? Good news! My original Instagram is back! Please follow my original account at https://www.instagram.com/nathalieniddam/ and also my backup account at https://www.instagram.com/longevitywithnat/. Today, I?m joined by the incredible Dr. Nora Abdul-Hussein, a physician-scientist, medical geneticist, and one of the leading voices in the field of genomic medicine. In this episode, Dr. Abdul-Hussein and I dig into a huge question?why do two people taking the exact same GLP-1 medication have such wildly different results, from weight loss to side effect profiles? She shares her unique path from internal medicine to cutting-edge population genomics, and how her work at 23andMe is beginning to answer some of medicine?s toughest puzzles. Episode Timestamps: Introduction: podcast focus on genetics, peptides, and longevity ... 00:00:00 Dr. Nora Abdul-Hussein?s background and journey in genomic medicine ... 00:07:01 Prevention and population-scale genetics ... 00:08:06 Power of genetic insights for personal lifestyle choices ... 00:14:40 Barriers to adopting genetics in clinical practice ... 00:16:41 Pharmacogenomics and the move toward personalized prescribing ... 00:17:21 Launching a large-scale study on GLP-1 genetics ... 00:19:41 Discovery: GLP-1 receptor gene variants linked to weight loss and nausea ... 00:22:40 Risk calculators and personalized expectations for GLP-1s ... 00:27:26 Broader genomics: diet, exercise, and response variability ... 00:28:24 Avoiding genetic determinism and emphasizing holistic care ... 00:29:29 Findings for tirzepatide and the GIP receptor ... 00:34:20 Population differences and ancestry?s impact on results ... 00:38:07 Is genetic information ready for prime time in GLP-1 therapy? ... 00:41:12 Clinical implications beyond ?calories in, calories out? ... 00:43:01 GLP-1s: potential for non-weight related conditions ... 00:44:48 Personalized medicine: integrating genomics with other data ... 00:51:02 Reducing shame and embracing genes as tools for prevention ... 01:00:02 Genomic information as an empowering health strategy ... 01:01:30 Study insights and validation: self-reporting and sample diversity ... 01:05:40 Protecting privacy and building trust in genomics ... 01:13:32 Final thoughts: embrace your genes and use the data for healthspan ... 01:20:10 Where to learn more and wrap-up ... 01:21:18 Our Amazing Sponsors: Mitopure Gummies by Timeline ? Supports healthier cellular energy, muscle strength, recovery, and healthy aging with clinically proven Urolithin A?without artificial sweeteners, colors, flavors, or unnecessary fillers. Head to timeline.com/NAT20 to get Mitopure starting at just $99 and save an additional 20% on your order. Manukora Honey ? A delicious real-food source of prebiotics, Manukora's high-MGO Manuka honey helps support your gut microbiome, digestion, and immune health with just one teaspoon a day. Head to MANUKORA.com/NAT to save up to 31% plus receive $25 worth of free gifts with the Starter Kit. Just Thrive 90-Day Probiotic ? A spore-based probiotic that survives stomach acid to arrive 100% alive in your gut, supporting better digestion, nutrient absorption, immunity, and less bloating. Start your first 90-day subscription today and you'll get a FREE 90-day supply of Digestive Bitters (a $90 value) to help optimize digestion and support healthy appetite regulation. Click HERE to learn more. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Original Instagram Backup Instagram Dr. Bill Lawrence Episode

? Good news! My original Instagram is back! Please follow my original account at https://www.instagram.com/nathalieniddam/ and also my backup account at https://www.instagram.com/longevitywithnat/. Today, I?m joined by Dan Pardi, a pioneering researcher who has dedicated years to understanding sleep, performance, and?the real focus of today?s conversation?the science of human energy. Dan unpacks how modern life is quietly draining our brain?s battery, and why brain energy, not just the march of time, could be the hidden driver of longevity. We dive into why short ?exercise snacks? can outperform marathon workouts for keeping your brain sharp, how chronic stress and relentless screen time undermine cognitive performance, and the surprising reasons creatine is fast becoming a game-changer for brain health, not just muscle building. Visit qualialife.com/nathalie and use code NATHALIE at checkout to save 15%. Episode Timestamps: Welcome and podcast introduction ... 00:00:00 Exercise snacks and their impact on cognitive performance ... 00:07:29 How modern stress and technology deplete brain energy ... 00:12:12 Environmental influences on sleep and energy ... 00:13:35 Redefining aging as an energy management issue ... 00:18:41 Muscle function, healthspan, and holistic longevity ... 00:21:53 Why the brain demands so much energy ... 00:25:30 Brain energy, cognitive decline, and examples like Alzheimer?s ... 00:29:07 Creatine?s history in sports and its cellular mechanism ... 00:35:38 Creatine?s cognitive benefits and how it reaches the brain ... 00:49:20 Sleep, adenosine, and energy maintenance ... 00:54:39 Creatine safety, kidney health, and gender differences ... 00:57:22 Bloating, body composition, and dosing myths ... 01:05:30 Why innovate creatine supplements and formulation upgrades ... 01:11:57 Micronization, magnesium, sodium, and absorption ... 01:13:00 Product testing and user experience ... 01:17:31 Future of brain energy science in longevity ... 01:22:45 Closing resources and medical disclaimer ... 01:28:47 Our Amazing Sponsors: Quantum Upgrade ? A 24/7 quantum energy streaming service designed to support energy, focus, sleep, recovery, and a more balanced nervous system, backed by placebo-controlled research showing measurable improvements in stress-related brain activity and heart rate variability. Try it free for 15 days with no credit card required at quantumupgrade.io/NAT and use code NAT15.  MitoQ Hormonal Metabolic Control ? A targeted formula designed to support women through the hormonal and metabolic shifts of perimenopause and menopause, featuring S-Equol for healthy estrogen signaling, B. breve to support the gut-hormone connection, and chromium to help maintain healthy blood sugar balance. Head to MitoQ.com/nat and use code NAT10 to try it for yourself. Nature's Marvels Bioregulators by Profound Health - Natural bioregulators designed to support your body's own cellular communication and healthy aging, with targeted formulas for everything from brain and immune health to sleep and vitality. Visit profound-health.com and use code NAT15 for 15% off your first order. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Original Instagram Backup Instagram Dr. Bill Lawrence Episode

? Good news! My original Instagram is back! Please follow my original account at https://www.instagram.com/nathalieniddam/ and also my backup account at https://www.instagram.com/longevitywithnat/. Today, I?m joined by Dr. Elisa Port, a trailblazing breast cancer surgeon and passionate advocate for women?s health. And the author of The Breast Advice In our conversation, Dr. Port traces her evolution from general surgery into breast surgery, sharing how the deeply collaborative decision-making with patients became her life?s calling. She gives an inside look at the optimism she found in this field?where advances in treatment have dramatically improved survival, offering hope and empowerment to countless women. Episode Timestamps: Welcome and show introduction ... 00:00:00 Path to breast surgery and collaborative care ... 00:05:45 Breast cancer, survival rates, and longevity factors ... 00:08:57 Impact of weight and lifestyle on recurrence risk ... 00:10:45 Dangers of information overload and misinformation ... 00:13:38 Evaluating new screening tests and lacking validation ... 00:16:17 Dense breast tissue and adjunctive screening ... 00:19:20 Galleri blood test and research gaps ... 00:22:08 Top lifestyle risk factors: weight and alcohol ... 00:23:32 Self-awareness and moderation with food and alcohol ... 00:27:45 GLP-1 medications and modern weight challenges ... 00:33:40 Compounding health issues from obesity ... 00:37:37 Long-term effects and benefits of weight loss drugs ... 00:40:09 Hormone replacement, risk, and individualized care ... 00:45:34 AI?s impact on breast imaging and detection ... 00:56:29 Physical and mental recovery after treatment ... 01:00:31 Future hopes: Cures and compliance ... 01:04:53 Summary of optimal breast health strategies ... 01:06:27 Our Amazing Sponsors: Wolverine by LVLUP Health ? A peptide-based formula designed to support recovery, tissue repair, and musculoskeletal health, helping your body bounce back from workouts and everyday wear and tear. Head to lvluphealth.com and use code NAT for 15% off your order. MitoBlue by Wizard Sciences ? A longevity-focused formula that combines pharmaceutical-grade methylene blue with NMN, PQQ, fisetin, and apigenin to support healthy mitochondria, cellular renewal, and healthy aging. Learn more at wizardsciences.com and use code NAT15 for 15% off. Vita Zero-Age Exosomes by Vitali Skincare ? a regenerative ?stacking? formula with exosomes, GHK-Cu, niacinamide, and glutathione designed to support your skin at a cellular level rather than just the surface; go to www.vitaliskincare.com/?ref=Nat20 and use code NAT20 for 20% off. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Original Instagram Backup Instagram Dr. Bill Lawrence Episode

? Good news! My original Instagram is back! Please follow my original account at https://www.instagram.com/nathalieniddam/ and also my backup account at https://www.instagram.com/longevitywithnat/. Today, I?m joined by Dr. Jill Crista, a pioneering voice in environmental medicine and a relentless detective when it comes to chronic, mysterious illness. In our conversation, Dr. Crista reveals how she uncovered the hidden world of mold and mycotoxins?not just as respiratory irritants, but as stealthy drivers of fatigue, brain fog, hormone disruption, and accelerated aging. She shares her early experiences working with ?non-responders? in Lyme disease, and how uncovering toxic mold exposures transformed her entire understanding of whole-body health. Visit https://alighthealthformulas.com/nathalieniddam and code NATHALIENIDDAM Episode Timestamps: Podcast intro and host background ... 00:00:00 Peptides, bioregulators, and expert busting myths ... 00:02:10 Foundations of hydration and health ... 00:03:55 Mold as a multi-system problem, not just respiratory ... 00:06:12 Clinical questionnaires for mold and Lyme ... 00:12:02 Why mold illness is misunderstood ... 00:13:29 Mycotoxins vs. visible mold, and detection tips ... 00:14:17 Detox reactions and mold warning signs ... 00:22:46 Remediation challenges: ?dead? mold ... 00:28:35 Different responses to mold exposure ... 00:29:43 Protective nutrition and the microbiome ... 00:31:19 Modern buildings and mold risks ... 00:33:35 Break the Mold: the 5-step approach ... 00:35:23 Pitfalls: skipping avoidance and early antifungals ... 00:35:38 Bioflavonoids and alternative binders ... 00:37:24 Aloe as a safe binder option ... 00:41:27 Mold recovery ?crashes? and toxicity ... 00:42:58 Managing exposure when you can?t remediate ... 00:45:19 Long COVID and its overlap with mold ... 00:50:43 Essential oils and neuroinflammation support ... 01:04:08 Mold, accelerated aging, and healthspan ... 01:07:03 When to suspect mold in longevity ?non-responders? ... 01:09:44 Key questions, testing, and early action steps ... 01:10:23 Hope, healing, and the importance of optimism ... 01:16:31 Our Amazing Sponsors: Bioregulators & Peptides Summit by DrTalks ? Cut through the confusion around peptides and bioregulators with free expert-led sessions covering healthy aging, metabolism, recovery, fasting, and the latest science in a practical, easy-to-understand way. Register for free today at https://drtalks.com/summits/NAT. Electrolyze by BEAM Minerals - Electrolyze is a plant-based fulvic mineral formula that delivers a full spectrum of highly bioavailable trace minerals and electrolytes to support hydration, nutrient delivery, and cellular energy. Head to beamminerals.com/NAT20, use code NAT20, and get 20% off your first order. Mitopure Gummies by Timeline ? Supports healthier cellular energy, muscle strength, recovery, and healthy aging with clinically proven Urolithin A?without artificial sweeteners, colors, flavors, or unnecessary fillers. Head to timeline.com/nat20 to get Mitopure starting at just $99 and save an additional 20% on your order. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Original Instagram Backup Instagram Dr. Bill Lawrence Episode

? Good news! My original Instagram is back! Please follow my original account at https://www.instagram.com/nathalieniddam/ and also my backup account at https://www.instagram.com/longevitywithnat/. Today, I?m joined by Dr. Bill Lawrence, a leading researcher in longevity and pioneer in clinical studies on peptide bioregulators. Over the past eight years, Dr. Lawrence has dedicated himself to asking the big questions in longevity science: Do these interventions really work, and which strategies actually move the needle when it comes to living longer, healthier lives? Where to find Bioregulators: Visit Profound Health and use code NAT15 for 15% off your first order. Previous Episodes: #394 How Bioregulator Peptides HALVE Mortality: Telomere Reversal, Organs REGENERATED & the 8-Year Experiment With Dr. Bill Lawrence #256: Dr. Bill Lawrence: Bioregulator Peptides, New Insights on Aging, DNA Repair Mechanisms & the Impact of Stress on Telomere Length Dr Bill Lawrence: Reversing Aging PART 2 Bioregulator Peptides Effect on DNA Methylation Clinical Trial Episode Timestamps: Welcome and podcast introduction ... 00:00:00 Bioregulators: sourcing and beginner guidance ... 00:03:37 Defining hope, hype, and science in longevity ... 00:09:02 Framework for evidence-based interventions ... 00:11:08 Lifespan, healthspan, and longevity distinctions ... 00:19:31 Animal studies vs. human longevity research ... 00:27:51 Recognizing hype and influencer marketing ... 00:33:33 Experimental therapies: gene editing & reprogramming ... 00:36:06 GLP-1 drugs and healthspan evidence ... 00:41:03 Proven criteria for legitimate longevity interventions ... 00:46:03 Mortality risk reduction: sleep, lifestyle, and relationships ... 00:47:47 Evidence ladder: from mice to human studies ... 00:53:13 Peptide bioregulators: research history and mechanisms ... 01:01:19 Organ regeneration and biological age reversal ... 01:21:20 Epigenetic age, pace of aging, and case studies ... 01:34:00 Our Amazing Sponsors: C.A.R.E. Mitochondrial Moisturizer Young Goose ? An upgraded cellular skincare formula featuring Methylene Blue and Liposomal Creatine to support mitochondrial function, skin barrier health, and resilient, hydrated skin. Click HERE and use code NAT10 to save on C.A.R.E. Mitochondrial Moisturizer. NEW Magnesium Breakthrough Advanced 10 by BIOptimizers ? A magnesium formula featuring 10 bioavailable forms of magnesium, plus active vitamin B6 and ionic trace minerals, designed to support sleep, recovery, stress, and metabolic health. Visit bioptimizers.com/bionat and use code BIONAT for 15% off, exclusive bonuses, and free shipping on select orders. Grass-Fed Whey by Puori - A third-party tested, grass-fed whey protein delivering 21g of protein per serving, with every batch tested for over 200 contaminants and results available via a QR code for complete transparency. Head to puori.com/NAT20 and use code NAT20 to get 32% off your first subscription order, plus a free premium shaker bottle. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Original Instagram Backup Instagram Dr. Bill Lawrence Episode

Today, I?m mixing things up with a special episode that takes you on a tour through some of the most compelling moments from the past quarter. Rather than a typical interview or solo deep dive, I?ve curated standout clips from episodes that lit a fire under important longevity conversations and resonated deeply with both me and the team. We?ll cover the markers that could signal your body?s terrain is welcoming to cancer, practical strategies for calming an agitated nervous system when mast cell issues show up (especially with age), and the truths about Lyme disease that most people?maybe even your doctor?completely miss. You?ll also hear expert advice on EMF protection that separates real solutions from the noise, and gather insights on long COVID that go way beyond the headlines and arm you with things you can actually do. Whether you?re here to pick up new tips for optimizing your health or just looking for that nudge of inspiration to dig deeper into your own wellness journey, this longevity mix has something for you. Follow my NEW Instagram @longevitywithnat and my existing Instagram @nathalieniddam (that?s back?for now). Episodes In This Recap: #436: Is Your Body?s Terrain Hospitable For Cancer? Affordable Lab Tests, Metabolic Flexibility, and Emotional Foundations With Dr. Nasha Winters #434: Are You Aging Like Someone Else? (How To Find Your PERSONAL Path to Healthspan) With Sandra Kaufmann #450: Lyme, Bartonella & Babesia EXPOSED: Hidden Vectors, Lost Lives, and the Battle for Early Detection With Nicole Bell #435: FINALLY! A Guide To What YOU Can Do About EMF Exposure To Better Protect Your Body With R Blank #447: Gut AWAKENING: The Silent Epidemic of Spike Protein, Long Covid, and Accelerated Aging | Dr. Robin Rose Episode Timestamps: Welcome and podcast introduction ... 00:00:00 Quarterly highlight episode explained ... 00:00:31 How to share feedback and engage with the show ... 00:01:04 Key episode topics previewed: cancer, mast cells, Lyme, EMFs, long COVID ... 00:01:58 Dr. Nasha Winters: cancer risks and early lab markers ... 00:02:49 Why CBC, CMP, and the ?trifecta? matter for longevity ... 00:08:56 Terrain over tumor: tracking health before imaging reveals problems ... 00:14:01 Dr. Sandy Kaufmann: mast cells in aging and solutions ... 00:14:18 How hormone changes expose mast cell vulnerability ... 00:24:01 Nicole Bell: Lyme misdiagnosis and chronic illness links ... 00:29:23 Why Lyme often goes undetected and the need for better testing ... 00:33:05 New diagnostics and empowering patient action ... 00:41:27 R. Blank: what non-native EMFs are and why they matter ... 00:44:37 EMF exposure, health risks, and practical home strategies ... 00:55:22 Dr. Robin Rose: what drives long COVID and what to do ... 00:59:10 Gut health, spike protein, and actionable recovery steps ... 01:06:19 Conclusion and safety reminder ... 01:11:55 Our Amazing Sponsors: Vita Zero-Age Exosomes by Vitali Skincare ? a regenerative ?stacking? formula with exosomes, GHK-Cu, niacinamide, and glutathione designed to support your skin at a cellular level rather than just the surface; go to www.vitaliskincare.com/?ref=Nat20 and use code NAT20 for 20% off. MitoBlue by Wizard Sciences ? A longevity-focused formula that combines pharmaceutical-grade methylene blue with NMN, PQQ, fisetin, and apigenin to support healthy mitochondria, cellular renewal, and healthy aging. Learn more at wizardsciences.com and use code NAT15 for 15% off. Wolverine by LVLUP Health ? A peptide-based formula designed to support recovery, tissue repair, and musculoskeletal health, helping your body bounce back from workouts and everyday wear and tear. Head to lvluphealth.com and use code NAT for 15% off your order. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Original Instagram Backup Instagram Dr. Bill Lawrence Episode

? Good news! My original Instagram is back! Please follow my original account at https://www.instagram.com/nathalieniddam/ and also my backup account at https://www.instagram.com/longevitywithnat/. For years, we've been told to prioritize our muscles, our hormones, and our heart health?but what about our brains? Today's conversation explores why women are at a greater risk for Dementia and Alzheimer's, why brain changes begin decades before symptoms appear, and why so many warning signs are dismissed as "just stress" or "just menopause." I'm joined by Emma Heming Willis, co-founder of Make Time Wellness and Dr. Nicole Beurkens, Make Time Wellness Scientific Advisor, for an incredibly honest discussion that blends cutting-edge neuroscience with deeply personal experience. We discuss cognitive resilience, how to care for your brain NOW, hormone health, and the simple habits that can help protect your brain for years to come. If you've ever experienced brain fog, become a caretaker for someone you love, or wondered what you can actually do to protect your cognitive health, this episode is one you won't want to miss. Visit https://maketimewellness.com/NAT and use code NAT for 20% off products.  Episode Timestamps: Women's Brain Health Is Being Overlooked ... 00:00:00 Why Women's Brain Health Has Been Ignored ... 00:09:13 Why Alzheimer's Begins Decades Before Diagnosis ... 00:16:26 Brain Fog vs. Dementia: Knowing The Difference ... 00:17:31 Hormones, Menopause & The Brain ... 00:22:08 Becoming A Caregiver Overnight ... 00:25:41 The Hidden Health Risks Of Caregiving ... 00:26:19 How To Tell Normal Brain Changes From Dementia ... 00:30:00 Why Women Need More Self-Compassion During Menopause ... 00:34:00 The Power Of Community & Social Connection ... 00:36:07 What Every Woman Should Know About Brain Health Earlier In Life ... 00:39:33 Grief, Anger & Caregiver Guilt ... 00:44:22 How Dementia Changes An Entire Family ... 00:47:25 Why Women Face A Higher Alzheimer's Risk ... 00:50:26 The Caregiver Wake-Up Call ... 00:49:00 Genetics vs. Lifestyle: Can You Lower Your Risk? ... 00:59:50 The Biggest Modifiable Dementia Risk Factors ... 00:56:16 Sleep, Blood Sugar & Brain Health ... 01:08:00 Supplements That Support Cognitive Health ... 01:10:00 Where To Learn More ... 01:24:32 Our Amazing Sponsors: Countdown Insiders ? A $21/month membership funding mitochondrial research, with exclusive education, expert conversations, member experiences, and partner perks. Longevity listeners get their first month free with code NATHALIE. Learn more at https://joincountdown.org/membership/  Blue Cannatine by Troscriptions ? Precision-formulated troches designed to support sustained focus and mental clarity, helping you stay sharp through long workdays, recording sessions, travel, and everything in between. Visit troscriptions.com/NATPODCAST or use code NATPODCAST at checkout to save 10% off your first order. LongeFera by Regenerive - A precision-formulated ashwagandha supplement that isolates four key bioactive compounds to support a healthy stress response, cognitive function, balanced inflammation, and cellular longevity?without the fillers and inconsistent extracts found in many products. Head to regenerive.co and use code NAT25 for 25% off your order. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

? Please don?t forget to follow my NEW Instagram account at https://www.instagram.com/longevitywithnat/ My guest today is James LaValle R.Ph., C.C.N. M.T. DHM, DHPh, one of the pioneers in functional and metabolic medicine, and we're unpacking the silent process he calls metaflammation?the chronic, low-grade inflammation that can quietly drive everything from fatigue and insulin resistance to hormone imbalances and accelerated aging. Episode Timestamps: Introduction & Why "Normal" Labs Can Be Misleading ... 00:00:00 Why Treating Symptoms Without Addressing the Cause Doesn't Work ... 00:10:53 The Cascade From Metabolic Dysfunction to Chronic Disease ... 00:13:38 Why Standard Blood Tests Often Miss Early Disease ... 00:17:08 Hidden Blood Markers & Pattern Recognition in Lab Work ... 00:19:39 Why We Normalize Feeling Bad ... 00:23:17 Empowering Patients Instead of Accepting "Getting Older" ... 00:25:05 Environmental Toxins, Mold, Heavy Metals & The Exposome ... 00:31:00 Detoxification: What Actually Works? ... 00:35:00 Finding a Practitioner Who Looks at the Whole Picture ... 00:36:53 GLP-1 Medications: Benefits, Risks & Common Misconceptions ... 00:44:20 Essential Amino Acids, Creatine & Preserving Lean Mass ... 00:58:24 Titrating GLP-1s vs. "Microdosing" ... 00:60:11 Wearables, Biomarkers & The Future of Health Tracking ... 01:26:52 Rapid-Fire Questions: Most Underrated Biomarker, Sleep & Recovery ... 01:27:10 Our Amazing Sponsors: MitoQ Hormonal Metabolic Control ? A targeted formula designed to support women through the hormonal and metabolic shifts of perimenopause and menopause, featuring S-Equol for healthy estrogen signaling, B. breve to support the gut-hormone connection, and chromium to help maintain healthy blood sugar balance. Head to MitoQ.com/nat and use code NAT10 to try it for yourself. Nature's Marvels Bioregulators by Profound Health - Natural bioregulators designed to support your body's own cellular communication and healthy aging, with targeted formulas for everything from brain and immune health to sleep and vitality. Visit https://profound-health.com/?Aff=Longevity15 and use code NAT15 for 15% off your first order. C.A.R.E. Mitochondrial Moisturizer by Young Goose ? An upgraded cellular skincare formula featuring Methylene Blue and Liposomal Creatine to support mitochondrial function, skin barrier health, and resilient, hydrated skin. Click HERE and use code NAT10 to save on C.A.R.E. Mitochondrial Moisturizer. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

? Please don?t forget to follow my NEW Instagram account at https://www.instagram.com/longevitywithnat/ Most people think that if they can just find the right mold test, they'll finally have their answer. But what if that's exactly what's keeping them stuck? In this episode, I'm joined once again by mold investigator and building health expert Jason Earle, and we challenge some of the biggest assumptions surrounding mold illness. We unpack why modern homes may be working against our health, why the building itself should be viewed as part of your wellness ecosystem, and why one test can never tell the whole story. If you've been dealing with unexplained symptoms, wondering whether your home could be part of the equation, or simply want to create a healthier environment for yourself and your family, this conversation will completely change the way you think about the place you call home. Visit https://www.gotmold.com/ and use the code Nat10. Dust test link: https://dusttest.gotmold.com/ E-Book - https://www.gotmold.com/ebook-landing-page/ Article he mentioned: https://www.gotmold.com/testing-for-mold-avoid-ermi/?srsltid=AfmBOor_h1U3x5pZnPnHZcC6V4ecKUSnXczMNBtybtaVQrSfkfIHfBPE Episode Timestamps: Introduction: Why Most Mold Tests Miss the Real Problem ... 00:00:00 Why Modern Homes Can Become Health Hazards ... 00:13:00 How Modern Construction Created Health Problems ... 00:17:22 The First Warning Signs Your Home May Be Making You Sick ... 00:21:30 Mold, VOCs & Why New Homes Aren't Always Safer ... 00:24:48 Construction Mistakes That Trap Moisture Inside Walls ... 00:25:37 Why You Should Build a Relationship With Your Home ... 00:28:57 The Dangerous Search for a Single "Perfect" Mold Test ... 00:29:54 What a Proper Mold Assessment Actually Looks Like ... 00:30:35 Why ERMI Can Create False Confidence or Unnecessary Panic ... 00:33:55 Petri Dish Tests: Why Jason Calls Them Junk Science ... 00:35:31 How Outdoor vs. Indoor Mold Should Really Be Compared ... 00:36:56 The Problems With ERMI's Original Design ... 00:39:18 Introducing AI-Powered Dust Testing & the Future of Mold Detection ... 00:44:00 Air Testing vs. Dust Testing: When Each Matters ... 00:46:37 Why Dust Creates a Historical Record of Your Home ... 00:48:42 When Symptoms and Test Results Don't Agree ... 00:51:00 The Nervous System's Role in Mold Illness ... 00:53:17 Confirmation Bias in Mold Testing & Functional Medicine ... 00:57:32 The Most Important Steps for Recovery ... 00:59:24 Our Amazing Sponsors: MitoBlue by Wizard Sciences ? A longevity-focused formula that combines pharmaceutical-grade methylene blue with NMN, PQQ, fisetin, and apigenin to support healthy mitochondria, cellular renewal, and healthy aging. Learn more HERE and use code NAT15 for 15% off. Mitopure Gummies by Timeline ? Supports healthier cellular energy, muscle strength, recovery, and healthy aging with clinically proven Urolithin A?without artificial sweeteners, colors, flavors, or unnecessary fillers. Head to timeline.com/nat20 to get Mitopure starting at just $99 and save an additional 20% on your order. MassZymes by BIOptimizers - A full-spectrum digestive enzyme formula with 4x more protease than leading competitors to help maximize protein digestion and nutrient absorption. Visit bioptimizers.com/bionat and use code BIONAT for 15% off your order plus a free travel-size bottle of MassZymes while supplies last. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

? Please don?t forget to follow my NEW Instagram account at https://www.instagram.com/longevitywithnat/ For years we've talked about longevity as if the answer is hiding in the next supplement, biomarker, or miracle molecule. But what if we've been looking at aging through far too narrow a lens? Today's guest, Dr. Marios Kyriazis, has spent decades challenging that idea by exploring aging through medicine, complexity science, cybernetics, and even philosophy. We unpack what bioregulators actually are, why so much of the conversation around them has become overhyped, and how concepts like hormesis, adaptation, and even our relationship with technology may shape how we age. This is one of those conversations that starts with peptides and ends with a much bigger question: what does it really mean to build a longer, healthier life? Where to find Bioregulators: visit https://profound-health.com/?Aff=Longevity15 and use code NAT15 for 15% off your first order Episode Timestamps: Introduction to Dr. Marios Kyriazis & Rethinking Aging ... 00:00:00 Why Humans Age Differently Than Animals ... 00:06:49 The Role Of Consciousness, Stress & Positive Thinking ... 00:13:19 What Peptide Bioregulators Actually Are ... 00:15:29 Manufacturing, Quality Control & Why Source Matters ... 00:18:24 Carnosine, Natural Extracts & The Origins Of Bioregulators ... 00:19:48 Organ Extracts, Food & Ancient Healing Traditions ... 00:23:20 Natural vs. Synthetic Bioregulators ... 00:26:19 Personalized Medicine & Why One Size Doesn't Fit All ... 00:30:00 Side Effects, Safety & Clinical Experience ... 00:37:01 Professor Cavinson's Research: Why The West Remains Skeptical ... 00:38:32 The Biggest Misconceptions About Bioregulators ... 00:44:22 Cycling Bioregulators & The Principle Of Hormesis ... 00:47:47 How Many Bioregulators Should You Take? ... 00:50:10 Oxidative Stress, Free Radicals & Aging ... 00:51:45 Do Bioregulators Reduce Oxidative Damage? ... 00:54:37 Why Quality Manufacturing Is So Difficult ... 00:57:12 Avoiding Routine As A Longevity Strategy ... 01:07:42 Practical Longevity Advice For Midlife ... 01:11:07 Our Amazing Sponsors: Blue Cannatine by Troscriptions ? Precision-formulated troches designed to support sustained focus and mental clarity, helping you stay sharp through long workdays, recording sessions, travel, and everything in between. Visit troscriptions.com/NATPODCAST or use code NATPODCAST at checkout to save 10% off your first order. Quantum Upgrade ? A 24/7 quantum energy streaming service designed to support energy, focus, sleep, recovery, and a more balanced nervous system, backed by placebo-controlled research showing measurable improvements in stress-related brain activity and heart rate variability. Try it free for 15 days with no credit card required at QuantumUpgrade.io and use code NAT15.  Just Thrive 90-Day Probiotic ? A spore-based probiotic that survives stomach acid to arrive 100% alive in your gut, supporting better digestion, nutrient absorption, immunity, and less bloating. Start your first 90-day subscription today and you'll get a FREE 90-day supply of Digestive Bitters (a $90 value) to help optimize digestion and support healthy appetite regulation. Click HERE to learn more. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

? Please don?t forget to follow my NEW Instagram account at https://www.instagram.com/longevitywithnat/ If you've been hearing everyone talk about exosomes but still aren't exactly sure what they are?or whether they're actually worth the hype?this episode is for you. Today I'm joined once again by Amitay Eshel and Anastasia Khodzhaeva from Young Goose to separate the science from the marketing and unpack what exosomes are really doing inside your skin. We explore why your skin may be the most honest reflection of your biological age, how mitochondrial health and cellular repair influence the way you age, and why not all exosome products are created equal. We also get into the future of longevity skincare, formulation science, and what consumers should actually be looking for before spending money on the latest trend. Special Young Goose Offer: Click HERE and use code NAT10 to save on Young Goose products! Links to previous episode: #381: Better Than Lasers: NAD+, Spermidine, and Methylene Blue for Youthful Skin | Amitay Eshel and Anastasia Khodzhaeva #209: How to Reverse The Aging Process Without Long Term Damage with Amitay Eshel #118: Our Skin is a Mirror: Why Skin Health is a Marker of Overall Health #71: How to Boost the Effects of Anti-Aging Skincare and Light Therapy Episode Timestamps: Introduction & Returning Guests ... 00:00:00 Why Skin May Be Your Most Honest Longevity Biomarker ... 00:08:52 Gut Health, Mitochondria & What Your Skin Reveals ... 00:14:15 Biological Age vs Chronological Age ... 00:19:08 Performance, Longevity & Resilience: Three Ways to Think About Aging ... 00:21:34 The Exosome Revolution: What Are Exosomes? ... 00:30:18 Why Most Consumers Ask the Wrong Questions About Exosomes ... 00:34:08 Platelet vs Stem Cell Exosomes Explained ... 00:38:03 Why Formulation Matters More Than Marketing ... 00:43:51 How Young Goose Built Their Exosome Formula ... 00:52:28 Formulation Science vs The Next "Miracle Ingredient" ... 00:59:21 Where Longevity Skincare Is Headed Next ... 01:08:48 Final Thoughts & Young Goose Discount Code ... 01:14:06 Our Amazing Sponsors: Manukora Honey ? A delicious real-food source of prebiotics, Manukora's high-MGO Manuka honey helps support your gut microbiome, digestion, and immune health with just one teaspoon a day. Head to MANUKORA.com/NAT to save up to 31% plus receive $25 worth of free gifts with the Starter Kit. Electrolyze by BEAM Minerals - Electrolyze is a plant-based fulvic mineral formula that delivers a full spectrum of highly bioavailable trace minerals and electrolytes to support hydration, nutrient delivery, and cellular energy. Head to beamminerals.com/NAT20, use code NAT20, and get 20% off your first order. Grass-Fed Whey Protein by Puori - A third-party tested, grass-fed whey protein delivering 21g of protein per serving, with every batch tested for over 200 contaminants and results available via a QR code for complete transparency. Head to puori.com/nat and use code NAT20 to get 32% off your first subscription order, plus a free premium shaker bottle. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

? Please don?t forget to follow my NEW Instagram account at https://www.instagram.com/longevitywithnat/ Today, I?m joined by the insightful Dr. Scott Sherr, a pioneer in health optimization and mitochondrial medicine. In our conversation, Dr. Sherr introduces his groundbreaking concept?the "sympathetic spiral of doom"?and explains why so many high performers end up burned out, frustrated, and feeling like their nervous systems are working against them. Give it a try at https://troscriptions.com/NATPODCAST or enter NATPODCAST at checkout for 10% off. Cannot be combined with any other offers. Episode Timestamps: Welcome and Introduction ... 00:00:00 Dr. Scott Sherr and the "Sympathetic Spiral of Doom" ... 00:00:42 Aging, Stem Cells, and Repair Strategies ... 00:01:21 Defining and Observing the Spiral in Practice ... 00:05:07 Mitochondrial Dysfunction and Chronic Stress ... 00:08:11 Why Rebuilding Energy Must Come First ... 00:12:00 High Performers, Burnout, and Overdoing Recovery ... 00:15:14 Symptoms and Effects of Burnout ... 00:16:30 Evaluating Energy, Metabolic Health, and Daily Stress ... 00:18:25 Methylene Blue: Immediate Mitochondrial Support ... 00:20:54 Clarifying: Not Stimulants, True Cellular Support ... 00:14:07 Differentiating Healthy Stress from System Overload ... 00:24:06 Oscillation Between Stress and Recovery ... 00:25:10 Signs You're Stuck in Chronic Sympathetic Mode ... 00:29:01 Sequence for Recovery: Energy, GABA, Immune, Sleep ... 00:54:06 Recognizing Progress and Returning to Capacity ... 01:00:44 Key Considerations for Methylene Blue ... 01:09:50 Anti-Aging, Recovery, and the Parasympathetic Edge ... 01:14:14 Our Amazing Sponsors: Stemregen - A daily formula designed to support your body?s natural repair systems by helping release your own stem cells into circulation, supporting recovery, resilience, and whole-body renewal at the source. Visit stemregen.co/NAT15 and use code NAT15.  MassZymes by BIOptimizers - A full-spectrum digestive enzyme formula with 4x more protease than leading competitors to help break down protein more efficiently so your body can actually use the amino acids you're eating. Head to bioptimizers.com/bionat and use code BIONAT for 15% off your order plus a free travel-size bottle of MassZymes (a $20 value) while supplies last. Vita Zero-Age Exosomes by Vitali Skincare ? a regenerative ?stacking? formula with exosomes, GHK-Cu, niacinamide, and glutathione designed to support your skin at a cellular level rather than just the surface; go to www.vitaliskincare.com/?ref=Nat20 and use code NAT20 for 20% off. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

Today, I?m joined by Dr. Teo Soleymani, a renowned dermatological oncologist whose unique vantage point bridges the worlds of conventional medicine and longevity science. As someone who sees the real consequences of UV damage in his surgical practice while also advocating for a balanced, evidence-driven approach to sunlight and skin health, Dr. Teo Soleymani isn?t afraid to challenge the most entrenched ideas in modern skincare. Listeners of this podcast can receive 15% off* of SunPowder when you go to drinksunpowder.com/NAT15 *Not available in combination with subscribe and save discount. Episode Timestamps: Podcast introduction and overview ... 00:00:00 Dr. Solemani?s clinical experience bridging conventional and wellness dermatology ... 00:05:18 Changing attitudes on sunlight: risks, benefits, and backlash ... 00:10:29 Genetic vs. environmental factors in skin cancer ... 00:11:22 Industry influence and cosmeceutical marketing in dermatology ... 00:12:28 Tan myths, burning, and the science of sun exposure ... 00:23:27 Sun ?callus? and strategies for building UV tolerance ... 00:34:11 How to personalize safe sun exposure using minimal erythema dose (MED) ... 00:41:49 Best practices for sunscreen use and types to choose ... 00:43:54 Emergence of personalized and precision dermatology ... 00:51:04 Peptides: GHK-Cu, topical vs. injectable, and the science gap ... 00:56:03 Melanotan dangers and why to avoid ... 01:07:44 Innovations in oral skin protection?Sunpowder supplement ... 01:13:12 Sunpowder?s evidence, mechanism, and role as internal support ... 01:15:30 Smart sun practices, rapid-fire advice, and sign-off ... 01:24:01 Our Amazing Sponsors: Qualia NAD+ by Qualia Life ? Clinically proven to increase NAD+ levels by an average of 67% in just four weeks, Qualia NAD+ uses three highly bioavailable precursors to support cellular energy, mental clarity, metabolism, and healthy aging. Visit qualialife.com/nathalie and use code NAT C.A.R.E. Mitochondrial Moisturizer by Young Goose ? An upgraded cellular skincare formula featuring Methylene Blue and Liposomal Creatine to support mitochondrial function, skin barrier health, and resilient, hydrated skin. Click HERE and use code NAT10 to save on C.A.R.E. Mitochondrial Moisturizer. Nature's Marvels Bioregulators by Profound Health - Natural bioregulators designed to support your body's own cellular communication and healthy aging, with targeted formulas for everything from brain and immune health to sleep and vitality. Click here and use code NAT15 for 15% off your first order. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

Today, I?m joined by Alex Kikel?a name that?s become synonymous with pushing the frontiers of biology, performance, and healing. Alex is the kind of person who, when told ?there?s nothing more we can do,? responds with, ?but what if that?s not true?? In our conversation, he shares the pivotal moments that made him question everything about the standard approach to health, including his personal story of reversing serious conditions when traditional solutions failed. Episode Timestamps: Introduction to podcast vision and focus ... 00:00:00 Importance of foundational practices before advanced interventions ... 00:07:15 Overlooked basics in cancer and chronic disease: oxygen and CO2 ... 00:08:28 Power of mindset and plasticity in overcoming illness ... 00:11:27 Limits of the medical model and need for new frameworks ... 00:13:24 Pattern recognition: side effect tracking over diagnosis ... 00:15:05 TBI, brain healing: ketones, hydrogen, and personalized support ... 00:17:08 Brain fuel sources and stacking for neurorecovery ... 00:19:26 Dosing lessons from experimentation and case tracking ... 00:23:00 BPC157 reactions and bioindividuality ... 00:27:08 Hormones, mitochondria, and interconnected healing systems ... 00:38:33 HRT for women vs. men?different challenges and approaches ... 00:39:40 Microtubules, consciousness, and upstream healing ... 00:43:28 Mitochondrial peptides: dosing, overspin, and autoregulation ... 00:45:25 Cautions before peptides: effective second-tier supplements ... 00:55:44 Sulforaphane: clinical power and person-specific cautions ... 00:57:29 Neurodegeneration: combining fueling, signaling, and inflammation ... 01:02:16 Disuse and under-stimulation as causes of brain aging ... 01:06:48 Movement, oxygen use, and patterns in chronic disease ... 01:09:10 Treading the line between innovation and risk ... 01:11:20 Challenging lipid dogma; focus on oxidation/mitochondria ... 01:14:17 True longevity as fit span and living well ... 01:15:51 Most impactful change: invest in relationships ... 01:16:26 Our Amazing Sponsors: LongeFera by Regenerive?- A precision-formulated ashwagandha supplement that isolates four key bioactive compounds to support a healthy stress response, cognitive function, balanced inflammation, and cellular longevity?without the fillers and inconsistent extracts found in many products. Head to regenerive.co and use code NAT25 for 25% off your order. Wolverine Formula by LVLUP Health ? A peptide-based formula designed to support recovery, tissue repair, and musculoskeletal health, helping your body bounce back from workouts and everyday wear and tear. Click HERE and use code NAT for 15% off your order. Mitopure Gummies by Timeline ? Supports healthier cellular energy, muscle strength, recovery, and healthy aging with clinically proven Urolithin A?without artificial sweeteners, colors, flavors, or unnecessary fillers. Head to timeline.com/NAT20 to get Mitopure starting at just $99 and save an additional 20% on your order. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

Today, I?m joined once again by the innovative Ian Mitchell, a name familiar to anyone passionate about radical longevity, biohacking, and pushing the boundaries of human performance. In this conversation, Ian pulls back the curtain on the science and surprising applications of C60?known as the ?buckyball? molecule?and why it?s become such a powerful tool for both peak performance and healthy aging. Click HERE and use code NAT15 for 15% off Ian?s amazing formulations Previous Episodes: #287: Ian Mitchell: Unlocking Longevity: The Power of Energy and Oxygen #329: How C60 Is Changing Aging: Energy, Brain Health, and Recovery Insights With Ian Mitchell #172: Wizard Sciences: Biohacking for Peak Performance with C60 Episode Timestamps: Introduction and podcast mission ... 00:00:00 C60 discovery and properties ... 00:04:34 Industrial vs. health applications of C60 ... 00:05:23 C60 rat study and insights on longevity ... 00:13:41 Human and animal C60 experiences ... 00:17:30 C60 supplementation dosing strategies ... 00:21:06 Muscle fiber recruitment and athletic benefits ... 00:24:51 Formulation differences: oil types and targeted effects ... 00:27:10 Stepwise approach to inflammation and brain support ... 00:29:06 Compounds added to C60 products (NMN, CoQ10, etc.) ... 00:33:28 C60 and neurodegeneration mechanisms ... 00:48:55 EMFs, neural inflammation, and mitigation ... 00:53:30 Optimal dosing and why cycling C60 matters ... 01:00:57 Emerging research: stem cells and diabetes ... 01:02:53 Where to find C60 and additional resources ... 01:10:01 Our Amazing Sponsors: Blue Cannatine by Troscriptions ? Combining methylene blue with carefully selected nootropics in a fast-acting troche, Blue Cannatine helps support concentration, productivity, and flow-state performance whether you're working, creating, or tackling a demanding day. Give it a try at troscriptions.com/NATPODCAST or enter NATPODCAST at checkout for 10% off your first order. (Not valid when combined with other offers) O?RACLE by Wizard Sciences ? A daily ozonated oil capsule designed to support immune balance, cellular communication, and antioxidant production without clinics, machines, or complicated routines; Click HERE and use code NAT15 for 15% off. Daily Gut Detox by Just Thrive Health ? A science-backed detox powered by clinically proven immunoglobulins that bind and remove toxins while supporting your gut, immune system, and digestion?without harsh flushing or discomfort. Visit JustThriveHealth.com/NAT20 and use code NAT20 for 20% off your order, risk-free. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

Today, I?m joined by Nicole Bell, an accomplished engineer who made an unexpected leap from designing cutting-edge surgical robotics to becoming a powerful advocate for better diagnostics in tick-borne diseases. Nicole?s story is both deeply personal and urgent: after her husband was misdiagnosed with early-onset Alzheimer?s?only to later discover the true culprit was hidden tick-borne infections?she set out to uncover why our medical system misses these subtle yet devastating conditions. Episode Timestamps: Podcast introduction and episode overview ... 00:00:00 Subtle early signs?normalization and mood changes ... 00:10:16 Challenges with standard diagnostic routines ... 00:14:59 Common misconceptions: bullseye rash and antibiotics ... 00:17:06 Prevalence and misdiagnosis of Lyme and co-infections ... 00:18:01 How pathogens evade detection in humans ... 00:20:20 Broader vectors: fleas, lice, and pets ... 00:23:11 Complexity of co-infections (Lyme, Bartonella, Babesia) ... 00:29:39 When to suspect vector-borne disease?key symptom clusters ... 00:31:58 Infections and neurodegeneration: why the link is resisted ... 00:38:01 Evidence of pathogens in brain tissue from research ... 00:42:21 Hope for innovation and better diagnostics ... 00:51:20 New testing technologies and patient self-advocacy ... 00:54:40 Major insights from the state of Lyme research ... 01:02:51 Overcoming myths and regional biases ... 01:07:23 Advice for caregivers and rethinking health ... 01:13:12 Practical steps for prevention and early detection ... 01:17:53 Our Amazing Sponsors: STEMREGEN by Stemregen - A daily formula designed to support your body?s natural repair systems by helping release your own stem cells into circulation, supporting recovery, resilience, and whole-body renewal at the source. Visit stemregen.co/NAT15 and use code NAT15. https://stemregen.co/NAT15 Blue Cannatine by Troscriptions ? A precision-formulated troche featuring methylene blue, nicotine, caffeine, and CBD designed to support focus, mental clarity, and sustained cognitive performance without the typical jitters or crash. Give it a try at troscriptions.com/NATPODCAST or enter NATPODCAST at checkout for 10% off your first order. CP1 Pure Collagen Peptides by Puori ? a clean, unflavored collagen that supports connective tissue, joints, and skin elasticity with a unique amino acid profile your body actually uses, plus full third-party testing; go to puori.com/NAT and use code NAT for 32% off when you start a subscription. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

Today, I?m sitting down with the trailblazing Dr. Tyna Moore, a pioneer in reframing the conversation around GLP-1 medications. Instead of focusing solely on weight loss, Dr. Moore reveals how these powerful molecules can open a critical window to reset our health story?if we?re willing to harness that opportunity wisely. Episode Timestamps: Welcome, host introduction, and overview ... 00:00:00 Stigma, marketing, and confusion around GLP-1 use ... 00:05:38 True microdosing vs. standard dosing explained ... 00:08:18 Strength training as essential during GLP-1 therapy ... 00:12:06 GLP-1 medications as windows of opportunity for health resets ... 00:13:24 Risks of extreme thinness and frailty for longevity ... 00:15:11 Why metabolic health matters at every age ... 00:20:56 PCOS renamed as a metabolic disease ... 00:26:07 Senescence, exercise, and aging ... 00:28:10 Dr. Tyna Moore?s GLP-1 research and patient findings ... 00:30:34 GLP-1s reveal deeper metabolic issues ... 00:37:28 Differentiating semaglutide, tirzepatide, retatrutide ... 00:39:41 Liver fat, lean mass loss, and weight regain challenges ... 00:43:59 Personalized dosing, side effects, and patient variability ... 00:46:53 Digestive health, SIBO, and supporting GLP-1 users ... 00:52:37 Lab monitoring and practical implementation ... 01:01:04 Immune impacts, senescence, and metabolic improvements ... 01:02:29 Lifestyle first: exercise, peptide stacking, and fundamentals ... 01:10:49 Cautious optimism for the future of GLP-1s ... 01:12:08 Our Amazing Sponsors: Bioregulators by Nature?s Marvels - targeted peptides designed to support cellular signaling and renewal across key systems like circadian rhythm, immune function, and vascular health as part of a foundational longevity stack; click here and use code NAT15 for 15% off your first order.  Vita Zero-Age Exosomes by Vitali Skincare ? a regenerative ?stacking? formula with exosomes, GHK-Cu, niacinamide, and glutathione designed to support your skin at a cellular level rather than just the surface; go to www.vitaliskincare.com/?ref=Nat20 and use code NAT20 for 20% off. MassZymes by BiOptimizers ? A full-spectrum digestive enzyme formula with 4x more protease to help break down protein into usable amino acids so your body actually benefits from what you eat?try it risk-free with a 365-day money-back guarantee and save 15% at bioptimizers.com/bionat with code BIONAT. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

Today, I?m joined by Zack Abbott, a biotech innovator who took an unconventional path?from pharmaceutical science to the front lines of consumer health. Instead of following the well-worn route of drug development, Zack set his sights on bringing cutting-edge biotechnology directly to people, creating products designed not just for convenience, but for genuinely transforming our relationship with microbiology. Anyone who uses code NATNIDDAM will get 10% off their first order! Visit https://zbiotics.com/NATNIDDAM. Episode Timestamps: Podcast introduction and host background ... 00:00:00 Consumer impact versus traditional drug industry ... 00:06:06 Gap and opportunity for biotech in consumer space ... 00:06:42 Engineered probiotics: not hacks but new relationships with biology ... 00:07:19 Scientific and public responses to engineered probiotics ... 00:09:03 Technology behind genetically engineered probiotics explained ... 00:17:39 Bacillus subtilis: why it?s the ideal delivery vehicle ... 00:27:08 Sugar-to-fiber product mechanism and rationale ... 00:32:58 Importance of fiber quantity and diversity for gut health ... 00:42:26 Sugar-to-fiber: capabilities and limitations ... 00:54:06 Keto/carnivore implications and who benefits from sugar-to-fiber ... 00:57:51 Misunderstandings and realities about GMOs in consumer biotech ... 01:00:02 Regulation, safety, and honest claims in biotech supplements ... 01:07:01 Current science and future of the microbiome in longevity ... 01:12:14 Personalization, AI, and microbiome-directed health ... 01:13:10 Our Amazing Sponsors: MitoQ Hormonal Metabolic Control ? A targeted formula designed to support women through the hormonal and metabolic shifts of perimenopause and menopause, featuring S-Equol for healthy estrogen signaling, B. breve to support the gut-hormone connection, and chromium to help maintain healthy blood sugar balance. Head to MitoQ.com/nat and use code NAT10 to try it for yourself. Manukora Honey - A simple upgrade to your daily routine, this Manuka honey delivers antioxidants, prebiotics, and naturally occurring MGO that you won?t get from regular sweeteners; head to manukora.com/NAT to save up to 31% plus $25 in free gifts with the Starter Kit. http://manukora.com/nat Ultimate GI Repair by LVLUP Health ? a research-backed blend of peptides, zinc carnosine, and gut-support compounds designed to strengthen your gut lining, improve digestion, and support resilience from the inside out; head to lvluphealth.com and use code NAT for 15% off Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

Today, I?m joined by Dr. Robin Rose, a double board-certified gastroenterologist and internal medicine physician who has become a true pioneer in the space of functional and precision medicine. Driven by a relentless curiosity that survived even the most rigid medical training, Dr. Rose shares how her quest to answer ?why? led her beyond conventional medicine into root-cause healing, patient-centered care, and the world of gut health, biochemistry, and the microbiome. Episode Timestamps: Show introduction and host background ... 00:00:00 Early skepticism of conventional GI protocols ... 00:04:30 Embracing probiotics, nutrition, and functional medicine ... 00:05:26 Medical education?s gaps in microbiome and nutrition ... 00:06:12 Critique of diagnosis-driven, algorithmic medicine ... 00:09:39 Leaving conventional practice for holistic, systems biology ... 00:10:12 The body as an interconnected ecosystem ... 00:15:31 Microbiome, mitochondria, immune interplay ... 00:17:53 Chronic illness and the failure of ?one size fits all? protocols ... 00:19:26 Gut-brain-immune axis and its health implications ... 00:22:09 Gut-driven neurodegeneration, mood, and immunity ... 00:24:07 Long Covid: definitions and persistence ... 00:29:29 Spike protein?s toxic role in long Covid and aging ... 00:30:27 Viral, vaccine, and bacterial factors in ongoing disease ... 00:33:04 Diagnostics, individualized protocols, and new treatments ...00:44:54 Prevention and recovery: gut, spike, and diet strategies ... 00:52:52 Daily recommendations and practical steps for longevity ... 01:02:07 Quick-fire gut health myths and personal insights ... 01:07:45 Where to find Dr. Robin Rose and episode wrap-up ... 01:10:09 Our Amazing Sponsors: Mitopure Gummies by Timeline - These clinically researched gummies support mitophagy to help renew your mitochondria and boost cellular energy, giving you a stronger biological foundation for resilience?visit timeline.com/nat20 to get 20% off. Apollo Neuro ? A wearable nervous system support device that uses personalized SmartVibes technology to help you feel calmer, more focused, and better able to shift into rest mode without adding another complicated wellness routine. Head to apolloneuro.com/NAT and use code NAT for $99 off and 1 year Smart Vibes Ai. Vampire Exosome by Young Goose - A next-generation serum packed with three trillion PRP-derived exosomes and RejuvNAD to support collagen production and skin renewal at the cellular level?helping results build over time instead of fading fast. Click HERE and use code NAT10 Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

Today, I?m joined by Dr. Andrew Salzman, a pioneer in NAD research whose work has spanned everything from pediatric sepsis to cutting-edge longevity science. Dr. Salzman dives deep into why NAD isn?t just another supplement buzzword, but a central molecule powering our energy, resilience, and even fertility. Wonderfeel is gifting a 7-day Youngr? supply with every Youngr? order. Click here and use code NAT at checkout to claim your complimentary gift. Offer ends two weeks from today?s episode. Episode Timestamps: Introduction ... 00:00:00 Scientific rigor in supplement development ... 00:06:49 Evolution of medicine and the role of populist health ... 00:09:37 Changing views on aging and longevity ... 00:14:13 NAD?s role in energy, repair, and aging ... 00:17:22 When NAD starts to decline and why it matters ... 00:21:06 Early signs of NAD deficiency ... 00:22:22 NAD?s connection to fertility and reproductive health ... 00:25:03 Gut health, inflammation, and NAD depletion ... 00:34:16 Lifestyle and diet drivers of NAD loss ... 00:39:35 How to assess NAD needs ... 00:42:11 Boosting NAD: supplement strategies and limits ... 00:44:09 NMN versus NR and dosing ... 00:46:05 Wonderfeel?s approach: address depletion and boost levels ... 00:51:53 Commonly reported results and user feedback ... 00:54:52 Creatine?s critical role in cellular energy and aging ... 00:57:55 Future directions: criticism, biomarkers, and personalization ... 01:10:10 Podcast wrap-up, offers, and disclaimer ... 01:15:09 Our Amazing Sponsors: Quantum Upgrade ? A 24/7 quantum energy streaming service designed to support energy, focus, sleep, recovery, and a more balanced nervous system, backed by placebo-controlled research showing measurable improvements in stress-related brain activity and heart rate variability. Try it free for 15 days with no credit card required at QuantumUpgrade.io and use code NAT15. Micro-BOOST (Humic Mineral Complex) by BEAM Minerals - A concentrated liquid humic formula that binds and removes toxins like heavy metals, mold, and pollutants?working fast with just a daily shot. Head to http://www.beamminerals.com/NAT20, use code NAT20, and get 20% off your first order. Daily Gut Detox by Just Thrive Health ? A gentle, science-backed detox powered by clinically proven immunoglobulins that bind and remove toxins while supporting your gut, immune system, and digestion?without harsh flushing or discomfort. Visit JustThriveHealth.com/NAT20 and use code NAT20 for 20% off your order, risk-free. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

Today, I?m joined by the inspiring Dr. Anshul Gupta, a conventionally trained family physician who completely reimagined thyroid care after his own life and health hit a breaking point. Dr. Gupta shares how his battle with fatigue, weight gain, and relentless gut pain led him down a path beyond prescriptions, ultimately transforming his personal health and medical practice. Through functional medicine, he found a way out of his own struggle?and uncovered what so many thyroid patients are missing. Episode Timestamps: Welcome and episode introduction ... 00:00:00 Thyroid care gaps and Hashimoto?s paradigm shift ... 00:07:05 Understanding Hashimoto?s and why levothyroxine often falls short ... 00:08:24 Comprehensive thyroid testing and antibody significance ... 00:14:34 Hashimoto?s as an autoimmune gateway and risk escalation ... 00:16:00 The five root causes of Hashimoto?s ... 00:17:15 Chronic infections, spike protein, and immune activation ... 00:21:21 Food?s impact: diet strategy and common dietary pitfalls ... 00:27:01 A three-step framework to reverse Hashimoto?s ... 00:43:44 Practical challenges, especially stress management ... 00:48:00 Peptides and bioregulators: clinical use and observations ... 00:50:09 GLP-1 agonists: thyroid risks and benefits ... 00:58:36 Transformative patient story ... 01:00:48 Thyroid?s centrality to longevity and early testing advice ... 01:03:33 Family support and final resources ... 01:10:09 Our Amazing Sponsors: Tro Zzz by Troscriptions ? A fast-acting sleep troche that dissolves in your cheek and combines melatonin with compounds like honokiol, adenosine, cordycepin, CBD, CBN, and 5-HTP to support deep, restorative sleep when travel, stress, or late workouts throw things off. Give it a try at troscriptions.com/NATPODCAST or enter NATPODCAST at checkout for 10% off your first order. O?RACLE by Wizard Sciences ? A daily ozonated oil capsule designed to support immune balance, cellular communication, and antioxidant production without clinics, machines, or complicated routines; learn more at wizardsciences.com and use code NAT15 for 15% off. Bioregulators by Nature?s Marvels - targeted peptides designed to support cellular signaling and renewal across key systems like circadian rhythm, immune function, and vascular health as part of a foundational longevity stack; head to http://www.profound-health.com/?Aff=Longevity15 and use code NAT15 for 15% off your first order. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

Today, I?m joined by the incredibly insightful Donna Jackson Nakazawa, a science journalist and bestselling author whose work bridges the worlds of neuroscience, storytelling, and personal transformation. Donna has a unique gift for translating complex brain science into real-life strategies?and she?s not afraid to weave in her own powerful journey, from childhood trauma and autoimmune challenges to her fierce quest for hope and healing. Episode Timestamps: Podcast introduction and episode overview ... 00:00:00 Chronic stress, childhood adversity, and lifelong health ... 00:07:04 Microglia as the link between stress and brain changes ... 00:10:47 Protector vs destroyer: microglia?s dual role in the brain ... 00:11:21 Neuroplasticity and hope for healing at any age ... 00:15:19 Modern stressors and impacts on kids? brain health ... 00:17:25 Safety, rumination, and reshaping the brain?s wiring ... 00:18:22 Donna?s personal journey with trauma and autoimmune illness ... 00:38:00 How to break rumination: the MIST framework ... 00:47:40 The science and power of language on health ... 01:01:00 Daily practice tips to disrupt negative thought cycles ... 01:07:26 Rethinking longevity: focus on healthspan and connection ... 01:10:03 How to preorder the book and connect online ... 01:11:38 Podcast outro and disclaimer ... 01:13:02 Our Amazing Sponsors: Ultimate GI Repair by LVLUP Health ? a research-backed blend of peptides, zinc carnosine, and gut-support compounds designed to strengthen your gut lining, improve digestion, and support resilience from the inside out; head to lvluphealth.com and use code NAT for 20% off MassZymes by BiOptimizers ? A full-spectrum digestive enzyme formula with 4x more protease to help break down protein into usable amino acids so your body actually benefits from what you eat?try it risk-free with a 365-day money-back guarantee and save 15% at bioptimizers.com/bionat with code BIONAT. Vita Zero-Age Exosomes by Vitali Skincare ? a regenerative ?stacking? formula with exosomes, GHK-Cu, niacinamide, and glutathione designed to support your skin at a cellular level rather than just the surface; go to www.vitaliskincare.com/?ref=Nat20 and use code NAT20 for 20% off. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

Today, I?m joined by Dr. William Davis, a cardiologist-turned-gut detective and bestselling author behind Wheat Belly, Super Gut, and Super Body. In this episode, Dr. Davis breaks down what it really means to have youthful, functional muscle, why maintaining the muscle of your 20s and 30s is about so much more than hitting the gym, and how missing microbes?like L. reuteri?might be the secret to restoring your strength and energy. Previous Episodes:  #330: Lose the Bloat, Fix Your GUT: Inside the Microbiome Revolution (Skin, Weight & Longevity Secrets) with Dr William Davis Episode Timestamps: Welcome, host and episode introduction ... 00:00:00 What is youthful, functional muscle? ... 00:04:40 Antibiotics, gut microbes, and aging ... 00:07:14 Microbiome?s link to inflammation and mood ... 00:09:31 How gut dysfunction drives disease ... 00:11:07 Conventional medicine?s blind spot and SIBO ... 00:15:26 Testing for SIBO and its prevalence ... 00:21:49 ?Microbe-driven? muscle & SIBO yogurt fermentation ... 00:24:17 Why fermented foods and keystone microbes matter ... 00:28:11 GLP-1 obesity drugs: risks and rebound ... 00:31:17 Extreme dieting and lasting metabolic effects ... 00:37:04 From cardiology to gut health: Dr. Davis?s journey ... 00:40:30 DIY approaches for restoring health ... 00:45:05 Modern diet pitfalls vs. ancestral eating ... 00:46:42 L. reuteri, oxytocin, and muscle growth ... 00:53:00 How to start and troubleshoot SIBO yogurt ... 01:01:39 Practical 30-day protocol for vitality ... 01:09:22 Episode wrap-up and thanks ... 01:18:42 Our Amazing Sponsors: Vampire Exosome by Young Goose - A next-generation serum packed with three trillion PRP-derived exosomes and RejuvNAD to support collagen production and skin renewal at the cellular level?helping results build over time instead of fading fast. CLICK HERE and use code NAT10. Apollo Neuro ? A wearable nervous system support device that uses personalized SmartVibes technology to help you feel calmer, more focused, and better able to shift into rest mode without adding another complicated wellness routine. Head to apolloneuro.com/nat and use code NAT for $99 off and 1 year Smart Vibes Ai. MitoPure Gummies by Timeline: These clinically researched gummies support mitophagy to help renew your mitochondria and boost cellular energy, giving you a stronger biological foundation for resilience?visit timeline.com/nat20 to get 20% off. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

Today, I?m joined by Kyal Van Der Leest, an innovative naturopath, nutritionist, and founder of LVLUP Health, whose formulas are changing the way we think about effective supplementation. Kyal?s journey is deeply personal: from caring for his mother through a long battle with cancer, to overcoming his own intense health struggles with mold illness. These experiences led him to push past superficial fixes and dig deep into what really works for healing and optimizing the body. Visit www.lvluphealth.com and use code NAT for 20% off Previous Episodes:  Episode #116: Does the Perfect Gut Supplement Exist? Episode #148: Kyal Van Der Leest: Liver Health, Gut Health, and Detoxification #326: From Brain Fog to Focus: Techniques and Supplements to Enhance Cognitive Function With Kyal Van Der Leest Episode Timestamps: Welcome & Podcast intro ... 00:00:00 Pitfalls of cheap supplements & importance of quality ... 00:05:33 Mistakes: symptom chasing, green allopathy, and root causes ... 00:07:38 Blending naturopathy, biochemistry, and biohacking ... 00:10:26 Choosing peptides, herbs, or vitamins for target outcomes ... 00:16:43 Synergy, proprietary blends, and dosing transparency ... 00:18:06 Understanding supplement forms, dosages, and stack simplification ... 00:24:29 Root cause thinking: brain fog, labs, and interconnected symptoms ... 00:34:16 Dopamine, focus, and the risks of overstimulation ... 00:39:59 Peptides in brain health?a step beyond herbs or nutrients ... 00:43:00 Short-term nootropics vs. long-term investments in brain health ... 00:46:17 Longevity levers: muscle, blood sugar, and blood flow ... 00:51:04 Blood sugar regulation?berberine, dihydroberine, and alternatives ... 00:53:32 Liver?s core role in hormones and energy ... 00:55:59 Heart and lung health?peptides, circulation, and overlooked systems ... 01:00:10 Peptides vs. herbs?when to choose and when to avoid ... 01:04:21 Future of peptides, supplement quality, and industry direction ... 01:07:45 Hierarchy: Foundations before biohacks ... 01:08:57 Simple, high-impact upgrade picks & final advice ... 01:11:17 Industry trends, influencer issues, and episode wrap ... 01:17:01 Where to find Kyal and promo code details ... 01:19:19 Our Amazing Sponsors: Sunlighten: Up to $2,100 off + FREE shipping Sunlighten Sauna - Looking to support your recovery and calm your nervous system? Sunlighten offers full spectrum infrared saunas?compact enough for real homes, powerful enough to support detoxification, mitochondrial energy, and a smarter longevity routine. Visit get.sunlighten.com/natpodcast and use code natlongevity to get $2,100 off + FREE shipping. Apollo Neuro ? A wearable nervous system support device that uses personalized SmartVibes technology to help you feel calmer, more focused, and better able to shift into rest mode without adding another complicated wellness routine. Head to apolloneuro.com/nat Offer to receive 20% off. Vampire Exosome by Young Goose - A next-generation serum packed with three trillion PRP-derived exosomes and RejuvNAD to support collagen production and skin renewal at the cellular level?helping results build over time instead of fading fast. Shop at younggoose.com and use code NAT10. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

Today, I'm joined by Dr. Taz Bhatia, a trailblazing integrative medicine physician, entrepreneur, and leading voice in women's health and longevity. In our conversation, Dr. Taz opens up about how her personal health challenges as a conventionally-trained MD led her to explore nutrition, Chinese medicine, and Ayurveda, inspiring her to reimagine what it means to truly care for the whole person. We also dive into the work of Countdown, a nonprofit accelerating mitochondrial science and medicine to improve how we prevent and treat disease. If you?re interested in women?s health, functional medicine, healthy aging, and cellular energy, this episode is packed with valuable insights. Episode Timestamps: Introduction to Longevity Podcast and host ... 00:00:00 Introducing Dr. Taz Bhatia and Countdown?s mission ... 00:01:10 Limitations of conventional medicine and time with patients ... 00:08:03 Holistic approach: importance of deep intakes and history ... 00:10:09 Cellular energy and why it matters now ... 00:11:38 Modern lifestyle threats to cellular and mitochondrial health ... 00:12:27 Rising chronic inflammation and age-related diseases ... 00:13:05 Missed opportunities: not measuring or prioritizing cell health ... 00:14:01 Inherited and childhood mitochondrial issues ... 00:15:13 Impact of earlier mitochondrial research on current medicine ... 00:20:12 Manifestations of mitochondrial aging in elderly and kids ... 00:22:15 Women?s health: chronic stress, hormone decline, and autoimmunity ... 00:26:40 Risks of hormone treatment without cell health basics ... 00:37:41 Underfunding of women?s health research and its clinical impact ... 00:40:34 Mitochondria?s direct link to hormone and overall health ... 00:45:02 Countdown: accelerating mitochondrial research and awareness ... 00:46:16 Ovarian aging?s role in female longevity ... 00:48:02 Future of medicine: better testing, integration, and support ... 00:54:55 Our Amazing Sponsors: Tro Zzz by Troscriptions ? A fast-acting sleep troche that dissolves in your cheek and combines melatonin with compounds like honokiol, adenosine, cordycepin, CBD, CBN, and 5-HTP to support deep, restorative sleep when travel, stress, or late workouts throw things off. Head to troscriptions.com and use code NAT10 for 10% off your first order. Bioregulators by Nature?s Marvels - targeted peptides designed to support cellular signaling and renewal across key systems like circadian rhythm, immune function, and vascular health as part of a foundational longevity stack; head to profound-health.com/?Aff=Longevity15 and use code NAT15 for 15% off your first order. O?RACLE by Wizard Sciences ? A daily ozonated oil capsule designed to support immune balance, cellular communication, and antioxidant production without clinics, machines, or complicated routines; learn more at wizardsciences.com and use code NAT15 for 15% off. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

Today, I?m flying solo to tackle a topic that?s essential for anyone invested in their health: how to truly vet your supplements. With new products hitting the shelves daily and wellness marketing louder than ever, it?s easy to get swept up in the latest hype?but more isn?t always better, and sometimes it can actually make things worse. Episode Timestamps: Welcome and podcast introduction ... 00:00:00 Baseline biomarker testing before supplementing ... 00:04:21 Risks with supplementing without testing ... 00:06:06 Third-party certification for supplement quality ... 00:08:18 Supplement contamination issues ... 00:08:55 Seals to look for and their limits ... 00:09:54 Efficacy and scientific evidence hierarchy ... 00:10:53 Limitations of animal/cell data vs. human trials ... 00:13:05 Red flags in supplement marketing ... 00:15:12 "Natural" isn?t always safe?drug interactions and toxicity ... 00:15:58 Fat-soluble vitamin risks and safe disclosure ... 00:18:12 Form and bioavailability importance ... 00:21:07 Optimal vs. poor supplement forms ... 00:21:25 Timing, combinations, and activated forms ... 00:23:13 Dose: fairy dusting, blends, and megadosing dangers ... 00:25:15 Checklist summary for supplement decisions ... 00:31:25 Conclusion and disclaimer ... 00:33:03 Our Amazing Sponsors: Vita Zero-Age Exosomes by Vitali Skincare ? a regenerative ?stacking? formula with exosomes, GHK-Cu, niacinamide, and glutathione designed to support your skin at a cellular level rather than just the surface; go to www.vitaliskincare.com/?ref=Nat20 and use code NAT20 for 20% off. Apollo Neuro ? A wearable nervous system support device that uses personalized SmartVibes technology to help you feel calmer, more focused, and better able to shift into rest mode without adding another complicated wellness routine. Head to apolloneuro.com/NATN Offer to receive 20% off.  Ultimate GI Repair by LVLUP Health ? a research-backed blend of peptides, zinc carnosine, and gut-support compounds designed to strengthen your gut lining, improve digestion, and support resilience from the inside out; head to lvluphealth.com and use code NAT for 20% off Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

Today, I?m joined by the insightful Siobhan Mitchell PhD, a leading expert on women?s health, mitochondria, and metabolic resilience. In our conversation, Siobhan reveals why so many women in their 30s and 40s feel like their metabolism is suddenly ?broken,? and unpacks the real science behind what?s happening beneath the surface?especially as our hormones begin to shift. Episode Timestamps: Introduction and host welcome ... 00:00:00 Introducing Speaker B and focus on women?s health ... 00:04:30 Growing interest in women?s health and clinical gaps ... 00:05:12 Body composition and metabolic changes in perimenopause ... 00:06:01 Hormonal shifts?not a broken metabolism ... 00:09:21 Addressing the root cause versus band-aids like GLP-1 ... 00:11:10 What?s happening beneath the surface in early perimenopause ... 00:12:40 Role of estrogen in appetite, glucose, and fat storage ... 00:13:12 Visceral fat, inflammation, and accelerated aging ... 00:15:02 Estrogen?s connection to mitochondrial function ... 00:16:15 Brain, muscle, and cognitive declines with estrogen loss ... 00:16:44 Environmental and mitochondrial factors in PCOS ... 00:21:09 Shift to belly fat and why fat storage changes ... 00:22:58 Mitochondria, immune system, and autoimmunity in women ... 00:29:16 Phytoestrogens, soy, and S-equol as hormone alternatives ... 00:32:37 S-equol?s benefits: metabolic, bone, and brain health ... 00:35:50 Soy fears, GMOs, and the purity of S-equol ... 00:46:25 Microbiome, Bifidobacterium breve, and estrogen recycling ... 00:49:18 GLP-1s versus supporting the root cause ... 00:53:01 Optimizing estrogen signaling for health span and menopause timing ... 00:55:20 When to use S-equol: timing and benefits ... 00:55:54 Reversing visceral fat and lifestyle factors ... 01:03:28 Our Amazing Sponsors: Manukora Honey - A simple upgrade to your daily routine, this Manuka honey delivers antioxidants, prebiotics, and naturally occurring MGO that you won?t get from regular sweeteners; head to http://manukora.com/natniddam to save up to 31% plus $25 in free gifts with the Starter Kit. Mitopure Gummies by Timeline - These clinically researched gummies support mitophagy to help renew your mitochondria and boost cellular energy, giving you a stronger biological foundation for resilience?visit http://timeline.com/nat20 to get 20% off. Daily Gut Detox by Just Thrive Health ? A gentle, science-backed detox powered by clinically proven immunoglobulins that bind and remove toxins while supporting your gut, immune system, and digestion?without harsh flushing or discomfort. Visit JustThriveHealth.com/NAT20 and use code NAT20 for 20% off your order, risk-free. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

Today, I?m joined by Andrea Donsky, a powerhouse nutritionist, menopause advocate, and author of the groundbreaking new book Nourishing Menopause. In our conversation, Andrea opens up about her deeply personal journey?how experiencing her first hot flash as a nutrition expert pushed her into years of curiosity, research, and ultimately, a mission to reimagine menopause as both a challenge and an opportunity. Episode Timestamps: Welcome, show intro, and purpose ... 00:00:00 Lack of menopause awareness and connecting symptoms ... 00:07:02 Mainstream vs. holistic menopause approaches ... 00:09:09 Surveying thousands of women and symptom discovery ... 00:11:16 Validating unusual menopause symptoms ... 00:13:41 Impact on relationships and the workplace ... 00:21:04 Early onset, variability, and importance of hormonal testing ... 00:25:32 Key takeaways: you?re not alone, support exists ... 00:28:16 Ovarian aging and overall health ... 00:29:47 Shifts in women?s health research ... 00:32:11 Designing impactful, diverse menopause surveys ... 00:33:41 Andrea?s ?Nourishing Menopause? book philosophy ... 00:35:12 Nourishment, longevity, and healthspan ... 00:37:23 Risks of muscling through menopause ... 00:39:52 Insulin resistance: causes, signs, and management ... 00:45:57 Meal timing, fasting, and metabolic flexibility ... 00:51:06 Personalized health testing and nutrition ... 00:56:0 Soy/phytoestrogen controversy ... 00:58:08 BALANCE blueprint and nutrition pillars ... 01:01:18 Managing stress, nervous system, and reframing menopause ... 01:05:31 Andrea?s non-negotiables and top practical tips ... 01:09:11 Our Amazing Sponsors: LongeFera by Regenerive - Most cheap Ashwagandha is bulked up with stems and leaves to inflate the ?actives.? Those parts can bring compounds you don?t actually want in your body. LongeFera ? fixes that with a root-only extract containing four newly identified bioactives, the ASHX4 Complex. Visit regenerive.co and use code NAT25 for 25% off. Micro-BOOST (Humic Mineral Complex) by BEAM Minerals - A concentrated liquid humic formula that binds and removes toxins like heavy metals, mold, and pollutants?working fast with just a daily shot. Head to http://www.beamminerals.com/NAT20, use code NAT20, and get 20% off your first order. CP1 Pure Collagen Peptides by Puori ? a clean, unflavored collagen that supports connective tissue, joints, and skin elasticity with a unique amino acid profile your body actually uses, plus Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

Today, I?m joined by the incredible Dr. Amie Hornaman, a leading thyroid expert and author of the brand new book, The Thyroid Fix. In our conversation, Dr. Hornaman opens up about her personal struggle with undiagnosed thyroid disease?a journey marked by frustrating medical gaslighting and the dismissive ?you?re normal? diagnoses from doctor after doctor. She reveals how that experience led her to become a passionate advocate for women (and men) suffering from thyroid dysfunction and a pioneer in holistic, root-cause approaches to healing. Episode Timestamps: Introduction and show purpose ... 00:00:00 Dr. Hornaman?s personal story and medical gaslighting ... 00:05:05 Journey to functional medicine and importance of symptom-based care ... 00:11:00 Recognizing key thyroid-related symptoms ... 00:14:51 Wearables and tracking thyroid-related trends ... 00:17:18 Understanding thyropause and hormone fluctuations after 40 ... 00:19:31 Impact of thyroid function on overall longevity and health ... 00:23:43 T4-only medication debate and need for personalized treatment ... 00:36:19 Why T4-only persists in conventional practice ... 00:40:40 T2, metabolism, mitochondrial health, and iodine ... 00:45:21 GLP-1 medications, thyroid optimization, and weight loss stories ... 00:50:16 Personalization of thyroid numbers and treatment ... 00:53:46 Functional versus conventional thyroid lab ranges ... 00:54:59 Thyroid?s connection to mood and mental health ... 00:56:42 When lifestyle alone can?t restore thyroid health ... 00:58:39 Biggest myth: TSH and T4-only standard of care ... 01:07:59 Our Amazing Sponsors: O?RACLE by Wizard Sciences ? A daily ozonated oil capsule designed to support immune balance, cellular communication, and antioxidant production without clinics, machines, or complicated routines; learn more at wizardsciences.com and use code NAT15 for 15% off. Quantum Upgrade - Supports nervous system balance without wearables or apps?just effortless, 24/7 quantum energy streaming. With 21+ studies showing measurable improvements in stress and cellular function, it?s easy to try for yourself. Visit quantumupgrade.io/NAT and use code NAT15 to start the free 15 day trial. MassZymes by BiOptimizers ? A full-spectrum digestive enzyme formula with 4x more protease to help break down protein into usable amino acids so your body actually benefits from what you eat?try it risk-free with a 365-day money-back guarantee and save 15% at bioptimizers.com/bionat with code BIONAT. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

Today, I?m thrilled to welcome Dr. Nasha Winters back to the show for part two of our powerful conversation. As a trailblazer in integrative oncology and a passionate advocate for the ?metabolic terrain? approach to health, Dr. Winters brings both deep expertise and a truly holistic perspective to the complex world of cancer and longevity. In this episode, she doesn?t just share concepts?she takes us into the heart of what it means to test, assess, and address our own health in real life, especially when we?re facing major diagnoses and difficult decisions. Episode Timestamps: Welcome & Introduction to Longevity Podcast ... 00:00:00 Metabolic Terrain Concept & Mitochondrial Health ... 00:05:00 The Test, Assess, Address Framework ... 00:08:08 Readiness, Honest Audit, and Lifestyle Evaluation ... 00:08:43 The Ten Terrain Drops in Cancer & Health ... 00:14:09 Emotional Foundations for Healing ... 00:15:01 Essential Lab Markers and the ?Trifecta? ... 00:16:52 Affordable, Early Detection Labs?CBC, CRP, LDH, ESR ... 00:17:32 Shift Work, Circadian Health, and Mitigating Strategies ... 00:29:11 Handling Overwhelm: Prioritizing Fundamentals ... 00:37:45 Prevention Myths: Sun, Meat, and Food Access ... 00:42:26 Home-Cooked Food & Community?s Healing Power ... 00:51:16 Behaviors That Seem Healthy But Aren?t (e.g., Excess Cardio) ... 00:54:55 Age-Specific Advice and Building Longevity ... 00:56:25 Cancer, Metabolic Flexibility, and Biomarker ?Under Five? Rule ... 01:02:32 Integrative Oncology?s Strengths & Misconceptions ... 01:08:48 Risks of Extreme Alternative or Mainstream Approaches ... 01:12:58 Post-2020: Changing Health Trends & Immune Patterns ... 01:17:03 Hope for the Future & Patient Empowerment ... 01:24:02 Our Amazing Sponsors: STEMREGEN by Stemregen - A daily formula designed to support your body?s natural repair systems by helping release your own stem cells into circulation, supporting recovery, resilience, and whole-body renewal at the source. Visit stemregen.co/NAT15 and use code NAT15. https://stemregen.co/NAT15 Vampire Exosome by Young Goose - A next-generation serum packed with three trillion PRP-derived exosomes and RejuvNAD to support collagen production and skin renewal at the cellular level?helping results build over time instead of fading fast. Shop HERE and use code NAT10. Bioregulators by Nature?s Marvels - targeted peptides designed to support cellular signaling and renewal across key systems like circadian rhythm, immune function, and vascular health as part of a foundational longevity stack; head to profound-health.com and use code NAT15 for 15% off your first order. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

Today, I'm joined by R Blank, a leading expert on electromagnetic fields (EMFs) and the founder of Shield Your Body. R Blank's journey began alongside his father, Dr. Martin Blank, a pioneering scientist who sounded the alarm about EMF exposure decades before most of us even considered it (The BioInitiative Report) a health concern. Together, they co-authored the groundbreaking book "Overpowered," and now R Blank is back with a new treasure trove of actionable advice in "Empowered." GET YOUR FREE CHAPTER OF THE BOOK HERE! Global Research - The BioInitiative Report If you decide you want to try any of the EMF safety devices you hear about today you can go to shieldyourbody.com and use code NAT for 20% off of your first purchase of shield your body products. Episode Timestamps: Introduction to Longevity Podcast and host credentials ... 00:00:00 Writing "Overpowered" and founding Shield Your Body ... 00:06:01 Motivation for creating solutions to EMF exposure ... 00:07:09 Non-native EMFs explained for longevity enthusiasts ... 00:15:22 Historical timeline of technological EMF exposure ... 00:18:46 Cellular mechanisms: DNA strand breaks and health risks ... 00:21:15 Voltage-gated calcium channels, oxidative stress, and health ... 00:25:52 Impact of EMFs on mitochondrial function and aging ... 00:25:32 How EMFs disrupt sleep and melatonin production ... 00:38:03 Behavioral changes to significantly reduce EMF exposure ... 00:43:43 Debunking ineffective EMF protection products ... 00:53:04 How to evaluate legitimate EMF shielding technology ... 00:54:05 Therapeutic EMF: Understanding PEMF vs harmful exposure ... 01:04:43 Three impactful strategies for EMF risk reduction ... 01:07:51 Policy gaps and wish-list EMF regulations ... 01:10:52 The cost and conviction of EMF advocacy ... 01:12:02 Advice for skeptics: The Bioinitiative Report ... 01:15:20 Where to access R Blank's book and resources ... 01:19:44 Our Amazing Sponsors: Qualia Creatine+ by Qualia Life ? A clinically formulated blend of two highly bioavailable forms of creatine plus magnesium and electrolytes to support lean muscle, cellular energy, and brain health?especially for women over 40 who naturally produce less with age. Go to qualialife.com/nathalie and use code NATHALIE to save up to 50%, plus an additional 15% off. MassZymes by BiOptimizers ? A full-spectrum digestive enzyme formula with 4x more protease to help break down protein into usable amino acids so your body actually benefits from what you eat?try it risk-free with a 365-day money-back guarantee and save 15% at bioptimizers.com/bionat with code BIONAT. Vita Zero-Age Exosomes by Vitali Skincare ? a regenerative ?stacking? formula with exosomes, GHK-Cu, niacinamide, and glutathione designed to support your skin at a cellular level rather than just the surface; go to www.vitaliskincare.com/?ref=Nat20 and use code NAT20 for 20% off. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

Today, I?m joined by the one and only Dr. Sandra Kaufmann?a true pioneer in the field of personalized longevity medicine and the creative force behind the Kaufman Protocol. In this episode, Sandra shares how a personal curiosity about why we age at the cellular level ultimately drew her away from a successful anesthesia career and into the world of building longevity strategies for real people. She opens up about the moment longevity became more than just an intellectual pursuit, and the surprising ways her work has grown into a global movement. Previous episodes: Episode #203: Everything You Need to Know About The Theory of Aging with Dr. Sandra Kaufmann Episode #55: Dr. Sandy Kaufmann Longevity Expert ? Sneak Peak at 3 New AntiAging Compounds That Have Earned a Spot in Her New Book Episode Timestamps: Welcome, podcast intro and longevity focus ... 00:00:00 The importance of truly individual longevity interventions ... 00:09:00 Problems with cholesterol oversimplification and statins ... 00:11:09 Fuel utilization changes with age and hormone shifts ... 00:14:38 Introduction to the Kaufman Protocol?s framework ... 00:17:39 Pitfalls of copying others? supplement stacks and extreme trends ... 00:21:21 Iron overload and personalized assessment strategies ... 00:24:46 Lab testing, history, and personalized follow-up ... 00:38:04 Deep dive: mast cells, inflammation, and aging ... 00:39:15 Mast cell stabilization options and estrogen?s influence ... 00:44:49 Defining ?superagers? and their core habits ... 00:58:34 Big misconceptions in anti-aging medicine (rapamycin, etc.) ... 01:05:52 Peptides, exosomes, and where advanced tools fit in a pyramid ... 01:07:31 Emerging testing, refined supplements, and the future ... 01:11:59 Three key questions to assess your personal aging priorities ... 01:18:24 Our Amazing Sponsors: Tro Zzz by Troscriptions ? A fast-acting sleep troche that dissolves in your cheek and combines melatonin with compounds like honokiol, adenosine, cordycepin, CBD, CBN, and 5-HTP to support deep, restorative sleep when travel, stress, or late workouts throw things off. Head to troscriptions.com and use code NAT10 for 10% off your first order. Ultimate GI Repair by LVLUP Health ? a research-backed blend of peptides, zinc carnosine, and gut-support compounds designed to strengthen your gut lining, improve digestion, and support resilience from the inside out; head to lvluphealth.com and use code NAT for 20% off Mitopure Gummies by Timeline - These clinically researched gummies support mitophagy to help renew your mitochondria and boost cellular energy, giving you a stronger biological foundation for resilience?visit timeline.com/NAT20 to get 20% off. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

Today, I?m joined by Todd Shipman, a curious mind who initially set out to debunk the world of quantum energy?and ended up completely rethinking how our biology, energy, and even our sense of connection really work. In this episode, Todd Shipman shares his surprising journey, from skeptic to quantum advocate, and walks us through what the quantum field is?using clear analogies that finally make sense of a subject that usually feels way too abstract. Visit quantumupgrade.io/NAT and use code NAT15 to start the free 15 day trial. Episode Timestamps: Introduction to the Longevity Podcast and host ... 00:00:00 Defining quantum energy on the subatomic level ... 00:05:39 What coherence means for health and energy ... 00:06:35 Wave and lake analogies for coherence/disruption ... 00:07:19 Modern EMFs, energetic chaos, and body responses ... 00:09:41 The quantum field as explained by Joe Dispenza ... 00:11:42 Becoming aware of the quantum field?s presence ... 00:12:14 Personal experiments and shifting beliefs ... 00:13:12 Blood test with a quantum necklace ... 00:15:05 Relating quantum energy to sunlight and frequencies ... 00:17:46 Quantum tech, proprietary methods, and skepticism ... 00:18:46 Nobel Prize, entanglement, and scientific validation ... 00:21:24 Twins, connection, and quantum entanglement ... 00:22:27 Mother-child energetic connection ... 00:25:20 Summary of Nobel-winning quantum entanglement study ... 00:27:14 Quantum info transfer and "no distance" ... 00:29:04 Why quantum energy matters for health ... 00:30:45 Research findings: ATP and wound healing via quantum entanglement ... 00:32:06 Clarifying the mechanism: reducing energetic stress ... 00:36:16 Our Amazing Sponsors: Bioregulators by Nature?s Marvels - targeted peptides designed to support cellular signaling and renewal across key systems like circadian rhythm, immune function, and vascular health as part of a foundational longevity stack; head to www.profound-health.com/?Aff=Longevity15  and use code NAT15 for 15% off your first order. Tro Zzz by Troscriptions ? A fast-acting sleep troche that dissolves in your cheek and combines melatonin with compounds like honokiol, adenosine, cordycepin, CBD, CBN, and 5-HTP to support deep, restorative sleep when travel, stress, or late workouts throw things off. Head to troscriptions.com and use code NAT10 for 10% off your first order. Vampire Exosome by Young Goose - A next-generation serum packed with three trillion PRP-derived exosomes and RejuvNAD to support collagen production and skin renewal at the cellular level?helping results build over time instead of fading fast. Shop at younggoose.com and use code NAT10. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

Today, I?m joined by the insightful Cynthia Thurlow, a leading voice in women?s health and the acclaimed author of The Menopause Gut. In this episode, Cynthia Thurlow gets real about the chaos of perimenopause?a time when so many women look in the mirror and ask, ?Who is this?? She opens up about why this transition, often dismissed or misunderstood, is actually a powerful wake-up call and a pivotal moment to reclaim our well-being. Cynthia Thurlow?s NEW book: The Menopause Gut Episode Timestamps: Podcast introduction and longevity themes ... 00:00:00 Cost of unaddressed perimenopause for women and communities ... 00:05:10 Hormonal chaos and clarity: How midlife prompts self-reinvention ... 00:06:11 Medical care gaps and the need for better menopause support ... 00:09:00 Estrogen decline, immune changes, and inflammation ... 00:17:25 Gut health, leaky gut, and links to autoimmunity in midlife ... 00:19:33 The gut-brain connection: Leaky gut and cognitive changes ... 00:25:05 Why "do less" resonates for high-achieving women in perimenopause ... 00:27:42 The role and controversy of GLP-1 medications ... 00:33:15 Gut microbiome, the estrobolome, and estrogen detoxification ... 00:44:21 Bacterial translocation and systemic impact of gut issues ... 00:49:34 Estrogen?s role in maintaining gut microbial diversity ... 00:53:31 The gut-ovarian axis, stress, trauma, and early menopause ... 01:00:06 The profound impact of stress on gut and hormones ... 01:08:31 Reframing menopause as opportunity and thriving post-transition ... 01:09:06 Our Amazing Sponsors: Sunlighten Sauna - Looking to support your recovery and calm your nervous system? Sunlighten offers full spectrum infrared saunas?compact enough for real homes, powerful enough to support detoxification, mitochondrial energy, and a smarter longevity routine. Visit https://get.sunlighten.com/natpodcast and use code natlongevity to save up to $1,600 plus get free shipping on your sauna purchase. MassZymes by BiOptimizers ? A full-spectrum digestive enzyme formula with 4x more protease to help break down protein into usable amino acids so your body actually benefits from what you eat?try it risk-free with a 365-day money-back guarantee and save 15% at bioptimizers.com/bionat with code BIONAT. O?RACLE by Wizard Sciences ? A daily ozonated oil capsule designed to support immune balance, cellular communication, and antioxidant production without clinics, machines, or complicated routines; learn more at wizardsciences.com and use code NAT15 for 15% off. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

Today, I?m joined by the insightful Caroline Alan, author of The Mineral Reset and co-founder of Beam Minerals. Caroline Alan shares her powerful story?a decade-long journey from chronic fatigue, brain fog, adrenal burnout, and persistent health challenges to discovering the true foundation of her recovery: replenishing trace minerals. After years of searching for answers and seeing countless specialists, it wasn?t another diet or protocol that brought her back to health, but addressing a deep, often-overlooked mineral deficiency. New Book: https://www.mineralresetbook.com/pre-order BEAM MINERALS: Head to http://www.beamminerals.com/NAT20, use code NAT20, and get 20% off your first order. Previous Episodes: Episode #138: Power of Minerals?Using Minerals to Increase Energy Levels and Detoxify from Heavy Metals Episode Timestamps: Introduction and host welcome ... 00:00:00 Why minerals are overlooked in conventional care ... 00:06:16 Oral and adrenal improvements with minerals ... 00:09:25 Gradual symptom resolution ... 00:12:17 Cellular health foundation ... 00:17:02 Modern mineral crisis and agriculture ... 00:24:53 Natural mineral ratios and bioavailability ... 00:32:57 Body as an ecosystem ... 00:33:46 Nervous system, stress, and minerals ... 00:41:27 Symptoms of deficiency ... 00:49:28 Testing mineral status ... 00:52:52 Why most supplements don?t work ... 00:55:54 Humic and fulvic for mineral delivery and detox ... 01:01:03 Practical mineral use and dosing ... 01:22:14 Minerals with sauna and red light ... 01:26:00 Our Amazing Sponsors: Qualia Creatine+ by Qualia Life ? A clinically formulated blend of two highly bioavailable forms of creatine plus magnesium and electrolytes to support lean muscle, cellular energy, and brain health?especially for women over 40 who naturally produce less with age. Go to qualialife.com/nathalie and use code NATHALIE to save up to 50%, plus an additional 15% off. Vita Zero-Age Exosomes by Vitali Skincare ? a regenerative ?stacking? formula with exosomes, GHK-Cu, niacinamide, and glutathione designed to support your skin at a cellular level rather than just the surface; go to www.vitaliskincare.com/?ref=Nat20 and use code NAT20 for 20% off. Ultimate GI Repair by LVLUP Health ? a research-backed blend of peptides, zinc carnosine, and gut-support compounds designed to strengthen your gut lining, improve digestion, and support resilience from the inside out; head to lvluphealth.com and use code NAT for 20% off. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

Today, I?m pulling together some of the most impactful conversations from the last three months on the Podcast. From breaking down the pitfalls of trendy weight loss drugs to uncovering silent heart health risks, and exploring how mitochondrial transplants and trauma healing are rewriting the story of resilience, these moments have truly shifted my perspective on what it means to pursue lasting wellness. Here are the full episodes: #401: Personalization Is EVERYTHING: The New Science of Weight Health, GLP-1s, and Building Lasting Longevity With Ashley Koff #414: Drop Dead Healthy? Why "Fit" Women & Men Still Have Fatal Heart Attacks! l Dr. Regina Druz #419: Origin Of Disease Is Hiding In Your Cells! Doctor Reveals How To Fix It Now l Dr. Natalie Yivgi-Ohana #421: Why You Can't Hack Longevity Until You Heal Hidden Stored Trauma! l Dr. Aimie Apigian #417: Feeling Depressed? Watch This First (It Might Not Be What You Think) l Dr. Cynthia Keller l Ep  Episode Timestamps: Welcome and quarterly recap intro ... 00:00:00 Longevity is about pattern recognition, not single breakthroughs ... 00:00:41 GLP-1s require personalization, not a one-size-fits-all approach ... 00:04:25 GLP-1 hormone assessment and individualized plans ... 00:06:03 Delayed/suppressed GLP-1 function needs lifestyle changes ... 00:08:04 GLP-1 agonists enable, but don?t replace, foundational health tweaks ... 00:09:06 Heart health: sick fat disease, inflammation and cardiac risk ... 00:12:30 GLP-1 and GIP peptides have powerful anti-inflammatory effects ... 00:15:35 Menopause amplifies pre-existing heart/metabolic risks ... 00:18:22 Mitochondrial transplants: emerging therapy for rare diseases ... 00:24:04 Every disease linked to?or helped by?mitochondrial function ... 00:27:00 Trauma healing is phased; start with the gentle approach ... 00:31:21 Chronic survival state rewires the nervous system ... 00:40:02 Covid?s gut impact can trigger mood issues, fixed with key nutrients ... 00:50:00 Our Amazing Sponsors: Mitopure Gummies by Timeline - These clinically researched gummies support mitophagy to help renew your mitochondria and boost cellular energy, giving you a stronger biological foundation for resilience?visit timeline.com/nat20 to get 20% off. Quantum Upgrade - Supports nervous system balance without wearables or apps?just effortless, 24/7 quantum energy streaming. With 21+ studies showing measurable improvements in stress and cellular function, it?s easy to try for yourself. Visit quantumupgrade.io/NAT and use code NAT15 to start the free 15 day trial. Daily Gut Detox by Just Thrive Health ? A gentle, science-backed detox powered by clinically proven immunoglobulins that bind and remove toxins while supporting your gut, immune system, and digestion?without harsh flushing or discomfort. Visit JustThriveHealth.com/NAT20 and use code NAT20 for 20% off your order, risk-free. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

Today, I?m joined by the remarkable Dr. Nasha Winters, whose personal journey of facing stage four cancer at just 19 years old turned into a decades-long mission to rethink the narrative around cancer, healing, and human potential. In our conversation, Dr. Winters opens up about those early days?what it felt like to receive a grim prognosis, the mindset shift that changed her path, and how questioning medical certainties led her to new paradigms in both conventional and integrative oncology. Episode Timestamps: Welcome & Host Introduction ... 00:00:00 Dr. Nasha Winters? Cancer Diagnosis ... 00:00:54 Accidental Therapeutic Fasting and Healing ... 00:13:00 Questioning Medical Certainty & Turning to Alternatives ... 00:11:26 Journey Underground: Medical Rejection & Self-Discovery ... 00:14:02 Personalized Medicine, Mindset, and Radical Remission ... 00:19:22 Integrating Conventional and Alternative Approaches ... 00:22:04 The Science and Controversies of Fasting for Cancer ... 00:24:51 Cancer as Information Rather Than an Enemy ... 00:25:46 The Shift to Terrain Theory ... 00:34:22 Impact of Trauma, Mindset, and Nervous System on Healing ... 00:37:14 Lessons from Failed Treatments & Importance of Context ... 00:43:12 From Dietary Dogma to Metabolic Flexibility ... 01:00:54 Prevention, Hypervigilance, and the Power of Audit ... 01:10:02 Annual Longevity Testing and Sneaky Early Signs ... 01:23:16 Innovating Cancer & Longevity Research ... 01:33:37 Our Amazing Sponsors: STEMREGEN - A daily formula designed to support your body?s natural repair systems by helping release your own stem cells into circulation, supporting recovery, resilience, and whole-body renewal at the source. Visit stemregen.co/NAT15 and use code NAT15. Manukora Honey - A simple upgrade to your daily routine, this Manuka honey delivers antioxidants, prebiotics, and naturally occurring MGO that you won?t get from regular sweeteners; head to manukora.com/NAT to save up to 31% plus $25 in free gifts with the Starter Kit. Bioregulators by Nature?s Marvels - targeted peptides designed to support cellular signaling and renewal across key systems like circadian rhythm, immune function, and vascular health as part of a foundational longevity stack; head to profound-health.com and use code NAT15 for 15% off your first order. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

Today, I'm joined by Dr. Grace Liu, often known as the ?Gut Goddess,? a trailblazer in the world of microbiome science and founder of The Gut Institute. In this conversation, we take a bold dive into an often-overlooked pillar of longevity: your poop. That's right?Dr. Liu unpacks the fascinating and sometimes surprising science showing how gut health shapes everything from your immune system and brain to your lifespan itself. Episode Timestamps: Introduction to host ... 00:00:00 Dr. Grace Liu on the gut as a hallmark of aging ... 00:04:06 Peptides, FMT, and evidence for gut-driven regeneration ... 00:05:04 FMT safety, immune education, and the environmental ?microdosing? effect ... 00:07:07 Links between gut aging, the immune system, and mental health ... 00:08:13 Diet, ancestry, and resistant starch for butyrate production ... 00:15:01 Ancestral diet, microbiome differences, and pitfalls of shortcuts ... 00:18:53 Fiber, polyphenols, and the key longevity bacteria ... 00:24:09 Gut markers, loss of diversity, and ABC species signature ... 00:25:15 Risks of overhyped probiotics, strep, and broad interventions ... 00:36:29 Peptides, bioregulators, and repairing the gut ... 01:12:01 Practical longevity: movement, daily habits & where to learn more ... 01:22:46 Our Amazing Sponsors: Tro Zzz by Troscriptions ? A fast-acting sleep troche that dissolves in your cheek and combines melatonin with compounds like honokiol, adenosine, cordycepin, CBD, CBN, and 5-HTP to support deep, restorative sleep when travel, stress, or late workouts throw things off. Head to troscriptions.com and use code NAT10 for 10% off your first order.  O?RACLE by Wizard Sciences ? A daily ozonated oil capsule designed to support immune balance, cellular communication, and antioxidant production without clinics, machines, or complicated routines; learn more at wizardsciences.com and use code NAT15 for 15% off. CP1 Pure Collagen Peptides by Puori ? a clean, unflavored collagen that supports connective tissue, joints, and skin elasticity with a unique amino acid profile your body actually uses, plus full third-party testing; go to puori.com/NAT and use code NAT for 32% off when you start a subscription. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

Today, I'm joined by the insightful Dr. Meenal Agarwal, an eye doctor and passionate advocate for reimagining how we think about vision and brain health. In our conversation, Dr. Agarwal reveals the surprising ways our daily screen habits are shaping not just our eyesight, but also our emotional regulation, cognitive performance, and even the development of anxiety and ADHD-like symptoms. She opens up about her own journey?from an unexpected period of cognitive "off-ness" during a stint away from her clinical work, to pioneering a powerful perspective on "spatial awareness processing disorder."

 

Episode Timestamps:

Introduction and Episode Overview ... 00:00:00

Impact of Vision on Brain and Longevity ... 00:00:37

Sponsors: Gut and Toxin Health ... 00:01:07

Eye-Brain Connection Fundamentals ... 00:04:30

Peripheral Vision, Screens, and Anxiety ... 00:08:06

Case Study: Childhood Myopia and Screens ... 00:20:37

Prevention: Breaks and the 20-20-20 Rule ... 00:25:30

Recognizing and Addressing Spatial Processing Issues ... 00:27:25

Annual Eye Exams and Early Detection ... 01:09:40

Nutrition and Biohacks for Eye-Brain Health ... 01:17:13

Advice for Parents and Screen Balance ... 01:14:08

Book Insights and Closing ... 01:24:28

Where to Find Dr. Agarwal ... 01:26:45

 

Our Amazing Sponsors:

Ultimate GI Repair by LVLUP Health ? a research-backed blend of peptides, zinc carnosine, and gut-support compounds designed to strengthen your gut lining, improve digestion, and support resilience from the inside out; head to lvluphealth.com and use code NAT for 20% off

 

Micro-BOOST (Humic Mineral Complex) by BEAM Minerals - A concentrated liquid humic formula that binds and removes toxins like heavy metals, mold, and pollutants?working fast with just a daily shot. Head to http://www.beamminerals.com/NAT20, use code NAT20, and get 20% off your first order. 

 

Vita Zero-Age Exosomes by Vitali Skincare ? a regenerative "stacking" formula with exosomes, GHK-Cu, niacinamide, and glutathione designed to support your skin at a cellular level rather than just the surface; go to www.vitaliskincare.com/?ref=Nat20 and use code NAT20 for 20% off.

 

Nat's Links: 

YouTube Channel

Join My Membership Community

Sign up for My Newsletter 

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Dr. Bill Lawrence Episode

Today, I'm joined by the amazing Melissa Urban, the force behind Whole30 and a global champion of accessible nutrition. In our conversation, Melissa opens up about a surprising discovery in her wellness journey: sleep, not just food, is often the real foundation of long-term health. She shares how overlooked sleep hijacked her cravings, impacted her insulin sensitivity, and even chipped away at her resilience?revealing the invisible costs that only show up years down the line.

 

Visit ozlosleep.com/nat and use code NAT to get $95 off

 

Episode Timestamps:

Welcome and podcast introduction ... 00:00:00

Poor sleep's impact on cravings and insulin ... 00:00:47

Melissa Urban's wake-up calls: burnout and disrupted sleep ... 00:00:59

Tech sleep hack: Ozlo noise-canceling earbuds ... 00:01:06

Sleep's effect on diet and insulin sensitivity ... 00:06:42

Cravings, mood, and resilience with sleep loss ... 00:08:49

Melissa Urban's sleep disruption stories: motherhood, book tour, menopause ... 00:10:02

Sleep and technology: SleepBuds saving marriage ... 00:12:42

Sleep consistency as key for resilience and health ... 00:17:47

Chronic light sleep: cognitive and metabolic consequences ... 00:20:09

Hormonal disruption and menopause sleep challenges ... 00:24:42

Sleep refresh tips: environment and habits ... 00:26:07

Screen-free wind-down routines ... 00:27:41

Midlife sleep wisdom: earlier bedtime ... 00:34:37

Physical and mental benefits of good sleep ... 00:36:06

Noise canceling vs. masking: SleepBuds explained ... 00:39:18

Sleep supplements: magnesium, melatonin, CBD ... 00:48:28

One impactful habit: eliminate screens and alcohol ... 00:53:30

Where to find Melissa Urban and Ozlo ... 00:56:27

 

Our Amazing Sponsors:

Vampire Exosome by Young Goose - A next-generation serum packed with three trillion PRP-derived exosomes and RejuvNAD? to support collagen production and skin renewal at the cellular level?helping results build over time instead of fading fast. Shop at younggoose.com and use code NAT10

 

MassZymes by BiOptimizers ? A full-spectrum digestive enzyme formula with 4x more protease to help break down protein into usable amino acids so your body actually benefits from what you eat?try it risk-free with a 365-day money-back guarantee and save 15% at bioptimizers.com/bionat with code BIONAT.

 

Mitopure Gummies by Timeline - These clinically researched gummies support mitophagy to help renew your mitochondria and boost cellular energy, giving you a stronger biological foundation for resilience?visit timeline.com/NAT to get 20% off.

 

Nat's Links: 

YouTube Channel

Join My Membership Community

Sign up for My Newsletter 

Instagram 

Dr. Bill Lawrence Episode

Today, I'm joined by David Roberts and Dr. John Gildea, two passionate researchers whose work sits at the cutting edge of environmental health and longevity science. In this episode, we dive deep into the catalyst for developing a stabilized sulforaphane supplement?something born out of both necessity and relentless curiosity. David opens up about how environmental toxicity stopped being theoretical for him, and Dr. Gildea brings a wealth of clinical insight into why supporting our detox pathways could be a game-changer for chronic disease prevention.

Offer: Get 25% off stabilized sulforaphane products for a limited time at mara-labs.com/NAT with code NAT (offer ends April 7th 2026; 15% off thereafter).

 

Episode Timestamps:

Welcome and podcast intro ... 00:00:00

When toxins became personal: cancer & environment ... 00:04:54

Practical detox: household and lifestyle changes ... 00:06:12

Sulforaphane's effect on inflammation and daily function ...00:07:07

Finding health solutions outside conventional medicine ... 00:14:44

Cancer diagnosis prompts sulforaphane stabilization ... 00:18:17

NRF2: master regulator in aging, skin, and detox ... 00:24:16

Sulforaphane, curcumin, and inflammation ... 00:25:11

Supplement confusion: sulforaphane vs. glucoraphanin ... 00:31:10

Food as medicine and practical dosing ... 00:34:51

Microplastics: exposure, health risks, and impacts ... 00:35:31

Detox routes and microplastics research ... 00:47:04

Glyphosate, NRF2 suppression, and gut barriers ... 00:52:54

Sulforaphane boosts detox and protects against pollution ... 00:59:13

GLP-1s, muscle loss risk, and supplement alternatives ... 01:00:08

Berberine: sleep, glucose, and microbiome effects ... 01:06:12

Synergies, future research, and sulforaphane limits ... 01:10:32

Sprouts, seeds, and potency of broccoli compounds ... 01:16:17

 

Our Amazing Sponsors:

Vitali SkinCare - combines pharmaceutical-grade copper peptides with zero-age exosomes to support clearer cellular signaling and long-term skin resilience, working with your biology instead of forcing change. Visit VitaliSkincare.com and use code NAT20 for 20% off.

 

Tro Zzz by Troscriptions ? a fast-acting, customizable sleep formula designed to quiet racing thoughts and support deeper, more restorative sleep using a powerful blend of GABA-supporting compounds, cannabinoids, and sleep-promoting ingredients. Head to troscriptions.com, use code NAT10, and get 10% off.

 

Complete Liver Complex by LVLUP Health - supports your liver's natural detox pathways so your body can reset after the holidays without suffering. Go to lvluphealth.com and use code NAT for 20% off.

 

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Dr. Bill Lawrence Episode

Today, I'm joined by Erin Ryan, my producer, for a special follow-up episode where we tackle your most pressing questions about bioregulators and peptides. After the wildly popular Bill Lawrence interview, the Longevity Podcast community sent in a wave of thoughtful queries?from cancer concerns to menopause, sourcing, and practical tips.

Click Here for list of BIOREGULATOR NAMES

 

Books mentioned in this episode:

The Peptide Bioregulator Revolution (Great primer on bioregulators)

Author: Dr. Marios Kyriazis

Peptides and the Epigenetic Control of Aging  (Technical, science-heavy)

Author: PhD Vladimir Khavinson, MD, PharmaB Phil Micans, MS, PhD Alexander Maryanovich, MD 

 

Episode Timestamps:

Welcome and sponsor introduction ... 00:00:00

Autophagy and Primadene ... 00:00:44

Bioregulator basics and liver support ... 00:01:58

Cancer and telomere lengthening peptides ... 00:05:56

Bioregulators and cancer: caution advised ... 00:08:06

Immune bioregulators and cancer recovery ... 00:12:31

Book reference: "Peptide Bioregulator Revolution" ... 00:13:54

Bioregulators for immune support ... 00:14:44

When not to use bioregulators ... 00:16:56

Menopause, ovarian aging, and bioregulators ... 00:17:47

Clinical outcomes in women ... 00:23:57

GLP-1s and bioregulator absorption ... 00:27:01

Preventative strategies by age ... 00:28:57

Epitalon safety and dosing ... 00:33:18

Bioregulator sourcing and access ... 00:35:41

Amazon caution for supplements ... 00:38:01

Emerging science and trusted brands ... 00:40:03

Social media challenges and newsletter ... 00:44:30

 

Our Amazing Sponsors:

Primeadine by Oxford Healthspan ? A food-derived spermidine supplement that supports autophagy and cellular renewal without fasting, made from Japanese wheat germ with clean, rigorously tested ingredients (including a gluten-free option); visit oxfordhealthspan.com/BIONAT20 and use code BIONAT20 at checkout.

 

Nature's Marvels Bioregulators - provide gentle, organ-specific support ? and the Liver Bioregulator is a favorite this season for supporting detox pathways and metabolic flow. Head to profound-health.com and use code NAT15 for 15% off your first order.   http://www.profound-health.com/?Aff=Longevity15

 

O?RACLE by Wizard Sciences ? A daily ozonated oil capsule designed to support immune balance, cellular communication, and antioxidant production without clinics, machines, or complicated routines; learn more at wizardsciences.com and use code NAT15 for 15% off.

 

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Dr. Bill Lawrence Episode

Today, I'm joined by the insightful Dr. Nafysa Parpia, a true leader in environmental and complex chronic illness medicine and the Director of Naturopathic Medicine at Gordon Medical. In our conversation, Dr. Parpia shares how her passion for deep, integrated healing brought her into the world of environmental toxins, hormone health, and the nuanced ways our bodies respond to the modern world. She opens up about her journey, the unique challenges women face?especially during menopause?and why so many aren't finding answers in traditional medicine.

 

Episode Timestamps:

Welcome & episode goals ... 00:00:00

Environmental toxins and complex illness ... 00:01:17

Rise of chronic illnesses; environmental triggers ... 00:07:26

Lead, bone loss, and menopause ... 00:10:03

Sources of lead exposure today ... 00:12:03

Chelation therapy: what, when, and how ... 00:14:26

Opening detox pathways: herbs and bioregulators ... 00:17:17

Menopause, toxic burden, and immune shifts ... 00:20:49

CDC data: multiple toxins and cumulative risk ... 00:23:02

Genetics, nutrition, and susceptibility ... 00:28:12

Personalized medicine & system constraints ... 00:30:03

Heavy metals, inflammation, and hormone effects ... 00:35:35

Peptide and bioregulator therapy: sequencing matters ... 00:41:12

Testing mistakes: over- and under-testing ... 00:57:41

Preparing for detox: the Pretox approach ... 01:02:58

Sensitivity to binders and protocol adjustments ... 01:16:50

Plasmapheresis (TPE): science and application ... 01:19:19

Optimizing menopause care and women's self-sovereignty ...  01:25:28

 

Our Amazing Sponsors:

STEMREGEN - A plant-based formula designed to support your body's natural stem cell release, circulation, and repair processes so you can recover and regenerate more effectively. Visit www.stemregen.co/nat and use code NAT15 for your exclusive discount.

 

Magnesium Breakthrough by BIOptimizers ? A full-spectrum magnesium supplement combining seven highly absorbable forms to support sleep, stress, muscle recovery, and nervous system balance in one nightly habit. Save 15% at bioptimizers.com/bionat with code BIONAT

 

Youth Daily by Young Goose ? An all-in-one moisturizer powered by NAD+ nano precursors to boost elasticity, smooth wrinkles, and keep your skin looking fresh, dewy, and full of life; grab yours HERE and use code Nat10

 

 

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Dr. Bill Lawrence Episode

Today, I'm joined by the legendary Dr. Jeffrey Bland, widely known as the "father of functional medicine" and a true pioneer in the science of longevity and immune resilience. In this conversation, Dr. Jeffrey Bland opens up about his decades-long journey questioning the conventional medicine model, the personal moments that shaped his mission, and how his passion for asking the right questions ultimately led him to reshape the future of healthcare.

Visit Bigboldhealth.com/NAT and get 15% off automatically at checkout.

 

Episode Timestamps:

Focus on immune system aging ... 00:00:00

Questioning conventional medicine and the roots of chronic disease ... 00:05:00

Functional medicine and influences like Linus Pauling ... 00:12:39

Dangers of oversimplification and the limits of biohacking ... 00:17:21

Evolving thinking on supplements and the power of cycling and personalization ... 00:19:37

Why immune resilience trumps immune boosting for longevity ... 00:25:21

Diet's impact on immune cell turnover and long-term health ... 00:28:57

Autoimmunity, CHIP cells, inflammaging, and biological individuality ... 00:32:04

Microbiome, mitochondria, and immune-driven fatigue ... 01:00:07

The 4R gut and immune program as a starting point ... 01:06:26

Movement, lymphatics, and rejuvenation ... 01:08:35

Food as information, epigenetics, and practical recommendations ... 01:11:25

90-day immune system renewal and rapid-fire takeaways ... 01:31:40

 

Our Amazing Sponsors:

Quantum Upgrade - Supports nervous system balance without wearables or apps?just effortless, 24/7 quantum energy streaming. With 21+ studies showing measurable improvements in stress and cellular function, it's easy to try for yourself. Visit quantumupgrade.io/NAT and use code NAT15 to start the free 15 day trial.

 

Primeadine by Oxford Healthspan ? A food-derived spermidine supplement that supports autophagy and cellular renewal without fasting, made from Japanese wheat germ with clean, rigorously tested ingredients (including a gluten-free option); visit oxfordhealthspan.com/BIONAT20 and use code BIONAT20 at checkout.

 

PW1 by Puori ? A clean, high-quality whey protein that's third-party tested for over 200 contaminants and smooth enough to feel like a treat while supporting muscle, metabolism, and bone strength. Go to puori.com/NAT and use code NAT for 32% off your first subscription or 20% off anything on the site.

 

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Dr. Bill Lawrence Episode

Today, I'm joined by Dr. Aimie Apigian, an innovative leader in the biology of trauma, whose work bridges the worlds of science, medicine, and lived experience. In our conversation, Dr. Apigian opens up about her journey from conventional medicine?where symptom management was the norm?to uncovering the physiological roots of trauma and the crucial role our nervous system plays in resilience and healing. She shares how her own health struggles, her work with adopted children, and a relentless curiosity led her to re-examine everything she thought she knew about stress, autoimmunity, and capacity. The 7-Day Somatic Healing for Stored Emotions - https://traumahealingaccelerated.mykajabi.com/a/2148170319/wdrhGYaY 21-Day Journey, a daily live session program that helps participants understand how much trauma their body may be holding - https://traumahealingaccelerated.mykajabi.com/a/2147704575/wdrhGYaY Episode Timestamps: Introduction, host's mission, and episode theme ... 00:00:00 Science behind trauma, limits of traditional medicine, and autoimmune experiences ... 00:06:11 Attachment, symptom management, functional medicine, and healing journey ... 00:08:17 Mold exposure, state triggers, brain inflammation, and capacity blocks ... 00:14:22 Medical gaslighting, trauma validation, and biological capacity ... 00:18:25 Safety, resilience, and chronic survival state effects ... 00:19:32 Misconceptions about chronic stress?emergency brake and vagus nerve ... 00:22:27 Attachment patterns, autoimmunity, and shrinking world ... 00:28:47 Chronic survival loop, exhaustion, coping strategies, and shutdown ... 00:31:11 Moving to repair: phases of healing and gentle approaches ... 00:34:08 Somatic practices, art therapy, and different expressions of trauma ... 00:39:01 Shifts in sleep, digestion, anxiety, and felt safety ... 00:42:06 Tracking nervous system state: strategies and awareness ... 00:46:41 Therapy limitations: biology and somatic integration ... 00:48:42 Retraining vs. managing symptoms, stabilization, and healing ... 00:54:53 Capacity, resilience, lessons from centenarians, and longevity ... 01:00:06 Trauma's impact on mitochondria, telomeres, and generational health ... 01:06:27 Gut microbiome and trauma: two-way connection ... 01:08:03 Our Amazing Sponsors: Manukora Honey - rich, creamy Manuka honey packed with powerful bioactives, all in just one heaped teaspoon a day. Go to MANUKORA.com/NAT to save up to 31% plus $25 in free gifts with the Starter Kit. Mitopure Longevity Gummies by Timeline ? Clinically backed Urolithin A supports mitochondrial health to boost energy, recovery, and healthy aging, all in an easy daily gummy instead of another pill; go to timeline.com/nat20 for 20% off Mitopure Gummies. Ozlo - use smart sound engineering and sleep detection to help you stay in deeper, more stable sleep all night. Create your ideal sleep environment anywhere: go to ozlosleep.com/nat and use code NAT to get $75 off. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

Today, I'm joined by the inspiring Leslie Kenny, Oxford-based longevity expert and a living example of turning adversity into vitality. After being told at 39 that she had lupus, rheumatoid arthritis, and just five years to live, Leslie defiantly forged a new path?reversing her diagnoses, restoring her thyroid health, and even welcoming a healthy baby girl at 43. Her story is a testament to the power of questioning the status quo, honoring the wisdom within our bodies, and refusing to accept decline as inevitable. Leslie has a generous offer for you, when you visit oxfordhealthspan.com/BIONAT20 and use code BIONAT20 at checkout you'll get 20% off. Episode Timestamps: Welcome, show intro, and overview ... 00:00:00 Leslie Kenny's health journey and reversing disease ... 00:00:30 Biological vs. chronological age and the immune system ... 00:04:55 Impact of trauma and stress on aging ... 00:11:51 Overcoming prognosis: lifestyle and scientific interventions ... 00:18:02 Diet, tracking, and removing triggers ... 00:22:21 The overlooked importance of thyroid health ... 00:32:23 Dangers of overdoing fasting and hormesis ... 00:40:21 Autophagy basics and the cellular cleanup crew ... 00:44:06 Spermidine's role, sourcing, and supplement quality ... 01:10:19 Optimizing longevity habits and daily routines ... 01:29:44 Our Amazing Sponsors: Tro Zzz by Troscriptions ? A fast-acting sleep troche that dissolves in your cheek and combines melatonin with compounds like honokiol, adenosine, cordycepin, CBD, CBN, and 5-HTP to support deep, restorative sleep when travel, stress, or late workouts throw things off. Head to troscriptions.com and use code NAT10 for 10% off your first order. BEAM Minerals - Low energy often starts in the mitochondria. Support cellular energy with a bioavailable liquid mineral supplement ? and get 20% off at beamminerals.com with code NAT20. Nature's Marvels Bioregulators - provide gentle, organ-specific support ? and the Liver Bioregulator is a favorite this season for supporting detox pathways and metabolic flow. Head to http://www.profound-health.com/?Aff=Longevity15 and use code NAT15 for 15% off your first order. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

Today, I'm joined by the extraordinary Dr. Natalie Yivgi-Ohana, a pioneering scientist whose passion for mitochondria unlocks new frontiers in longevity medicine. Our conversation truly blew my mind?Dr. Yivgi-Ohana brings decades of expertise to demystify these tiny, ancient powerhouses that fuel every cell in our bodies, impact our hormones, drive immunity, and, as it turns out, play a central role in how we age. Episode Timestamps: Welcome to the Longevity Podcast and today's focus on mitochondria ... 00:00:00 Maternal inheritance and critical functions of mitochondria ... 00:05:56 Mitochondria as energy producers and hormone regulators ... 00:07:03 Aha moments: mitochondria control life, death, and disease ... 00:08:55 Endosymbiotic theory: how mitochondria originated ... 00:10:19 Chronic disease, aging, and the connection to mitochondria ... 00:16:10 Substrate fuels: carbs, fats, and importance of metabolic flexibility ... 00:20:18 Mitochondria's control over immune system and signaling ... 00:26:39 Mitochondrial transfer: how cells share organelle "powerhouses" ... 00:32:42 Groundbreaking therapy: transplanting mitochondria for rare diseases ... 00:36:40 Expanding mitochondrial therapies to age-related diseases ... 00:42:57 Aging in women: hormones, mitochondria, and inflection points ... 00:51:00 Stem cell exhaustion and cellular renewal ... 00:52:24 Biomarkers: ways to measure mitochondrial health ... 01:03:11 Supplements, lifestyle, and emotional health for mitochondria ... 01:15:47 Medication choices and minimizing mitochondrial toxicity ... 01:24:04 Our Amazing Sponsors: O?RACLE by Wizard Sciences ? A daily ozonated oil capsule designed to support immune balance, cellular communication, and antioxidant production without clinics, machines, or complicated routines; learn more at wizardsciences.com and use code NAT15 for 15% off. Magnesium Breakthrough by BIOptimizers ? A full-spectrum magnesium supplement combining seven highly absorbable forms to support sleep, stress, muscle recovery, and nervous system balance in one nightly habit. Save 15% at bioptimizers.com/bionat with code BIONAT Vitali - combines pharmaceutical-grade copper peptides with zero-age exosomes to support clearer cellular signaling and long-term skin resilience, working with your biology instead of forcing change. Visit VitaliSkincare.com and use code NAT20 for 20% off. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

Today, I'm joined by the insightful Courtney Van Bussum, a biomedical engineer and entrepreneur who has become a rising force in longevity science. Courtney shares how growing up in a family of healthcare innovators shaped her journey, and how she pivoted from startup life to tackling age-related challenges?especially when COVID brought her back to her roots and reignited her passion for cellular health. If you want to try Endotelio 1-MNA and save 10% click here and code NAT10 will be entered for you at checkout. Episode Timestamps: Welcome and introduction to Longevity Podcast ... 00:00:00 Challenging beliefs about aging and cellular health ... 00:12:00 Deep dive into NAD+ biochemistry and cellular function ... 00:13:08 NAD+/NADH balance: Why both matter ... 00:15:24 Why NAD+ declines: Not just aging, but increased degradation ...00:18:26 The role of CD38 and NMNT enzymes in NAD metabolism ... 00:20:14 Controversy and confusion: NAD+ precursors (NR, NMN) and IVs ... 00:22:28 Methylation's hidden importance in NAD supplementation ... 00:30:55 Supplementing 1-MNA: Understanding dosages and applications ... 00:50:54 Assessing NAD+ status: Biomarkers and limitations of testing ... 00:53:01 Lifestyle ROI: Sleep, exercise, and circadian rhythm for NAD preservation ... 00:57:14 Ketones: Beyond performance, supporting cellular energy and longevity ... 01:06:03 Future of NAD science: Anticipating new insights and risks ... 01:11:45 Confidence and humility: Advice for navigating the longevity field ... 01:18:52 Our Amazing Sponsors: Qualia Creatine+ by Qualia Life ? A clinically formulated blend of two highly bioavailable forms of creatine plus magnesium and electrolytes to support lean muscle, cellular energy, and brain health?especially for women over 40 who naturally produce less with age. Go to qualialife.com/nathalie and use code NATHALIE to save up to 50%, plus an additional 15% off. Complete Liver Complex by LVLUP Health - supports your liver's natural detox pathways so your body can reset after the holidays without suffering. Go to lvluphealth.com and use code NAT for 20% off. Gut Essentials Bundle by Just Thrive Health ? This powerhouse duo pairs the only probiotic clinically proven to arrive 100% alive in your gut with science-backed Digestive Bitters to reduce bloat, curb cravings, and support better energy fast. Take the Just Thrive Feel Better Challenge and save 20% at justthrivehealth.com/NAT20 with code NAT20. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

Today, I'm joined by the innovative Dr. Cynthia Keller, a pediatrician whose passion for integrative and functional medicine has reshaped how we understand post-COVID health challenges. Dr. Keller opens up about her journey from conventional medicine to designing unique solutions for children and families, revealing how her care, presence, and determination to "solve the unsolvable" led to breakthroughs in treating mood changes, weight gain, and energy loss after COVID. Special Offer: If you go to alchemicmedicinals.com and use code NatRocks at checkout, you'll get a whopping 50% off of the Tryptophan Re-Genesis? Powder while supplies last! (Capsules not included). Episode Timestamps: Introduction and host's mission ... 00:00:00 From standard care to integrative pediatrics ... 00:05:05 Patterns in pediatric development and disease ... 00:09:19 Gut health, emotional factors, and parenting ... 00:10:44 Clinic model and multidisciplinary care ... 00:15:04 Post-COVID nutrient depletion: clinical discoveries ... 00:18:03 Key depleted cofactors and rapid recovery ... 00:19:31 COVID's ongoing impact on gut and microbiome ... 00:24:39 Grassroots collaboration and evolving strategies ... 00:26:28 Clinical patterns: mood, weight, thirst ... 00:36:02 Family-wide interventions and quick results ... 00:46:24 Symptoms-based approach, minimal testing ... 00:52:07 Supplementation protocol and cautions ... 00:57:14 Product development and access ... 01:08:22 Infant microbiome and generational shifts ... 01:10:28 Pediatricians: importance of listening and presence ... 01:20:09 Love and connection in clinical care ... 01:21:01 Modern dysregulation: loss of boredom ... 01:22:28 Our Amazing Sponsors: Ozlo - use smart sound engineering and sleep detection to help you stay in deeper, more stable sleep all night. Create your ideal sleep environment anywhere: go to ozlosleep.com/nat and use code NAT to get $75 off. Youth Daily by Young Goose ? An all-in-one moisturizer powered by NAD+ nano precursors to boost elasticity, smooth wrinkles, and keep your skin looking fresh, dewy, and full of life; grab yours at younggoose.com and use code Nat10 for first orders or this link and code 5NAT for returning customers. Mitopure Longevity Gummies by Timeline ? Clinically backed Urolithin A supports mitochondrial health to boost energy, recovery, and healthy aging, all in an easy daily gummy instead of another pill; go to timeline.com/nat20 for 20% off Mitopure Gummies. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

Today, I'm joined by the remarkable Cathy Eason, whose work in the nitric oxide and vascular health space is changing the conversation around resilience and heart health for midlife women. Cathy dives into why cardiovascular disease is still the number one threat to women globally, and how the drop in estrogen during menopause impacts nitric oxide production?an overlooked factor that quietly influences everything from energy to cognition. Visit https://berkeleylife.pxf.io/NIDDBL and use code NAT20 for 20% off. Episode Timestamps: Podcast welcome and cardiovascular focus ... 00:00:00 Introducing Cathy Eason, nitric oxide updates ... 00:03:26 Menopause as a vascular event ... 00:08:50 Everyday signs of cardiovascular decline ... 00:11:19 Body awareness and tracking health metrics ... 00:14:15 Healthy labs but low resilience ... 00:16:56 Defining and understanding menopause ... 00:22:48 Systems affected during menopause ... 00:25:26 Nitric oxide's critical role ... 00:44:24 Testing and optimizing blood flow ... 00:48:14 Value of health patterns over labs ... 00:55:09 Communicating health trends to providers ... 00:56:32 Berkeley Life supplement recommendation ... 00:59:02 Prioritizing basic health habits ... 01:01:58 Longevity reframe: thriving with age ... 01:06:46 Advice for early action ... 01:07:09 Our Amazing Sponsors: Primeadine by Oxford Healthspan ? A food-derived spermidine supplement that supports autophagy and cellular renewal without fasting, made from Japanese wheat germ with clean, rigorously tested ingredients (including a gluten-free option); visit oxfordhealthspan.com/BIONAT20 and use code BIONAT20 at checkout. Magnesium Breakthrough by BIOptimizers ? A full-spectrum magnesium supplement combining seven highly absorbable forms to support sleep, stress, muscle recovery, and nervous system balance in one nightly habit. Save 15% at bioptimizers.com/bionat with code BIONAT Nature's Marvels Bioregulators - provide gentle, organ-specific support ? and the Liver Bioregulator is a favorite this season for supporting detox pathways and metabolic flow. Head to profound-health.com and use code NAT15 for 15% off your first order. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode