevity Imperative, and Vijay Pande a16z?s Bio & Health general partner, to explore how a shift from ?sick care? to ?health care? could transform our lives. Together, we discuss the implications of longer lifespans, from the individual choices that can improve our healthspans to the economic and societal shifts required to sustain a healthier, more productive aging society. 

Join us as we reimagine the future of aging, where living to 100 can be more than survival?it can be a life well-lived.

 

Resources: 

Find Andrew on X: https://x.com/profandrewscott?lang=en

Find Vijay on X: https://x.com/vijaypande

Learn more about The Longevity Imperative:

https://profandrewjscott.com/the-longevity-imperative/

 

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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

America is a country of immense wealth, but our manufacturing infrastructure is struggling to keep pace.

In this episode, we discuss the overlooked crisis of American manufacturing and what it means for our national resilience. a16z?s Oliver Hsu hosts a conversation with founders Jordan Black (Senra Systems), Chris Power (Hadrian), and Bryon Hargis (Castelion) on why we need to revive our industrial base ? and fast.

From outdated regulations to the adoption of automation, they break down the ?death by a thousand paper cuts? that has left our production capabilities lagging behind. Yet, it?s not all grim: these founders share how their companies are taking bold, vertically integrated approaches to reinvent the sector and reclaim America's industrial edge.

 

Resources:

Find Chris on X: https://x.com/2112Power

Find Jordan on X: https://x.com/jordan__black

Find Bryon on X: https://x.com/hargsb

Find Oliver on X: https://x.com/oyhsu

 

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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

2024 has been a milestone year for autonomous tech. 

Waymo?s fully autonomous driver has surpassed 20 million miles, while FAA approvals now allow commercial drones to fly without visual observers, advancing air autonomy in unprecedented ways.

In this special live recording from SF Tech Week, a16z partner Erin Price-Wright moderates a panel of experts from three key domains?air, land, and sea?to explore the latest real-world deployments of autonomous systems, the impact of new chips on cost and efficiency, building full-stack solutions, managing risk, and the evolving role of regulation in driving these technologies forward.

Joining the conversation is Macario Namie, CMO of Skydio, discussing the transition from consumer drones to enterprise and government use; Vijay Patnaik, Head of Product at Applied Intuition, who shares insights on developer tools and software for autonomous vehicles; and Peter Bowman-Davis, engineering fellow at a16z, diving into maritime autonomy based on his work at Saronic.

 

Resources: 

Find Macario on LinkedIn: https://www.linkedin.com/in/macario-namie-bb529/

Find Vijay on LinkedIn: https://www.linkedin.com/in/vijaysaipatnaik/

Find Peter on LinkedIn: https://www.linkedin.com/in/peter-bowman-davis/

Find Erin on Twitter: https://x.com/espricewright

 

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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

We take you behind the scenes of our newly released, annual State of Crypto Report ? a16z crypto's analysis of the latest data and trends that have defined the industry in 2024. 

This year's report features some brand new insights, from estimating the number of real crypto users globally, to understanding how much interest in crypto swing states may have ahead of the U.S. election. We also dig into infrastructure improvements to blockchains and key applications ? including stablecoins, AI, and so-called DePIN. Be sure to visit a16zcrypto.com for all this and more including a new ?Builder Energy? dashboard, which we?ll discuss on the show.

Joining me to talk about the findings are lead data scientist and report author Daren Matsuoka and CTO Eddy Lazzarin. The first voice you'll hear after mine is Daren's, then Eddy's.

 

a16z crypto resources:

-State of Crypto Report 2024

-Builder Energy dashboard

-Estimating the number of real crypto users

 by Daren Matsuoka and Eddy Lazzarin

 

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Find a16z on LinkedIn: https://www.linkedin.com/company/a16z

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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

 

What does Rich Sutton?s "Bitter Lesson" reveal about the decisions Tesla is making in its pursuit of autonomy?

In this episode, we dive into Tesla?s recent "We, Robot" event, where they unveiled bold plans for the unsupervised full-self-driving Cybercab, Robovan, and Optimus?their humanoid robot, which Elon Musk predicts could become ?the biggest product ever.?

Joined by a16z partners Anjney Midha and Erin Price-Wright, we explore how these announcements reflect the evolving intersection of hardware and software. We?ll unpack the layers of the autonomy stack, the sources of data powering it, and the challenges involved in making these technologies a reality.

Anjney, with his experience in computer vision and multiplayer tech at Ubiquity6, and Erin, an AI expert focused on the physical world, share their unique perspectives on how these advancements could extend far beyond the consumer market.

For more insights, check out Erin?s articles linked below. 

 

Resources: 

Find Anj on Twitter: https://x.com/anjneymidha

Find Erin on Twitter: https://x.com/espricewright

Read Erin?s article ?A Software-Driven Autonomy Stack Is Taking Shape?: https://a16z.com/a-software-driven-autonomy-stack-is-taking-shape/

AI for the Physical World: https://a16z.com/ai-for-the-physical-world/

 

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Follow our host: https://twitter.com/stephsmithio

Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

In 2024, marking 10 years since its launch, Apple Pay now boasts hundreds of millions of consumers in 78 markets, at checkout on millions of websites and apps, in tens of millions of stores worldwide, and is supported by more than 11,000 bank and network partners.

In this episode, a16z General Partner Alex Rampell sits down with Jennifer Bailey, VP of Apple Pay and Apple Wallet, to explore how Apple has transformed digital payments. 

Jennifer reveals how Apple Pay and Apple Wallet have grown beyond payments to include transit cards, car keys, and more. They also discuss the challenges of driving adoption, the future of digital wallets, and Jennifer?s insights for entrepreneurs.

 

Resources: 

Find Jennifer on LinkedIn: https://www.linkedin.com/in/jbaileyz

Find Alex on X: https://x.com/arampell

 

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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

Lisa Su has transformed AMD into a global leader in AI and high-performance computing.

In this episode of the AI Revolution (AIR) series , Bob Swan, a16z Operating Partner and former CEO of Intel, sits down with Lisa Su, CEO of AMD, to discuss how her leadership has propelled AMD?s growth and positioned the company at the forefront of AI innovation.

They explore AMD?s pivotal role in democratizing the benefits of gen AI, the evolution of AI computing, and the importance of open ecosystems and partnerships in driving technological breakthroughs.

Resources: 

Find Lisa on X: https://x.com/lisasu

Find Bob on X: https://x.com/bobswan

Stay Updated: 

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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

Deepfakes?AI-generated fake videos and voices?have become a widespread concern across politics, social media, and more. As they become easier to create, the threat grows. But so do the tools to detect them.

In this episode, Vijay Balasubramaniyan, cofounder and CEO of Pindrop, joins a16z?s Martin Casado to discuss how deepfakes work, how easily they can be made, and what defenses we have. They?ll also explore the role of policy and regulation in this rapidly changing space.

Have we lost control of the truth? Listen to find out.

Resources:

Find Vijay on Twitter: https://x.com/vijay_voice

Find Martin on Twitter: https://x.com/martin_casado

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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

Last week was another big week in technology. 

Google?s NotebookLM introduced its Audio Overview feature, enabling users to create customizable podcasts in over 35 languages. OpenAI followed with their real-time speech-to-speech API, making voice integration easier for developers, while Pika?s 1.5 model made waves in the AI world.

In this episode, we chat with the a16z Consumer team?Anish Acharya, Olivia Moore, and Bryan Kim?about the rise of voice technology, the latest AI breakthroughs, and what it takes to capture attention in 2024. Anish shares why he believes this could finally be the year of voice tech.

 

Resources: 

Find Olivia on Twitter: https://x.com/omooretweets

Find Anish on Twitter: https://x.com/illscience

Find Bryan on Twitter: https://x.com/kirbyman01

 

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Let us know what you think: https://ratethispodcast.com/a16z

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Follow our host: https://twitter.com/stephsmithio

Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

In 1995, just 2% of couples met online. Today, that number has surged to over 50%, making online dating the top way couples connect.

In this episode, a16z General Partner Andrew Chen chats with Tinder founder Sean Rad about how he built an app that changed culture. Sean shares why seamless experiences matter, how startups often get marketing wrong, and how Tinder became the catalyst for online dating's explosive growth.

This conversation was recorded live in LA at a16z?s Games third Speedrun program. Learn more about Speedrun: https://a16z.com/games/speedrun/

Find Sean on Twitter: https://x.com/seanrad

Find Andrew on Twitter: https://x.com/andrewchen

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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

What if the key to unlocking AI's full potential lies not just in algorithms or compute, but in data? 

In this episode, a16z General Partner David George sits down with Alex Wang, founder and CEO of Scale AI, to discuss the crucial role of "frontier data" in advancing artificial intelligence. From fueling breakthroughs with complex datasets to navigating the challenges of scaling AI models, Alex shares his insights on the current state of the industry and his forecast on the road to AGI.

 

Resources: 

Find Alex on Twitter: https://x.com/alexandr_wang

Find David on Twitter : https://x.com/DavidGeorge83

 

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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

Fei-Fei Li and Justin Johnson are pioneers in AI. While the world has only recently witnessed a surge in consumer AI, our guests have long been laying the groundwork for innovations that are transforming industries today.

In this episode, a16z General Partner Martin Casado joins Fei-Fei and Justin to explore the journey from early AI winters to the rise of deep learning and the rapid expansion of multimodal AI. From foundational advancements like ImageNet to the cutting-edge realm of spatial intelligence, Fei-Fei and Justin share the breakthroughs that have shaped the AI landscape and reveal what's next for innovation at World Labs.

If you're curious about how AI is evolving beyond language models and into a new realm of 3D, generative worlds, this episode is a must-listen.

Resources: 

Learn more about World Labs: https://www.worldlabs.ai

Find Fei-Fei on Twitter: https://x.com/drfeifei

Find Justin on Twitter: https://x.com/jcjohnss

Find Martin on Twitter: https://x.com/martin_casado

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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

This week in consumer tech: Apple?s big reveals, OpenAI?s multi-step reasoning, and Adobe Firefly?s video model.

Olivia Moore and Justine Moore, Partners on the a16z Consumer team, break down the latest announcements and how these product launches will shape the tech ecosystem, transform AI-powered experiences, and impact startups competing for attention in a fast-moving market.

 

Resources: 

Find Justine of Twitter: https://x.com/venturetwins

Find Olivia on Twitter: https://x.com/omooretweets

 

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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

Vijay Pande, founding general partner, and Julie Yoo, general partner at a16z Bio + Health, come together to discuss the grand challenges facing healthcare AI today.

The talk through the implications of AI integration in healthcare workflows, AI as a potential catalyst for value-based care, and the opportunity for innovation in clinical trials. They also talk about the AI startup they each wish would walk through the door. 

 

Resources: 

Find Vijay on Twitter: https://x.com/vijaypande

FInd Julie on Twitter: https://x.com/julesyoo

Listen to more episode from Raising Health: https://a16z.com/podcasts/raising-health/

 

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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

with @NoahRFeldman, @ahall_research, @rhhackett

Welcome to web3 with a16z. I'm Robert Hackett and today we have a special episode about governance in many forms ? from nation states to corporate boards to internet services and beyond.

Our special guests are Noah Feldman, constitutional law scholar at Harvard who also architected the Meta oversight board (among many other things); he is also the author of several books. And our other special guest is Andy Hall, professor of political science at Stanford who is an advisor of a16z crypto research ? and who also co-authored several papers and posts about web3 as a laboratory for designing and testing new political systems, including new work we'll link to in the shownotes.

Our hallway style conversation covers technologies and approaches to governance, from constitutions to crypto/ blockchains and DAOs. As such we also discuss content moderation and community standards; best practices for citizens assemblies; courts vs. legislatures; and much more where governance comes up. 

Throughout, we reference the history and evolution of democracy ? from Ancient Greece to the present day ? as well as examples of governance from big companies like Meta, to startups like Anthropic.

Resources for references in this episode:

On the U.S. Supreme Court case NetChoice, LLC v. Paxton (Scotusblog)On Meta's oversight board (Oversightboard.com)On Anthropic's long term benefit trust (Anthropic, September 2023)On "Boaty McBoatface" winning a boat-naming poll (Guardian, April 2016)On Athenian democracy (World History Encyclopedia, April 2018)The Three Lives of James Madison: Genius, Partisan, President by Noah Feldman (Random House, October 2017)

A selection of recent posts and papers by Andrew Hall:

The web3 governance lab: Using DAOs to study political institutions and behavior at scale by Andrew Hall and Eliza Oak (a16z crypto, June 2024)DAO research: A roadmap for experimenting with governance by Andrew Hall and Eliza Oak (a16z crypto, June 2024)The effects of retroactive rewards on participating in online governance by Andrew Hall and Eliza Oak (a16z crypto, June 2024)Lightspeed Democracy: What web3 organizations can learn from the history of governance by Andrew Hall and Porter Smith (a16z crypto, June 2023)What Kinds of Incentives Encourage Participation in Democracy? Evidence from a Massive Online Governance Experiment by Andrew Hall and Eliza Oak (working paper, November 2023)Bringing decentralized governance to tech platforms with Andrew Hall (a16z crypto Youtube, July 2022)The evolution of decentralized governance with Andrew Hall (a16z crypto Youtube, July 2022)Toppling the Internet?s Accidental Monarchs: How to Design web3 Platform Governance by Porter Smith and Andrew Hall (a16z crypto, October 2022)Paying People to Participate in Governance by Ethan Bueno de Mesquita and Andrew Hall (a16z crypto, November 2022)

As a reminder: none of the following should be taken as tax, business, legal, or investment advice. See a16zcrypto.com/disclosures for more important information, including a link to a list of our investments.

Half of prescribed medications are never taken, and 88% of Americans are metabolically unhealthy. Despite spending 20% of our GDP on healthcare?twice that of any other developed nation?our outcomes still lag behind.

In this episode, we explore why technologists must step into the healthcare ring. Solving medicine isn?t enough; we need to make healthcare a consumer-focused industry. a16z?s Vijay Pandey and Daisy Wolf discuss the rise of tech founders in healthcare, the potential of AI to transform patient care, and how this shift could lead to the next trillion-dollar company.

Can tech truly disrupt this complex, regulated industry?

 

Resources: 

Read the article ?It?s Time to Build in Healthcare?: https://a16z.com/hey-tech-its-time-to-build-in-healthcare/

Find Vijay on Twitter: https://x.com/vijaypande

Find Daisy on Twitter: https://x.com/daisydwolf

 

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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

Latin America is emerging as a tech powerhouse, but it's not a one-size-fits-all market. 

In this episode, we explore why what works in Argentina won?t necessarily fly in Brazil or Mexico, and how companies are adapting to these unique regional dynamics. Join Dileep Thazhmon, Cofounder and CEO of Jeeves; Santiago Suarez, Cofounder and CEO of Addi; Gabriel Vasquez, a16z investment partner; and Angela Strange, a16z General Partner, as they discuss the future of fintech in LatAm and the unique approach required to succeed in this diverse market.

??Whether you're interested in the nuances of product development, the complexities of scaling across diverse markets, or the future of fintech in Latin America, this episode offers perspectives from industry leaders deeply invested in the region's tech ecosystem who believe the next big tech giants might just come from Latin America.

Resources: 

Find Dileep on Twitter: https://x.com/thazhmon

Find Santiago on Twitter: https://x.com/santiasua

Find Gabriel on Twitter: https://x.com/gevs94

Find Angela on Twitter: https://x.com/astrange

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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

In this episode, we cover the recent data breach of nearly 3B records, including a significant number of social security numbers. Joining us to discuss are security experts Joel de la Garza and Naftali Harris. Incredibly enough, Naftali and his team were able to get their hands on the breached dataset and were able to validate the nature of the claims. Listen in as we explore the who, what, when, where, why? but also how a breach of this magnitude happens and what we can do about it.

Resources:

Read 16 Steps to Securing Your Data (and Life)Find Naftali on Twitter: https://x.com/naftaliharrisCheck out Sentilink: https://www.sentilink.com/

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Let us know what you think: https://ratethispodcast.com/a16zFind a16z on Twitter: https://twitter.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zSubscribe on your favorite podcast app: https://a16z.simplecast.com/Follow our host: https://twitter.com/stephsmithio

Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

This episode from Web3 with a16z Crypto, is all about innovation on a global scale, exploring both ecosystem and individual talent levels. We examine what works and what doesn?t, how certain regions evolve into startup hubs and economic powerhouses, and what constitutes entrepreneurial talent. We also discuss the nature of ambition, the journey to finding one?s path, and broader mindsets for navigating risk, reward, and dynamism across various regions, with a particular focus on London and Europe.

Joining us is Matt Clifford, who played a pivotal role in the London entrepreneurial and tech ecosystem since 2011, is the Chair of Entrepreneur First and the UK?s Advanced Research and Invention Agency (ARIA). Before this episode was recorded, Matt served as the Prime Minister?s representative for the AI Safety Summit at Bletchley Park. Recently, he was appointed by the UK Secretary of Science to deliver an ?AI Opportunities Action Plan? to the UK government.

This episode was recorded live from Andreessen Horowitz?s first international office in London. For more on our efforts and additional content, visit a16zcrypto.com/uk.

 

Resources:

Find Matthew on Twitter: https://x.com/matthewclifford

Find Sonal on Twitter: https://x.com/smc90

 

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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

Once criticized for lacking ambition, French founders are now aiming to create the world?s largest companies. With a thriving ecosystem attracting talent from across Europe and the US, France is becoming a major player on the global stage.

In this episode, we cover the unique advantages of building startups in France. Roxanne Varza, Director of Station F; Antoine Martin, co-founder of Amo and Zenly; and Brian Kim, a16z consumer partner, discuss the key factors driving this transformation, including infrastructure, community, and government support.

Discover how international talent, a supportive community, and robust governmental backing are propelling France?s startup scene. This episode is filled with insights into why France is now an exciting place to build a startup.

Resources:

Find Roxanne on Twitter: https://x.com/roxannevarza

Find Antoine on Twitter: https://x.com/an21m

Find Bryan on Twitter: https://x.com/kirbyman01

Learn more about Station F: https://stationf.co/

Learn more about Amo: https://get.amo.co/en

Stay Updated: 

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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

Waymo's autonomous vehicles have driven over 20 million miles on public roads and billions more in simulation.

In this episode, a16z General Partner David George sits down with Dmitri Dolgov, CTO at Waymo, to discuss the development of self-driving technology. Dmitri provides technical insights into the evolution of hardware and software, the impact of generative AI, and the safety standards that guide Waymo's innovations.

This footage is from AI Revolution, an event that a16z recently hosted in San Francisco. Watch the full event here:  a16z.com/dmitri-dolgov-waymo-ai

 

Resources: 

Find Dmitri on Twitter: https://x.com/dmitri_dolgov

Find David George on Twitter: https://x.com/DavidGeorge83

Learn more about Waymo: https://waymo.com/

 

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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

The Olympics features over 11,000 athletes competing in 32 sports, attracting an audience of more than 10 million.

In this episode, Charlie Ebersol, co-founder of the Alliance of American Football and Infinite Athlete, explores how new innovations like AI and bespoke broadcasting technologies are shaping the future of sports.

Charlie also reflects on the storytelling legacy of his father, Dick Ebersol, a legendary sports producer who transformed how we experience the Olympics. We discuss the importance of making sports more accessible and engaging through technology that enhances, rather than distracts from, the human stories at the heart of the games.

Whether you're a tech enthusiast or a sports fan, this episode offers a unique look at the convergence of these two worlds.

Resources: 

Find Charlie on Twitter: https://x.com/CharlieEbersol

Learn more more about Infinite Athlete: https://infiniteathlete.ai/

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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

On June 27th, the a16z team headed to New York City for the first-ever AI Artist Retreat at their office. This event brought together the builders behind some of the most popular AI creative tools, along with 16 artists, filmmakers, and designers who are exploring the capabilities of AI in their work.

In this episode, we hear from the innovators pushing the boundaries of AI creativity. Joined by Anish Acharya, General Partner, and Justine Moore, Partner on the Consumer team, we feature insights from:

Ammaar Reshi - Head of Design, ElevenLabsJustin Maier - Cofounder & CEO, CivitaiMaxfield Hulker - Cofounder & COO, CivitaiDiego Rodriguez - Cofounder & CTO, KreaVictor Perez - Cofounder & CEO, KreaMohammad Norouzi - Cofounder & CEO, IdeogramHang Chu - Cofounder & CEO, ViggleConor Durkan - Cofounder, Udio

These leaders highlight the surprising commonalities between founders and artists, and the interdisciplinary nature of their work. The episode covers the origin stories behind these innovative tools, their viral moments, and their future visions. You'll also hear about the exciting potential for AI in various creative modalities, including image, video, music, 3D, and speech.

Keep an eye out for more in our series highlighting the founders building groundbreaking foundation models and AI applications for video, audio, photography, animation, and more.

Learn more and see videos on artists leveraging AI at: 

a16z.com/aiart

 

Find Ammaar on Twitter: https://x.com/ammaar

Learn more about ElevenLabs: https://elevenlabs.io

Find Justin on Twitter: https://x.com/justmaier

Find Max on LinkedIn: https://www.linkedin.com/in/maxfield-hulker-5222aa230/
Learn more about Civitai: https://civitai.com

Find Diego on Twitter: https://x.com/asciidiego?lang=en

Find Victor on Twitter: https://x.com/viccpoes

Learn more about Krea: https://www.krea.ai/home

Find Mohammed on Twitter: https://x.com/mo_norouzi

Learn more about Ideogram: https://ideogram.ai/t/explore

Find Conor on Twitter: https://x.com/conormdurkan

Learn more about Udio: https://www.udio.com/home

Find Hang on Twitter: https://x.com/chuhang1122

Learn more about Viggle: https://viggle.ai/

 

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Find a16z on Twitter: https://twitter.com/a16z

Find a16z on LinkedIn: https://www.linkedin.com/company/a16z

Subscribe on your favorite podcast app: https://a16z.simplecast.com/

Follow our host: https://twitter.com/stephsmithio

Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

 

 

Gaming is not just entertainment?it's a revolution reshaping our culture, technology, and economy. 

a16z?s Jonathan Lai and Andrew Chen dive into the current gaming renaissance and its future impact. Joining them are Michael Chow, CEO and Steven Snow, CPO of The Believer Company, and Eros Resmini, Founder and Managing Partner of The Mini Fund.

They explore the intersection of tech, art, psychology, and design in gaming, discussing how startups can navigate intense competition, distribution challenges, and high production costs. With insights from these industry leaders, this episode covers the transformative potential of AI, the importance of player feedback, and strategies to stand out in a crowded market.

Recorded during Speedrun, a16z?s extensive games accelerator, this episode offers a glimpse into the strategies and innovations driving the gaming industry forward.

 

Resources: 

Find Steven on Twitter: https://twitter.com/StevenSnow

Find Michael on LinkedIn: https://www.linkedin.com/in/believer-paladin/

Find Eros on Twitter: https://twitter.com/erosresmini

Find Jonathan on Twitter: https://twitter.com/Tocelot

Find Andrew on Twitter: https://twitter.com/andrewchen

Learn more about Speedrun: https://a16z.com/games/speedrun/

 

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Find a16z on LinkedIn: https://www.linkedin.com/company/a16z

Subscribe on your favorite podcast app: https://a16z.simplecast.com/

Follow our host: https://twitter.com/stephsmithio

Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

Former gymnast and current investor Aly Raisman joins general partner Julie Yoo and investment partner Daisy Wolf of a16z Bio + Health.

In this episode, Aly Raisman shares her quest for healthier living?physically, mentally, and financially?on her journey from gymnast to a business investor. Having transitioned from an intensely structured routine, Aly emphasizes the need for more open conversations about mental health and financial literacy. She speaks passionately about the gap in women?s health solutions and hopes to inspire entrepreneurs to create impactful businesses. Aly?s experiences as a patient, survivor, and global figure adds a unique dimension to her perspective as an investor. This candid conversation with Aly and Julie Yoo sheds light on Aly?s passion for more education within the investment space, offering invaluable insights for entrepreneurs, particularly in biotech and healthcare.

 

Resources: 

Find Aly on Twitter: https://x.com/aly_raisman

Find Julie on Twitter: https://x.com/julesyoo

Find Daisy on Twitter: https://x.com/daisydwolf

 

Stay Updated: 

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Follow our host: https://twitter.com/stephsmithio

Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

Less than two years since the breakthrough of text-based AI, we now see incredible developments in multimodal AI models and their impact on millions of users.

As part of New York Tech Week, we brought together a live audience and three leaders from standout companies delivering AI-driven products to millions. Gaurav Misra, Cofounder and CEO of Captions, Carles Reina, Chief Revenue Officer of ElevenLabs, and Laura Burkhauser, VP of Product at Descript discuss the challenges and opportunities of designing AI-driven products, solving real customer problems, and effective marketing.

From the critical need for preventing AI misuse to ensuring international accessibility, they cover essential insights for the future of AI technology.

 

Resources: 

Find Laura on Twitter: https://x.com/burkenstocks

Find Carles on Twitter :https://twitter.com/carles_reina

Find Gaurav of Twitter: https://twitter.com/gmharhar

 

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Find a16z on LinkedIn: https://www.linkedin.com/company/a16z

Subscribe on your favorite podcast app: https://a16z.simplecast.com/

Follow our host: https://twitter.com/stephsmithio

Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.