Top 100 most popular podcasts
How do the amino acids in a soy patty and a beef patty compare once they reach your blood?
In a trial he helped design, Dr. David Church matched a 4-ounce beef patty against a soy-based burger. He had to double the soy to roughly match the single beef patty in essential amino acids. The blood amino acid levels shocked him.
David joins me at Protein Summit 3.0 to explain what happened.
He also tells me why muscle protein breakdown is so much harder to measure than synthesis, and shares insights from his 21-day testosterone study, where the men on testosterone lost all of their weight as fat while the placebo group lost about half of theirs as fat-free mass.
Thank you to our sponsors:
- Cozy Earth: 20% off home and sleepwear at cozyearth.com with code DOCTORLYON
- Timeline: an additional 20% off at timeline.com/lyon
- Bon Charge: 30% off sitewide in their Black Friday sale with code DOCTORLYON30
Find Dr. David Church at:
- UAMS profile: https://uams-triprofiles.uams.edu/profiles/profile/5838748
- Instagram: https://www.instagram.com/dr.myohead
- LinkedIn: https://www.linkedin.com/in/david-church-6b0662280
- X (Twitter): https://x.com/DrMyohead
Find Dr. Gabrielle Lyon at:
- Instagram: https://www.instagram.com/drgabriellelyon/
- TikTok: https://www.tiktok.com/@drgabriellelyon
- Facebook: https://facebook.com/doctorgabriellelyon
- YouTube: https://youtube.com/@DrGabrielleLyon
- X (Twitter): https://x.com/drgabriellelyon
- Apply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/
- Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.page
Chapters:
0:00 – Dr. David Church on the Nandrolone Aging Study in Mice
3:17 – What Testosterone Changed in Men During a 21-Day Energy Deficit
6:14 – Androgens, Hormones and What We Still Do Not Know in Women
9:43 – Stable Isotope Tracers Explained With Legos
10:56 – Why Muscle Protein Breakdown Is So Hard to Measure
13:23 – How Testosterone May Recycle Amino Acids Inside the Muscle Cell
16:01 – Net Protein Balance, Burns and Whole-Body Protein
18:38 – Obesity, Anabolic Resistance and the 1.2 g/kg Protein Target
24:38 – Testosterone and Protein as Complementary Levers
26:15 – Nandrolone, Satellite Cells and Muscle Memory
32:50 – The Soy Burger vs. Beef Patty Trial
40:18 – Plant Protein, Low Appetite and Essential Amino Acid Supplements
41:16 – GLP-1 Responders and Why Dr. Lyon Uses Essential Amino Acids
47:49 – Are Essential Amino Acids Requirements Higher Than We Thought?
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Protein has become a numbers game, and the numbers leave out the essential amino acids your muscle, brain and metabolism depend on. Protein is how you get them, and its quality may change how well you age.
In this episode, Dr. Gabrielle Lyon brings together some of her favorite moments with Dr. Don Layman, Dr. Heather Leidy and Dr. Jess Gwin to break down the essential amino acid requirement, cut through the confusion on protein quality (what a protein label leaves out, plant vs. animal sources, branched-chain amino acids, and leucine), and explain what the research says about essential amino acids in brain function, mood, sleep, energy deficit, and anabolic resistance as we age.
If you have ever wondered what your protein label isn't telling you, or why half an ounce of nuts and an ounce of lean beef count as the same serving, this conversation offers a clear, practical look at what the science says.
Thank you to our sponsors:
- BodyHealth: 20% off your first order at bodyhealth.com with code LION20
- Tushy: 10% off your first bidet order at hellotushy.com with code DOCTORLION
Find Dr. Don Layman, Dr. Heather Leidy and Dr. Jess Gwin at:
- Dr. Heather Leidy: https://nutrition.utexas.edu/directory/heather-leidy/
- Dr. Don Layman: https://x.com/donlayman
- Dr. Jess Gwin: https://www.researchgate.net/profile/Jess-Gwin
Find Dr. Gabrielle Lyon at:
- Instagram: https://www.instagram.com/drgabriellelyon/
- TikTok: @drgabriellelyon
- Facebook: facebook.com/doctorgabriellelyon
- YouTube: youtube.com/@DrGabrielleLyon
- X (Twitter): x.com/drgabriellelyon
- Apply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/
- Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.page
Chapters:
0:00 – Why the Requirement Is Essential Amino Acids, From Muscle to Mood and Sleep
3:24 – Dr. Jess Gwin on Protein Quality and Why the Dietary Guidelines Miss It
5:36 – What a Protein Label Does and Doesn't Tell You
6:50 – Nuts vs. Lean Beef and the Cost of Going Plant-Based
9:35 – Dr. Don Layman on Branched-Chain Amino Acids, Leucine and mTOR
11:19 – How Much Protein Reaches the Leucine Threshold
14:00 – Dr. Jess Gwin on Essential Amino Acids Under Energy Deficit and Stress
16:36 – Dosing, Aging and Anabolic Resistance
19:26 – Whole Foods vs. Amino Acid Powders as Tools
21:29 – Dr. Lyon's First-Meal Routine
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Eating before bed: harmful or helpful? Dr. Mike Ormsbee breaks down protein before bed, casein vs. whey, fat metabolism, sleep, and resistance training for postmenopausal women.
Late-night eating comes with many rules of thumb, and most people follow them without knowing what the research shows. Dr. Mike Ormsbee, a researcher at Florida State University, has spent years measuring how protein before bed affects metabolic rate, overnight fat burning, sleep, and recovery. If you lift, want to keep muscle as you age, or have been told to stop eating after dinner, his view on casein vs. whey and bedtime snacks may change what you keep in the kitchen.
Thank you to our sponsors:
- BodyHealth: 20% off at https://bodyhealth.com with code LYON20
- One Skin: 15% off with code Doctor Lion at oneskin.com
- Ladder app: ladder.fit/doctorlion, free 7-day trial, no credit card, $10 off the first month
Find Dr. Mike Ormsbee at:
- Visit www.mikeormsbee.com/lyon
- Instagram: https://www.instagram.com/mikeormsbee/?hl=en
- Course, Changing Body Composition Through Diet and Exercise (The Great Courses): https://shop.thegreatcourses.com/changing-body-composition-through-diet-and-exercise
Find Dr. Gabrielle Lyon at:
- Instagram: https://www.instagram.com/drgabriellelyon/
- TikTok: @drgabriellelyon
- Facebook: facebook.com/doctorgabriellelyon
- YouTube: youtube.com/@DrGabrielleLyon
- X (Twitter): x.com/drgabriellelyon
- Apply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/
- Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.page
Chapters:
0:00 – The Eating-Before-Bed Debate and How Pre-Sleep Feeding Is Defined
5:00 – Metabolic Rate, Belly-Fat Probes and Casein vs. Whey
9:14 – Exercise as Our "Metabolic Apology" for Poor Diet and Poor Sleep
15:07 – Resistance Training and Fat Metabolism
21:58 – Inside the Five-Year NIH Study: Lifting vs. Cardio After Menopause
31:59 – Growth Hormone, Fed vs. Fasted Training and Why Obesity Slows the Response
36:29 – Protecting Muscle During Rapid Weight Loss and How Much Lifting Is Enough
43:09 – What the Postmenopausal Study Is Showing So Far
50:00 – Sleep, Evening Exercise and the Hungry-at-Night Protein Snack
55:47 – Does Excess Protein Turn to Fat? Older Adults, Calories and Timing
1:02:25 – Collagen, Creatine and Ketones: What He Takes and Skips
1:11:15 – Casein vs. Whey, Future Research and His Best Advice for Postmenopausal Women
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Childhood and adolescence provide a one-time biological opportunity: our kids' bodies are primed to grow, build tissue, and develop cognitive capacity. But to do that, they need the right raw materials.
In this video, we break down why restricting nutrient-dense foods in growing children puts their development at risk. We explore the critical role of highly bioavailable nutrients like heme iron and vitamin B12, how nutrient status directly impacts academic performance and attention, and why building muscle and metabolic reserve early protects your health decades later.
Don't wait until your children are 40 and struggling with their health to teach them what strong looks like.
Thank you to our sponsor:
Rula: https://www.rula.com/drlyon
Chapters:
00:00 - Introduction: Why We Must Start in Childhood
01:14 - Kids Are Not "Little Adults": Growth vs. Maintenance
02:25 - Puberty & Protein Metabolism: The Role of Leucine
03:50 - How Much Protein Do Kids Actually Need? (RDA vs. Modern Data)
06:10 - Protein Requirements for Active and Athletic Youth
08:35 - Upgrading the Typical Kid Diet: High-Quality Protein Sources
11:47 - Bone Accrual & Debunking the Youth Strength Training Myth
14:10 - Neurological Strength: Why Kids Get Stronger Without Bulking Up
17:15 - Resistance Training for Girls: Hormones, Strength & Busting the "Bulk" Fear
20:50 - Critical Micronutrients for Brain & Body: Iron and B12
22:45 - Building Lifelong Biological Reserve: Raising Capable Humans
Explore More from Dr. Gabrielle Lyon
Weekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/
Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient
Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon
TikTok: https://tiktok.com/@drgabriellelyon
X (Twitter): https://x.com/drgabriellelyon
Facebook: https://www.facebook.com/doctorgabriellelyon
Studies mentioned in the podcast:
https://pubmed.ncbi.nlm.nih.gov/42752819/
https://pubmed.ncbi.nlm.nih.gov/35020179/
https://pubmed.ncbi.nlm.nih.gov/35011099/
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
What you choose to eat is the single most important decision you make every day—impacting your metabolic health, your family, the economy, and the future of our food supply.
In this episode, world-renowned cardiologist and nutrition expert Dr. Dariush Mozaffarian breaks down the "Food is Medicine" movement, cuts through dietary confusion (fats vs. carbs, food label marketing, and ultra-processed ingredients), and reveals how public demand, science, and policy can repair a broken food system. If you have ever felt overwhelmed in the grocery aisle or wondered how to separate real nutrition science from industry marketing, this conversation provides a clear, practical roadmap.
Thank you to our sponsors:
BodyHealth: 20% off at https://bodyhealth.com with code LYON20
Timeline: 20% off at http://www.timeline.com/lyon
Wildgrain: $40 off first box + free croissants for life at http://www.wildgrain.com/drlyon40 with code LYON40
Food is Medicine by Dr. Dariush Mozaffarian: https://us.macmillan.com/books/9781250394286/foodismedicine/
Chapters:
00:00 - The Reality of Our Current Food System
05:12 - Carbs vs. Fats: Breaking Down the Science
18:40 - How to Read a Food Label Like an Expert
32:15 - Ultra-Processed Foods & Why Real Food Spoils
48:30 - The History of Food Policy: From the Green Revolution to Today
01:05:10 - The Economics of Chronic Illness
01:21:40 - The Crucible: Science, Government, and Consumer Power
01:31:54 - "Food is Medicine" & Dr. Mozaffarian's Ultimate Message
Explore More from Dr. Gabrielle Lyon
Weekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patientConnect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyonTikTok: https://tiktok.com/@drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyon/If you found this episode valuable, share it with someone who would benefit from it. Disclaimers: This episode includes paid sponsorships. The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Protein is in everything right now: coffee, chips, cookies, bars. But despite the massive marketing hype, the world’s leading scientists are still debating fundamental questions about how much protein we actually need and how the body uses it. Fresh off the Protein Summit 3.0 at Texas A&M, Dr. Gabrielle Lyon breaks down what top researchers agreed on, why treating protein as a single number is a major mistake, and how to stop falling for "high-protein" health halos in the grocery store.
Find Dr. Gabrielle Lyon at:
Protein is in everything right now: coffee, chips, cookies, bars. But despite the massive marketing hype, the world’s leading scientists are still debating fundamental questions about how much protein we actually need and how the body uses it. Fresh off the Protein Summit 3.0 at Texas A&M, Dr. Gabrielle Lyon breaks down what top researchers agreed on, why treating protein as a single number is a major mistake, and how to stop falling for "high-protein" health halos in the grocery store.
Explore More from Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: tiktok.com/@drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX: x.com/drgabriellelyonApply to become a patient: https://drgabriellelyon.com/new-patient-inquiry/Weekly newsletter: https://institute-for-muscle-centric-medicine.ck.pageOrder my new book: https://www.amazon.com/exec/obidos/ASIN/1668085623Chapters:
00:00 - Introduction & Protein Summit
02:30 - Amino Acids Beyond Muscle
05:55 - Minimum vs. Optimal Protein
08:13 - Lab Studies vs. Real Life
10:33 - Context & Individual Needs
12:04 - The Fortification Trap
14:41 - The Whole Food Matrix
16:18 - Research Funding & Transparency
18:00 - The Future of Protein
Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
In this episode, board-certified anesthesiologist, researcher, and former Real Housewives of Dallas star Dr. Tiffany Moon pulls back the curtain on modern medicine, surgical pain management, and the reality of navigating elite academia. From addressing widespread public fears around clinical fentanyl use to detailing why she was branded an "embarrassment" by academic peers for appearing on reality television, Dr. Moon speaks candidly about breaking stereotypes, the gender pay gap in healthcare, and using a massive public platform to advocate for science and mentorship.
What You'll Learn In This Episode:
The Clinical Truth About Fentanyl: Why it is the standard of care for 90% of surgeries, and why post-op patients shouldn't fear becoming addicted.The Reality TV Fallout: How appearing on The Real Housewives led to institutional blowback—and why she’d do it again.Leveraging Fame for Science: Turning pop culture visibility into serious advocacy for mentorship, healthcare equity, and closing the gender pay gap.Shattering Stereotypes: Moving past appearances to run clinical trials, publish randomized controlled studies, and teach the next generation of physicians.Thank you to our sponsors:
Cozy Earth: cozyearth.com Use code DRLYON for 20% offOur Place: fromourplace.com Use code DRLYON for 10% offBranch Basics: branchbasics.com Use code DRLYON for 15% off Premium Starter KitExplore More from Dr. Gabrielle Lyon
Weekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patientFind Dr. Tiffany Moon at:
Instagram: instagram.com/tiffanymoonmd (@tiffanymoonmd)TikTok: tiktok.com/@tiffanymoonmd (@tiffanymoonmd)YouTube: youtube.com/@TiffanyMoonMDOfficial (@TiffanyMoonMDOfficial)Website: tiffanymoonmd.comFacebook: facebook.com/tiffanymoonmd (@tiffanymoonmd)X (Twitter): x.com/TiffanyMoonMD (@TiffanyMoonMD)Connect with Dr. Gabrielle Lyon:
Instagram: / drgabriellelyonTikTok: / drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: / doctorgabriellelyonChapters
00:00 – The Truth About Fentanyl in Surgery
01:18 – Breaking Stereotypes in Academic Medicine
12:00 – Pain Protocols, Anesthesia Safety & Clinical Trials
25:00 – Reality TV, Academic Backlash & Healthcare Equity
40:00 – Career Reinvention & Overcoming Physician Burnout
1:00:00 – Why Preventive Medicine Is the Future
1:08:39 – Longevity Medicine, GLP-1s & Muscle Health
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships. The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Can you tell someone's testosterone or estrogen levels just by looking at their face? Is "jawmaxxing" actually backed by science? In this video, we dive deep into the real science of hormones, physical attraction, and evolutionary biology.
We debunk popular myths around high testosterone, facial masculinity, and ovulation preferences, revealing what the research actually shows about human mate selection. Discover why facial structure isn't a hormone panel, how estrogen impacts skin and collagen as women age, and why physical strength accounts for 70% of perceived bodily attractiveness.
If you want to understand how hormones shape our development—and why muscle is the single most modifiable signal of health and longevity—this episode is for you.
Find Dr. Gabrielle Lyon at:
- Instagram: https://www.instagram.com/drgabriellelyon/
- TikTok: tiktok.com/@drgabriellelyon
- Facebook: facebook.com/doctorgabriellelyon
- YouTube: youtube.com/@DrGabrielleLyon
- X: x.com/drgabriellelyon
- Apply to become a patient: https://drgabriellelyon.com/new-patient-inquiry/
- Weekly newsletter: https://institute-for-muscle-centric-medicine.ck.page
- Order my new book: https://www.amazon.com/exec/obidos/ASIN/1668085623
Chapters:
00:00 What role do hormones play in the traits we find attractive?
00:46 High vs. low testosterone: does it change who we pick?
01:44 The ovulation story: do women seek out masculine men?
03:19 Two questions: can you see hormones, and what's modifiable?
04:12 What testosterone and estrogen build during development
05:23 Does winning raise testosterone? What a masculine face tells you
06:26 Selection, training and genes: why muscle isn't just testosterone
07:54 Are women attracted to testosterone? What the longitudinal studies show
09:29 Face vs. strength: what predicts mating success
10:08 The 70% finding: strength and bodily attractiveness
11:44 Why strength is a hard-to-fake health signal
13:41 Can you see estrogen? Facial ratings and why more isn't better
14:41 Culture moves beauty standards, and estrogen shows up in skin
16:08 Estrogen therapy and skin: what it can and can't do
16:36 Can you see hormones? Muscle is the system you can see and change
Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
When you have musculoskeletal pain, the natural instinct is to try and treat it directly. But the cause of that pain often starts somewhere else in the body.
I learned that from this week's guest, Dr. JJ Thomas, who is my physical therapist and good friend. She was my patient first, and now we are each other's patients. She has practiced physical therapy for more than 25 years and has worked with the Philadelphia 76ers, the Philadelphia Eagles, and athletes from the UFC and US Olympic programs.
What you'll learn in this episode:
Why a chronic tendon injury can come right back, even after eccentric loading or PRPWhether a frozen shoulder in menopause is a hormone problem, and one of the first movements Dr. Thomas checksWhy she works lying on her stomach, and the 10-minute band routine she wrote for an eight-hour desk dayWhy sitting up taller won't fix your posture, and what poor posture tells her about your bodyWhy she gives patients shoulder blade exercises for their pelvic floorHow much a standard squat does for your posterior chain, and the position she wants you in more oftenWhy she believes “overuse” injuries are often underuse injuries, and how that changes the way she treats shin splintsWhy needling a clinician's quad and adductors normalized his neck rotationWhat her blood work showed after years of hard training, and the nutrition change she calls her “game changer”Thank you to our sponsors:
• Manukora - Get 31% off at https://www.manukora.com/drlyon
• Timeline - up to 20% off when you subscribe and save at https://www.timeline.com/lyon
• Bon Charge - Use code DRLYON for 15% off at https://www.boncharge.com
Explore More from Dr. Gabrielle Lyon
Weekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/
Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patie...
Find Dr. JJ Thomas at:
• YouTube: https://www.youtube.com/@drjjthomas
• Website: https://primalphysicaltherapy.com/
• Instagram: https://www.instagram.com/drjjphysicaltherapist/
Connect with Dr. Gabrielle Lyon:
• Instagram: https://www.instagram.com/drgabriellelyon/
• TikTok: https://www.tiktok.com/@drgabriellelyon
• Facebook: http://facebook.com/doctorgabriellelyon
• X: http://x.com/drgabriellelyon
• Apply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/
• Weekly newsletter – https://institute-for-muscle-centric-medicine.ck.page
Chapters
00:00 – Posture Myths & Why Sitting Up Straight Fails
02:18 – Treating Root Causes vs. Bandaging Pain
06:48 – The Hazards of Sitting & Reframing Movement as Health
13:39 – The 7 Primal Movement Patterns Every Body Needs
25:28 – Scapular Stability, Pelvic Health, and Primal Movements
39:12 – Fixing Glute Amnesia & Activating the Posterior Chain
51:57 – Why "Overuse" Injuries Are Really Underuse Problems
58:34 – Dry Needling & System-Based Movement Resets
1:13:53 – Dialing in Hormones, Protein, and Metabolic Health
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Will I get too bulky?" No. "Is it too late?" Also no. Here's the context: during the menopause transition, women lose lean mass, gain fat, and their muscle becomes harder to build — the same workout and the same protein meal produce less than they did at 30. For years the only conversation has been hormone therapy, yes or no, as if that were the fix. In Part 2 of her menopause series, Dr. Gabrielle Lyon looks at what the evidence actually says builds muscle back.
In this episode:
-Postmenopausal women can build muscle and strength at any age (Frontiers in Endocrinology)
- Up to 8 lbs of skeletal muscle in 12 weeks (J Nutr Health Aging RCT)
- Anabolic resistance: why the same workout and the same meal produce less after menopause
- "I was wrong": hormone therapy vs. lifting, and the conversations with Dr. Donald Layman
- HRT alone and lean mass: a 0.06 kg difference across 12 trials
- Estradiol plus training: bigger quad and fat-free mass gains, maintained at 12 months
- Lift first — the practical translation while the HRT evidence evolves
- Why protein matters more after menopause, and why 60 g spread thin isn't enough
- The RDA (0.8 g/kg) isn't enough to protect bone; ESCEO's 1–1.2 g/kg floor
- Doubling protein to 1.6 g/kg: more fat lost, more lean mass kept
- The 6-step Forever Strong menopause protocol
Sponsor
David Protein — 28 g of protein, 150 calories, zero sugar → davidprotein.com/drlyon, subscribe to save 10% on every order
Find Dr. Gabrielle Lyon at:
- Instagram: https://www.instagram.com/drgabriellelyon/
- TikTok: tiktok.com/@drgabriellelyon
- Facebook: facebook.com/doctorgabriellelyon
- Apply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/
- Weekly newsletter – https://institute-for-muscle-centric-medicine.ck.page
Chapters:
00:00 Will I get too bulky? Is it too late? Both answers are no
01:09 Postmenopausal women gained up to 8 lbs of muscle in 12 weeks
02:24 Anabolic resistance: more volume, more intensity, more protein
03:34 Hormone therapy or lifting? "I was wrong"
05:16 HRT alone and lean mass: 0.06 kg across 12 trials
06:16 Estradiol amplifies training — it doesn't replace it
07:22 Lift first: what to do while the evidence evolves
10:21 Why protein matters more after menopause (and why 60 g isn't enough)
11:16 The RDA won't protect your bones: the 1–1.2 g/kg floor
12:16 Doubling protein: more fat lost, more lean mass kept
13:22 The Forever Strong protocol, step 1: train 2–3 days a week
14:15 Steps 2–3: 30–50 g protein at first and last meal, impact and loading
15:13 Steps 4–6: hormone therapy with training, body composition, blood work
16:07 You're not alone: the Menopause Challenge
Disclaimer: This podcast is for general informational purposes only and does not constitute medical advice or create a doctor–patient relationship. It is not a substitute for professional medical advice, diagnosis, or treatment. Do not disregard or delay seeking medical advice because of something you heard here.
Most patients are told one thing before surgery: stop all supplements. Duke surgeon Dr. Rebecca Knackstedt says that blanket advice can do harm, and that what you do in the days before surgery changes how you heal.
Dr. Knackstedt is a plastic and reconstructive microsurgeon on faculty at Duke, an MD-PhD researcher and a certified functional medicine provider whose research focuses on surgical prehabilitation: preparing the body, mind, and home before surgery, the way we already do with rehab.
In today’s episode, we discuss:
• What prehab looks like for any operation
• The labs she checks
• Which supplements to keep and which to stop (omega-3s do not increase bleeding)
• Hormones after breast cancer
• Why mammograms still beat thermography
• What chemo does to metabolism
• The questions to ask your oncologist before a treatment decision
• How much protein to eat (no standard exists, and the average woman gets 60 to 70 grams a day, well short of the 100-gram floor)
• Why surgery is catabolic and muscle is your reserve
• Carbohydrate loading before the fasting cutoff and why it can reduce pain
• The five-day window that lowered complications and even mortality in head and neck cancer patients
• Why early walking replaced routine bed rest
Connect with Dr. Knackstedt
Instagram → https://www.instagram.com/surgical_recovery/
Website → https://www.clararecovery.com/
Sponsors
• Perfect Amino by BodyHealth, https://bit.ly/4wZgg6N, code LYON20 for 20% off your first order
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Find Dr. Gabrielle Lyon at:
• Instagram: https://www.instagram.com/drgabriellelyon/
• TikTok: tiktok.com/@drgabriellelyon
• Facebook: http://facebook.com/doctorgabriellelyon
• X: http://x.com/drgabriellelyon
• Apply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/
• Weekly newsletter – https://institute-for-muscle-centric-medicine.ck.page
Chapters:
00:00 Prehab saves lives and money. So why isn't it standard of care?
01:05 Meet Dr. Rebecca Knackstedt: Duke microsurgeon and functional medicine provider
05:35 The patient who changed everything, and why good surgery isn't enough
08:34 What prehab is, and the exercises to do before any surgery
12:14 Hormones after breast cancer, rising rates in young women, and real risk factors
18:42 Chemo, metabolic syndrome and why body composition matters
23:13 The end of bed rest, and the labs that matter before surgery
27:04 Mammograms vs. thermography, and absolute vs. relative risk
34:12 Protein before surgery: 2 g/kg, track 3 days, never under 100 g
38:43 Supplements to take, and why "stop all supplements" is wrong
44:40 Preparing the mind: anxiety, sleep, anesthesia depression, expectations
51:21 Red light, saunas, hyperbaric oxygen, wound vacs, scars and pain control
1:04:59 Surgery is catabolic: muscle as your glucose reserve
1:07:34 Carb loading, the 5-day window, probiotics and the surgery go-bag
1:14:15 Why prehab isn't standard of care yet, and why she's hopeful
Disclaimer: This podcast is for general informational purposes only and does not constitute medical advice or create a doctor–patient relationship. It is not a substitute for professional medical advice, diagnosis, or treatment. Do not disregard or delay seeking medical advice because of something you heard here.
Menopause is changing your body, but the part nobody talks about isn't hot flashes. It's muscle. Women lose lean mass fastest in perimenopause, the loss probably starts closer to 35, and no pill, patch or injection fixes it.
In this solocast, Dr. Gabrielle Lyon explains what estrogen, testosterone and FSH actually do to your metabolism, why a 50-year-old body can still build muscle, and the training and protein protocol to start now.
Join the Menopause Challenge →
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[Use Code 25OFF through Sept 27]
Thank you to our sponsors:
- Rula, therapy covered by insurance → rula.com/drlyon
Find Dr. Gabrielle Lyon at:
- Instagram: https://www.instagram.com/drgabriellelyon/
- TikTok: @drgabriellelyon
- Facebook: facebook.com/doctorgabriellelyon
- YouTube: youtube.com/@DrGabrielleLyon
- X (Twitter): x.com/drgabriellelyon
- Apply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/
- Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.page
- Pre-order my new book - https://www.amazon.com/exec/obidos/ASIN/1668085623
Chapters:
00:00 Menopause is changing your body — but it doesn't have to change your life
00:59 The suitcase story: today is about muscle, not hot flashes
01:47 Hormone therapy, yes or no? Why that's the wrong first question
03:36 What menopause is, when it arrives, and 40% of your life after it
04:37 When lean mass really starts to fall — and why testing misses it
06:46 Testosterone vs. estrogen: no two women go through it the same way
08:40 Anabolic resistance: why the muscle-building switch gets sticky
10:31 Estrogen, joints and injury risk (Dr. Jocelyn Wittstein)
13:27 Less muscle, nowhere to put carbs: the lean prediabetic patient
14:19 Falls, fractures, heart disease, and muscle as an early bone signal
16:14 Visceral fat, energy expenditure, fat oxidation and FSH
18:02 Test your blood — and pull the levers you control
19:00 The starting protocol: 2–3 days a week and the movements to keep
20:30 Menopause changes your body, not your life — the Menopause Challenge
Mentioned
- Dr. Jocelyn Wittstein on estrogen, joints and injury risk → https://youtu.be/ILyzNTjZTGI
- Juliet & Dr. Kelly Starrett on floor sitting and mobility → https://youtu.be/QOjzh-711Q0
- SWAN (Study of Women's Health Across the Nation)
- The Lancet Diabetes & Endocrinology review on lean mass and chronic disease
- ESCEO guidance on muscle and bone
Disclaimers: This episode includes paid sponsorships. The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Your testosterone number matters at every age, but most men never learn what theirs should be. Mayo Clinic urologist Dr. Tobias Kohler explains why ~500 is the target, why 1,000 is already running hot, what 2,000+ does to the heart, and why a randomized trial found lifting without steroids beat steroids without lifting. Plus: the blood test that catches heart risk your cholesterol panel misses.
Dr. Kohler returns for his second appearance (his first, on erections, testosterone and muscle mass, is one of the most-watched episodes in the show's history). This time: why men's longevity is roughly 50 years behind women's; the Princeton IV consensus he co-chaired, which treats ED as one of the strongest predictors of a future heart attack and points young men toward a coronary calcium scan; the 0–12 ceramide blood test that changes with your behavior; how to get a testosterone baseline that actually means something; what redlining to 2,000–3,000 does to the heart, the set point and the skin; Peyronie's disease, Viagra vs. Cialis, the pills-to-implant ladder, sexual rehab after prostate surgery, and a patient who got stronger with zero testosterone.
About Dr. Tobias Kohler
Tobias S. Kohler, MD, MPH, is Professor of Urology at Mayo Clinic, a fellowship-trained andrologist with 25+ years of clinical and surgical experience and 250+ peer-reviewed publications. He co-chaired the Princeton IV Consensus Guidelines on ED and cardiovascular disease, co-founded the EROS penile implant registry, and co-edited Contemporary Treatment of Erectile Dysfunction (2nd ed.).
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📺 Watch the “Dr. Gabrielle Lyon Show” every Tuesday at 9AM EST:
YouTube: https://bit.ly/4boCFC3
Spotify: https://bit.ly/4cWTbLG
📱 Connect with Dr. Gabrielle Lyon:
Instagram: https://bit.ly/4uk9adc
TikTok: https://bit.ly/3OFK3kJ
X.com: https://bit.ly/4l3YlaX
Facebook: https://bit.ly/3MBrJso
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Website: https://bit.ly/3NdV2kT
Books: https://bit.ly/4r6ugZK
Newsletter: https://bit.ly/402QCAj
⏰Chapters
00:00 Men are dying earlier than women the penis is the check-engine light
03:26 Boys stop seeing doctors for 20 years the case for an Office of Men's Health
10:57 Princeton IV: ED predicts heart attacks, calcium scans, and Cialis
12:44 The ceramide blood test your cholesterol panel can't replace
20:37 Cardiac risk calculators, statins, and what your LDL should be
25:38 GLP-1s, fertility, and "what's the risk of doing nothing?"
29:05 Testosterone: the ~500 target, why 1,000 runs hot, what 2,000+ does to the heart
31:44 Check your testosterone at 25 and why steroids won't make you a pro
36:57 Tolerance and the new set point redlined men can't escape
38:13 The 1980s trial: lifting without steroids beat steroids without lifting
42:06 Steroid cocktails, arrhythmias, irreversible side effects, and the sarcopenia trade-off
53:04 Peyronie's disease and Viagra vs. Cialis
57:32 Penile implants: the knee-replacement analogy and the pills-to-surgery ladder
1:02:27 Sexual rehab after prostatectomy and the questions to ask before cancer treatment
1:07:55 Closing: be proactive and the patient who got stronger with zero testosterone
Disclaimer: This podcast is for general informational purposes only and does not constitute medical advice or create a doctor–patient relationship. It is not a substitute for professional medical advice, diagnosis, or treatment. Do not disregard or delay seeking medical advice because of something you heard here.
You say "steroids" and picture a baseball scandal, a jacked guy, a bad spray tan. But cortisol is a steroid. Estrogen is a steroid. The cream you put on poison ivy is a steroid. The word covering all of them is also covering testosterone therapy for women, and that collision is quietly costing women muscle and bone they don't have to lose.
In this solo episode, prompted by a magazine interview on steroid use in women, Dr. Gabrielle Lyon breaks down what these molecules actually are, what they do inside a cell, and why the line between medicine and misuse has nothing to do with the word "steroid."
Study and References:
The Effects of Supraphysiologic Doses of Testosterone on Muscle Size and Strength in Normal Men (Bhasin et al., NEJM 1996) - https://pubmed.ncbi.nlm.nih.gov/8637535/
Testosterone Enhances Estradiol's Effects on Postmenopausal Bone Density and Sexuality (Davis et al., 1995) - https://pubmed.ncbi.nlm.nih.gov/7616872/
Global Consensus Position Statement on the Use of Testosterone Therapy for Women (2019) - https://pubmed.ncbi.nlm.nih.gov/31498...
ISSWSH Clinical Practice Guideline for the Use of Systemic Testosterone for HSDD in Women (2021) - https://pubmed.ncbi.nlm.nih.gov/33814...
The Global Epidemiology of Anabolic-Androgenic Steroid Use: A Meta-Analysis (Sagoe et al., 2014) - https://pubmed.ncbi.nlm.nih.gov/24582...
What Is the Prevalence of Anabolic-Androgenic Steroid Use Among Women? A Systematic Review (Piatkowski et al., Addiction, 2024) - https://onlinelibrary.wiley.com/doi/1... "
The Compounds for Females Are Really Commonly Faked!": Women's Challenges in Anabolic Steroid Acquisition (Piatkowski et al., Drug and Alcohol Review, 2024) - https://onlinelibrary.wiley.com/doi/1...
Explore More from Dr. Gabrielle Lyon:
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon's clinical team https://drgabriellelyon.com/new-patie...📱 Connect with Dr. Gabrielle Lyon:
Instagram: https://bit.ly/4uk9adc
TikTok: https://bit.ly/3OFK3kJ
X.com: https://bit.ly/4l3YlaX
Facebook: https://bit.ly/3MBrJso
LinkedIn: https://bit.ly/3N1nrdL
Website: https://bit.ly/3NdV2kT
Books: https://bit.ly/4r6ugZK
Newsletter: https://bit.ly/402QCAj
📺 Watch the “Dr. Gabrielle Lyon Show” every Tuesday at 9AM EST:
YouTube: https://bit.ly/4boCFC3
Spotify: https://bit.ly/4cWTbLG
⏰ Chapters:
00:00 - Beginning
01:25 - Introduction: The Sister Who Says "Oh My Gosh, You're Taking Steroids" Why Medicine Needs a Shared Vocabulary
03:43 - What a Steroid Actually Is: Four Rings of Carbon
04:49 - Anabolic vs. Androgenic: Same Receptor, Different Effects
06:16 - A Brief History: From Wasting Disease to the Weight Room
08:59 - Restoring vs. Exceeding: Why the Range Is the Whole Game
11:38 - The Davis Trial: Testosterone, Bone Density, and Lean Mass
13:38 - Oral Compounds, the Liver, and Why Conversion Matters
14:20 - What Gets Sold Isn't What's Labeled: The Australian Drug-Checking Data
15:31 - The 1.6% vs. 4% Myth: Reading the Prevalence Data Correctly
18:33 - Why GLP-1s Are Pushing Women Toward Androgens
20:26 - Permanent Effects: Voice Changes and What the Literature Shows
21:33 - The Four Questions to Ask Before Any Androgen Conversation
24:25 - Closing: Entering the Sarcopenia Era
‼️ Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Most people assume becoming a parent is an emotional change, but a measurable part of it is hormonal, and it happens in fathers too. I sat down with Aldrich Chan, Psy.D., to talk about what changes in the brain, why the split we draw between mind and body does not hold up, and what decides whether stress reads as manageable or overwhelming when the hormones are identical either way.
Want ad-free episodes? Subscribe to Forever Strong Insider: https://bit.ly/4u5VSRe
Get Aldrich Chan’s books here:
https://www.drchancnc.com/books
📱Connect with Aldrich Chan, Psy.D
Website: https://www.drchancnc.com/
YouTube: www.youtube.com/@draldrichan
Instagram: https://www.instagram.com/draldrichan
Facebook: https://www.facebook.com/draldrichan
LinkedIn: https://www.linkedin.com/in/draldrichan/
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📺Watch the “Dr. Gabrielle Lyon Show” every Tuesday at 9AM EST:
YouTube: https://bit.ly/4boCFC3
Spotify: https://bit.ly/4cWTbLG
📱Connect with Dr. Gabrielle Lyon:
Instagram: https://bit.ly/4uk9adc
TikTok: https://bit.ly/3OFK3kJ
X.com: https://bit.ly/4l3YlaX
Facebook: https://bit.ly/3MBrJso
LinkedIn: https://bit.ly/3N1nrdL
Website: https://bit.ly/3NdV2kT
Books: https://bit.ly/4r6ugZK
Newsletter: https://bit.ly/402QCAj
⏰Timestamps:
00:00 - Introduction: what a neuropsychologist measures
03:25 - Mild cognitive impairment and proactive interference
04:52 - The SAD theory: separation, alienation, discord
06:30 - The default mode network and 46.9% mind wandering
08:56 - Reframing ADHD as an evolutionary advantage
18:21 - Evolutionary mismatch and hunter-gatherer comparisons
21:03 - Neuroplasticity, epigenetics, and the 24-hour timeline
24:29 - Mind-body dualism and the gut-brain connection
31:31 - What fatherhood does to the brain and testosterone
36:47 - Choice overload and the four-bit working memory limit
39:54 - Temporal discounting and building immediate feedback
43:23 - Vital signals and how to identify a core value
49:49 - Intuition, somatic markers, and the vmPFC
55:00 - The 20-watt brain versus a 10-gigawatt supercomputer
01:02:58 - Only 35% of the brain is built at birth
01:06:13 - Creativity, nothingness, and the fear of uncertainty
01:16:31 - Process, flow states, and the jazz pianist studies
01:22:53 - Mirror neurons, group selection, and the rat experiments
01:34:20 - Eustress and the line between moderate and major stress
01:44:39 - Alloparenting and what the Hadza numbers show
‼️Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
This episode includes paid sponsorships.
You might think bone density is something you build slowly over a lifetime, but nearly all of your peak bone mass is set before age 18, in a four-year window most parents never see coming. In this solo episode I break down what happens to a child's skeleton during that window, what GLP-1 medications do inside a body that's still growing, and the protocol I'd want every parent to follow. Muscle and bone are not what a body has they're what a body was built to become.
In this solo episode, Dr. Gabrielle Lyon breaks down the science of bone health in children, adolescent GLP-1 use, and muscle building in kids:
Why the four years around age 12 in girls and 14 in boys account for close to 40% of the total bone mineral a person will carry for lifeWhy a hip fracture in a healthy 29-year-old is almost always a story about a childhood building phase that never happened, often tied to a history of restriction like anorexiaWhat semaglutide and other GLP-1 medications do inside a still growing skeleton, and why no long term bone density data exists for adolescents on these drugsWhy a JAMA Network Open trial found the group combining liraglutide with resistance training lost the most weight with bone mineral density statistically unchanged, while the drug alone caused bone lossThe complete protocol for parents: track strength and function over the scale, muscle strengthening and bone loading exercise three days a week each, protein at breakfast, and a screen time floor instead of a ceilingMuscle and bone are not what a body has; they are what a body was built to become, and childhood is the only window that bone accrual and muscle development happen. Understanding pediatric bone health, sarcopenia in children, and the real research on GLP-1s and adolescents is the difference between guessing with your child's skeleton and protecting it on purpose.
Study and References:
Sarcopenic Obesity in Children - https://pubmed.ncbi.nlm.nih.gov/41995008/Sedentary Behaviors in Today's Youth (AHA) - https://www.ahajournals.org/doi/10.1161/CIR.0000000000000591Semaglutide and Body Composition (STEP 1) - https://pmc.ncbi.nlm.nih.gov/articles/PMC8089287/Peak Bone Mass Position Statement (NOF) - https://pubmed.ncbi.nlm.nih.gov/26856587/Bone Health After Exercise vs GLP-1 Treatment - https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2820308Resistance Training in Kids: An Umbrella Review - https://pubmed.ncbi.nlm.nih.gov/32757164/Thank you to our sponsors:
Timeline - up to 20% off when you subscribe and save at https://bit.ly/4x18cm5BodyHealth - Use the code LYON20 to get 20% off your first order https://bit.ly/4wZgg6NBranch Basics - Get 15% off the Premium Starter Kit at https://bit.ly/4i6iOfK with the code DRLYON.Explore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters
00:00 - Introduction
00:44 - The 29-Year-Old Who Fractured Her Hip
01:20 - Muscle and Bone Are Childhood Assets
03:01 - The Question I Keep Getting From Patients
03:39 - The 30-Year Lifting Debate Is Over
04:23 - Sarcopenic Obesity: More Muscle, Less Strength
07:01 - What a Mouse Model Reveals About Muscle Potential
08:24 - Screens: What the Data Shows
10:00 - Food, Sleep, and the Screen-Weight Loop
12:38 - GLP-1s in Teens: The STEP TEENS Trial
13:52 - The Muscle Framing Mistake Everyone Makes
16:49 - The Four-Year Window Bone Gets Built
18:02 - The Trial That Proves Exercise Protects Bone
20:29 - Prescribing Into an Unstudied Window
20:46 - Why Lifting Doesn't Stunt Growth
21:49 - Kids Get Stronger Without Building Muscle
22:29 - The Protocol: What to Do Starting Today
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
You have probably been told that testosterone is a male hormone. Women produce more of it than estrogen, and for many of us it is the first hormone to go, sometimes reading zero five years before menopause while periods are still regular. Dr. Susan Hardwick-Smith and I get into what that costs you in muscle and bone, why there are thirty-one approved testosterone products for men and none for women, and what the number on your own lab report is measuring.
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Create Her: Aging into the Healthiest Version of Yourself by Susan Hardwick-Smith MD https://www.amazon.com/Create-Her-Healthiest-Version-Yourself/dp/1637636644/ref=sr_1_3?s=books&sr=1-3
Dr. Gabrielle Lyon with Amy Pearlman Podcast
Connect with Dr. Susan Hardwick-Smith
Website: drsusan.com
YouTube: https://www.youtube.com/@drsusan
Instagram: https://www.instagram.com/drsusanofficial
TikTok: https://www.tiktok.com/@drsusanofficial
Facebook: https://www.facebook.com/drsusanofficial/
LinkedIn: https://www.linkedin.com/in/drsusanhardwicksmith/
Thank you to our sponsors:
Timeline - up to 20% off when you subscribe and save at https://bit.ly/4x18cm5BodyHealth - Use the code LYON20 to get 20% off your first order https://bit.ly/4wZgg6NBranch Basics - Get 15% off the Premium Starter Kit at https://bit.ly/4i6iOfK with the code DRLYON.Explore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonTimestamps:
00:00 - Introduction: testosterone in women
03:00 - Eighteen years in OB-GYN and the practice she left
04:57 - Thirty years in medicine, zero training on testosterone
06:40 - 31 FDA-approved products for men, zero for women
07:35 - Why women produce more testosterone than estrogen
09:20 - What the ovaries stop making at menopause
10:18 - Testosterone reading zero five years early
11:41 - Low testosterone symptoms in women
13:22 - Intrinsa, the 2004 patch the FDA turned down
19:04 - Off-label prescribing and what FDA approval means
21:35 - Cognition, breast cancer, muscle and bone
25:33 - Osteoarthritis and the anti-inflammatory theory
26:31 - Dosing fears: hair loss, acne, voice changes
28:16 - Why gels are dosed ten times higher
32:14 - The 2019 international consensus
34:00 - Dividing a 50 mg tube by ten
38:18 - The Baylor study: pellet versus gel at six weeks
40:13 - Safety data from fifty years of transgender care
45:03 - Eight years of high dosing and what it cost
46:16 - Lab reference ranges versus optimal ranges
48:28 - ELISA versus LC-MS, and what the study found
51:07 - Why free testosterone is calculated, not measured
57:58 - Tachyphylaxis and chasing the number
1:01:39 - Pellets, BioTE and where the reputation came from
1:06:33 - Delivery methods, cypionate and enanthate
1:11:47 - Whether anything raises testosterone naturally
1:13:03 - DHEA at 100 mg and what it moved
1:17:07 - Drugs that lower testosterone in women
1:20:55 - Closing thoughts on dosing and access
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
You probably ate something today with high protein printed across the front of it, and there is a good chance it did almost nothing for your skeletal muscle. There is no meaningful enforcement standard for what the front of a package is allowed to promise, and the research points to a per meal threshold most of these products do not come close to touching. Here is the number, the five myths that have to come off the table first, and how to read any label in about five seconds.
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Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyon X (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters
00:00 - Introduction: what a high protein label promises
01:03 - Protein-ification and the labeling gap
04:10 - Myth 1: protein and kidney function
06:01 - Myth 2: the 0.8 gram RDA
07:04 - Nitrogen balance and the 2026 guideline change
07:45 - Where the clinical target lands above the RDA
08:43 - Myth 3: acid ash and bone density
11:01 - Myth 4: leucine and the per meal threshold
12:12 - Four product categories in your pantry
14:44 - The 25 to 30 gram complete protein rule
15:08 - Myth 5: daily total versus per meal distribution
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
A Navy captain with 24 years of service went to medical for exhaustion, weight gain, and low mood, and was told to see a therapist and eat less. When he asked for a testosterone test his physician asked whether he had erectile dysfunction, and refused to order it when he said no. His level came back at 160; the cutoff we use in this country is 300. I've treated this population for 15 years, and roughly 27% of operators test below that number. Tim Parlatore is the attorney who wrote the Pentagon memo that now puts testosterone on the annual physical, and we get into what it says and why most men never have this hormone checked again after they leave pediatrics.
Studies & References
Cardiovascular Safety of Testosterone-Replacement Therapy - https://pubmed.ncbi.nlm.nih.gov/37326322/You Can Conquer Trauma and PTSD with Chris Frueh, PhD - https://www.youtube.com/watch?v=0olunOZM2lcSupport Kaczkowski Family's GoFundMe campaign
https://impact.navysealfoundation.org/campaign/827807/donate?utm_source=ig&utm_medium=social&utm_content=link_in_bioWant ad-free episodes? Subscribe to Forever Strong Insider: https://bit.ly/4u5VSRe
📱Connect with Tim Parlatore:
Website: https://parlatorelawgroup.com/
YouTube: https://www.youtube.com/channel/UCSSQE0_WrlegQk09nFi4QZw
Instagram: https://www.instagram.com/tparlatore/
Facebook: https://www.facebook.com/tparlatore
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LinkedIn: https://www.linkedin.com/in/timothy-parlatore/
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⏰Timestamps:
00:00 - Intro of show
02:32 - Why military service lowers testosterone
04:15 - Treated like an anabolic steroid
06:52 - Screening first, not bodybuilding
08:07 - 27% of operators test low
09:34 - The three groups of users
10:52 - The BUD/S student who died
13:00 - A captain's testosterone was 160
15:39 - Denied the test, then the wait
18:58 - Why men skip baseline testing
19:46 - Beyond operators: the wider force
21:56 - The three effects on the force
26:37 - The best biomarker for men
27:40 - Why they wanted a study first
29:04 - Health, media, and politics
37:44 - Testing and treating women
44:57 - Voluntary treatment and options
48:20 - The friend Tim lost
51:00 - Selling the science to the Pentagon
53:00 - Building a research dataset
1:05:29 - Naval Academy to defending Gotti
1:11:54 - Trial as psychological warfare
1:21:03 - The fitness turnaround
1:26:02 - The email spying scandal
1:31:06 - "I am the storm"
1:35:32 - Prosecutorial misconduct
1:41:11 - Secondary trauma and the human cost
‼️Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
This episode includes paid sponsorships.
You might think creatine is a bodybuilder's steroid you have to cycle, load, and fear for your kidneys, but it's a compound your own body already makes from three amino acids, with one of the deepest safety records in all of nutrition science. The problem isn't the creatine; it's the noise around it.
In this solo episode, Dr. Gabrielle Lyon discusses:
Why the bump creatine causes in your creatinine lab value is a metabolic artifact, not a sign of kidney damage in healthy peopleWhere the hair-loss fear came from. A single unreplicated study in one rugby player showing a 56% DHT rise, and why no research has ever directly linked creatine to hair lossHow men and women respond differently (roughly 1.5 kg of lean mass in men vs. about a third of a kilogram in women), and why women still gain real strength, grip, cognition, and recoveryWhy you can't realistically eat your way to 5 grams a day: it would take 2.5 to 3 pounds of cooked meat and fish daily, so a single scoop closes the gapThe protocol: 3–5 grams of plain monohydrate every day, no loading phase, no cycling, timing barely mattersMuscle is your organ of longevity, the tissue that clears most of the glucose in your bloodstream and defends your metabolism as you age. Creatine won't build it for you, but it raises the ceiling on the work you can do, so the training that protects that muscle pays off more. Understanding what's real and what's fearmongering is the difference between avoiding a proven tool and using it well.
Studies & References
PubMed study: https://pubmed.ncbi.nlm.nih.gov/1327657/Sports Nutrition Society: https://www.sportsnutritionsociety.org/Thank you to our sponsors:
Egg life - CTA - Find egglife wraps chillin’ in the fridge at Aldi, Whole Foods, Kroger, Target, Walmart & more - Visit https://bit.ly/3UghRHV to find a retailer near youBodyHealth - Use the code LYON20 to get 20% off your first order https://bit.ly/4gP6VtpOneSkin - Get 15% off at https://bit.ly/4xpFWuE with code DRLYONDavid Bars - Subscribe and save 10% on every order’ at https://bit.ly/4zAflMBExplore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters
00:00 - Introduction
02:47 - What Creatine Is and Isn't
03:24 - The Phosphocreatine Energy System
04:22 - Lean Mass: Water and Training Capacity
05:08 - Men vs Women Respond Differently
06:29 - Vegans, Older Adults, and Sarcopenia
07:11 - Creatine and the Brain
08:53 - The Real Safety Profile
09:31 - The Kidney and Creatinine Myth
09:57 - The 56% DHT Hair Loss Claim
10:37 - Contraindications and Screening
12:19 - Why You Can't Eat Enough Creatine
14:26 - Muscle-Centric Medicine
16:44 - How to Dose It Correctly
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Most of what we call "aging" may not be about time at all. It may be a nervous system stuck in stress, quietly draining your sleep, your recovery, and your long-term health.
In this episode, Dr. Gabrielle Lyon sits down with Dr. Kristen Holmes to discuss:
Why the hallmarks of aging- inflammation, mitochondrial dysfunction, cellular decline may be symptoms of a dysregulated autonomic nervous system, and how much of your HRV (47–65%) is genetic versus trainableHow your sleep is decided during the day, not at night, and why perceiving your day as "threatening" keeps your HRV suppressed and robs you of deep, restorative sleepThe circadian "amplitude" formula for bright days and dark nights that predicts everything from menopause symptom severity to longevity, plus the ~90 minutes of natural light almost no one getsWhy late-night eating rivals alcohol for damaging your resting physiology, and how a simple 12-hour eating window gets you most of the way thereWhy the fittest people sleep less, and how all-day movement and "exercise snacks" beat a single gym blockWhen you understand that your nervous system sits underneath your sleep, energy, and pace of aging, you stop chasing fragmented fixes and start pulling the few daily levers light, movement, meal timing, consistency that move the needle.
Studies & References
Stress and Heart Rate Variability: A Meta-Analysis and Review of the Literature — https://pmc.ncbi.nlm.nih.gov/articles/PMC5900369/How to Improve Your Circadian Rhythm with Satchin Panda PhD: https://youtu.be/gM_b4t0ARG8?si=QKfpYEAh1O5lyMw8Want ad-free episodes? Subscribe to Forever Strong Insider: https://bit.ly/4u5VSRe
Listen to “The Line” on all your favorite platforms!
YouTube: https://www.youtube.com/@TheLine-Podcast
Apple Podcasts: https://podcasts.apple.com/us/podcast/the-line-with-dr-kristen-holmes/id1846864184
Spotify: https://open.spotify.com/show/3zc3BCKHlFAlffRnd6kZXy
Get Dr. Kristen Holmes’s book, “Aligned” here: https://sites.prh.com/dr-kristen-holmes
📱Connect with Dr. Kristen Holmes:
Website: https://drkristenholmes.com/#top
YouTube: https://www.youtube.com/@TheLine-Podcast
Instagram: https://www.instagram.com/drkristenholmes/
LinkedIn: https://www.linkedin.com/in/kristen-holmes/
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📺Watch the “Dr. Gabrielle Lyon Show” every Tuesday at 9AM EST:
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⏰Timestamps:
00:00 - Intro of show
02:44 - Two types of people
03:01 - Aging as nervous system dysregulation
04:49 - The stellate ganglion block and trauma
07:34 - How much of HRV is genetic
11:13 - Emotions of trust versus fear
16:57 - Threat versus challenge appraisal
19:20 - Why modern life breaks your biology
23:24 - Structuring travel around sleep
26:16 - Circadian amplitude and contrast
28:00 - Amplitude and menopause symptoms
30:17 - What heart rate variability means
32:34 - Biggest levers for perimenopause
37:04 - Light dose and exercise snacks
40:18 - Why fit people sleep less
44:34 - Cycle syncing and training
51:56 - Meal timing and late-night eating
55:55 - Sleep-wake consistency and aging
59:43 - Exercise timing and pregnancy
01:04:54 - Why behavior precedes thought
‼️Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
This episode includes paid sponsorships.
Blowing four times the legal limit on a breathalyzer usually means one thing, but in 2015, a judge dismissed a DWI because the driver's own gut was fermenting alcohol from an ordinary carb-heavy dinner. It's called auto-brewery syndrome, and the fuel it runs on is the same load your muscle is supposed to be clearing from your blood.
In this solo episode, Dr. Gabrielle Lyon discusses:
How gut yeast overgrowth turns everyday carbs like pasta, bread, and rice into ethanol that registers as real intoxication, brain fog, dizziness, and allThe specific risk factors that open the door: dysbiosis, SIFO, repeated antibiotic use, and poorly controlled diabetes or fatty liverThe three-part protocol to correct it, reduce the yeast burden, remove the carbohydrate fuel, and rebuild the microbiome, plus the carbohydrate challenge test, most doctors never runWhy skeletal muscle is your body's primary site for clearing blood sugar, and how an under-muscled body drifts into the same insulin-resistant, dysbiotic state that lets fermentation take holdWhether or not you'll ever face this rare diagnosis, you'll walk away understanding that gut health and muscle health share one supply chain and that defending your muscle is how you starve the problem at its root.
Study & References:
Woman beats DWI — her body brews alcohol (CBS News, 2015): https://www.cbsnews.com/news/woman-beats-dwi-with-rare-defense-her-body-brews-alcohol/
Cordell & McCarthy (2013), Int. J. Clin. Med. — foundational U.S. case study: https://doi.org/10.4236/ijcm.2013.47054
Malik, Wickremesinghe & Saverimuttu (2019), BMJ Open Gastroenterology: https://doi.org/10.1136/bmjgast-2019-000325
Painter, Cordell & Sticco — Auto-Brewery Syndrome, StatPearls (NIH): https://www.ncbi.nlm.nih.gov/books/NBK513346/
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Explore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters
00:00 - Introduction
01:06 - The 2015 DUI dismissed in court
01:39 - Auto brewery syndrome defined
03:10 - The 2013 brewer's yeast case
03:46 - Why the evidence is thin
04:37 - How gut yeast ferments carbs
06:45 - Five conditions that trigger it
07:21 - SIFO vs SIBO explained
08:12 - Antibiotics and metabolic disease
10:00 - The carbohydrate challenge test
11:07 - Three non-negotiable treatments
12:53 - Muscle: the metabolic sink
15:07 - The under-muscled phenotype
17:03 - Your four directives
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Most people chase happiness as a feeling and wait for certainty before making big decisions, and both instincts quietly backfire. Dr. Arthur Brooks joins Dr. Gabrielle Lyon to break down what happiness is and how to act on it.
In this episode, Dr. Gabrielle Lyon and Dr. Arthur Brooks discuss:
The three "macronutrients" of happiness - enjoyment, satisfaction, and meaning, and why pursuing pleasure alone leads to detox, not happinessA usable rule for any hard decision: aim for roughly 80% excitement, 20% fear, and near-zero "deadness" once you have about 80% situational awarenessWhy solo pleasures don't stick if you're doing it alone, you're probably doing it wrong, and how enjoyment requires people plus memoryHow GLP-1s, SSRIs, and hormonal shifts can dull motivation, reward, and desire, and why knowing this gives you power over itSimple tech protocols: phone-free first hour, meals, and last hour that protect oxytocin, meaning, and connectionUnderstand happiness as something you build rather than something you wait to feel, and you walk away with concrete tools to decide better, connect deeper, and stop mistaking achievement for love.
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Listen to “Office Hours” on all your favorite platforms!
YouTube: https://www.youtube.com/playlist?list=PLDksUNNE9g_ZC6YJ3eG9lhZrMOG6IVuGR
Apple Podcasts: https://podcasts.apple.com/no/podcast/office-hours-with-arthur-brooks/id1832119842
Spotify: https://open.spotify.com/show/3fT0FLFsPgV2mbVjuOo3JV?si=e4d69f6725194d48
Get Dr. Arthur Brooks’ books here: https://www.arthurbrooks.com/books
📱Connect with Arthur Brooks:
Website: https://www.arthurbrooks.com/
YouTube: https://www.youtube.com/@drarthurbrooks
Instagram: https://www.instagram.com/arthurcbrooks/
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LinkedIn: https://www.linkedin.com/in/arthur-c-brooks/
🙌Thank you to our sponsors:
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📺Watch the “Dr. Gabrielle Lyon Show” every Tuesday at 9AM EST:
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Newsletter: https://bit.ly/402QCAj
⏰Timestamps:
00:00 - Intro of show
02:14 - Enjoyment, satisfaction, and meaning
02:55 - Pleasure vs enjoyment
05:04 - Why strivers can't enjoy life
07:05 - The four affect profiles
13:46 - Meaning: the protein of happiness
14:26 - Satisfaction and struggle
18:10 - Suffering equals pain times resistance
23:57 - The mistakes that sabotage happiness
28:12 - How to make hard decisions
30:00 - Excitement, fear, and deadness
33:39 - GLP-1s, motivation, and desire
36:08 - SSRIs, birth control, and attraction
38:00 - The meaning crisis and screens
41:25 - Boredom and the shock experiment
43:07 - Tech-free protocols
49:50 - Transcendence and daily practice
56:35 - The striver's lament
57:44 - Why love can't be earned
1:02:42 - Falling in love, and staying in love
‼️Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
This episode includes paid sponsorships.
You might think the number dropping on the scale is the whole win, but on a GLP-1, a meaningful share of what you're losing may be muscle, not fat, and the fiber that's supposed to help can quietly make things worse.
In this solo episode, Dr. Gabrielle Lyon discusses:
Why 25–40% of the weight lost on GLP-1 medications can be lean mass, and how to protect your muscle with adequate protein (1.2–1.5 g/kg) and resistance trainingThe GLP-1 fiber paradox and why these drugs need fiber to work, but make it hard to tolerate, and why 40–70% of patients hit GI side effects like bloating and constipationWhen to fiber max vs. fiber mine, plus how to reintroduce fiber gradually so you get the gut benefits without the bloat, bezoars, or obstruction riskGet this balance right, and you keep your muscle, calm your gut, and let the medication do its job instead of ending up bloated, constipated, and quietly losing strength.
Thank you to our sponsors:
Square - Get up to $200 off Square hardware when you sign up at square.com/go/drlyonBodyHealth - Use the code LYON20 to get 20% off your first order https://bit.ly/3TJVSsv Upgrade your kitchen with Our Place today. Visit https://bit.ly/4q3ggRp and use code DRYLON for 10% off sitewide. That’s F-R-O-M-O-U-R-P-L-A-C-E DOT COM / D-R-L-Y-O-N and use code DRLYON for 10% off sitewide. With a 100-day trial, you can try it completely risk-free.Branch Basics - Get 15% off the Premium Starter Kit at https://bit.ly/4q3ZYb4 with the code DRLYON.Explore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyon X (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters
00:00 - Introduction
00:46 - The pear bezoar and bowel obstruction
02:07 - Why 95% of Americans fall short
03:32 - The GLP-1 fiber paradox
04:18 - Why GLP-1 drugs make fiber hard to eat
05:50 - How GLP-1s slow the gut
07:40 - Bezoars, psyllium, and the 87-case series
09:12 - Fiber as therapy: titrating it right
10:03 - The muscle loss problem
11:28 - Getting the fiber and GLP-1 balance right
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
You'd think fear is what stops you from doing hard things. At 25, with zero rowing experience, Taryn Smith crossed the Atlantic alone. 3,000 miles, 46 days, and I learned that the fear was never the obstacle. It was the signal she was finally in the right place.
In this episode, Dr. Gabrielle Lyon and Taryn Smith discuss:
Why fear is a "metric of success," not a stop sign, and how to train yourself to move toward discomfort instead of away from itHow food becomes visible performance fuel when you're the only engine, and how to preserve muscle on limited calories using protein and daily amino acidsThe "long-term optimist, short-term realist" mindset that carries you through a slog with no end in sightThe post-achievement crash nobody warns you about, and why the low after a big win is predictableWhether or not you'll ever touch an oar, you'll walk away with a portable mental framework for facing anything you've been avoiding, and a clearer sense of who you are when no one's watching.
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📱Connect with Taryn Smith:
Website: https://www.tarynsmithmovement.com/
Instagram: https://www.instagram.com/tarynsmithmovement/
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Branch Basics - Get 15% off the Premium Starter Kit at https://bit.ly/4q3ZYb4 with the code DRLYON.
📺Watch the “Dr. Gabrielle Lyon Show” every Tuesday at 9AM EST:
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Spotify: https://bit.ly/4cWTbLG
📱Connect with Dr. Gabrielle Lyon:
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⏰Timestamps:
00:00 - Intro of show
02:44 - From landlocked Nebraska to the ocean
03:37 - Chasing discomfort and stacking bigger adventures
05:17 - Fear as the real metric of success
08:57 - The unglamorous first steps of training
10:51 - College, family, and why criminal defense
14:06 - Trusting the instinct and the "calling"
16:00 - Impermanence, grief, and losing her grandfather
19:08 - 46 days, the weather, and the daily slog
21:05 - Training the body: ERG, lifting, injury prevention
30:11 - Solitude and the voice in your own head
31:12 - Food as fuel: eating to power the boat
36:08 - Supplements, aminos, and protecting muscle
38:37 - The storm that almost capsized the boat
43:17 - Sharks, marlin, and the real ocean dangers
46:36 - Music, dolphins, and the bird named Jo
52:11 - Long-term optimist, short-term realist
59:41 - The question no one asks her
1:00:50 - Five beautiful things: a journaling reframe
1:11:17 - The post-row crash nobody warns you about
1:19:02 - Recovery, appetite, and relearning hunger cues
1:24:02 - Training now: flexibility over rigid discipline
‼️Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
This episode includes paid sponsorships.
You've probably worried that the glyphosate on your bread is slowly harming you. The evidence points somewhere far less obvious and far more fixable.
In this solo episode, Dr. Gabrielle Lyon discusses:
Why the real concern isn't cancer risk from your toast, but glyphosate's effect on your gut, where it can act like a selective antibiotic, hitting beneficial bacteria while sparing the harmful onesWhere the residue concentrates (grains and legumes like oats up to 1100 ppb) and why meat, milk, and eggs carry negligible amounts, so your organic dollars belong on oats and bread, not chickenThe three NHANES analyses linking higher glyphosate to weaker grip strength and greater sarcopenia risk, and why protein and resistance training matter more than agonizing over parts per billionHow switching to organic staples cuts urinary glyphosate by 71% in six days, and why "detox" products aren't the answerWhy banning glyphosate isn't a clean win, the leading alternative, 2,4-D, was a component of Agent OrangeUnderstanding where glyphosate genuinely matters lets you stop worrying about the wrong foods, spend smarter at the grocery store, and protect the two things that move the needle: your gut and your muscle.
Thank you to our sponsors:
Manukora - Go to https://bit.ly/4h6XYMQ to save 31% plus $25 worth of free gifts.Timeline - up to 20% off when you subscribe and save at https://bit.ly/3S2zg64Egglife - Find egglife wraps chillin’ in the fridge at Aldi, Whole Foods, Kroger, Target, Walmart & more. Visit https://bit.ly/3U5u55R to find a retailer near youExplore More from Dr. Gabrielle Lyon
Weekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters
00:00 - Introduction: the glyphosate question
01:15 - Is my bread killing me?
03:15 - What glyphosate is and why we spray it
05:00 - Why 82% of us test positive
05:45 - Carcinogen or not: IARC vs EPA
06:45 - Hazard vs risk and the shark
08:15 - Pure glyphosate vs Roundup
09:45 - Your gut bacteria as the target
11:00 - The fecal transplant experiment
12:00 - Glyphosate and muscle loss
13:30 - Where the residue hides
15:30 - The GMO and Agent Orange problem
17:15 - The protocol: organic swaps, gut, muscle
18:24 - Key takeaways
19:10 - The answer for my patient
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Most people think low back pain means something is wrong with their back. It's usually the hips — and the fix often starts on your living room floor.
In this episode, Dr. Gabrielle Lyon sits down with Dr. Kelly Starrett and Juliet Starrett, JD to discuss:
Why 100% of the people who fly across the country to get a consult for stubborn low back pain are missing hip extension, and how to test yours with the couch stretchThe "injury vs. incident" framework that tells you when pain needs a doctor and when you can manage it yourselfHow 20–30 minutes of floor sitting each evening restores the range of motion you thought you'd lost to ageWhy mobility is the missing third leg of the longevity triangle that roughly 90% of people skipBy the end, you'll have a simple, no-equipment way to move without pain and keep the strength and mobility that let you do what you love as you age.
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⏰Timestamps:
00:00 - Intro of show
02:33 - From performance to healthy aging
05:22 - Movement as an exercise prescription
08:21 - The movements the body should do
09:21 - Why walking isn't optional
11:07 - The gym as a movement language
14:04 - Range of motion as a pain generator
17:02 - The longevity triangle
22:19 - Why athletic people all have pain
23:12 - Injury vs. incident
25:34 - Pain is a request for change
30:22 - Humanity's lost hip extension
38:02 - Floor sitting: where to start
42:54 - Soft tissue work and foam rolling
48:20 - The couch test explained
53:24 - Why pickleball injures untrained bodies
55:11 - The ten movement vital signs
59:15 - Mobility vs. flexibility
1:00:04 - Mobility and muscle mass
1:04:34 - What kids lose in first grade
1:10:58 - The walking school bus
1:13:05 - Non-negotiables: pull-ups and shape
1:22:29 - Play as your warm-up
‼️Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
This episode includes paid sponsorships.
Over 500 published papers stand behind one of the internet's most popular peptides, but fewer than 30 of the humans studied are in them. Dr. Gabrielle Lyon separates the molecule from the marketplace so you can tell real evidence from good marketing.
In this solo episode, Dr. Gabrielle Lyon discusses:
Why BPC-157's "mountain of evidence" collapses to a 99.7% animal-to-human ratio - 544 papers, but fewer than 30 humans across three uncontrolled pilot trialsHow to place any peptide on the spectrum from FDA-approved (GLP-1s like semaglutide) to investigational to compounded, and why "GLP-1s work, so peptides work" is a trapWhat the FDA quietly did in April 2026, and why removing a dozen peptides from its safety-concern list was driven by policy pressure, not new safety dataThe 4 questions to run on any peptide before you inject level of evidence, what the study measured, where it's sourced from, and whether it's banned in tested sportWhy the "boring work", resistance training, protein-anchored nutrition, and real recovery beat almost anything in a vialIf something is going into your body through a needle, the standard has to be higher than three words on a label that say "research use only." This episode gives you the framework to protect yourself before spending a dollar or taking a shot.
Thank you to our sponsors:
Head to https://bit.ly/4ftfObn and use code DRLYON for 25% off sitewide. That is K-E-T-T-L-E and Fire dot com slash DRLYON, code DRLYON for 25% off. Also available at select Sprouts, Whole Foods, and Kroger locations nationwide.BodyHealth - Use the code LYON20 to get 20% off your first order https://bit.ly/4vZs75j OneSkin - Get 15% off at https://bit.ly/44XXQYy with code DRLYONExplore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyon X (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters
00:00 - Introduction
01:30 - What a peptide is
03:40 - The first mistake: treating peptides as one category
05:50 - GLP-1s and the "peptides work" fallacy
09:30 - FDA-approved peptides: tesamorelin and s
15:40 - Repair peptides: BPC-157 and the Wolverine stack
16:30 - 544 studies, 30 humans: the evidence gap
20:00 - The strongest case for peptides
25:30 - The strongest case against peptides
29:00 - Compounded peptides and contamination risk
30:00 - What the FDA quietly did in April 2026
33:40 - The 4 questions to ask before any peptide
37:40 - The boring work that changes your life
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Everyone on a GLP-1 is watching the scale; almost no one is watching their bones. Bone loss isn't an inevitable part of aging; it's a reversible signal that something deeper is going wrong, and it starts far earlier than most people are ever warned.
In this episode, Dr. Gabrielle Lyon sits down with Dr. Douglas Lucas, a former Stanford-trained orthopedic surgeon turned bone-health specialist, to discuss:
Why bone loss begins around 45 during perimenopause, not 50, and why waiting for your first DEXA scan at 65 is far too late to prevent itThe blind spots in the standard DEXA scan: a scan-to-scan margin of error near 6% and no read on bone quality, only quantityBone turnover markers (CTX and P1NP) you can test from blood to see whether you're building or breaking down bone in real timeWhy the "protein is bad for bones" and "alkalize your diet" beliefs are myths and why protein, minerals, and adequate calcium matter more than calcium aloneWhat rebuilds bone at home: resistance training, real impact like heel drops, and vertical vibration plates used ~10 minutes a dayUnderstanding your bones as a living, changeable organ system means you can catch loss early, measure it honestly, and reverse the trajectory, instead of accepting decline as your fate.
Thank you to our sponsors:
Head to https://bit.ly/4ftfObn and use code DRLYON for 25% off sitewide. That is K-E-T-T-L-E and Fire dot com slash DRLYON, code DRLYON for 25% off. Also available at select Sprouts, Whole Foods, and Kroger locations nationwide.BodyHealth - Use the code LYON20 to get 20% off your first order https://bit.ly/4vZs75jOneSkin - Get 15% off at https://bit.ly/44XXQYy with code DRLYONExplore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Find Dr. Doug Lucas at:
YouTube: https://www.youtube.com/@Dr_DougLucas Website: https://drdouglucas.com/Instagram: https://www.instagram.com/dr_douglucas/LinkedIn: https://www.linkedin.com/in/doug-lucas-b0243522/Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters
00:00 - Introduction: Why a Stanford surgeon quit
02:00 - The 3 a.m. case that changed everything
04:35 - Bone as a dynamic organ system
06:14 - When bone loss begins
08:20 - Rejecting age-related bone loss
09:27 - Why the conventional playbook fails
10:55 - The two classes of bone drugs
14:38 - Bone quantity vs. bone quality
17:23 - Best tests for bone quality
20:52 - T-score vs. Z-score explained
26:59 - Hormones directed at bone
27:08 - Bone turnover markers P1NP and CTX
34:57 - Bone loss starts at 45, not 50
39:23 - Calcium myths and what to eat
45:42 - How to destroy your bones
50:12 - Medications that weaken bone
54:46 - Why an ultra-runner still lost bone
55:53 - Heel drops and impact training
57:54 - Vibration plates and osteogenic loading
1:12:38 - Know your starting point
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
You've eaten red meat your whole life, so why does a steak dinner suddenly leave you covered in hives at 1 AM? A single Lone Star tick bite can rewire your immune system into a delayed allergy to red meat, and most people (and even their doctors) never connect the two.
In this solo episode, Dr. Gabrielle Lyon discusses:
Why alpha-gal reactions are delayed 2–6 hours after eating meat, and how that delay causes ER visits to be repeatedly misdiagnosedHow your blood type changes your risk (type A and O are higher-risk; type B appears protected) and why a mismatched transfusion has proven fatalThe simple alpha-gal IgE blood test to ask for, and what the numbers meanThe hidden sources beyond food: gelatin, vaccines, heparin, thyroid meds, and even heart valvesThe tiered treatment approach that resolves symptoms in about 80% of patients on meat-avoidance aloneLearn to recognize a condition that's increasingly common yet widely missed, so if it's happening to you, you'll know exactly what to test for and how to get your life back. It's not all in your head.
Thank you to our sponsors:
Cozy Earth - Go to https://bit.ly/3RLZNEv for up to 20% off!Timeline - Get 20% off your Mitopure order at https://bit.ly/4ptIchfSquare - Get up to $200 off Square hardware when you sign up at https://bit.ly/4gOCfZP #squarepodExplore More from Dr. Gabrielle Lyon
Weekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters
00:00 - Introduction
00:38 - How to spot the Lone Star tick
02:15 - Why this tick hunts you
03:40 - Where the tick is spreading now
05:10 - Diseases the Lone Star tick carries
06:30 - What alpha-gal syndrome is
08:45 - Why the reaction is delayed 2 to 6 hours
10:20 - Cofactors that make reactions worse
12:05 - Blood type and your risk level
14:30 - The transfusion danger nobody screens for
16:15 - The blood test and what the numbers mean
19:40 - Foods and hidden sources to avoid
23:10 - The three-tier treatment approach
27:00 - Hidden alpha-gal in meds, vaccines, and implants
31:20 - Preventing tick bites and getting tested
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Everyone celebrates the weight GLP-1s take off, almost no one warns you about the volume they quietly pull out of your face and the loose skin you can't train away. The fix depends entirely on the diagnosis, and knowing which category your concern falls into is what saves you time, money, and regret.
In this episode, Dr. Gabrielle Lyon sits down with Dr. Kristy Hamilton, a board-certified plastic surgeon, to discuss:
Why rapid GLP-1 weight loss deflates facial volume and creates loose skin and why the leaner and more muscular you get, the more visible that laxity becomesThe muscle-sparing breast augmentation (Preserve) that gets active women back to full training in about a week, and why placing an implant in front of the muscle protects your strengthWhich skin-tightening treatments reset structure (like internal radiofrequency) versus the surface treatments and "expensive coat rack" machines that won't touch real laxityThe real NIH data on breast implant illness and why you don't need a $30,000 detox or to have healthy tissue cut out to get reliefBy the end, you'll know what rapid weight loss really does to your skin, which procedures match which problem, and how to avoid wasting money on fixes that were never going to work for your specific situation.
Thank you to our sponsors:
Cozy Earth - Go to https://bit.ly/3RLZNEv for up to 20% off!Timeline - Get 20% off your Mitopure order at https://bit.ly/4ptIchfSquare - Get up to $200 off Square hardware when you sign up at https://bit.ly/4gOCfZP #squarepodExplore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Find Dr. Kristy Hamilton at:
Website: https://www.drkristyhamilton.com/Instagram: https://www.instagram.com/drkristyhamilton/Facebook: https://www.facebook.com/drkristyhamilton/Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters
00:00 - Introduction: GLP-1s and the plastic surgery boom
01:53 - The dark side: losing facial volume
02:40 - Fat transfers and donor-fat products
03:10 - Alloclae and the "zombie" fat
06:04 - The Miami Thong Lift explained
11:15 - Thong lift vs. BBL recovery
13:05 - Pec muscle-sparing breast augmentation
15:30 - Behind vs. in front of the muscle
20:43 - Silicone vs. saline implants
21:39 - Breast implant illness and the NIH data
24:16 - Predatory explants and the $30K program
31:33 - Implant size and the ballerina breast
37:00 - Non-surgical tightening with Quantum RF
41:00 - Are you a candidate? The pinch test
46:43 - Why surface treatments miss the structure
1:00:12 - Collagen banking for aging skin
1:03:01 - A new non-opioid pain drug
1:15:24 - Why fit women still fight loose skin
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
The longevity world has convinced a generation of women that protein is shortening their lives. The science says they've got it backwards and the people hurt most are the ones who need protein most.
In this episode, Dr. Gabrielle Lyon breaks down the protein-and-longevity fear, steelmans the strongest case against protein, then walks through what the evidence shows:
The RDA (0.8 g/kg) is a deficiency floor, not a target, the intake one camp calls "dangerously high" is what federal guidelines and expert groups now recommend (1.2–1.6 g/kg)The IGF-1–cancer link is tiny (a 3–11% risk bump vs. smoking's 1,000–2,000%), and the IGF-1–mortality curve is U-shaped: the lowest levels carry ~40% higher death riskSarcopenia roughly doubles death risk (3.5× with frailty) and perimenopause stacks anabolic resistance on top, exactly when women are told to fear the foods that defend themBy the end, you'll understand the mTOR and IGF-1 science well enough that nobody online can scare you off your own dinner, plus a simple Monday-morning plan: adequate protein, front-loaded, built on minimally processed foods, with heavy lifting to match.
Thank you to our sponsors:
BodyHealth - Use the code LYON20 to get 20% off your first order https://bit.ly/4f7ZqM5 Our Place - Upgrade your kitchen with Our Place today. Visit https://bit.ly/4vT4cEr and use code DRYLON for 10% off sitewide. That’s F-R-O-M-O-U-R-P-L-A-C-E DOT COM / D-R-L-Y-O-N and use code DRLYON for 10% off sitewide. With a 100-day trial, you can try it completely risk-free.Lucy Get 20% off your next order with code DRLYON at https://lucy.co/, or find yours in store at https://bit.ly/4ybQCxHExplore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyon X (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters
00:00 - Introduction: Is Protein Really Shortening Your Life?
02:30 - Who the Protein Fear Hurts Most
03:29 - What mTOR Is (Two Complexes)
07:29 - The RDA Deception: High vs Low Protein
12:00 - The Falcone Reanalysis of Levine 2014
16:00 - The Strongest Case Against Protein
21:00 - Why Rodent Data Isn't Human Data
26:08 - The IGF-1 Cancer Story, Link by Link
29:00 - The U-Shaped Mortality Curve
32:00 - Insulin, Carbs, and Active IGF-1
34:30 - Sarcopenia, Frailty, and Death Risk
35:55 - Perimenopause and Anabolic Resistance
38:00 - Red Meat, TMAO, and Plant Protein Myths
39:51 - The Honest Verdict: Processed Meat
44:00 - How Much Protein and Your Monday Plan
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
The parasites most Americans think of as a tropical problem are already here; showing up as fatigue, asthma, and gut issues that standard tests keep calling "normal." An estimated 1 in 20 people may carry one and never know it.
In this episode, Dr. Gabrielle Lyon sits down with Dr. Peter Hotez, a tropical-medicine physician and vaccine scientist, to discuss:
Why toxocariasis, a worm shed by household dogs and cats, may affect 5–6% of the U.S. population, with larvae migrating through the lungs and brainWhy standard PCR panels come back negative and which specific tests (antibody, fecal, eosinophil count) to ask forHow to lower your risk at home, from deworming pets on a vet schedule to knowing which symptoms warrant a targeted testWhy the popular "worm therapy for autoimmune disease" idea has the relationship backwards, worms are a leading driver of IBD and asthma, not a cureWhether you've been told your labs are fine but still feel off, this conversation gives you a clear, evidence-based framework for what to test for and how to protect your family from infections hiding in plain sight.
Thank you to our sponsors:
BodyHealth - Use the code LYON20 to get 20% off your first order https://bit.ly/4f7ZqM5Our Place - Upgrade your kitchen with Our Place today. Visit https://bit.ly/4vT4cEr and use code DRYLON for 10% off sitewide. That’s F-R-O-M-O-U-R-P-L-A-C-E DOT COM / D-R-L-Y-O-N and use code DRLYON for 10% off sitewide. With a 100-day trial, you can try it completely risk-free.Branch Basics - Get 15% off the Premium Starter Kit at https://bit.ly/4yNdfJ7 with the code DRLYON.Explore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Find Dr. Peter Hotez at:
Website: https://peterhotez.org/Instagram: https://www.instagram.com/peterhotez/Book - “Science Under Siege: How to Fight the Five Most Powerful Forces that Threaten Our World” - https://a.co/d/07P0iANSConnect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters
00:00 - Introduction: trust in science and nutrition
04:11 - Anti-parasitic drugs sold as snake oil
06:43 - How misinformation gets weaponized
18:23 - The turbo cancer claim debunked
24:41 - Finding experts you can trust
30:52 - Hepatitis B vaccine and how babies get infected
31:56 - The 75 vaccine myth: eight diseases to seventeen
35:42 - Why the COVID vaccine wasn't rushed
40:18 - Toxocariasis: the worm in stray dogs and cats
43:50 - Why parasite tests come back negative
45:57 - Hookworm in rural Alabama
48:05 - Eosinophils and how to test
50:21 - Worm therapy for autoimmune is backwards
54:19 - Deworming pets and family transmission
57:19 - Liver fluke and bile duct cancer
1:01:11 - Climate change and parasites in the US
1:03:16 - Lyme, ticks, and genomic surveillance
1:08:00 - Flu and COVID as cardiovascular threats
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
You might think microplastics are just an environmental nuisance that passes through your body, but the latest tissue studies tell a very different story. As a physician, Dr. Gabrielle Lyon breaks down where the science lands, past both the fear-mongering and the dismissiveness.
In this solo episode, Dr. Gabrielle Lyon discusses:
Why over 58% of patients in a landmark NEJM study had plastic embedded in their arterial plaque and the 4.5x higher risk of heart attack, stroke, and death that came with itHow microplastics act as a "Trojan horse," carrying endocrine-disrupting chemicals into your blood, testes, brain, and reproductive tissueWhy perimenopause and menopause are an especially vulnerable window for plastic-driven hormone disruptionThe five low-cost "Lyon Protocol" rules to cut your exposure, starting with never microwaving plastic and letting food cool before you store itThis matters because you don't need to overhaul your life or wait twenty years for perfect data to protect your cellular health; you just need the handful of small, automated decisions that move the needle on your metabolic and hormonal baseline.
Thank you to our sponsors:
Our Place - Upgrade your kitchen with Our Place today. Visit https://bit.ly/3RnCYH0 and use code DRYLON for 10% off sitewide. That’s F-R-O-M-O-U-R-P-L-A-C-E DOT COM / D-R-L-Y-O-N and use code DRLYON for 10% off sitewide. With a 100-day trial, you can try it completely risk-free.Timeline - Get 20% off your Mitopure order at https://bit.ly/4wJpFzZ Bon Charge - Save 15% at https://bit.ly/44bIoYx with code DRLYONExplore More from Dr. Gabrielle Lyon
Weekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyon X (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters
00:00 - Introduction
01:30 - What microplastics and nanoplastics are
03:00 - Where plastics show up inside us
04:30 - The UCSF systematic review
06:10 - Inflammation, cytokines, and thyroid
07:40 - Plastic in arterial plaque and the 4.5x risk
10:10 - The strongest skeptic arguments
13:00 - Lead, asbestos, and trans fats
14:40 - The Trojan horse for hormone disruptors
16:10 - Reproductive aging and menopause
17:50 - Where Dr. Lyon lands
19:40 - The Lyon protocol: five rules
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
You've been told that 10,000 steps a day is enough to keep you healthy but when it comes to your bones and your muscles, walking falls short, and the science explains exactly why. The real drivers of strength, bone density, and lasting health are load, intensity, and resistance, not just movement.
In this episode, Dr. Gabrielle Lyon sits down with Dr. Alyssa Olenick, a PhD in exercise metabolism and ultramarathoner who blends endurance and strength training, to discuss:
Why the "interference effect," the fear that cardio cancels your strength gains, is overblown for almost everyone, and what causes the carryover fatigueHow most women train too lightly, believing they're at a 9 out of 10 when they're closer to a 5, and never trigger real muscle adaptationWhy estrogen is not the primary driver of muscle, resistance training is, and what that means through the menopause transitionThe early warning signs of low energy availability, including cycle changes that show up long before a missed period, and the rapid bone loss that followsHow to structure strength, power, and cardio together, and fuel it properly without sabotaging recoveryYou'll walk away knowing how to train for strength, power, and bone density that lasts and why being undertrained, not fragile, is the real problem for most women.
The July Forever Strong Foundations Challenge begins July 6, 2026. This 4-week challenge is designed to help you build a stronger, more energized you through sustainable nutrition, training, and lifestyle habits. Register here: https://bit.ly/4p3DW7U
Thank you to our sponsors:
Our Place - Upgrade your kitchen with Our Place today. Visit https://bit.ly/3RnCYH0 and use code DRYLON for 10% off sitewide. That’s F-R-O-M-O-U-R-P-L-A-C-E DOT COM / D-R-L-Y-O-N and use code DRLYON for 10% off sitewide. With a 100-day trial, you can try it completely risk-free.Timeline - Get 20% off your Mitopure order at https://bit.ly/4wJpFzZBon Charge - Save 15% at https://bit.ly/44bIoYx with code DRLYONExplore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Find Alyssa Olenick at:
Website: https://doclyssfitness.com/Instagram: https://www.instagram.com/doclyssfitness/The Running Ebook: https://doclyssfitness.com/running/Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters
00:00 - Introduction
02:09 - Hybrid vs. concurrent training defined
05:03 - Where beginners should start
10:12 - Movement vs. exercise vs. training
11:30 - The interference effect: the boogeyman
16:55 - Nervous system fatigue and bar speed
20:07 - Why running fatigues you more than cycling
26:04 - Fuel use, fat oxidation, and the crossover
34:39 - Mitochondria and metabolic flexibility
39:13 - What we don't know about women's physiology
44:18 - Type one vs. type two muscle fibers
46:00 - Testosterone, training age, and muscle gain
48:02 - What we confidently know about women and muscle
49:43 - Estrogen is not the muscle driver
53:14 - Menstrual cycle, performance, and perception
58:03 - Training the mind, not just the body
1:02:18 - The aerobic guidelines and doing more
1:06:26 - The 2026 resistance training guidelines
1:16:49 - Squat, hinge, push, pull explained
1:22:04 - Why walking isn't enough for bone
1:26:14 - Power, plyometrics, and power-penia
1:35:33 - Programming cardio without killing gains
1:41:03 - Low energy availability and warning signs
1:47:38 - Protein and carbs for the hybrid athlete
1:53:52 - The seasons approach: spend a year lifting
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
You were told your testosterone is "normal" so why do you still feel exhausted, weak, and off? The number on your lab report was never built for you, and your own genetics may be the reason it doesn't match how you feel.
In this solo episode, Dr. Gabrielle Lyon discusses:
Why the standard 300–1000 ng/dL range ignores your age, comorbidities, and genetics, and why two men with identical labs can feel completely differentHow CAG repeats determine whether your body "catches" the testosterone you produce, meaning you might need 400 to feel great while someone else needs 800Why the 80-year-old fear that testosterone fuels prostate cancer is built on a single flawed 1941 study, and what the androgen saturation model proves insteadHow everyday endocrine disruptors BPA in receipts, phthalates in personal care, atrazine in tap water quietly lower your testosterone even when you eat clean and train hardThe correct AUA testing protocol your doctor may be skipping: two early-morning, fasted measurements plus actual symptoms, not one afternoon blood drawUnderstanding how your own body uses testosterone lets you walk into your doctor's office armed with facts instead of frustration and stop being told you're "fine" when you don't feel it.
Thank you to our sponsors:
OneSkin - Get 15% off at https://bit.ly/4ekX9gt with code DRLYONExplore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyon X (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters
00:00 - Introduction
00:55 - Why one reference range fails everyone
01:45 - Men with normal labs who feel terrible
02:40 - Dismantling the prostate cancer myth ahead
03:40 - Testosterone decline by age data
04:30 - It's comorbidities and environment, not just age
05:10 - Endocrine disruptors and how they work
06:30 - How EDCs lower testosterone
08:00 - Common offenders and where they hide
09:00 - Receipts, atrazine, and performance apparel
10:30 - Reducing your chemical exposure
11:45 - The prostate cancer paradigm shift
12:20 - The flawed 1941 study
13:00 - The androgen saturation model
14:00 - Testosterone therapy with prostate cancer data
15:00 - What happens when you block androgens
15:45 - Androgens and brain protection
16:45 - CAG repeats and genetic variability
18:30 - The rain and buckets analogy
19:30 - AUA testing and diagnosis protocol
21:00 - Symptoms, targets, and safe monitoring
22:15 - Muscle-centric application and recap
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
The July Forever Strong Foundations Challenge begins July 6, 2026. This 4-week challenge is designed to help you build a stronger, more energized you through sustainable nutrition, training, and lifestyle habits. Register here: https://bit.ly/4gCmoNR
For 40 years you've been told 0.8 grams of protein per kilogram is "enough" but the scientists who contributed the reports behind the new 2025–2030 Dietary Guidelines say not a single study has ever shown that number beats eating more.
In this episode, Dr. Gabrielle Lyon sits down with Dr. Don Layman and Dr. Heather Leidy, the protein researchers who developed the scientific reports informing the new U.S. Dietary Guidelines, to discuss:
Why the guidelines reprioritized protein to a healthy range of 1.2–1.6 g/kg and why that still isn't technically "high protein"
Why you don't really have a protein requirement, but an essential amino acid requirement and what that means for your brain, mood, and antioxidant production
Who's quietly falling short: roughly 20% of women over 60 sit below the RDA, and adolescent girls are among the most consistently deficient
How to spot real protein on a label (Layman's 10-gram threshold) and why most "+protein" snacks are just fairy dust
What a higher-protein breakfast does to afternoon cravings, backed by fMRI brain-reward data
Walk away knowing how much protein you actually need, why "enough to avoid deficiency" and "enough to thrive" are two different numbers, and how to build every meal around protein first so you're covered on the nutrients that matter most.
Thank you to our sponsors:
OneSkin - Get 15% off at https://bit.ly/4ekX9gt with code DRLYON
Explore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.com
Weekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/
Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/
Find Dr. Donald K. Layman at:
Website: https://www.metabolictransformation.com/
Instagram: https://www.instagram.com/layman.don
Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/
TikTok: @drgabriellelyon
X (Twitter): https://x.com/drgabriellelyon
Facebook: https://www.facebook.com/doctorgabriellelyon
Chapters
00:00 - Introduction
02:00 - The biggest change in 45 years
03:36 - Why the guidelines are so controversial
06:09 - Process complaints vs. the science
08:25 - Protein was always there, just hidden
10:26 - Is 1.6g really high protein?
13:00 - Half of people are below average
13:45 - The randomized trials that say no benefit
16:57 - Why cherry-picked studies mislead
18:42 - Amino acids are essential, fiber isn't
21:17 - Does protein only matter with lifting?
33:33 - Nitrogen balance and its blind spot
40:02 - The carbohydrate RDA everyone ignores
47:37 - The nine essential amino acids
49:49 - Why aging makes deficiency worse
53:36 - Going below 50% animal protein
58:25 - Protein quality and carbohydrate dilution
1:04:34 - Hitting protein when you're small
1:08:53 - High-protein breakfast and the teen brain
1:10:19 - fMRI: blunted food cravings
1:18:40 - The saturated fat sticking point
1:26:30 - The 10% number from thin air
1:40:17 - Is protein in everything fairy dust?
1:46:42 - Smart high-protein snacks
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
The receptor that switches off your appetite on a GLP-1 drug is the same one wired into your reward circuitry, your hormones, and your blood vessels, which means when you turn down hunger, something else may be getting turned down too, and for most people taking these drugs, nobody ever checked.
In this solo episode, Dr. Gabrielle Lyon discusses:
Why the same drug class can improve sexual function in men with obesity while potentially dampening it in lean or postmenopausal women — and why the deciding factor isn't the drug, it's the bodyHow rapid weight loss raises SHBG, the protein that soaks up free testosterone, so a "normal" total testosterone result can hide a real deficit your bloodwork won't flagWhy women make up 60–70% of GLP-1 prescriptions yet the entire evidence base for female sexual function is two case reports, with zero validated questionnaires in any pivotal trialThe three-tier action plan for anyone on or about to start a GLP-1 — baseline your sexual function first, get free testosterone tested, and protect muscle with protein and resistance trainingWhether you're on a GLP-1 drug or considering one, you'll walk away knowing exactly what to measure before you start and what to watch for after — so a change in your sexual health gets caught as the vital sign it is, instead of being quietly dismissed.
Thank you to our sponsors:
Cozy Earth - Go to https://bit.ly/44qcXtu for up to 20% off! Lucy - Get 20% off your next order with code DRLYON at https://bit.ly/3QEpYMX or find yours in store at https://bit.ly/3SGAEv3 .Kettle & Fire - Head to https://bit.ly/4oJokGu and use code DRLYON for 25% off sitewide. That is K-E-T-T-L-E and Fire dot com slash DRLYON, code DRLYON for 25% off. Also available at select Sprouts, Whole Foods, and Kroger locations nationwide.Explore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyon X (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters
00:00 - Introduction
01:30 - The 35-year-old patient case
04:00 - The question: harm or help?
05:00 - The case against: the 4.5x ED study
06:30 - FAERS database and 182 reports
08:00 - Reward circuits, blood flow, and SHBG
11:00 - Women are 70%, the data is two case reports
12:30 - The case for: detection bias explained
15:00 - Validated studies show testosterone rising
17:00 - GLP-1 vs testosterone therapy and fertility
19:00 - Same receptor, different body
22:00 - Cross-examination: holes in both sides
26:00 - Why the drugs may not all be the same
30:00 - Confidence levels: what Lyon actually believes
33:00 - Tier 1: baseline, hormones, protein, training
35:00 - Tier 2 and 3: dose, molecule switch, adjuncts
36:30 - Your sexuality is a vital sign
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
You might think more cardio is the key to aging well but Lisa Smith-Batchen, who has run 135 miles through Death Valley ten times, says it's strength that actually carries you through the decades.
In this episode, Dr. Gabrielle Lyon sits down with Lisa Smith-Batchen, one of the most decorated ultra-endurance athletes in American history and a 10-time Badwater 135 finisher, to discuss:
Why being strong matters more than being fast and why "it's not the running that helps me run, it's being strong"The first movement everyone should train at any age: sit to stand, followed by squats, wall sits, lunges, and pushupsWhy cutting protein after 60 backfires, and why Lisa fuels on roughly 80% protein calories during racesHow to start lifting late, her 85-year-old client went from 5-pound weights to 230-pound farmer carriesThe fall that ended her father's life, and why "pick your feet up" became her mission for aging athletesYou'll walk away with a clear, muscle-first blueprint for staying strong, mobile, and independent for life — and the motivation to start today instead of waiting for another Monday.
Thank you to our sponsors:
Cozy Earth - Go to https://bit.ly/44qcXtu for up to 20% off!Lucy - Get 20% off your next order with code DRLYON at https://bit.ly/3QEpYMX or find yours in store at https://bit.ly/3SGAEv3 .Kettle & Fire - Head to https://bit.ly/4oJokGu and use code DRLYON for 25% off sitewide. That is K-E-T-T-L-E and Fire dot com slash DRLYON, code DRLYON for 25% off. Also available at select Sprouts, Whole Foods, and Kroger locations nationwide.Explore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Find Lisa Smith-Batchen at:
Website: https://dreamchaserevents.com/Instagram: https://www.instagram.com/coachlisasmithbatchenFacebook: https://www.facebook.com/lisa.smithbatchenConnect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters
00:00 - Introduction
02:10 - From marathon to the Badwater 135
05:31 - The first race and learning the hard way
06:41 - Inside the pain cave
13:46 - Why she went back ten times
16:51 - Bonking, hydration, and what changed
21:12 - Finding your why
28:04 - Running for something greater
33:25 - Strong over fast: the real secret
35:59 - The lifting myths men and women believe
44:13 - Where a beginner should start
47:02 - Sit to stand: the non-negotiable move
48:56 - The habit that killed her father
51:11 - Why falls are so devastating
54:14 - The danger of low-protein advice for older adults
59:00 - Stop waiting for Monday
01:01:37 - Fueling: protein, sodium, and calories per hour
01:13:01 - Why a DNF isn't failure
01:18:13 - Unfinished business and the right choice
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
What does it actually mean to win at the highest level? In this powerful compilation, I’m with 2024 CrossFit Games champion James Sprague, 2023 CrossFit Games champion Laura Horvath, and legendary endurance coach Chris Hinshaw to unpack the mental game behind elite performance, the vulnerability that follows victory, and why champions are often more fragile in the moments just after they win. What does winning mean to you right now?
Connect with James Sprague
Website: https://games.crossfit.com/athlete/900251
YouTube: https://youtube.com/@spraguerrrr?si=zTrH9d5valcjlq-t
Instagram: https://www.instagram.com/spraguerrrr/
Facebook: https://www.facebook.com/spraguerrrr/
Connect with Laura Horvath
Website: https://games.crossfit.com/athlete/591912
YouTube: https://youtube.com/@kaduzs23?si=3j8mXAnf38H7uGvi
Instagram: https://www.instagram.com/laurahorvaht/?hl=en
Facebook: https://www.facebook.com/laurhorvath/
TikTok: https://www.tiktok.com/@laurahorvaht
X: https://x.com/laurahorvaht
Connect with Chris Hinshaw
Website: https://www.aerobiccapacity.com/
Instagram: https://www.instagram.com/hinshaw363/
Facebook: https://www.facebook.com/hinshaw363/
Thank you to our sponsors:
Bodyhealth - Use the code “LYON20” to get 20% off your first order! https://bit.ly/4r2ImeF
Our Place - Use code “DRLYON” for 10% of sitewide. https://bit.ly/4r77SiU
Manukora - save 31% plus $25 worth of free gifts. https://bit.ly/4sglER1
Watch the “Dr. Gabrielle Lyon Show” every Tuesday at 9AM EST:
YouTube: https://bit.ly/4boCFC3
Spotify: https://bit.ly/4cWTbLG
Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/
TikTok: https://www.tiktok.com/@drgabriellelyon
X (Twitter): https://x.com/drgabriellelyon
Facebook: https://www.facebook.com/doctorgabriellelyon
Timestamps:
00:00 - Intro of Show
00:52 - The Rogue Invitational and qualifying
01:41 - Applying friction in elite training
02:27 - Why winners are vulnerable
02:47 - CrossFit and HYROX recovery demands
03:23 - Active versus passive rest
04:14 - Why records keep breaking
05:18 - Training by feel without wearables
06:16 - Mastering movement before intensity
07:21 - Reframing pain as growth
08:25 - How CrossFit events are structured
09:47 - Building structural integrity
10:38 - The three bases of the sport
11:34 - Getting comfortable being uncomfortable
‼️Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
This episode includes paid sponsorships.
Most men think erectile dysfunction is a bedroom problem and low testosterone is just a fact of getting older. This roundtable makes the case that both are early warning lights for your heart, your metabolism, and your long-term health and that ignoring them can cost you a decade.
In this episode, Dr. Gabrielle Lyon sits down with urologists and men's health specialists Dr. Mohit Khera, Dr. Larry Lipshultz, and Dr. Tobias Köhler to discuss:
Why a 35-year-old with ED carries a ~15% risk of heart attack or stroke within 7 years, ~3.5x the risk of depression, and ~30% odds of diabetes or prediabetes and why a prescription alone misses all of itWhy "age-related" testosterone decline is largely a misnomer: a healthy man shouldn't drop significantly with age, so falling T usually signals something reversible underneathHow testosterone became the single best blood marker of a man's overall health, and the case for annual screening that almost no man getsWhat the TRAVERSE trial changed when the FDA removed testosterone's cardiovascular warning in 2025, debunking the prostate-cancer and heart-attack fearsThe 2-minute monthly self-exam every man should do to catch testicular cancer early, when it's ~99% curableIf you've been told your symptoms are "just aging" or you love a man who refuses to see a doctor. This conversation shows you how to read the signals your body gives long before a crisis hits.
Thank you to our sponsors:
Body Health - Use the code LYON20 to get 20% off your first order https://bit.ly/4efgBuMTimeline - Get 20% off your Mitopure order at https://bit.ly/49LSbYzBranch Basics - Save 15% at https://bit.ly/4uuw4x3 with code DRLYONExplore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Find Dr. Larry Lipshultz at:
Instagram: https://www.instagram.com/lipshultzmd?igsh=NTc4MTIwNjQ2YQ==Website: https://www.larrylipshultz.com/YouTube: https://www.youtube.com/@DrsAmyandLarryFind Dr. Tobias Kohler
Instagram: https://www.instagram.com/tobiaskohlermd?igsh=NTc4MTIwNjQ2YQ==X: https://x.com/sexhealthmd?s=11Find Dr. Mohit Khera
Instagram: https://www.instagram.com/drmohitkhera?igsh=NTc4MTIwNjQ2YQ%3D%3DX: https://x.com/DrMohitKheraWebsite: https://drmohitkhera.com/Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: @drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters
00:00 - Introduction
01:30 - What doctors got wrong about testosterone
05:05 - The prostate cancer myth, debunked
07:12 - The best marker of a man's health
11:51 - Is age-related decline actually real?
14:15 - How obesity crushes testosterone
18:11 - Testosterone and reversing diabetes
20:06 - GLP-1 versus testosterone
25:20 - What "low testosterone" really means
29:05 - Dosing, CAG repeats, and microdosing
42:34 - The TRAVERSE trial and FDA reversal
47:10 - The prostate saturation point
56:49 - Peptides, explained
01:03:00 - Why ED is a check engine light
01:08:26 - The desert of men's health care
01:11:06 - The case for annual screening
01:16:45 - Varicoceles and male fertility
01:20:03 - How to check for testicular cancer
01:26:44 - Final advice for men
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Your ego isn’t the enemy, but if you’re not actively controlling it, it is running your team, your home, and your most important relationships. Jamie Cochran, COO of Echelon Front, has spent 13 years helping leaders fix the root cause most of them never look for.
The Women’s Leadership Assembly live event runs January 5–7, 2027 in Palm Springs. A free monthly webinar series runs year-round. More details here: https://events.echelonfront.com/product/assembly-004/?utm_source=google&utm_medium=cpc&utm_campaign=22652941380&utm_content=&utm_term=&utm_source=google&utm_medium=paid&utm_campaign=22652941380&utm_content=&utm_term=&gadid=&gad_source=1&gad_campaignid=22662710098&gclid=CjwKCAjwxITRBhBYEiwA6mZm7VZs1jY-jUq1ugoigo8XEDkYsRsSEpOs2eblax5TQOW-9LT_K-hVhBoC1RkQAvD_BwE
Thank you to our sponsors:
Timeline - Get 20% off your Mitopure order at https://bit.ly/4dW6BGNBodyHealth - Use the code LYON20 to get 20% off your first order https://bit.ly/4uR4NWBUpgrade your kitchen with Our Place today. Visit https://bit.ly/4dSD4Pz and use code DRLYON for 10% off sitewide.Explore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Find Jamie Cochran at:
Website: https://echelonfront.com/
YouTube: https://youtube.com/@echelonfront?si=2x5aCudkXTvicfJO
Instagram: https://www.instagram.com/jamielynncochran/
Facebook: https://www.facebook.com/jamie.cochran.7/
LinkedIn: https://www.linkedin.com/in/jamie-lynn-cochran-5ab79013
Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters
00:00 Intro of Show
01:33 The Spartan Warrior Selection
02:25 Why Female Leadership Is Misunderstood
06:35 Are Leadership Tools Evolving or Constant?
07:12 What Is Extreme Ownership?
11:44 Owning It All vs. Doing It All
12:34 Female Leadership: Strength vs. Confidence vs. Aggression
17:57 Imposter Syndrome: Healthy or Dangerous?
23:37 Leadership Skills: Natural or Trainable?
31:00 Detachment from Emotion: On Making Better Decisions
32:32 Healthy Competition Against Women
36:20 Jamie’s Thyroid Cancer Diagnosis and Practicing Detachment
48:12 Avoidant Leaders and Default Aggressive Bias for Action
51:96 Top 3 Mistakes Leaders Make
52:43 The Leadership Capital Framework
57:54 The PIOS Framework: Problem, Impact, Ownership, Solution
1:00:10 When to End a Professional Relationship
1:04:29 The Women’s Leadership Assembly: Origin Story
1:07:05 Impact of Social Media on the Confidence of Young Girls
1:13:35 Compounding Habits that Improve Leadership over Time
1:14:55 Discipline as a Parenting Tool
1:22:07 Recognising when your Leadership Capacity is Failing
1:24:51 Women’s Assembly in January 2027: Palm Springs
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Most men think erectile dysfunction is a bedroom problem. It's actually one of the earliest warning signs of cardiovascular disease, capable of showing up three to five years before a heart attack.
In this episode, Dr. Gabrielle Lyon sits down with Dr. Amy Pearlman, a urologist trained in men's sexual health, to discuss:
Why ED is a symptom of vascular health, not a standalone disease and how the artery feeding the heart is roughly double the size of the one feeding the penis, so problems show up "down there" firstWhy "normal" testosterone can be meaningless, and the questions to ask before accepting a lab result that didn't flagHow daily erections preserve penile tissue the way water keeps a sponge supple and why disuse can cost noticeable size over just a few monthsThat cardiovascular exercise can rival ED medication for improving erectile function, making your heart health the real fixHow to track erectile fitness before there's a problem, instead of waiting until something breaksBy the end, you'll understand the single signal your body uses to flag heart and metabolic risk early and the simple, mostly drug-free steps that protect both your cardiovascular health and your sexual function for life.
Thank you to our sponsors:
Manukora - Go to https://bit.ly/3RCMrKx to save 31% plus $25 worth of free gifts.Timeline - Get 20% off your Mitopure order at https://bit.ly/4dW6BGNBon Charge - Save 15% at https://bit.ly/433Xi2B with code DRLYONExplore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Listen to "Pearls of Wisdom" on all your favorite platforms!
Spotify: https://open.spotify.com/show/4uOhWn5DeVXO7D2ppa0RoV
Apple Podcasts: https://podcasts.apple.com/us/podcast/pearls-of-wisdom/id1617916659
Find Dr. Amy Pearlman at:
Website: https://www.primeinstitute.us/
YouTube: https://youtube.com/@docamyurology?si=oJ2LZ_sxMPYTaK41
Instagram: https://www.instagram.com/amypearlmanmd/
LinkedIn: https://www.linkedin.com/in/amy-pearlman-54a2b0208
Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: @drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonTimestamps
00:00 - Introduction
01:25 - Erections predict cardiac events
01:41 - The pen and artery analogy
03:40 - No health milestones for men
07:52 - Normal structure and function
11:45 - The five S's of men's health
21:24 - Why "normal" testosterone misleads
25:00 - Testosterone and fertility risk
31:05 - Steroids versus FDA-approved agents
41:13 - The untreated 25-year-old
43:56 - Sperm health and home testing
52:02 - Peyronie's disease and injury
1:01:34 - Protein, nutrition, supplements
1:05:09 - Daily Cialis as a pre-workout
1:13:32 - The sponge analogy
1:15:31 - Erectile fitness tracking
1:23:05 - The penis pump, used right
1:27:24 - Restoring lost size
1:35:00 - Traction and girth enhancement
1:46:00 - Women's anatomy and pleasure
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Most people think the cholesterol number on their lab report tells them whether their heart is at risk. But former National Lipid Association President Dr. Kevin Maki explains that LDL is just one piece of a much bigger picture and focusing on it alone can mean missing the markers that matter most.
In this episode, Dr. Gabrielle Lyon sits down with Dr. Kevin Maki, former President of the National Lipid Association and co-editor-in-chief of the Journal of Clinical Lipidology, to discuss:
Why ApoB and Lp(a) are better predictors of heart risk than LDL and why only about 2% of people ever get Lp(a) testedWhat a beef-vs-chicken feeding study revealed about red meat and cholesterol (the LDL results came back identical at 112 mg/dL)The evidence behind the seed oil debate, including why higher linoleic acid levels tracked with lower inflammation markers across a 2,000-person datasetWhy the balance of cholesterol-raising and cholesterol-lowering foods matters more than saturated fat aloneThe simple "ABCs" framework: A1c, blood pressure, cholesterol - for actually lowering long-term cardiovascular riskBy the end, you'll know which numbers actually predict heart risk, which tests to ask your doctor for, and how to cut through the conflicting noise around fat so you can make evidence-based decisions for the long haul.
Thank you to our sponsors:
OneSkin - Get 15% off at https://bit.ly/4tZnOpk with code DRLYONBodyHealth - Use the code LYON20 to get 20% off your first order https://bit.ly/48SJ7AC Amp - Visit https://bit.ly/3RcmqBz to get your AI-powered at-home gym for smarter, personalized training.Explore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Find Dr. Kevin Maki at:
Midwest Biomedical Research: https://www.mbclinicalresearch.com/ LinkedIn: / kevin-c-maki-phd-497ba34Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: @drgabriellelyon X (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters
00:00 - Introduction
00:31 - Dr. Kevin Maki and the National Lipid Association
01:04 - New dietary guidelines and the LDL confusion
02:04 - What raises and lowers LDL cholesterol
03:51 - Cholesterol levels from birth through puberty
05:11 - The lipid panel kids should get before age 11
06:42 - Lp(a): the test only 2% of people get
08:18 - ApoB and the three risky particle types
11:35 - Do we have evidence for "lower is better"?
14:09 - The FLASH-GLICK risk factor framework
17:10 - The 10% saturated fat guideline explained
19:36 - Many dietary patterns can be healthy
24:50 - Beef vs. chicken: identical LDL results
27:10 - The balance of fatty acids that matters
29:24 - Olive oil vs. corn oil feeding study
31:00 - Lower for longer: 40-year risk reduction
34:15 - Genetic cholesterol disorders and risk
40:33 - The omega-3 index and why it matters
49:10 - Are seed oils really driving inflammation?
53:11 - How seed oils are processed and refined
1:07:48 - Inherited beliefs and outdated nutrition science
1:08:54 - Butter vs. cheese and high-fat dairy surprises
1:14:48 - Exercise effects on HDL and triglycerides
1:21:20 - The ABCs of reducing cardiovascular risk
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Colorectal cancer is now the leading cancer killer in adults under 50, and patients in their 20s are presenting with metastatic disease that has nothing to do with family history. Most physicians are still telling young patients with rectal bleeding that it's probably just hemorrhoids and that's costing lives.
In this episode, Dr. Gabrielle Lyon sits down with Dr. Michelle Pearlman, a board-certified gastroenterologist and founder of a Miami-based gastro-metabolic clinic, to discuss:
The specific warning signs every adult under 50 should never ignore, regardless of age including rectal bleeding, unintentional weight loss, and persistent abdominal painWhy GLP-1 medications like Ozempic and Zepbound are being miscategorized as weight loss drugs when they're actually metabolic reprogrammers with applications in fatty liver, sleep apnea, and inflammationThe protein, fiber, and resistance training protocol Dr. Pearlman uses to protect muscle mass in patients on GLP-1 therapyHow hormone replacement therapy combined with GLP-1s is changing body composition outcomes for perimenopausal women and why current guidelines are still 20 years behind the dataDr. Pearlman's personal osteoporosis diagnosis at 39, despite being a lifelong bodybuilder, and what it revealed about the diagnostic gaps in standard medicineThis conversation gives you the framework to recognize the warning signs most physicians are still missing, and the foundational habits; nutrition, resistance training, and hormone optimization that protect your gut, bones, and muscle through midlife and beyond.
Thank you to our sponsors:Cozy Earth - Go to https://bit.ly/4teXQhz for up to 20% off!
Timeline - Get 20% off your Mitopure order at https://bit.ly/4eLBWhB
Lucy - Get 20% off your next order with code DRLYON at https://bit.ly/42HiUlc, or find yours in store at https://bit.ly/3RfGnYa
Amp - Visit https://bit.ly/3RcmqBz to get your AI-powered at-home gym for smarter, personalized training.
Explore More from Dr. Gabrielle LyonPremium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.com
Weekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/
Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/
Find Dr. Michelle Pearlman at:Instagram: https://www.instagram.com/michellepearlmanmd/Website: https://www.primeinstitute.us/Connect with Dr. Gabrielle LyonInstagram: https://www.instagram.com/drgabriellelyon/
TikTok: https://www.tiktok.com/@drgabriellelyon
X (Twitter): https://x.com/drgabriellelyon
Facebook: https://www.facebook.com/doctorgabriellelyon
Chapters00:00 - Introduction: Colorectal cancer under 50
01:15 - The gastro-metabolic approach explained
03:30 - Why nutrition isn't taught in GI fellowship
05:45 - When the colonoscopy is normal but patients suffer
07:00 - Weight, reflux, and visceral fat
09:15 - PPIs, bone density, and long-term risk
11:30 - Three things to never do for gut health
14:00 - Ultra-processed food and early-onset cancer
16:45 - Rectal bleeding, warning signs, and age
19:00 - Screening guidelines and the obesity gap
22:30 - GLP-1 medications: history and mechanism
27:15 - Hunger, cravings, and food noise
30:00 - The stigma around metabolic medications
33:45 - Side effects: nausea, reflux, constipation
38:30 - Compounded formulations and pharmacy safety
42:00 - Hair loss, protein, and supplementation
45:15 - Pill versus injection delivery systems
49:30 - Fiber, the microbiome, and short-chain fatty acids
54:00 - GLP-1s plus hormone replacement therapy
58:45 - Testosterone, Kyzatrex, and women's bone health
1:03:00 - Pearlman's osteoporosis diagnosis at 39
1:09:30 - The diagnostic gap in standard medicine
1:14:00 - Building Bite MD and the future of nutrition tech
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Most parents are quietly paving the road their kids were supposed to learn to walk on by themselves and Jocko Willink has spent 20 years watching what happens when that road is too smooth.
In this episode, Dr. Gabrielle Lyon sits down with Jocko Willink, retired Navy SEAL commander, founder of Echelon Front, and bestselling author of Extreme Ownership and Discipline Equals Freedom, to discuss:
Why the "apex parent / apex kid" mindset is a quiet trap, and what to do instead of paving the roadHow nature vs nurture actually plays out and what you can and cannot shape in your childThe one trait Jocko wants his kids to inherit (and why every virtue becomes a vice when pushed to the extreme)The lie that successful, high-functioning people tell themselves about wanting moreThe single most important trait of a great leader and the one habit Jocko says will make every other part of your life better starting tomorrowYou'll walk away with a clearer operating system for the kind of parent, leader, and person you actually want to be and the one habit Jocko swears is the highest-ROI move any human can make.
Thank you to our sponsors:
BodyHealth - Use the code LYON20 to get 20% off your first order https://bit.ly/48SJ7ACOur Place - Visit https://bit.ly/4c8OrAB and use code DRLYON for 10% off sitewide.Branch Basics - Get 15% off the Premium Starter Kit at https://bit.ly/4eu4Mm8 with the code DRLYON.Amp - Visit https://bit.ly/41BvjXj to get your AI-powered at-home gym for smarter, personalized training.Watch on Spotify. If you’re subscribed to Spotify Premium, you don’t get any Spotify ads on my video.
Explore More from Dr. Gabrielle LyonPremium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Instagram: https://www.instagram.com/drgabriellelyon/
TikTok: @drgabriellelyon
X (Twitter): https://x.com/drgabriellelyon
Facebook: https://www.facebook.com/doctorgabriellelyon
Chapters00:00 - Introduction: Leadership and parenting are the same skill
03:24 - Nature vs nurture and the kids who won't compete
06:56 - The guardrails of failure
07:48 - Dharma and the path kids are meant to walk
09:17 - The one trait Jocko wants his kids to inherit
11:33 - What daughters should learn about men from their fathers
13:32 - How men and women experience fear differently
14:24 - Rebuilding trust after good people do bad things
18:34 - Letting your daughter do cheerleading
21:22 - Hiring people by putting them in the real environment
24:22 - The lie successful people tell themselves
29:16 - Strategic thinking vs the donut decision
35:18 - What failure teaches that success cannot
38:25 - Why Jocko stopped being about himself
44:09 - Aging, losing movements, and rage against the dying of the light
46:49 - Why a leader has to be in physical shape
50:41 - The single most important trait of a leader
54:09 - The one habit that changes everything
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Most men don't know they have a pelvic floor, and most doctors aren't trained to look for dysfunction in it. The result: testicles are being surgically removed for pain that's actually neuropathic, at double the rate of a far more effective nerve-sparing procedure.
In this episode, Dr. Gabrielle Lyon sits down with Dr. Susan Macdonald, a board-certified urologist, surgical program director at Penn State, and one of only ~30 U.S. specialists treating chronic pelvic pain in men, to discuss:
Why "prostatitis" is often the wrong diagnosis, and how rounds of antibiotics mask the real problemThe male pelvic floor anatomy almost no medical school teaches, and how to recognize dysfunction in yourself or a patientOff-label medications (Cymbalta, gabapentin, amitriptyline) that are quietly transforming chronic pelvic pain treatmentWhy erectile dysfunction is rising sharply in teenagers, and the role pornography plays in rewiring young brainsWho actually qualifies for a penile implant, and what the surgery really involvesIf you've been told your pain is "all in your head," or you're a clinician seeing patients fall through the cracks, this conversation gives you the framework, the language, and the next steps to find real answers.
Thank you to our sponsors:
Manukora - Go to https://www.MANUKORA.com/DRLYON to save 31% plus $25 worth of free gifts.Timeline - Get 20% off your Mitopure order at https://www.timeline.com/lyonBONCHARGE - Save 15% at https://boncharge.com/ with code DRLYONExplore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Find Dr. Susan Macdonald at:
Instagram: https://www.instagram.com/drsusanmacdonald/
X (Twitter): https://x.com/smacdonald_md
LinkedIn: https://www.linkedin.com/in/susan-macdonald-506324191/
Connect with Dr. Gabrielle Lyon
Instagram: https://www.instagram.com/drgabriellelyon/
TikTok: @drgabriellelyon
X (Twitter): https://x.com/drgabriellelyon
Facebook: https://www.facebook.com/doctorgabriellelyon
Chapters
00:00 - Introduction
01:42 - Meet Dr. Susan Macdonald
03:00 - The high-powered lawyer nobody could help
05:01 - Why testicle pain is 5% of urology visits
07:49 - Men have a pelvic floor (and what it does)
12:46 - How a man knows he has pelvic floor dysfunction
21:30 - Why these muscles are "too tight" in men
26:33 - Chronic pain rewires the brain
29:21 - Stress, trauma, and the mind-body connection
33:29 - Stretching, breathing, and self-treatment at home
36:21 - The medications that actually work (Cymbalta, gabapentin)
44:34 - Muscle relaxers, acupuncture, and the guidelines panel
55:09 - Sexual trauma and chronic pelvic pain
01:00:08 - The "pain plus" diagnostic framework
01:05:23 - The micro-surgical denervation surgery
01:08:36 - Erectile dysfunction in 17-year-olds
01:11:00 - How porn rewires young men's brains
01:18:27 - 40% of men by 40, 50% by 50
01:23:39 - Penile implants: who qualifies, how they work
01:28:10 - Stage 4 cancer at 42 and the pivot to teaching
01:34:17 - Living big with finite time
01:39:00 - Closing message to chronic pain patients
If you found this episode valuable, share it with someone who would benefit from it.
This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Most people are chasing the wrong version of strength and paying for it with pain, poor movement, and a body that breaks down faster than it should. In this episode, Dr. Gabrielle Lyon sits down with Mark Bell, elite powerlifter, entrepreneur, and founder of Slingshot, to discuss:
Why strength training is essential at every age but most people are defining "strength" too narrowlyHow modern life has created an "exercise deficiency," and why artificial exercise is the only fixThe truth about fat, protein, and the biggest nutrition mistakes holding people back from lasting weight lossThe emerging peptide and drug landscape, and what it means for the future of health optimizationWhy forcing your kids to move isn't cruelty, it's one of the most protective things you can do as a parentWhether you're 25 or 75, this episode will challenge how you think about movement, muscle, and what it actually means to be strong physically and mentally.
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OneSkin - Get 15% off with code DRLYON — https://bit.ly/4tZnOpkAmp - Get your AI-powered at-home gym for smarter personalized training — https://bit.ly/41BvjXjBranch Basics - Get 15% off the Premium Starter Kit with the code DRLYON — https://bit.ly/4eu4Mm8BodyHealth - Get 20% off your first order with the code LYON 20 — https://bit.ly/4etWlr5Explore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content — https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights — https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon's clinical team — https://drgabriellelyon.com/new-patient-inquiry/Find Mark Bell at:
https://www.instagram.com/marksmellybell/https://www.youtube.com/@MarkBellSuperTrainingSlingshot: https://originmaine.com/Connect with Dr. Gabrielle Lyon
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: @drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters
00:00 – Introduction
02:48 – Mark Bell's Motto
07:00 – Mind-Body Strength Connection
10:45 – Wrestling > Powerlifting > Entrepreneurship Journey
17:37 – Rationale of Goals
22:04 – Effects of Consistency and Efficiency in Training
32:55 – Recommended Training and Lifestyle Modalities
37:32 – Artificial Exercise vs. Exercise Deficiency
37:47 – "Artificial Exercise" and "Exercise Deficiency"
39:36 – Impact of Physical Activity in Children
44:57 – Biggest Mistake in Weight Loss
50:46 – Overconsumption is a Problem
53:17 – Era of GLP-1, Peptides, and Steroids
1:02:28 – Training to Decrease Mortality
1:03:33 – Cancer Research Updates
1:04:36 – Collective Research on Supplementation
1:16:50 – Influencing Children to Engage in Physical Activities
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Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
We are living through one of the most significant shifts in medicine in generations, and most people don’t fully understand what it means. Dr. Christle Guevarra joins me to zoom out on the entire GLP-1 landscape; from the drug’s origins as a modest diabetes treatment in 2005 to today’s third-generation medications still moving through clinical trials, and what all of it means for the future of obesity, performance, and longevity.
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Explore More from Dr. Gabrielle Lyon:
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Connect with Dr. Christle Guevarra
YouTube: https://bit.ly/4vDMVQa
Instagram: https://bit.ly/4mxnfAc
Get Dr. Christle Guevarra’s book, “Bodybuilding Anatomy”: https://bit.ly/3ODIDYd
📺Watch the “Dr. Gabrielle Lyon Show” every Tuesday at 9AM EST:
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📱Connect with Dr. Gabrielle Lyon:
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TikTok: https://bit.ly/3OFK3kJ
X.com: https://bit.ly/4l3YlaX
Facebook: https://bit.ly/3MBrJso
⏰Timestamps:
00:00 Intro of Show
06:48 Changes in the Fat Loss Landscape
06:54 Engagement in Competitive Powerlifting
11:29 Perspectives on GLP-1 Medication
26:10 Perimenopause Journey
27:13 Topamax
28:03 Urosepsis
30:23 Weight Loss Programming
31:43 Patients' Decision to Take GLP-1
37:44 Risks and Effects on Taking GLP-1
38:10 Pancreatitis
41:40 Fen-Phen (Fenfluramine/phentermine) / Ephedra
45:59 Who Should Not Take GLP-1?
49:24 Proper Nutrition to Support Taking GLP-1
52:14 Recommendation for the New Dietary Guidelines
59:01 Residency and Sports Medicine Fellowship
1:02:38 Are Athletes Recommended to Take GLP-1?
1:08:49 Lack of Randomized, Controlled Trials for Peptides
1:10:38 Key Take-away's from Dr. Christle
1:13:24 Should Women Weigh Themselves?
1:21:02 Should Women Lift Weights?
1:21:55 What's Next for Dr. Christle?
‼️Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
This episode includes paid sponsorships.
The moment you decide to show up publicly, you open the door to opinions from people who would never say those things to your face. Dominique Sachse, journalist, author, and content creator who has lived her life on camera for over three decades, gets honest about what it costs to put yourself out there, why online cruelty is a psychology problem more than a content problem, and how “Teflon Dom” developed the thick skin to let none of it redirect her.
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Listen to "Over 50 & Flourishing" on all your favorite platforms!
YouTube: https://bit.ly/4meCeyY
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📱Connect with Dominique Sachse:
Website: https://bit.ly/41VFUfC
YouTube: https://bit.ly/41YNk1C
Instagram: https://bit.ly/3OgHXHU
Facebook: https://bit.ly/41G41iB
TikTok: https://bit.ly/4sXBbWB
LinkedIn: https://bit.ly/3PYRvIf
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❤️Amp - Visit https://bit.ly/4cwLoDJ to get your AI-powered at-home gym for smarter, personalized training
📺Watch the “Dr. Gabrielle Lyon Show” every Tuesday at 9AM EST:
YouTube: https://bit.ly/4boCFC3
Spotify: https://bit.ly/4cWTbLG
📱Connect with Dr. Gabrielle Lyon:
Instagram: https://bit.ly/4uk9adc
TikTok: https://bit.ly/3OFK3kJ
X.com: https://bit.ly/4l3YlaX
Facebook: https://bit.ly/3MBrJso
LinkedIn: https://bit.ly/3N1nrdL
Website: https://bit.ly/3NdV2kT
Books: https://bit.ly/4r6ugZK
Newsletter: https://bit.ly/402QCAj
⏰Timestamps:
00:00 Intro of Show
02:10 Dominique’s Mission
05:13 Women’s Reinvention with Aging
12:07 Handling People’s Opinions in the Media
18:03 Why Dominique Wrote “Life Makeover”
26:08 Activating One’s Faith through Life’s Challenges
29:16 Decision to Leave the News Business
34:12 Traditional Media Transitioning to Online Media
37:09 How to Curate Information
38:42 Effectively Communicating with Journalism and Research Skills
43:17 Managing Conflicts On-and-Off Air
45:28 The Aging Process
49:53 Personal Training with Body Builders
52:33 Changes in Training and Nutrition
54:49 Importance of Discipline
1:00:28 How Dominique Makes Decisions
1:04:03 Dominique’s Goal and Message
1:08:46 Midlife Wellness Protocols
1:14:29 What’s Next for Dominique?
‼️Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
This episode includes paid sponsorships.