Top 100 most popular podcasts
As 2025 begins, industries are evolving at unprecedented speed: robots are revolutionizing manufacturing, terabytes of earth observation data are driving new possibilities, and gaming technology is transforming how we design, train, and innovate across sectors.
In this episode, a16z General Partner Erin Price-Wright, Engineering Fellow Millen Anand, and Partner Troy Kirwin discuss the trends reshaping the future of hardware, software, and beyond.
We explore:
How robots and full-stack engineers are driving the next industrial renaissance.The explosion of Earth observation data and its potential to revolutionize industries.How gaming technology is moving beyond entertainment to reshape training, design, and more.This is just the beginning of our four-part series on 50 Big Ideas for 2025?don?t miss the full list at a16z.com/bigideas.
Resources:
Find Erin on X: https://x.com/espricewright
Find Millen on LinkedIn: https://www.linkedin.com/in/millen-anand/
Find Troy on X: https://x.com/tkexpress11
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
In this episode of Web3 with a16z, Shopify CEO and cofounder Tobias Lütke joins a16z cofounder Ben Horowitz for a conversation recorded live at the a16z crypto Founders Summit.
Together, they explore what it takes to build a breakout startup in a competitive market, the changing landscape of retail, and how to drive workplace change while navigating corporate culture and calls for activism.
Tobias shares the story behind Shopify's growth from a snowboarding store to a global ecommerce platform serving millions of merchants, discusses the moral imperative of creating great software, and offers insights on leadership, innovation, and embracing negativity as a tool for progress.
The episode also touches on the intersection of AI and crypto, the power of decentralization, and the next wave of technologies reshaping business and commerce.
Resources:
Find Ben on X: https://x.com/bhorowitz
Find Toni on X: https://x.com/tobi
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
Did you know the U.S. nurse labor market is over $600 billion annually, but the dedicated software market for nurses is almost zero?
In this episode General Partners Alex Rampell, David Haber, and Angela Strange discuss how AI is revolutionizing labor by automating tasks traditionally done by humans.
They?ll trace the evolution of cloud eras ? from the original to financial services-enabled to the current AI-enabled outcomes era ? showcasing how AI is creating unprecedented opportunities, allowing startups to outpace incumbents. They also explore how this shift will reshape industries, where we are in the adoption curve and what companies need to succeed, and the gaps where the a16z Enterprise team would love to see more innovation.
Resources:
AI Turns Capital to Labor: https://a16z.com/ai-turns-capital-to-labor/The Messy Inbox Problem: https://a16z.com/the-messy-inbox-problem-ai-apps-wedge-strategies/Vertical SaaS: Now with AI Inside: https://a16z.com/vertical-saas-now-with-ai-inside/BarbAIrians at the Gate: The Financial Opportunity of AI: https://a16z.com/financial-opportunity-of-ai/Stay Updated:
Let us know what you think: https://ratethispodcast.com/a16zFind a16z on Twitter: https://twitter.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zSubscribe on your favorite podcast app: https://a16z.simplecast.com/Follow our host: https://twitter.com/stephsmithioPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.a
Over half of Americans live in childcare deserts, while 90% of brain development happens before the age of five. All the while, education and childcare remain among the most resistant sectors to technological change. Billions of dollars have been spent, but outcomes continue to lag. Why?
In this episode, we dive into the systemic issues?misaligned incentives, political resistance, and the lack of a shared vision around the purchase of an education. We also explore how technology and entrepreneurial innovation may be shifting the tide.
You?ll hear from Anurupa Ganguly (Prisms), Chris Bennett (Wonderschool), Anna Edwards (Whiteboard Advisors), and a16z General Partner Jeff Jordan discuss the criticality of early childhood education, how public-private partnerships are required for scale, and how we can engage risk-averse decision-makers.
Listen to learn how the next generation can reclaim the American dream.
Resources:
Find Jeff on Twitter: https://x.com/jeff_jordan
Find Chris on Twitter: https://x.com/8ennett
Find Anna on LinkedIn: https://www.linkedin.com/in/annakimseyedwards/
Find Anurupa on Twitter: https://x.com/aganguly26
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
This episode was originally published on our sister podcast, web3 with a16z. If you?re excited about the next generation of the internet, check out the show: https://link.chtbl.com/hrr_h-XC
We've heard a lot about the premise and the promise of prediction markets for a long time, but they finally hit the main stage with the most recent election. So what worked (and didn't) this time? Are they really better than pollsters, is polling dead?
So in this conversation, we tease apart the hype from the reality of prediction markets, from the recent election to market foundations... going more deeply into the how, why, and where these markets work. We also discuss the design challenges and opportunities (including implications for builders throughout). And we also cover other information aggregation mechanisms -- from peer prediction to others -- given that prediction markets are part of a broader category of information-elicitation and information-aggregation mechanisms.
Where do domain experts, superforecasters, pollsters, and journalists come in (and out)? Where do (and don't) blockchain and crypto technologies come in -- and what specific features (decentralization, transparency, real-time, open source, etc.) matter most, and in what contexts? Finally, we discuss applications for prediction and decision markets -- things we could do right away to in the near-future to sci-fi -- touching on trends like futarchy, AI entering the market, DeSci, and more.
Our special expert guests are Alex Taborrok, professor of economics at George Mason University and Chair in Economics at the Mercatus Center; and Scott Duke Kominers, research partner at a16z crypto, and professor at Harvard Business School -- both in conversation with Sonal Chokshi.
As a reminder: None of the following should be taken as business, investment, legal, or tax advice; please see a16z.com/disclosures for more important information.
Resources:
(from links to research mentioned to more on the topics discussed)
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
Sales is evolving. AI-native systems are replacing traditional CRM tools, capturing unstructured insights from emails, Slack, surveys, and more in real time. These systems automate early-stage tasks like prospecting and qualification, enabling sales teams to focus on high-value work?while AI provides live coaching and drives decisions across sales, marketing, and product teams.
In this episode, a16z partners Joe Schmidt and Marc Andrusko explore the evolution of sales tools and strategies, sharing their insights on what?s driving this shift.
Is this the ?Death of a Salesforce?? Perhaps that?s an overstatement. But one thing is clear: the future belongs to those who leverage data and AI to drive decisions?not just activities.
Resources:
Find Marc Andrusko on X: https://x.com/mandrusko1
Find Joe Schmidt on X: https://x.com/joeschmidtiv
Read the original article: https://a16z.com/ai-transforms-sales/
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
What if the biggest challenge of our time isn?t living longer, but living better?
In this episode, we?re tackling one of humanity?s greatest accomplishments?and perhaps its most overlooked challenge: longevity. As more people live past 100, our systems?healthcare, finance, career planning, and even our cultural perceptions of aging?need a fundamental overhaul.
We?re joined by Dr. Andrew Scott, author of The Longevity Imperative, and Vijay Pande a16z?s Bio & Health general partner, to explore how a shift from ?sick care? to ?health care? could transform our lives. Together, we discuss the implications of longer lifespans, from the individual choices that can improve our healthspans to the economic and societal shifts required to sustain a healthier, more productive aging society.
Join us as we reimagine the future of aging, where living to 100 can be more than survival?it can be a life well-lived.
Resources:
Find Andrew on X: https://x.com/profandrewscott?lang=en
Find Vijay on X: https://x.com/vijaypande
Learn more about The Longevity Imperative:
https://profandrewjscott.com/the-longevity-imperative/
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
America is a country of immense wealth, but our manufacturing infrastructure is struggling to keep pace.
In this episode, we discuss the overlooked crisis of American manufacturing and what it means for our national resilience. a16z?s Oliver Hsu hosts a conversation with founders Jordan Black (Senra Systems), Chris Power (Hadrian), and Bryon Hargis (Castelion) on why we need to revive our industrial base ? and fast.
From outdated regulations to the adoption of automation, they break down the ?death by a thousand paper cuts? that has left our production capabilities lagging behind. Yet, it?s not all grim: these founders share how their companies are taking bold, vertically integrated approaches to reinvent the sector and reclaim America's industrial edge.
Resources:
Find Chris on X: https://x.com/2112Power
Find Jordan on X: https://x.com/jordan__black
Find Bryon on X: https://x.com/hargsb
Find Oliver on X: https://x.com/oyhsu
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
2024 has been a milestone year for autonomous tech.
Waymo?s fully autonomous driver has surpassed 20 million miles, while FAA approvals now allow commercial drones to fly without visual observers, advancing air autonomy in unprecedented ways.
In this special live recording from SF Tech Week, a16z partner Erin Price-Wright moderates a panel of experts from three key domains?air, land, and sea?to explore the latest real-world deployments of autonomous systems, the impact of new chips on cost and efficiency, building full-stack solutions, managing risk, and the evolving role of regulation in driving these technologies forward.
Joining the conversation is Macario Namie, CMO of Skydio, discussing the transition from consumer drones to enterprise and government use; Vijay Patnaik, Head of Product at Applied Intuition, who shares insights on developer tools and software for autonomous vehicles; and Peter Bowman-Davis, engineering fellow at a16z, diving into maritime autonomy based on his work at Saronic.
Resources:
Find Macario on LinkedIn: https://www.linkedin.com/in/macario-namie-bb529/
Find Vijay on LinkedIn: https://www.linkedin.com/in/vijaysaipatnaik/
Find Peter on LinkedIn: https://www.linkedin.com/in/peter-bowman-davis/
Find Erin on Twitter: https://x.com/espricewright
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
We take you behind the scenes of our newly released, annual State of Crypto Report ? a16z crypto's analysis of the latest data and trends that have defined the industry in 2024.
This year's report features some brand new insights, from estimating the number of real crypto users globally, to understanding how much interest in crypto swing states may have ahead of the U.S. election. We also dig into infrastructure improvements to blockchains and key applications ? including stablecoins, AI, and so-called DePIN. Be sure to visit a16zcrypto.com for all this and more including a new ?Builder Energy? dashboard, which we?ll discuss on the show.
Joining me to talk about the findings are lead data scientist and report author Daren Matsuoka and CTO Eddy Lazzarin. The first voice you'll hear after mine is Daren's, then Eddy's.
a16z crypto resources:
-Estimating the number of real crypto users
by Daren Matsuoka and Eddy Lazzarin
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
What does Rich Sutton?s "Bitter Lesson" reveal about the decisions Tesla is making in its pursuit of autonomy?
In this episode, we dive into Tesla?s recent "We, Robot" event, where they unveiled bold plans for the unsupervised full-self-driving Cybercab, Robovan, and Optimus?their humanoid robot, which Elon Musk predicts could become ?the biggest product ever.?
Joined by a16z partners Anjney Midha and Erin Price-Wright, we explore how these announcements reflect the evolving intersection of hardware and software. We?ll unpack the layers of the autonomy stack, the sources of data powering it, and the challenges involved in making these technologies a reality.
Anjney, with his experience in computer vision and multiplayer tech at Ubiquity6, and Erin, an AI expert focused on the physical world, share their unique perspectives on how these advancements could extend far beyond the consumer market.
For more insights, check out Erin?s articles linked below.
Resources:
Find Anj on Twitter: https://x.com/anjneymidha
Find Erin on Twitter: https://x.com/espricewright
Read Erin?s article ?A Software-Driven Autonomy Stack Is Taking Shape?: https://a16z.com/a-software-driven-autonomy-stack-is-taking-shape/
AI for the Physical World: https://a16z.com/ai-for-the-physical-world/
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
In 2024, marking 10 years since its launch, Apple Pay now boasts hundreds of millions of consumers in 78 markets, at checkout on millions of websites and apps, in tens of millions of stores worldwide, and is supported by more than 11,000 bank and network partners.
In this episode, a16z General Partner Alex Rampell sits down with Jennifer Bailey, VP of Apple Pay and Apple Wallet, to explore how Apple has transformed digital payments.
Jennifer reveals how Apple Pay and Apple Wallet have grown beyond payments to include transit cards, car keys, and more. They also discuss the challenges of driving adoption, the future of digital wallets, and Jennifer?s insights for entrepreneurs.
Resources:
Find Jennifer on LinkedIn: https://www.linkedin.com/in/jbaileyz
Find Alex on X: https://x.com/arampell
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
Lisa Su has transformed AMD into a global leader in AI and high-performance computing.
In this episode of the AI Revolution (AIR) series , Bob Swan, a16z Operating Partner and former CEO of Intel, sits down with Lisa Su, CEO of AMD, to discuss how her leadership has propelled AMD?s growth and positioned the company at the forefront of AI innovation.
They explore AMD?s pivotal role in democratizing the benefits of gen AI, the evolution of AI computing, and the importance of open ecosystems and partnerships in driving technological breakthroughs.
Resources:
Find Lisa on X: https://x.com/lisasu
Find Bob on X: https://x.com/bobswan
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
Deepfakes?AI-generated fake videos and voices?have become a widespread concern across politics, social media, and more. As they become easier to create, the threat grows. But so do the tools to detect them.
In this episode, Vijay Balasubramaniyan, cofounder and CEO of Pindrop, joins a16z?s Martin Casado to discuss how deepfakes work, how easily they can be made, and what defenses we have. They?ll also explore the role of policy and regulation in this rapidly changing space.
Have we lost control of the truth? Listen to find out.
Resources:
Find Vijay on Twitter: https://x.com/vijay_voice
Find Martin on Twitter: https://x.com/martin_casado
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
Last week was another big week in technology.
Google?s NotebookLM introduced its Audio Overview feature, enabling users to create customizable podcasts in over 35 languages. OpenAI followed with their real-time speech-to-speech API, making voice integration easier for developers, while Pika?s 1.5 model made waves in the AI world.
In this episode, we chat with the a16z Consumer team?Anish Acharya, Olivia Moore, and Bryan Kim?about the rise of voice technology, the latest AI breakthroughs, and what it takes to capture attention in 2024. Anish shares why he believes this could finally be the year of voice tech.
Resources:
Find Olivia on Twitter: https://x.com/omooretweets
Find Anish on Twitter: https://x.com/illscience
Find Bryan on Twitter: https://x.com/kirbyman01
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
In 1995, just 2% of couples met online. Today, that number has surged to over 50%, making online dating the top way couples connect.
In this episode, a16z General Partner Andrew Chen chats with Tinder founder Sean Rad about how he built an app that changed culture. Sean shares why seamless experiences matter, how startups often get marketing wrong, and how Tinder became the catalyst for online dating's explosive growth.
This conversation was recorded live in LA at a16z?s Games third Speedrun program. Learn more about Speedrun: https://a16z.com/games/speedrun/
Find Sean on Twitter: https://x.com/seanrad
Find Andrew on Twitter: https://x.com/andrewchen
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
What if the key to unlocking AI's full potential lies not just in algorithms or compute, but in data?
In this episode, a16z General Partner David George sits down with Alex Wang, founder and CEO of Scale AI, to discuss the crucial role of "frontier data" in advancing artificial intelligence. From fueling breakthroughs with complex datasets to navigating the challenges of scaling AI models, Alex shares his insights on the current state of the industry and his forecast on the road to AGI.
Resources:
Find Alex on Twitter: https://x.com/alexandr_wang
Find David on Twitter : https://x.com/DavidGeorge83
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
Fei-Fei Li and Justin Johnson are pioneers in AI. While the world has only recently witnessed a surge in consumer AI, our guests have long been laying the groundwork for innovations that are transforming industries today.
In this episode, a16z General Partner Martin Casado joins Fei-Fei and Justin to explore the journey from early AI winters to the rise of deep learning and the rapid expansion of multimodal AI. From foundational advancements like ImageNet to the cutting-edge realm of spatial intelligence, Fei-Fei and Justin share the breakthroughs that have shaped the AI landscape and reveal what's next for innovation at World Labs.
If you're curious about how AI is evolving beyond language models and into a new realm of 3D, generative worlds, this episode is a must-listen.
Resources:
Learn more about World Labs: https://www.worldlabs.ai
Find Fei-Fei on Twitter: https://x.com/drfeifei
Find Justin on Twitter: https://x.com/jcjohnss
Find Martin on Twitter: https://x.com/martin_casado
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
This week in consumer tech: Apple?s big reveals, OpenAI?s multi-step reasoning, and Adobe Firefly?s video model.
Olivia Moore and Justine Moore, Partners on the a16z Consumer team, break down the latest announcements and how these product launches will shape the tech ecosystem, transform AI-powered experiences, and impact startups competing for attention in a fast-moving market.
Resources:
Find Justine of Twitter: https://x.com/venturetwins
Find Olivia on Twitter: https://x.com/omooretweets
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
Vijay Pande, founding general partner, and Julie Yoo, general partner at a16z Bio + Health, come together to discuss the grand challenges facing healthcare AI today.
The talk through the implications of AI integration in healthcare workflows, AI as a potential catalyst for value-based care, and the opportunity for innovation in clinical trials. They also talk about the AI startup they each wish would walk through the door.
Resources:
Find Vijay on Twitter: https://x.com/vijaypande
FInd Julie on Twitter: https://x.com/julesyoo
Listen to more episode from Raising Health: https://a16z.com/podcasts/raising-health/
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
with @NoahRFeldman, @ahall_research, @rhhackett
Welcome to web3 with a16z. I'm Robert Hackett and today we have a special episode about governance in many forms ? from nation states to corporate boards to internet services and beyond.
Our special guests are Noah Feldman, constitutional law scholar at Harvard who also architected the Meta oversight board (among many other things); he is also the author of several books. And our other special guest is Andy Hall, professor of political science at Stanford who is an advisor of a16z crypto research ? and who also co-authored several papers and posts about web3 as a laboratory for designing and testing new political systems, including new work we'll link to in the shownotes.
Our hallway style conversation covers technologies and approaches to governance, from constitutions to crypto/ blockchains and DAOs. As such we also discuss content moderation and community standards; best practices for citizens assemblies; courts vs. legislatures; and much more where governance comes up.
Throughout, we reference the history and evolution of democracy ? from Ancient Greece to the present day ? as well as examples of governance from big companies like Meta, to startups like Anthropic.
Resources for references in this episode:
On the U.S. Supreme Court case NetChoice, LLC v. Paxton (Scotusblog)On Meta's oversight board (Oversightboard.com)On Anthropic's long term benefit trust (Anthropic, September 2023)On "Boaty McBoatface" winning a boat-naming poll (Guardian, April 2016)On Athenian democracy (World History Encyclopedia, April 2018)The Three Lives of James Madison: Genius, Partisan, President by Noah Feldman (Random House, October 2017)A selection of recent posts and papers by Andrew Hall:
The web3 governance lab: Using DAOs to study political institutions and behavior at scale by Andrew Hall and Eliza Oak (a16z crypto, June 2024)DAO research: A roadmap for experimenting with governance by Andrew Hall and Eliza Oak (a16z crypto, June 2024)The effects of retroactive rewards on participating in online governance by Andrew Hall and Eliza Oak (a16z crypto, June 2024)Lightspeed Democracy: What web3 organizations can learn from the history of governance by Andrew Hall and Porter Smith (a16z crypto, June 2023)What Kinds of Incentives Encourage Participation in Democracy? Evidence from a Massive Online Governance Experiment by Andrew Hall and Eliza Oak (working paper, November 2023)Bringing decentralized governance to tech platforms with Andrew Hall (a16z crypto Youtube, July 2022)The evolution of decentralized governance with Andrew Hall (a16z crypto Youtube, July 2022)Toppling the Internet?s Accidental Monarchs: How to Design web3 Platform Governance by Porter Smith and Andrew Hall (a16z crypto, October 2022)Paying People to Participate in Governance by Ethan Bueno de Mesquita and Andrew Hall (a16z crypto, November 2022)As a reminder: none of the following should be taken as tax, business, legal, or investment advice. See a16zcrypto.com/disclosures for more important information, including a link to a list of our investments.
Half of prescribed medications are never taken, and 88% of Americans are metabolically unhealthy. Despite spending 20% of our GDP on healthcare?twice that of any other developed nation?our outcomes still lag behind.
In this episode, we explore why technologists must step into the healthcare ring. Solving medicine isn?t enough; we need to make healthcare a consumer-focused industry. a16z?s Vijay Pandey and Daisy Wolf discuss the rise of tech founders in healthcare, the potential of AI to transform patient care, and how this shift could lead to the next trillion-dollar company.
Can tech truly disrupt this complex, regulated industry?
Resources:
Read the article ?It?s Time to Build in Healthcare?: https://a16z.com/hey-tech-its-time-to-build-in-healthcare/
Find Vijay on Twitter: https://x.com/vijaypande
Find Daisy on Twitter: https://x.com/daisydwolf
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
Latin America is emerging as a tech powerhouse, but it's not a one-size-fits-all market.
In this episode, we explore why what works in Argentina won?t necessarily fly in Brazil or Mexico, and how companies are adapting to these unique regional dynamics. Join Dileep Thazhmon, Cofounder and CEO of Jeeves; Santiago Suarez, Cofounder and CEO of Addi; Gabriel Vasquez, a16z investment partner; and Angela Strange, a16z General Partner, as they discuss the future of fintech in LatAm and the unique approach required to succeed in this diverse market.
??Whether you're interested in the nuances of product development, the complexities of scaling across diverse markets, or the future of fintech in Latin America, this episode offers perspectives from industry leaders deeply invested in the region's tech ecosystem who believe the next big tech giants might just come from Latin America.
Resources:
Find Dileep on Twitter: https://x.com/thazhmon
Find Santiago on Twitter: https://x.com/santiasua
Find Gabriel on Twitter: https://x.com/gevs94
Find Angela on Twitter: https://x.com/astrange
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
In this episode, we cover the recent data breach of nearly 3B records, including a significant number of social security numbers. Joining us to discuss are security experts Joel de la Garza and Naftali Harris. Incredibly enough, Naftali and his team were able to get their hands on the breached dataset and were able to validate the nature of the claims. Listen in as we explore the who, what, when, where, why? but also how a breach of this magnitude happens and what we can do about it.
Resources:
Read 16 Steps to Securing Your Data (and Life)Find Naftali on Twitter: https://x.com/naftaliharrisCheck out Sentilink: https://www.sentilink.com/Stay Updated:
Let us know what you think: https://ratethispodcast.com/a16zFind a16z on Twitter: https://twitter.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zSubscribe on your favorite podcast app: https://a16z.simplecast.com/Follow our host: https://twitter.com/stephsmithioPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
This episode from Web3 with a16z Crypto, is all about innovation on a global scale, exploring both ecosystem and individual talent levels. We examine what works and what doesn?t, how certain regions evolve into startup hubs and economic powerhouses, and what constitutes entrepreneurial talent. We also discuss the nature of ambition, the journey to finding one?s path, and broader mindsets for navigating risk, reward, and dynamism across various regions, with a particular focus on London and Europe.
Joining us is Matt Clifford, who played a pivotal role in the London entrepreneurial and tech ecosystem since 2011, is the Chair of Entrepreneur First and the UK?s Advanced Research and Invention Agency (ARIA). Before this episode was recorded, Matt served as the Prime Minister?s representative for the AI Safety Summit at Bletchley Park. Recently, he was appointed by the UK Secretary of Science to deliver an ?AI Opportunities Action Plan? to the UK government.
This episode was recorded live from Andreessen Horowitz?s first international office in London. For more on our efforts and additional content, visit a16zcrypto.com/uk.
Resources:
Find Matthew on Twitter: https://x.com/matthewclifford
Find Sonal on Twitter: https://x.com/smc90
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
Once criticized for lacking ambition, French founders are now aiming to create the world?s largest companies. With a thriving ecosystem attracting talent from across Europe and the US, France is becoming a major player on the global stage.
In this episode, we cover the unique advantages of building startups in France. Roxanne Varza, Director of Station F; Antoine Martin, co-founder of Amo and Zenly; and Brian Kim, a16z consumer partner, discuss the key factors driving this transformation, including infrastructure, community, and government support.
Discover how international talent, a supportive community, and robust governmental backing are propelling France?s startup scene. This episode is filled with insights into why France is now an exciting place to build a startup.
Resources:
Find Roxanne on Twitter: https://x.com/roxannevarza
Find Antoine on Twitter: https://x.com/an21m
Find Bryan on Twitter: https://x.com/kirbyman01
Learn more about Station F: https://stationf.co/
Learn more about Amo: https://get.amo.co/en
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Follow our host: https://twitter.com/stephsmithio
Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
Waymo's autonomous vehicles have driven over 20 million miles on public roads and billions more in simulation.
In this episode, a16z General Partner David George sits down with Dmitri Dolgov, CTO at Waymo, to discuss the development of self-driving technology. Dmitri provides technical insights into the evolution of hardware and software, the impact of generative AI, and the safety standards that guide Waymo's innovations.
This footage is from AI Revolution, an event that a16z recently hosted in San Francisco. Watch the full event here: a16z.com/dmitri-dolgov-waymo-ai
Resources:
Find Dmitri on Twitter: https://x.com/dmitri_dolgov
Find David George on Twitter: https://x.com/DavidGeorge83
Learn more about Waymo: https://waymo.com/
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
The Olympics features over 11,000 athletes competing in 32 sports, attracting an audience of more than 10 million.
In this episode, Charlie Ebersol, co-founder of the Alliance of American Football and Infinite Athlete, explores how new innovations like AI and bespoke broadcasting technologies are shaping the future of sports.
Charlie also reflects on the storytelling legacy of his father, Dick Ebersol, a legendary sports producer who transformed how we experience the Olympics. We discuss the importance of making sports more accessible and engaging through technology that enhances, rather than distracts from, the human stories at the heart of the games.
Whether you're a tech enthusiast or a sports fan, this episode offers a unique look at the convergence of these two worlds.
Resources:
Find Charlie on Twitter: https://x.com/CharlieEbersol
Learn more more about Infinite Athlete: https://infiniteathlete.ai/
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
On June 27th, the a16z team headed to New York City for the first-ever AI Artist Retreat at their office. This event brought together the builders behind some of the most popular AI creative tools, along with 16 artists, filmmakers, and designers who are exploring the capabilities of AI in their work.
In this episode, we hear from the innovators pushing the boundaries of AI creativity. Joined by Anish Acharya, General Partner, and Justine Moore, Partner on the Consumer team, we feature insights from:
Ammaar Reshi - Head of Design, ElevenLabsJustin Maier - Cofounder & CEO, CivitaiMaxfield Hulker - Cofounder & COO, CivitaiDiego Rodriguez - Cofounder & CTO, KreaVictor Perez - Cofounder & CEO, KreaMohammad Norouzi - Cofounder & CEO, IdeogramHang Chu - Cofounder & CEO, ViggleConor Durkan - Cofounder, UdioThese leaders highlight the surprising commonalities between founders and artists, and the interdisciplinary nature of their work. The episode covers the origin stories behind these innovative tools, their viral moments, and their future visions. You'll also hear about the exciting potential for AI in various creative modalities, including image, video, music, 3D, and speech.
Keep an eye out for more in our series highlighting the founders building groundbreaking foundation models and AI applications for video, audio, photography, animation, and more.
Learn more and see videos on artists leveraging AI at:
Find Ammaar on Twitter: https://x.com/ammaar
Learn more about ElevenLabs: https://elevenlabs.io
Find Justin on Twitter: https://x.com/justmaier
Find Max on LinkedIn: https://www.linkedin.com/in/maxfield-hulker-5222aa230/
Learn more about Civitai: https://civitai.com
Find Diego on Twitter: https://x.com/asciidiego?lang=en
Find Victor on Twitter: https://x.com/viccpoes
Learn more about Krea: https://www.krea.ai/home
Find Mohammed on Twitter: https://x.com/mo_norouzi
Learn more about Ideogram: https://ideogram.ai/t/explore
Find Conor on Twitter: https://x.com/conormdurkan
Learn more about Udio: https://www.udio.com/home
Find Hang on Twitter: https://x.com/chuhang1122
Learn more about Viggle: https://viggle.ai/
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Find a16z on LinkedIn: https://www.linkedin.com/company/a16z
Subscribe on your favorite podcast app: https://a16z.simplecast.com/
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
Gaming is not just entertainment?it's a revolution reshaping our culture, technology, and economy.
a16z?s Jonathan Lai and Andrew Chen dive into the current gaming renaissance and its future impact. Joining them are Michael Chow, CEO and Steven Snow, CPO of The Believer Company, and Eros Resmini, Founder and Managing Partner of The Mini Fund.
They explore the intersection of tech, art, psychology, and design in gaming, discussing how startups can navigate intense competition, distribution challenges, and high production costs. With insights from these industry leaders, this episode covers the transformative potential of AI, the importance of player feedback, and strategies to stand out in a crowded market.
Recorded during Speedrun, a16z?s extensive games accelerator, this episode offers a glimpse into the strategies and innovations driving the gaming industry forward.
Resources:
Find Steven on Twitter: https://twitter.com/StevenSnow
Find Michael on LinkedIn: https://www.linkedin.com/in/believer-paladin/
Find Eros on Twitter: https://twitter.com/erosresmini
Find Jonathan on Twitter: https://twitter.com/Tocelot
Find Andrew on Twitter: https://twitter.com/andrewchen
Learn more about Speedrun: https://a16z.com/games/speedrun/
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Find a16z on LinkedIn: https://www.linkedin.com/company/a16z
Subscribe on your favorite podcast app: https://a16z.simplecast.com/
Follow our host: https://twitter.com/stephsmithio
Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
Former gymnast and current investor Aly Raisman joins general partner Julie Yoo and investment partner Daisy Wolf of a16z Bio + Health.
In this episode, Aly Raisman shares her quest for healthier living?physically, mentally, and financially?on her journey from gymnast to a business investor. Having transitioned from an intensely structured routine, Aly emphasizes the need for more open conversations about mental health and financial literacy. She speaks passionately about the gap in women?s health solutions and hopes to inspire entrepreneurs to create impactful businesses. Aly?s experiences as a patient, survivor, and global figure adds a unique dimension to her perspective as an investor. This candid conversation with Aly and Julie Yoo sheds light on Aly?s passion for more education within the investment space, offering invaluable insights for entrepreneurs, particularly in biotech and healthcare.
Resources:
Find Aly on Twitter: https://x.com/aly_raisman
Find Julie on Twitter: https://x.com/julesyoo
Find Daisy on Twitter: https://x.com/daisydwolf
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Subscribe on your favorite podcast app: https://a16z.simplecast.com/
Follow our host: https://twitter.com/stephsmithio
Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
Less than two years since the breakthrough of text-based AI, we now see incredible developments in multimodal AI models and their impact on millions of users.
As part of New York Tech Week, we brought together a live audience and three leaders from standout companies delivering AI-driven products to millions. Gaurav Misra, Cofounder and CEO of Captions, Carles Reina, Chief Revenue Officer of ElevenLabs, and Laura Burkhauser, VP of Product at Descript discuss the challenges and opportunities of designing AI-driven products, solving real customer problems, and effective marketing.
From the critical need for preventing AI misuse to ensuring international accessibility, they cover essential insights for the future of AI technology.
Resources:
Find Laura on Twitter: https://x.com/burkenstocks
Find Carles on Twitter :https://twitter.com/carles_reina
Find Gaurav of Twitter: https://twitter.com/gmharhar
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Subscribe on your favorite podcast app: https://a16z.simplecast.com/
Follow our host: https://twitter.com/stephsmithio
Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
"The Ben & Marc Show," featuring a16z co-founders Marc Andreessen and Ben Horowitz.
In this special episode, Marc and Ben dive deep into the REAL story behind the creation of Netscape?a web browser co-created by Marc that revolutionized the internet and changed the world. As Ben notes at the top, until today, this story has never been fully told either in its entirety or accurately.
In this one-on-one conversation, Marc and Ben discuss Marc's early life and how it shaped his journey into technology, the pivotal moments at the University of Illinois that led to the development of Mosaic (a renegade browser that Marc developed as an undergrad), and the fierce competition and legal battles that ensued as Netscape rose to prominence.
Ben and Marc also reflect on the broader implications of Netscape's success, the importance of an open internet, and the lessons learned that still resonate in today's tech landscape (especially with AI). That and much more. Enjoy!
Watch the FULL Episode on YouTune: https://youtu.be/8aTjA_bGZO4
Resources:
Marc on X: https://twitter.com/pmarca
Marc?s Substack: https://pmarca.substack.com/
Ben on X: https://twitter.com/bhorowitz
Book mentioned on this episode:
- ?Expert Political Judgment? by Philip E. Tetlock https://bit.ly/45KzP6M
TV Series mentioned on this episode:
- ?The Mandalorian? (Disney+) https://bit.ly/3W0Zyoq
Stay Updated:
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
We know that technology has changed art, and that artists have evolved with every new technology ? it?s a tale as old as humanity, moving from cave paintings to computers. Underlying these movements are endless debates around inventing versus remixing; between commercialism and art; between mainstream canon and fringe art; whether we?re living in an artistic monoculture now (the answer may surprise you); and much much more.
So in this new episode featuring Berlin-based contemporary artist Simon Denny -- in conversation with a16z crypto editor in chief Sonal Chokshi -- we discuss all of the above debates. We also cover how artists experimented with the emergence of new technology platforms like the web browser, the iPhone, Instagram and social media; to how generative art found its ?native? medium on blockchains, why NFTs; and other art movements.
Denny also thinks of entrepreneurial ideas -- from Peter Thiel's to Chris Dixon's Read Write Own -- as an "aesthetic"; and thinks of technology artifacts (like NSA sketches!) as art -- reflecting all of these in his works across various mediums and contexts. How has technology changed art, and more importantly, how have artists changed with technology? How does art change our place in the world, or span beyond space? It's about optimism, and seeing things anew... all this and more in this episode.
Resources:
Find Denny on Twitter: https://x.com/dennnnnnnnny
Find Sonal on Twitter: https://x.com/smc90
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
Is it time to hand over cybersecurity to machines amidst the exponential rise in cyber threats and breaches?
We trace the evolution of cybersecurity from minimal measures in 1995 to today's overwhelmed DevSecOps. Travis McPeak, CEO and Co-founder of Resourcely, kicks off our discussion by discussing the historical shifts in the industry. Kevin Tian, CEO and Founder of Doppel, highlights the rise of AI-driven threats and deepfake campaigns. Feross Aboukhadijeh, CEO and Founder of Socket, provides insights into sophisticated attacks like the XZ Utils incident. Andrej Safundzic, CEO and Founder of Lumos, discusses the future of autonomous security systems and their impact on startups.
Recorded at a16z's Campfire Sessions, these top security experts share the real challenges they face and emphasize the need for a new approach.
Resources:
Find Travis McPeak on Twitter: https://x.com/travismcpeak
Find Kevin Tian on Twitter: https://twitter.com/kevintian00
Find Feross Aboukhadijeh on Twitter: https://x.com/feross
Find Andrej Safundzic on Twitter: https://x.com/andrejsafundzic
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Subscribe on your favorite podcast app: https://a16z.simplecast.com/
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
Brooke Boyarsky Pratt, founder and CEO of knownwell, joins Vineeta Agarwala, general partner at a16z Bio + Health.
Together, they talk about the value of obesity medicine practitioners, patient-centric medical homes, and how Brooke believes the metabolic health space will evolve over time.
This is the second episode in Raising Health?s series on the science and supply of GLP-1s. Listen to last week's episode to hear from Carolyn Jasik, Chief Medical Officer at Omada Health, on GLP-1s from a clinical perspective.
Listen to more from Raising Health?s series on GLP-1s:
The science of satiety: https://raisinghealth.simplecast.com/episodes/the-science-and-supply-of-glp-1s-with-carolyn-jasik
Payers, providers and pricing: https://raisinghealth.simplecast.com/episodes/the-science-and-supply-of-glp-1s-with-chronis-manolis
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
In this latest episode on the State of AI, Ben and Marc discuss how small AI startups can compete with Big Tech?s massive compute and data scale advantages, reveal why data is overrated as a sellable asset, and unpack all the ways the AI boom compares to the internet boom.
Subscribe to the Ben & Marc podcast: https://link.chtbl.com/benandmarc
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
Over the past decade, usage-based pricing has soared in popularity. Why? Because it aligns cost with value, letting customers pay only for what they use. But, that flexibility is not without issues - especially when it comes to predicting revenue. Fortunately, with the right process and infrastructure, your usage-based revenue can become more predictable than the traditional seat-based SaaS model.
In this episode from the a16z Growth team, Fivetran?s VP of Strategy and Operations Travis Ferber and Alchemy?s Head of Sales Dan Burrill join a16z Growth?s Revenue Operations Partner Mark Regan. Together, they discuss the art of generating reliable usage-based revenue. They share tips for avoiding common pitfalls when implementing this pricing model - including how to nail sales forecasting, adopting the best tools to track usage, and deal with the initial lack of customer data.
Resources:
Learn more about pricing, packaging, and monetization strategies: a16z.com/pricing-packaging
Find Dan on Twitter: https://twitter.com/BurrillDaniel
Find Travis on LinkedIn: https://www.linkedin.com/in/travisferber
Find Mark on LinkedIn: https://www.linkedin.com/in/mregan178
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
On May 21, the California Senate passed bill 1047.
This bill ? which sets out to regulate AI at the model level ? wasn?t garnering much attention, until it slid through an overwhelming bipartisan vote of 32 to 1 and is now queued for an assembly vote in August that would cement it into law. In this episode, a16z General Partner Anjney Midha and Venture Editor Derrick Harris breakdown everything the tech community needs to know about SB-1047.
This bill really is the tip of the iceberg, with over 600 new pieces of AI legislation swirling in the United States. So if you care about one of the most important technologies of our generation and America?s ability to continue leading the charge here, we encourage you to read the bill and spread the word.
Read the bill: https://leginfo.legislature.ca.gov/faces/billTextClient.xhtml?bill_id=202320240SB1047
Consumer AI is moving fast, so who's leading the charge?
a16z Consumer Partners Olivia Moore and Bryan Kim discuss our GenAI 100 list and what it takes for an AI model to stand out and dominate the market.
They discuss how these cutting-edge apps are connecting with their users and debate whether traditional strategies like paid acquisition and network effects are still effective. We're going beyond rankings to explore pivotal benchmarks like D7 retention and introduce metrics that define today's AI market.
Note: This episode was recorded prior to OpenAI's Spring update. Catch our latest insights in the previous episode to stay ahead!
Resources:
Link to the Gen AI 100: https://a16z.com/100-gen-ai-apps
Find Bryan on Twitter: https://twitter.com/kirbyman01
Find Olivia on Twitter: https://x.com/omooretweets
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
a16z General Partner David Haber talks with Marty Chavez, vice chairman and partner at Sixth Street Partners, about the foundational role he?s had in merging technology and finance throughout his career, and the magical promises and regulatory pitfalls of AI.
This episode is taken from ?In the Vault?, a new audio podcast series by the a16z Fintech team. Each episode features the most influential figures in financial services to explore key trends impacting the industry and the pressing innovations that will shape our future.
Resources:
Listen to more of In the Vault: https://a16z.com/podcasts/a16z-live
Find Marty on X: https://twitter.com/rmartinchavez
Find David on X: https://twitter.com/dhaber
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
This was a big week in the world of AI, with both OpenAI and Google dropping significant updates. So big that we decided to break things down in a new format with our Consumer partners Bryan Kim and Justine Moore. We discuss the multi-modal companions that have found their voice, but also why not all audio is the same, and why several nuances like speed and personality really matter.
Resources:
OpenAI?s Spring announcement: https://openai.com/index/hello-gpt-4o/
Google I/O announcements: https://blog.google/technology/ai/google-io-2024-100-announcements/
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
Make sure to check out our new AI + a16z feed: https://link.chtbl.com/aiplusa16z
a16z General Partner Anjney Midha joins the podcast to discuss what's happening with hardware for artificial intelligence. Nvidia might have cornered the market on training workloads for now, but he believes there's a big opportunity at the inference layer ? especially for wearable or similar devices that can become a natural part of our everyday interactions.
Here's one small passage that speaks to his larger thesis on where we're heading:
"I think why we're seeing so many developers flock to Ollama is because there is a lot of demand from consumers to interact with language models in private ways. And that means that they're going to have to figure out how to get the models to run locally without ever leaving without ever the user's context, and data leaving the user's device. And that's going to result, I think, in a renaissance of new kinds of chips that are capable of handling massive workloads of inference on device.
"We are yet to see those unlocked, but the good news is that open source models are phenomenal at unlocking efficiency. The open source language model ecosystem is just so ravenous."
More from Anjney:
The Quest for AGI: Q*, Self-Play, and Synthetic Data
Making the Most of Open Source AI
Safety in Numbers: Keeping AI Open
Follow everyone on X:
Check out everything a16z is doing with artificial intelligence here, including articles, projects, and more podcasts.
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
In 2009 Discord cofounder and CEO, Jason Citron, started building tools and infrastructure for games. Fast forward to today and the platform has over 200 million monthly active users.
In this episode, Jason, alongside a16z General Partner Anjney Midha?who merged his company Ubiquity6 with Discord in 2021?shares insights on the nuances of community-driven product development, the shift from gamer to developer, and Discord?s longstanding commitment to platform extensibility.
Now, with Discord's recent release of embeddable apps, what can we expect now that it's easier than ever for developers to build?
Resources:
Find Jason on Twitter: https://twitter.com/jasoncitron
Find Anjney on Twitter: https://twitter.com/AnjneyMidha
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
Human nature fears the unknown, and with the rapid progress of AI, concerns naturally arise. Uncanny robocalls, data breaches, and misinformation floods are among the worries. But what about security in the era of large language models?
In this episode, we hear from security leaders at OpenAI, Anthropic, and Google DeepMind. Matt Knight, Head of Security at OpenAI, Jason Clinton, CISO at Anthropic, and Vijay Bolina, CISO at Google DeepMind, are joined by Joel de la Garza, operating partner at a16z and former chief security officer at Box and Citigroup.
Together, they explore how large language models impact security, including changes in offense and defense strategies, misuse by nation-state actors, prompt engineering, and more. In this changing environment, how do LLMs transform security dynamics? Let's uncover the answers.
Resources:
Find Joel on LinkedIn: https://www.linkedin.com/in/3448827723723234/
Find Vijay Bolina on Twitter: https://twitter.com/vijaybolina
Find Jason Clinton on Twitter: https://twitter.com/JasonDClinton
Find Matt Knight on Twitter: https://twitter.com/embeddedsec
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
In recent years, the AI landscape has seen huge advancements, from the release of Dall-E 2 in April 2022 to the emergence of AI music and video models in early 2024.
While creative tools often steal the spotlight, AlphaFold 2 marked a groundbreaking AI breakthrough in biology in 2021. Since its release, this pioneering tool for predicting protein structures has been utilized by over 1.7 million scientists worldwide, influencing fields ranging from genomics to computational chemistry.
In this episode, DeepMind's VP of Research for Science, Pushmeet Kohli, and a16z General Partner Vijay Pande discuss the transformative potential of AI in scientific exploration. Can AI lead to fundamentally new discoveries in science? Let's find out.
Resources:
Find Pushmeet on Twitter: https://twitter.com/pushmeet
Find Vijay on Twitter: https://twitter.com/vijaypande
Learn more about Google DeepMind: https://deepmind.google
Read DeepMind?s AlphaFold whitepaper: https://deepmind.google/discover/blog/a-glimpse-of-the-next-generation-of-alphafold
Read DeepMind?s AlphaGeometry: https://deepmind.google/discover/blog/alphageometry-an-olympiad-level-ai-system-for-geometry
Read DeepMind?s research on new materials: https://deepmind.google/discover/blog/millions-of-new-materials-discovered-with-deep-learning/
Read DeepMind?s paper on FunSearch, focused on new discoveries in mathematics: https://deepmind.google/discover/blog/funsearch-making-new-discoveries-in-mathematical-sciences-using-large-language-models
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
Over 3,700 companies applied to a16z?s SPEEDRUN. In this episode, we meet the founders pushing the boundaries of what games can be.
From the fusion of traditional gaming elements with modern tech-twists, a16z General Partner Andrew Chen and Partner Josh Lu discuss the challenges and wins of creating games that are not only fun but also integrate seamlessly into the digital age, from AI-twins to games that ?move at the speed of culture?.
Whether you?re a developer, an enthusiast, or just curious about the future of interactive entertainment, this episode provides a glimpse into how today's creators use creativity and technology to captivate.
If you're passionate about shaping the future of gaming, consider applying for SPEEDRUN 3.0 at a16z.com/speedrun3.
Resources:
Submit your SPEEDRUN 3.0 application: https://a16z.com/speedrun-la-2024
Find Andrew on Twitter: https://twitter.com/andrewchen
Find Josh on Twitter: https://twitter.com/JoshLu
Learn more about Avi and Magic Circle: https://twitter.com/aviromanoff
Learn more about Lil Snack: https://www.lilsnack.co
Learn more about Neon Wild: https://www.neonwild.com
Learn more about Open Souls: https://www.opensouls.studio
Learn more about Altera: https://altera.al
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
Senator Todd Young (R-IN) speaks with a16z General Partner Martin Casado about the importance of open innovation and American leadership in AI, and why we need to support AI research at all levels ? from the classroom to the war room.
In this episode, we distinguish science fiction from science reality in the ever-evolving AI landscape.
Resources:
Find Senator Todd Young on Twitter: https://twitter.com/toddyoungin
Find Martin Casado on Twitter: https://twitter.com/martin_casado
Watch the American Dynamism stage talks on YouTube: https://bit.ly/3IqWn1W
To learn more about the American Dynamism Summit, visit our website: a16z.com/ad-summit
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
The gaming industry stands as a pioneer of cutting-edge technologies, ushering in innovations like GPUs, virtual and augmented reality, physics engines, and immersive multiplayer experiences.
In this episode, a16z cofounder Marc Andreessen and Andrew Chen, General Partner at a16z Games, dig into why a16z was compelled to establish a dedicated games fund. They explore the origins of tech pessimism, effective engagement with government in tech, its significance for the gaming community, the ongoing AI revolution, and even what Marc himself would build today if he didn't have his hands full.
Recorded as part of a16z's extensive games fund accelerator, SPEEDRUN, this session offers valuable insights for founders and innovators at the intersection of games and technology.
If you're passionate about shaping the future of gaming, consider applying for SPEEDRUN 3.0 at a16z.com/speedrun3.
Resources:
Find Marc on Twitter: https://twitter.com/pmarca
Find Andrew on Twitter: https://twitter.com/andrewchen
Submit your SPEEDRUN 3.0 application: https://a16z.com/speedrun-la-2024
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
From air-defining radar and electronic systems that helped the Allies win World War II, the origins of Silicon Valley are deeply rooted in government and defense.
In today's episode, we get the chance to revisit that relationship with the United States Deputy Secretary of Defense, Kathleen Hicks.
Deputy Secretary Hicks has spent decades of her career focused on defense policy and in her keynote address from a16z's second annual American Dynamism Summit in Washington, D.C., you'll get an inside look into the priorities of the DoD and how it views its past, present, and future.
In the second half of the episode, you?ll hear highlights from Deputy Secretary Hicks' fireside chat with Wall Street Journal?s National Security Editor, Sharon Weinberger, where they dive into the numerous issues facing our country today, from Ukraine to the use of AI on the battlefield.
Resources:
Find Deputy Secretary Hicks on Twitter: https://twitter.com/depsecdef
Find Sharon on Twitter: https://twitter.com/weinbergersa
To learn more about the American Dynamism Summit: www.a16z.com/ad-summit
Visit the full playlist of American Dynamism Summit videos on YouTube: https://bit.ly/3IqWn1W
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.