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(0:00) Bestie intros
(0:12) OpenAI declares "Code Red" as competitors eat away ChatGPT market share
(28:14) David Sacks vs. New York Times
(51:24) New poverty line, America's slow descent into socialism
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Referenced in the show:
Sacks's AI waiver:
https://www.whitehouse.gov/wp-content/uploads/2025/06/David-Sacks.pdf
Sacks's Crypto waiver:
https://www.whitehouse.gov/wp-content/uploads/2025/03/Memo-David-Sacks-3.5.2025-1.pdf
https://www.nytimes.com/2025/11/30/technology/david-sacks-white-house-profits.html
https://www.nytimes.com/2021/07/23/us/politics/anita-dunn-biden-white-house.html
(0:00) Molly Bloom joins the besties live in Las Vegas!
(1:48) Did Jason actually play in "Molly's Game"?
(3:23) Molly's background, starting the game, getting strong-armed by a famous actor, getting stiffed for $250K and losing the game
(16:54) Moving the game to NYC, mob involvement, legal troubles, writing her memoir and making the movie
(31:10) Best celebrity poker players, high-stakes poker archetypes, and more
(34:31) Sales coaching advice
Thanks to Oracle! Join Oracle AI Experience to discover how Oracle is your partner for accelerating your AI journey.
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(0:00) Bestie intros LIVE from The Venetian Las Vegas
(1:13) Epstein Files breakdown
(10:06) Biggest Epstein questions: where did his money come from?
(14:44) Tether's booming business
(23:50) Michael Burry vs. Friedberg, Nvidia's blowout quarter and risks for 2026
(35:25) Google's Gemini 3 and TPU breakthrough
(42:51) Investing your own money vs. LP capital, why Friedberg returned as a CEO
(48:57) Alan Keating joins the show to talk poker strategy, thriving in chaos, risk psychology
Special thanks to The Venetian Las Vegas for hosting us!:
Join us at the All-In Holiday Spectacular!:
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Referenced in the show:
https://x.com/RepClayHiggins/status/1990868089056219267
https://x.com/michaeljburry/status/1991289193037746579
https://polymarket.com/event/which-company-has-best-ai-model-end-of-2025
(0:00) Michael Burry's big short against AI
(12:00) Why Palantir is so richly valued vs other tech companies
(20:07) Home affordability crisis: Mortgage innovation, building, top priorities to win mid-terms
(36:18) H-1B debate flares up again after Trump's comments on Fox News
(42:37) Science Corner: Solar storms, coronal mass ejection, risks
(51:14) Rich Americans fleeing "the great confiscation"
Join us at the All-In Holiday Spectacular!:
https://allin.com/events
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https://rb.gy/tppkzl
https://x.com/yung_spielburg
Intro Video Credit:
https://x.com/TheZachEffect
Referenced in the show:
https://x.com/michaeljburry/status/1988778952299802818
https://x.com/_Investinq/status/1988847716613365845
https://x.com/michaeljburry/status/1987918650104283372
https://www.nytimes.com/2025/11/06/realestate/first-time-home-buyers.html
https://x.com/jatanackov/status/1988256651103592564
https://x.com/omapproach/status/1988410644907856075
https://x.com/latestinspace/status/1988606899932299700
https://www.swpc.noaa.gov/
(0:00) Brad Gerstner joins the show!
(0:49) OpenAI's rough week: Altman's controversial comments on BG2, CFO's "federal backstop" faux pas, clarifications
(18:33) Why Jensen Huang said "China is going to win the AI race."; the need for a federal framework on AI
(30:39) OpenAI's strengths and headwinds: breakout product, trust issues, competition, betting on the AI supercycle
(36:47) Holiday party announcement! allin.com/events for tickets
(39:19) State of the market, consumer is cracking, need for domestic/"main street" wins, is Trump losing the middle class?
(1:05:58) Zohran wins NYC, socialism's rise in America, solutions, should Republicans end the filibuster?
Join us at the All-In Holiday Spectacular!:
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Referenced in the show:
https://www.cnbc.com/2025/10/29/alphabet-google-q3-earnings.html
https://www.cnbc.com/2025/10/29/meta-q3-earnings-report-2025.html
https://www.linkedin.com/feed/update/urn:li:activity:7392049356012507136/
https://x.com/DavidSacks/status/1986476840207122440
https://x.com/sama/status/1986514377470845007
https://www.ft.com/content/53295276-ba8d-4ec2-b0de-081e73b3ba43
https://x.com/nvidianewsroom/status/1986221177099194484
https://www.aipanic.news/p/the-ai-existential-risk-industrial
https://fred.stlouisfed.org/series/LES1252881600Q
https://x.com/MorningBrew/status/1986464568470888935
https://x.com/chamath/status/1986076707196162068
https://polymarket.com/event/new-york-city-mayoral-election
https://www.nbcnews.com/politics/2025-elections/new-york-city-mayor-results
(0:00) Introducing Ari Emanuel
(1:03) Ari's background in the content business and Hollywood
(4:14) How infinite distribution is changing Hollywood, the future of podcasting, creators owning advertising products
(9:21) AI's impact: anticipating the 3-day workweek
(12:13) Splitting time between TKO and WME, YouTube vs Netflix for creators, modern IP ownership
(18:20) How he got a fighter's reputation, relationship with Michael Ovitz, how he built on Ovitz's vision
(22:12) Future of sports entertainment: adapting to attention spans, clip culture, going global
(24:21) Ari's relationship with his brothers and Elon Musk
Thanks to our partners for making this happen!
Solana - Solana is the high performance network powering internet capital markets, payments, and crypto applications. Connect with investors, crypto founders, and entrepreneurs at Solana's global flagship event during Abu Dhabi Finance Week & F1: https://solana.com/breakpoint
OKX - The new way to build your crypto portfolio and use it in daily life. We call it the new money app. https://www.okx.com/
Google Cloud - The next generation of unicorns is building on Google Cloud's industry-leading, fully integrated AI stack: infrastructure, platform, models, agents, and data. https://cloud.google.com/
IREN - IREN AI Cloud, powered by NVIDIA GPUs, provides the scale, performance, and reliability to accelerate your AI journey. https://iren.com/
Oracle - Step into the future of enterprise productivity at Oracle AI Experience Live. https://www.oracle.com/artificial-intelligence/data-ai-events/
Circle - The America-based company behind USDC ? a fully-reserved, enterprise-grade stablecoin at the core of the emerging internet financial system. https://www.circle.com/
BVNK - Building stablecoin-powered financial infrastructure that helps businesses send, store, and spend value instantly, anywhere in the world. https://www.bvnk.com/
Polymarket - The world's largest prediction market. https://www.polymarket.com/
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(0:00) Introducing Tareq Amin
(0:39) Saudi Arabia's evolution, Humain's business
(8:11) How Humain works with foundational model providers
(13:14) Saudi's energy and talent advantages, the AI race in the Middle East
(18:11) Working in the era of MBS, Vision 2030
(21:40) How Saudi manages their relationships with the US and China
(23:51) Sacks on the US-Saudi AI alliance
Thanks to our partners for making this happen!
Solana - Solana is the high performance network powering internet capital markets, payments, and crypto applications. Connect with investors, crypto founders, and entrepreneurs at Solana's global flagship event during Abu Dhabi Finance Week & F1: https://solana.com/breakpoint
OKX - The new way to build your crypto portfolio and use it in daily life. We call it the new money app. https://www.okx.com/
Google Cloud - The next generation of unicorns is building on Google Cloud's industry-leading, fully integrated AI stack: infrastructure, platform, models, agents, and data. https://cloud.google.com/
IREN - IREN AI Cloud, powered by NVIDIA GPUs, provides the scale, performance, and reliability to accelerate your AI journey. https://iren.com/
Oracle - Step into the future of enterprise productivity at Oracle AI Experience Live. https://www.oracle.com/artificial-intelligence/data-ai-events/
Circle - The America-based company behind USDC ? a fully-reserved, enterprise-grade stablecoin at the core of the emerging internet financial system. https://www.circle.com/
BVNK - Building stablecoin-powered financial infrastructure that helps businesses send, store, and spend value instantly, anywhere in the world. https://www.bvnk.com/
Polymarket - The world's largest prediction market. https://www.polymarket.com/
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(0:00) Introducing Paul "Triple H" Levesque
(0:56) The skills needed to be an effective professional wrestler, understanding the characteristics of President Trump and The Rock
(5:41) The rise of the antihero / heel persona, and why modern wrestling is more morally grey
(8:43) WWE vs UFC: Why they are opposites, star building
(11:21) Physicality of the WWE and how they support wrestlers
(14:13) The business of the WWE: using streaming and social as a funnel for live events, the magic of live WWE
(21:28) Helping America's youth via physical fitness
(23:35) How the internet forced wrestlers to blend their in ring personas with real-life
Thanks to our partners for making this happen!
Solana - Solana is the high performance network powering internet capital markets, payments, and crypto applications. Connect with investors, crypto founders, and entrepreneurs at Solana's global flagship event during Abu Dhabi Finance Week & F1: https://solana.com/breakpoint
OKX - The new way to build your crypto portfolio and use it in daily life. We call it the new money app. https://www.okx.com/
Google Cloud - The next generation of unicorns is building on Google Cloud's industry-leading, fully integrated AI stack: infrastructure, platform, models, agents, and data. https://cloud.google.com/
IREN - IREN AI Cloud, powered by NVIDIA GPUs, provides the scale, performance, and reliability to accelerate your AI journey. https://iren.com/
Oracle - Step into the future of enterprise productivity at Oracle AI Experience Live. https://www.oracle.com/artificial-intelligence/data-ai-events/
Circle - The America-based company behind USDC ? a fully-reserved, enterprise-grade stablecoin at the core of the emerging internet financial system. https://www.circle.com/
BVNK - Building stablecoin-powered financial infrastructure that helps businesses send, store, and spend value instantly, anywhere in the world. https://www.bvnk.com/
Polymarket - The world's largest prediction market. https://www.polymarket.com/
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(0:00) Disgraziad Corner: The most disgraceful things of the week!
(3:10) Elon on X's new algorithm, why there has been so much Sydney Sweeney content lately
(11:35) Creating Grokipedia: Wikipedia's failures, the future of information on the internet, confirmation bias
(24:52) Three years of X: Looking back on the Twitter acquisition and how it changed free speech on the internet
(42:49) Tesla vote on Elon's compensation, would he leave Tesla if it doesn't pass?
(47:40) OpenAI lawsuit, for-profit conversion, how much Elon should own, OpenAI's great irony
(56:24) AI power efficiency, Robotaxis, future of self-driving
(1:09:34) Bill Gates flips on climate change, solar, energy production
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(0:00) Chamath and Jason welcome Pete Buttigieg
(1:31) Why the Democrats lost tech
(6:40) Taxes: Federal wealth tax, wealth disparity, billionaires, the role of government in the free market
(23:17) Government efficiency: Democratic DOGE, breaking ranks on debt, his plan to control spending
(33:01) Culture Wars: The costly role of democratic identity politics, navigating a primary with moderate views, the two Democratic Parties
(40:07) Immigration: Trump shutting the border, Biden's failure
(47:38) Working in the Biden Admin: good and bad, gatekeepers, cognitive decline, anointing Kamala Harris vs running a short primary
(52:17) Thoughts on moving NASA under the Dept of Transportation
(54:07) AI: self-driving, automation, and job loss
(1:01:19) Running in 2028, Mamdani in NYC
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(0:00) Friedberg introduces 2025 Nobel Peace Prize Winner María Corina Machado
(4:27) Venezuela before and after Chavez
(15:25) Why María got involved in politics and why she was expelled
(24:33) Why Maduro was chosen and Chavez's successor, China relationship, why people are fleeing
(31:27) Intimidation tactics by the Maduro regime, response to claims of her being a "Western puppet"
(39:30) Presidential run, election fraud, how different US regimes have viewed Venezuela
(54:23) The rise of socialism in the US
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Learn more about the 2025 Nobel Peace Prize:
https://www.nobelpeaceprize.org/articles/nobels-fredspris-2025-1
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(0:00) David Friedberg intros John Martinis, the 2025 recipient of the Nobel Prize in Physics
(0:43) John's history, how he got into physics
(4:54) Explainer on quantum mechanics
(22:57) Quantum tunneling and the 1985 paper that led to this Nobel Prize
(30:37) Understanding qubits, the state of quantum computing, and the impact of AI
(40:56) US vs China in quantum, reactions to winning the Nobel Prize
Learn more about the 2025 Nobel Prize in Physics:
https://www.nobelprize.org/prizes/physics/2025/summary
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(0:00) Bestie intros!
(1:02) CA Billionaire Tax
(17:00) Major NBA gambling scandal
(29:51) Amazon's eventful week: AWS outage and leaked robotic automation plans
(49:55) Tesla earnings, Optimus, Elon's pay package, "corporate terrorists"
(1:03:54) Study shows AI bias
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Referenced in the show:
https://www.thefp.com/p/rick-caruso-refuses-to-shake-jeffrey-katzenbergs-hand
https://www.cnbc.com/2025/10/23/nba-billups-rozier-sports-betting-arrests-gambling.html
https://oag.ca.gov/system/files/initiatives/pdfs/25-0024%20%28Billionaire%20Tax%20%29.pdf
https://x.com/MovieTimeDev/status/1968107643643498744
https://x.com/SawyerMerritt/status/1981119824991322553
https://www.nytimes.com/live/2025/10/23/nyregion/nba-illegal-gambling-arrests
https://x.com/AndrewDBailey/status/1981409771505713650
https://seekingalpha.com/article/4832142-tesla-inc-tsla-q3-2025-earnings-call-transcript
https://x.com/shayne_coplan/status/1981016949309239616
(0:00) Chamath and Jason welcome Senator Joe Manchin!
(4:20) Blocking Build Back Better, defending the filibuster while dealing with paid protestors and death threats
(19:39) How Biden's staff pushed him to the far left, mental acuity, how he "lost the will to fight," why Obama was an "elusive" president
(28:12) Why socialism is on the rise in America, entitlement culture
(37:06) Importance of term limits in Congress, Joe's favorite current senators, cascading issues from the loss of bipartisanship
(52:25) Breaking the Dem/Rep duopoly by opening up primaries, thoughts on midterms in 2026
(57:18) Expectation vs reality for Obama, Trump and Biden presidencies; thoughts on the 2028 election
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(0:00) Introducing Jan Sramek
(0:51) How California Forever is building America's next great city
Thanks to our partners for making this happen!
Solana - Solana is the high performance network powering internet capital markets, payments, and crypto applications. Connect with investors, crypto founders, and entrepreneurs at Solana's global flagship event during Abu Dhabi Finance Week & F1: https://solana.com/breakpoint
OKX - The new way to build your crypto portfolio and use it in daily life. We call it the new money app. https://www.okx.com/
Google Cloud - The next generation of unicorns is building on Google Cloud's industry-leading, fully integrated AI stack: infrastructure, platform, models, agents, and data. https://cloud.google.com/
IREN - IREN AI Cloud, powered by NVIDIA GPUs, provides the scale, performance, and reliability to accelerate your AI journey. https://iren.com/
Oracle - Step into the future of enterprise productivity at Oracle AI Experience Live. https://www.oracle.com/artificial-intelligence/data-ai-events/
Circle - The America-based company behind USDC ? a fully-reserved, enterprise-grade stablecoin at the core of the emerging internet financial system. https://www.circle.com/
BVNK - Building stablecoin-powered financial infrastructure that helps businesses send, store, and spend value instantly, anywhere in the world. https://www.bvnk.com/
Polymarket - The world's largest prediction market. https://www.polymarket.com/
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(0:00) Bestie intros! Dreamforce and another interesting conference take the Bay Area
(3:35) State of crime in SF, do they need the National Guard?
(20:48) US to impose price floors after China puts export controls on rare earths, can America on-shore a full-stack rare earth industry?
(36:15) State of US-China ahead of the Trump-Xi meeting, how we got here, China's elite mercantilism and strong economic history
(52:59) AI PR crisis: Recent datacenters get denied
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Intro Music Credit:
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Referenced in the show:
https://www.nytimes.com/2025/10/10/us/marc-benioff-san-francisco-guard.html
https://www.wsj.com/opinion/san-francisco-cleans-up-for-xi-why-not-for-thee-242c67e3
https://x.com/the_jefferymead/status/1978130345200427334
https://www.ft.com/content/ca3b3254-e161-41d1-b459-bc3c83004e4e
https://www.nytimes.com/2025/10/12/business/china-rare-earth-export-controls.html
https://truthsocial.com/@realDonaldTrump/posts/115351840469973590
https://truthsocial.com/@realDonaldTrump/posts/115350455734003647
https://mpmaterials.com/mountain-pass
https://www.reuters.com/world/china/trump-track-meet-xi-south-korea-bessent-says-2025-10-13/
https://chinapower.csis.org/tracker/china-gdp
https://www.amazon.com/Lee-Kuan-Yew-Insights-international/dp/0262019124
https://www.mearsheimer.com/wp-content/uploads/2019/06/The-Australian-November-18-2005.pdf
https://nationalinterest.org/feature/can-china-rise-peacefully-10204
https://www.jdsupra.com/legalnews/commerce-department-issues-affiliates-5215830/
https://www.amazon.com/End-History-Last-Man/dp/0743284550
https://www.amazon.com/Clash-Civilizations-Remaking-World-Order/dp/1451628978
https://www.amazon.com/World-Flat-History-Twenty-first-Century/dp/0374292884
https://x.com/balajis/status/1937517664907460980
https://x.com/chamath/status/1978584886329082098
(0:00) Chamath and Friedberg welcome Andrew Ross Sorkin to discuss his new book, "1929: Inside the Greatest Crash in Wall Street History--and How It Shattered a Nation"
(0:38) Why he chose this time period
(3:22) The setup: what led to the 1929 crash
(19:24) The characters: major players in the 1929 crash; what kind of bubble are we experiencing in 2025?
(26:21) Role of journalist vs market participant; characters of the 2025 market
(30:10) AI's potential 1929-like impact on unemployment
(35:16) Why socialism is flaring up now more than it did post-1929
(40:34) Does the US need a 2025 "New Deal" on cutting spending, tariff balancing act
(46:51) Film rights strategy
Buy Sorkin's new book:
https://www.amazon.com/1929-Inside-Greatest-History-Shattered/dp/0593296966
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Referenced in the show:
https://www.amazon.com/1929-Inside-Greatest-History-Shattered/dp/0593296966
https://archive.org/details/sim_ladies-home-journal_1929-08_46_8/page/n9/mode/2up
(0:00) Introducing Orlando Bravo
(1:53) Orlando's history, Puerto Rico origins, how he got into private equity
(7:10) How he runs Thoma Bravo: small team, outward facing, mentorship, patience in fundraising
(9:01) Role of PE in the American economy, public perception, underwriting AI risks
(15:23) Deal pricing philosophy, acquiring Boeing's avionics business
(19:24) Thoma Bravo's operating playbook after acquiring a company
(26:16) Thoughts on taking Thoma Bravo public
Thanks to our partners for making this happen!
Solana - Solana is the high performance network powering internet capital markets, payments, and crypto applications. Connect with investors, crypto founders, and entrepreneurs at Solana's global flagship event during Abu Dhabi Finance Week & F1: https://solana.com/breakpoint
OKX - The new way to build your crypto portfolio and use it in daily life. We call it the new money app. https://www.okx.com/
Google Cloud - The next generation of unicorns is building on Google Cloud's industry-leading, fully integrated AI stack: infrastructure, platform, models, agents, and data. https://cloud.google.com/
IREN - IREN AI Cloud, powered by NVIDIA GPUs, provides the scale, performance, and reliability to accelerate your AI journey. https://iren.com/
Oracle - Step into the future of enterprise productivity at Oracle AI Experience Live. https://www.oracle.com/artificial-intelligence/data-ai-events/
Circle - The America-based company behind USDC ? a fully-reserved, enterprise-grade stablecoin at the core of the emerging internet financial system. https://www.circle.com/
BVNK - Building stablecoin-powered financial infrastructure that helps businesses send, store, and spend value instantly, anywhere in the world. https://www.bvnk.com/
Polymarket - The world's largest prediction market. https://www.polymarket.com/
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Intro Music Credit:
(0:00) Introducing Bryan Johnson
(0:46) Bryan takes the audience through a quick biological age test
(5:53) The single best longevity hack from all of his research
Thanks to our partners for making this happen!
Solana - Solana is the high performance network powering internet capital markets, payments, and crypto applications. Connect with investors, crypto founders, and entrepreneurs at Solana's global flagship event during Abu Dhabi Finance Week & F1: https://solana.com/breakpoint
OKX - The new way to build your crypto portfolio and use it in daily life. We call it the new money app. https://www.okx.com/
Google Cloud - The next generation of unicorns is building on Google Cloud's industry-leading, fully integrated AI stack: infrastructure, platform, models, agents, and data. https://cloud.google.com/
IREN - IREN AI Cloud, powered by NVIDIA GPUs, provides the scale, performance, and reliability to accelerate your AI journey. https://iren.com/
Oracle - Step into the future of enterprise productivity at Oracle AI Experience Live. https://www.oracle.com/artificial-intelligence/data-ai-events/
Circle - The America-based company behind USDC ? a fully-reserved, enterprise-grade stablecoin at the core of the emerging internet financial system. https://www.circle.com/
BVNK - Building stablecoin-powered financial infrastructure that helps businesses send, store, and spend value instantly, anywhere in the world. https://www.bvnk.com/
Polymarket - The world's largest prediction market. https://www.polymarket.com/
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Intro Music Credit:
(0:00) Introducing Cathie Wood
(0:47) Cathie Wood on AI's once in a lifetime opportunity: doubling GDP, deflation, and more
(9:23) Cathie's bull case for Bitcoin $1M
(11:38) Opening up access to innovation for retail
(14:32) Cathie explains Ark's strategies for bull and bear markets
(16:01) Thoughts on Elon's trillion-dollar pay package
Thanks to our partners for making this happen!
Solana - Solana is the high performance network powering internet capital markets, payments, and crypto applications. Connect with investors, crypto founders, and entrepreneurs at Solana's global flagship event during Abu Dhabi Finance Week & F1: https://solana.com/breakpoint
OKX - The new way to build your crypto portfolio and use it in daily life. We call it the new money app. https://www.okx.com/
Google Cloud - The next generation of unicorns is building on Google Cloud's industry-leading, fully integrated AI stack: infrastructure, platform, models, agents, and data. https://cloud.google.com/
IREN - IREN AI Cloud, powered by NVIDIA GPUs, provides the scale, performance, and reliability to accelerate your AI journey. https://iren.com/
Oracle - Step into the future of enterprise productivity at Oracle AI Experience Live. https://www.oracle.com/artificial-intelligence/data-ai-events/
Circle - The America-based company behind USDC ? a fully-reserved, enterprise-grade stablecoin at the core of the emerging internet financial system. https://www.circle.com/
BVNK - Building stablecoin-powered financial infrastructure that helps businesses send, store, and spend value instantly, anywhere in the world. https://www.bvnk.com/
Polymarket - The world's largest prediction market. https://www.polymarket.com/
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Intro Music Credit:
(0:00) Bestie intros: Welcome back Brad Gerstner!
(2:48) Israel-Hamas ceasefire, how Trump and his team got the deal done
(13:27) National Guard sent to Chicago to protect ICE Agents
(44:02) OpenAI's deal with AMD, state of the "AI Bubble"
(1:05:45) Circular AI deals: cause for concern or no big deal?
(1:15:00) What's behind the Gold rally?
(1:20:38) Polymarket receives $2B investment from NYSE owner ICE, future of prediction markets
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Intro Music Credit:
Intro Video Credit:
Referenced in the show:
https://truthsocial.com/@realDonaldTrump/posts/115340993884364431
https://x.com/RapidResponse47/status/1972726021196562494
https://x.com/JasonJournoDC/status/1976080696209760487
https://www.washingtonpost.com/opinions/2025/10/09/gaza-ceasefire-deal-trump-nobel-prize
https://x.com/BillAckman/status/1976307397099471229
https://polymarket.com/event/will-hamas-release-all-israeli-hostages-by-october-31?tid=1760021581013
https://www.newsweek.com/ice-rappel-black-hawk-helicopters-chicago-10809228
https://x.com/libsoftiktok/status/1965294885373947928
https://x.com/CollinRugg/status/1972716966831120601
https://x.com/unlimited_ls/status/1975302286969631204
https://www.newsweek.com/donald-trumps-approval-rating-boost-cities-crime-crackdown-10840101
https://www.washingtonpost.com/dc-md-va/2025/08/20/dc-poll-trump-crime-police/
https://x.com/wallstreetapes/status/1976030014614421936
https://x.com/ericldaugh/status/1976020869752508907
https://www.wsj.com/tech/ai/openai-amd-deal-ai-chips-ed92cc42
https://finance.yahoo.com/news/tether-gold-xaut-hits-1b-080222337.html
https://www.cnbc.com/2025/10/07/nyse-owner-intercontinental-exchange-2-billion-polymarket-stake.html
https://polymarket.com/event/will-polymarket-us-go-live-in-2025?tid=1760113275545
(0:00) Introducing Roelof Botha
(1:08) Sequoia's Scout program and its best-performing funds ever
(3:38) State of Venture Capital: Why it's broken, too much capital, not enough great companies
(9:01) Why Sequoia separated from its China business, how they adapt to changing macro landscapes
(13:05) Sequoia's culture, picking partners, investment decision-making, The Sequoia Capital Fund and holding winners
(20:18) What makes a great founder, what Roelof learned from Doug Leone and Michael Moritz
(26:06) Investing in biotech, importance of expertise in VC
Thanks to our partners for making this happen!
Solana - Solana is the high performance network powering internet capital markets, payments, and crypto applications. Connect with investors, crypto founders, and entrepreneurs at Solana's global flagship event during Abu Dhabi Finance Week & F1: https://solana.com/breakpoint
OKX - The new way to build your crypto portfolio and use it in daily life. We call it the new money app. https://www.okx.com/
Google Cloud - The next generation of unicorns is building on Google Cloud's industry-leading, fully integrated AI stack: infrastructure, platform, models, agents, and data. https://cloud.google.com/
IREN - IREN AI Cloud, powered by NVIDIA GPUs, provides the scale, performance, and reliability to accelerate your AI journey. https://iren.com/
Oracle - Step into the future of enterprise productivity at Oracle AI Experience Live. https://www.oracle.com/artificial-intelligence/data-ai-events/
Circle - The America-based company behind USDC ? a fully-reserved, enterprise-grade stablecoin at the core of the emerging internet financial system. https://www.circle.com/
BVNK - Building stablecoin-powered financial infrastructure that helps businesses send, store, and spend value instantly, anywhere in the world. https://www.bvnk.com/
Polymarket - The world's largest prediction market. https://www.polymarket.com/
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Intro Music Credit:
(0:00) Introducing YouTube CEO Neal Mohan
(1:08) YouTube's revenue split with creators
(7:30) How Neal thinks about enabling monoculture and connective threads at YouTube
(11:23) Censorship on YouTube, demonetization decisions, dealing with different regimes and laws globally
(19:58) YouTube TV, YouTube Premium, and channel subscriptions
(24:00) Generative AI on YouTube: labeling AI, likeness concerns, possibilities
Thanks to our partners for making this happen!
Solana - Solana is the high performance network powering internet capital markets, payments, and crypto applications. Connect with investors, crypto founders, and entrepreneurs at Solana's global flagship event during Abu Dhabi Finance Week & F1: https://solana.com/breakpoint
OKX - The new way to build your crypto portfolio and use it in daily life. We call it the new money app. https://www.okx.com/
Google Cloud - The next generation of unicorns is building on Google Cloud's industry-leading, fully integrated AI stack: infrastructure, platform, models, agents, and data. https://cloud.google.com/
IREN - IREN AI Cloud, powered by NVIDIA GPUs, provides the scale, performance, and reliability to accelerate your AI journey. https://iren.com/
Oracle - Step into the future of enterprise productivity at Oracle AI Experience Live. https://www.oracle.com/artificial-intelligence/data-ai-events/
Circle - The America-based company behind USDC ? a fully-reserved, enterprise-grade stablecoin at the core of the emerging internet financial system. https://www.circle.com/
BVNK - Building stablecoin-powered financial infrastructure that helps businesses send, store, and spend value instantly, anywhere in the world. https://www.bvnk.com/
Polymarket - https://www.polymarket.com/
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Intro Music Credit:
(0:00) Introducing Joe Tsai
(0:49) Owning the Nets and Liberty, Caitlin Clark's impact on the WNBA, does the NBA need fixing?
(6:07) Alibaba origins, China's pullback on capitalism
(10:10) US vs China rivalry: the AI race, are we destined for conflict, and what can the US learn from China?
(19:46) AI application in large businesses
(21:52) Managing corporate culture at Alibaba's scale, Nets predictions
(23:17) AI adoption, job anxiety, and AGI views in China
Thanks to our partners for making this happen!
Solana - Solana is the high performance network powering internet capital markets, payments, and crypto applications. Connect with investors, crypto founders, and entrepreneurs at Solana's global flagship event during Abu Dhabi Finance Week & F1: https://solana.com/breakpoint
OKX - The new way to build your crypto portfolio and use it in daily life. We call it the new money app. https://www.okx.com/
Google Cloud - The next generation of unicorns is building on Google Cloud's industry-leading, fully integrated AI stack: infrastructure, platform, models, agents, and data. https://cloud.google.com/
IREN - IREN AI Cloud, powered by NVIDIA GPUs, provides the scale, performance, and reliability to accelerate your AI journey. https://iren.com/
Oracle - Step into the future of enterprise productivity at Oracle AI Experience Live. https://www.oracle.com/artificial-intelligence/data-ai-events/
Circle - The America-based company behind USDC ? a fully-reserved, enterprise-grade stablecoin at the core of the emerging internet financial system. https://www.circle.com/
BVNK - Building stablecoin-powered financial infrastructure that helps businesses send, store, and spend value instantly, anywhere in the world. https://www.bvnk.com/
Polymarket - https://www.polymarket.com/
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Intro Music Credit:
(0:00) Bestie intros!
(1:53) EA acquired for $55B in biggest LBO ever, why PE is in trouble
(17:42) IPO market, SPAC 2.0
(27:41) The AI rollup opportunity
(36:01) Sacks joins the show!
(38:27) OpenAI and Meta launch short-form video apps: "AI Slop" or the future of content?
(45:04) Open source AI: DeepSeek's new model, pressure on US AI industry
(1:05:11) State AI regulation frenzy: States' rights vs Federal control, overregulation
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Intro Music Credit:
Intro Video Credit:
Referenced in the show:
https://x.com/Jason/status/1973461806585966655
https://www.npr.org/2025/09/05/nx-s1-5529404/anthropic-settlement-authors-copyright-ai
(0:00) Chamath and Jason welcome Rep. Ro Khanna!
(1:10) H-1Bs and immigration
(8:40) Giving Trump credit as a Progressive Democrat, why bipartisanship is broken, future Democratic leaders
(15:08) Tech industry: Can Democrats win back tech?; Economic patriotism, protection vs proliferation of AI
(24:25) Government shutdown, what actually happens?
(30:25) Extreme rhetoric: Importance of dialing this down
(36:29) Censorship and lawfare on both sides
(40:32) Crime issues in major cities, why Democrats are losing on safety, common sense solutions
(47:46) Mamdani's surge: is Zohran the future of the party?
(51:15) Congressional stock trading ban
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Intro Music Credit:
Intro Video Credit:
(0:00) Introducing Kyle Samani
(1:07) History of modern capital markets
(3:25) What a redesigned capital market structure would look like in 2025
(8:22) Examples of the future of internet capital markets
Thanks to our partners for making this happen!
Solana - Solana is the high performance network powering internet capital markets, payments, and crypto applications. Connect with investors, crypto founders, and entrepreneurs at Solana's global flagship event during Abu Dhabi Finance Week & F1: https://solana.com/breakpoint
OKX - The new way to build your crypto portfolio and use it in daily life. We call it the new money app. https://www.okx.com/
Google Cloud - The next generation of unicorns is building on Google Cloud's industry-leading, fully integrated AI stack: infrastructure, platform, models, agents, and data. https://cloud.google.com/
IREN - IREN AI Cloud, powered by NVIDIA GPUs, provides the scale, performance, and reliability to accelerate your AI journey. https://iren.com/
Oracle - Step into the future of enterprise productivity at Oracle AI Experience Live. https://www.oracle.com/artificial-intelligence/data-ai-events/
Circle - The America-based company behind USDC ? a fully-reserved, enterprise-grade stablecoin at the core of the emerging internet financial system. https://www.circle.com/
BVNK - Building stablecoin-powered financial infrastructure that helps businesses send, store, and spend value instantly, anywhere in the world. https://www.bvnk.com/
Polymarket - https://www.polymarket.com/
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Intro Music Credit:
(0:00) Introducing Rick Caruso
(1:03) Reflecting on the disastrous LA Wildfires: Karen Bass failure, saving the Palisades Village, failure to rebuild
(11:20) California's incompetence, running for CA Governor vs LA Mayor
(14:21) Attention to detail
(17:04) State of California: What it should be, homelessness, National Guard, policing
Thanks to our partners for making this happen!
Solana - Solana is the high performance network powering internet capital markets, payments, and crypto applications. Connect with investors, crypto founders, and entrepreneurs at Solana's global flagship event during Abu Dhabi Finance Week & F1: https://solana.com/breakpoint
OKX - The new way to build your crypto portfolio and use it in daily life. We call it the new money app. https://www.okx.com/
Google Cloud - The next generation of unicorns is building on Google Cloud's industry-leading, fully integrated AI stack: infrastructure, platform, models, agents, and data. https://cloud.google.com/
IREN - IREN AI Cloud, powered by NVIDIA GPUs, provides the scale, performance, and reliability to accelerate your AI journey. https://iren.com/
Oracle - Step into the future of enterprise productivity at Oracle AI Experience Live. https://www.oracle.com/artificial-intelligence/data-ai-events/
Circle - The America-based company behind USDC ? a fully-reserved, enterprise-grade stablecoin at the core of the emerging internet financial system. https://www.circle.com/
BVNK - Building stablecoin-powered financial infrastructure that helps businesses send, store, and spend value instantly, anywhere in the world. https://www.bvnk.com/
Polymarket - https://www.polymarket.com/
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Intro Music Credit:
(0:00) Introducing Arm CEO Rene Haas
(1:08) Lessons from working with Jensen Huang
(3:20) Arm's history, understanding Nvidia's dominance in AI, training vs inference, physical AI market size
(10:01) China's AI ecosystem, the US-Intel deal, rare earths, creating a US "national champion"
(15:35) Manufacturing in America: how to create a culture of excellence?
(18:34) US export controls, building in the UK
(23:42) US-China AI arms race
Thanks to our partners for making this happen!
Solana - Solana is the high performance network powering internet capital markets, payments, and crypto applications. Connect with investors, crypto founders, and entrepreneurs at Solana's global flagship event during Abu Dhabi Finance Week & F1: https://solana.com/breakpoint
OKX - The new way to build your crypto portfolio and use it in daily life. We call it the new money app. https://www.okx.com/
Google Cloud - The next generation of unicorns is building on Google Cloud's industry-leading, fully integrated AI stack: infrastructure, platform, models, agents, and data. https://cloud.google.com/
IREN - IREN AI Cloud, powered by NVIDIA GPUs, provides the scale, performance, and reliability to accelerate your AI journey. https://iren.com/
Oracle - Step into the future of enterprise productivity at Oracle AI Experience Live. https://www.oracle.com/artificial-intelligence/data-ai-events/
Circle - The America-based company behind USDC ? a fully-reserved, enterprise-grade stablecoin at the core of the emerging internet financial system. https://www.circle.com/
BVNK - Building stablecoin-powered financial infrastructure that helps businesses send, store, and spend value instantly, anywhere in the world. https://www.bvnk.com/
Polymarket: https://www.polymarket.com
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Intro Music Credit:
(0:00) Introducing Cleo Abram
(1:12) Why YouTube has become the best platform for creators, techno-optimism at Huge If True
(8:35) Astrophysicist Alex Filippenko on the James Webb Space Telescope
(23:14) Q&A with Alex Filippenko, Cleo, and Friedberg: The universe, Fermi Paradox, black holes, NIH grants and the "war on science"
(37:37) Zipline CEO Keller Rinaudo Cliffton on the future of drone delivery
(53:29) Q&A with Keller Rinaudo Cliffton, Cleo, and Friedberg: Instant delivery explosion, competitors, impact on healthcare
Thanks to our partners for making this happen!
Solana - Solana is the high performance network powering internet capital markets, payments, and crypto applications. Connect with investors, crypto founders, and entrepreneurs at Solana's global flagship event during Abu Dhabi Finance Week & F1: https://solana.com/breakpoint
OKX - The new way to build your crypto portfolio and use it in daily life. We call it the new money app. https://www.okx.com/
Google Cloud - The next generation of unicorns is building on Google Cloud's industry-leading, fully integrated AI stack: infrastructure, platform, models, agents, and data. https://cloud.google.com/
IREN - IREN AI Cloud, powered by NVIDIA GPUs, provides the scale, performance, and reliability to accelerate your AI journey. https://iren.com/
Oracle - Step into the future of enterprise productivity at Oracle AI Experience Live. https://www.oracle.com/artificial-intelligence/data-ai-events/
Circle - The America-based company behind USDC ? a fully-reserved, enterprise-grade stablecoin at the core of the emerging internet financial system. https://www.circle.com/
BVNK - Building stablecoin-powered financial infrastructure that helps businesses send, store, and spend value instantly, anywhere in the world. https://www.bvnk.com/
Polymarket - https://www.polymarket.com/
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Intro Music Credit:
(0:00) Introducing Eli Lilly CEO Dave Ricks
(1:43) How Eli Lilly discovered the GLP-1 impact on weight loss, counterfeit products from China
(7:08) GLP-1 pricing and capital allocation after a breakout pharma product
(12:56) Why Biotech VC has plummeted, "patent hacking" in China
(15:32) Dave's health regimen: good sleep, movement, healthy diet, social relationships, reading
(18:32) Unexpected impacts of GLP-1s, helping with addictions, potential mental health use cases
(21:16) Thoughts on RFK Jr, Big Pharma's influence on the media, how AI empowers patients
(25:27) Impact of proposed NIH cuts, explaining the "PBM boogeyman", next major pharma breakthrough
Thanks to our partners for making this happen!
Solana - Solana is the high performance network powering internet capital markets, payments, and crypto applications. Connect with investors, crypto founders, and entrepreneurs at Solana's global flagship event during Abu Dhabi Finance Week & F1: https://solana.com/breakpoint
OKX - The new way to build your crypto portfolio and use it in daily life. We call it the new money app. https://www.okx.com/
Google Cloud - The next generation of unicorns is building on Google Cloud's industry-leading, fully integrated AI stack: infrastructure, platform, models, agents, and data. https://cloud.google.com/
IREN - IREN AI Cloud, powered by NVIDIA GPUs, provides the scale, performance, and reliability to accelerate your AI journey. https://iren.com/
Oracle - Step into the future of enterprise productivity at Oracle AI Experience Live. https://www.oracle.com/artificial-intelligence/data-ai-events/
Circle - The America-based company behind USDC ? a fully-reserved, enterprise-grade stablecoin at the core of the emerging internet financial system. https://www.circle.com/
BVNK - Building stablecoin-powered financial infrastructure that helps businesses send, store, and spend value instantly, anywhere in the world. https://www.bvnk.com/
Polymarket: https://www.polymarket.com/
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Intro Music Credit:
(0:00) Bestie intros!
(2:23) H-1B overhaul: origins and exploitation
(25:26) Autism linked to Tylenol usage during pregnancy
(43:42) Jimmy Kimmel returns to ABC: comments and reactions
(59:21) Two major AI papers
(1:09:00) YouTube update
(1:12:53) Alphabet admits to COVID censorship under Biden, new CA online hate speech law
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Intro Music Credit:
Intro Video Credit:
Referenced in the show:
https://polymarket.com/event/will-courts-block-trumps-100k-h1b-by-september-30
https://www.cnbc.com/2015/08/18/trump-sort-of-right-on-silicon-valley-visas-calacanis.html
https://x.com/RobertMSterling/status/1873174358535110953
https://www.firstpost.com/explainers/deepseek-employees-travel-ban-china-13872040.html
https://www.axios.com/2019/12/29/trump-att-outsourcing-h1b-visa-foreign-workers
https://hub.jhu.edu/2019/11/05/acetaminophen-pregnancy-autism-adhd/
https://x.com/ThaaatColin/status/1958690862185230539
https://x.com/ThaaatColin/status/1958690862185230539
https://polymarket.com/event/jimmy-kimmel-out-by-september-30?tid=1758935046582
https://x.com/sahilkapur/status/1970211641124847711
https://x.com/shawn_farash/status/1971289990283002022
https://x.com/Scott_Wiener/status/1970307297999007773
https://x.com/thackerpd/status/1971246303243010172
https://support.google.com/youtube/answer/7354993?hl=en
(0:00) Introducing Eric Schmidt
(1:59) Thoughts on remote work and work-life balance
(3:49) Approaching AI: US vs China
(8:04) Relativity Space, rockets, drones, defense, and more
(17:32) Future role of America, and the decline of the West
(21:51) AGI: boom or bust?
Thanks to our partners for making this happen!
Solana - Solana is the high performance network powering internet capital markets, payments, and crypto applications. Connect with investors, crypto founders, and entrepreneurs at Solana's global flagship event during Abu Dhabi Finance Week & F1: https://solana.com/breakpoint
OKX - The new way to build your crypto portfolio and use it in daily life. We call it the new money app. https://www.okx.com/
Google Cloud - The next generation of unicorns is building on Google Cloud's industry-leading, fully integrated AI stack: infrastructure, platform, models, agents, and data. https://cloud.google.com/
IREN - IREN AI Cloud, powered by NVIDIA GPUs, provides the scale, performance, and reliability to accelerate your AI journey. https://iren.com/
Oracle - Step into the future of enterprise productivity at Oracle AI Experience Live. https://www.oracle.com/artificial-intelligence/data-ai-events/
Circle - The America-based company behind USDC ? a fully-reserved, enterprise-grade stablecoin at the core of the emerging internet financial system. https://www.circle.com/
BVNK - Building stablecoin-powered financial infrastructure that helps businesses send, store, and spend value instantly, anywhere in the world. https://www.bvnk.com/
Polymarket: https://www.polymarket.com/
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Intro Music Credit:
(0:00) Reacting to Charlie Kirk's death: impact, legacy, and what's wrong in America
(15:27) Assassination culture in America, online radicalization
(30:37) Jimmy Kimmel suspended indefinitely by ABC
(49:11) The Ellison Media Empire: Paramount, Warner Bros Discovery, TikTok
(1:01:09) Besties discover their recent YouTube videos have been flagged as "Restricted"
(1:06:23) All-In Summit recap
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Intro Music Credit:
Intro Video Credit:
Referenced in the show:
https://x.com/charliekirk11/status/1909391943802703899
https://www.bbc.com/news/articles/c99g1e0z2ero
https://networkcontagion.us/reports/4-7-25-ncri-assassination-culture-brief
https://x.com/jk_rowling/status/1966256971134234678
https://x.com/megynkelly/status/1968477822982480298
https://x.com/LizMacDonaldFOX/status/1968837993797665085
https://x.com/bennyjohnson/status/1968359685045838041
https://x.com/TheChiefNerd/status/1968492589201396052
https://latenighter.com/features/analyst-network-late-night-talk-shows-became-unprofitable-in-2023
https://x.com/stoolpresidente/status/1968474692886340002
https://www.wsj.com/tech/details-emerge-on-u-s-china-tiktok-deal-594e009f
https://polymarket.com/event/who-will-acquire-tiktok-559?tid=1758241123068
(0:00) Introducing Solana Co-Founder Anatoly Yakovenko
(0:55) Crypto under Trump vs Biden, stablecoin boom, what it means for US treasuries
(5:56) Traditional exchanges using blockchain vs crypto-native exchanges, how crypto gets mass market
(10:02) Most exciting crypto verticals outside of finance: social, IP rights, real estate, CLARITY Act
(15:57) Quantum computing, AI's impact on crypto
(18:48) Bitcoin: resiliency, market cornering, risks, future
(22:45) Ethereum, Visa/Mastercard
Thanks to our partners for making this happen!
OKX - The new way to build your crypto portfolio and use it in daily life. We call it the new money app. https://www.okx.com/
Google Cloud - The next generation of unicorns is building on Google Cloud's industry-leading, fully integrated AI stack: infrastructure, platform, models, agents, and data. https://cloud.google.com/
IREN - IREN AI Cloud, powered by NVIDIA GPUs, provides the scale, performance, and reliability to accelerate your AI journey. https://iren.com/
Oracle - Step into the future of enterprise productivity at Oracle AI Experience Live. https://www.oracle.com/artificial-intelligence/data-ai-events/
Circle - The America-based company behind USDC ? a fully-reserved, enterprise-grade stablecoin at the core of the emerging internet financial system. https://www.circle.com/
BVNK - Building stablecoin-powered financial infrastructure that helps businesses send, store, and spend value instantly, anywhere in the world. https://www.bvnk.com/
Polymarket: https://www.polymarket.com/
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(0:00) Introducing Uber CEO Dara Khosrowshahi
(0:59) Uber's self-driving business: partnerships, market size, LiDAR vs computer vision, safety, distribution
(8:14) How self-driving impacts Uber's business model over time
(13:30) Other forms of transportation Uber could provide
(16:09) $20B stock buyback plan vs. investing in R&D and acquisitions, future of food
(21:03) Dara's pitch to Elon for bringing Tesla Robotaxis into Uber's network
(22:31) How Uber thinks about driver job displacement from self-driving
Thanks to our partners for making this happen!
Solana - Solana is the high performance network powering internet capital markets, payments, and crypto applications. Connect with investors, crypto founders, and entrepreneurs at Solana's global flagship event during Abu Dhabi Finance Week & F1: https://solana.com/breakpoint
OKX - The new way to build your crypto portfolio and use it in daily life. We call it the new money app. https://www.okx.com/
Google Cloud - The next generation of unicorns is building on Google Cloud's industry-leading, fully integrated AI stack: infrastructure, platform, models, agents, and data. https://cloud.google.com/
IREN - IREN AI Cloud, powered by NVIDIA GPUs, provides the scale, performance, and reliability to accelerate your AI journey. https://iren.com/
Oracle - Step into the future of enterprise productivity at Oracle AI Experience Live. https://www.oracle.com/artificial-intelligence/data-ai-events/
Circle - The America-based company behind USDC ? a fully-reserved, enterprise-grade stablecoin at the core of the emerging internet financial system. https://www.circle.com/
BVNK - Building stablecoin-powered financial infrastructure that helps businesses send, store, and spend value instantly, anywhere in the world. https://www.bvnk.com/
Polymarket: https://www.polymarket.com/
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(0:00) Introducing Dartmouth President Sian Beilock and Berkeley Chancellor Rich Lyons
(1:14) The student loan burden
(8:03) DEI at US universities
(13:56) Administrative bloat
(16:12) Trump vs the Ivy League, viewpoint diversity
(21:56) Impact of K-12 education declining
(25:13) Will AI learning kill higher education?
(29:14) Rising unemployment among recent graduates
(31:35) Role of endowments
Thanks to our partners for making this happen!
Solana - Solana is the high performance network powering internet capital markets, payments, and crypto applications. Connect with investors, crypto founders, and entrepreneurs at Solana's global flagship event during Abu Dhabi Finance Week & F1: solana.com/breakpoint. https://solana.com/
OKX - The new way to build your crypto portfolio and use it in daily life. We call it the new money app. https://www.okx.com/
Google Cloud - The next generation of unicorns is building on Google Cloud's industry-leading, fully integrated AI stack: infrastructure, platform, models, agents, and data. https://cloud.google.com/
IREN - IREN AI Cloud, powered by NVIDIA GPUs, provides the scale, performance, and reliability to accelerate your AI journey. https://iren.com/
Oracle - Step into the future of enterprise productivity at Oracle AI Experience Live. https://www.oracle.com/
Circle - The America-based company behind USDC ? a fully-reserved, enterprise-grade stablecoin at the core of the emerging internet financial system. https://www.circle.com/
BVNK - Building stablecoin-powered financial infrastructure that helps businesses send, store, and spend value instantly, anywhere in the world. https://www.bvnk.com/
Polymarket: https://www.polymarket.com/
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(0:00) Introducing Tulsi Gabbard, US Director of National Intelligence
(1:21) The Russiagate Hoax Conspiracy and the dangers of highly politicized intelligence agencies
(17:31) Russian interference in 2016, cleaning up intelligence agencies, increasing accountability
(25:54) How Tulsi is received in her home state of Hawaii after switching parties, the drastic change of the Democratic Party
(30:16) Thoughts on bombing Iran, what impacts her views on foreign policy and war
(35:15) The impact of designating drug cartels as terrorist orgs, safety at the Southern Border, China
Thanks to our partners for making this happen!
Solana - Solana is the high performance network powering internet capital markets, payments, and crypto applications. Connect with investors, crypto founders, and entrepreneurs at Solana's global flagship event during Abu Dhabi Finance Week & F1: solana.com/breakpoint. https://solana.com/
OKX - The new way to build your crypto portfolio and use it in daily life. We call it the new money app. https://www.okx.com/
Google Cloud - The next generation of unicorns is building on Google Cloud's industry-leading, fully integrated AI stack: infrastructure, platform, models, agents, and data. https://cloud.google.com/
IREN - IREN AI Cloud, powered by NVIDIA GPUs, provides the scale, performance, and reliability to accelerate your AI journey. https://iren.com/
Oracle - Step into the future of enterprise productivity at Oracle AI Experience Live. https://www.oracle.com/
Circle - The America-based company behind USDC ? a fully-reserved, enterprise-grade stablecoin at the core of the emerging internet financial system. https://www.circle.com
BVNK - Building stablecoin-powered financial infrastructure that helps businesses send, store, and spend value instantly, anywhere in the world. https://www.bvnk.com/
Polymarket: https://www.polymarket.com/
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(0:00) Introducing Vlad Tenev
(0:51) Jason tells his story of investing in Robinhood
(3:17) Tokenizing securities, offering tokenized shares in OpenAI and SpaceX, controversy
(7:29) Operating under Trump vs Biden, why offering tokenized securities for private companies could be revolutionary
(17:01) Criticisms around expanding access to sophisticated financial products
(19:34) Current landscape of financial companies, Robinhood's future, competing with incumbents
(23:28) Harmonic and building mathematical superintelligence
Thanks to our partners for making this happen!
Solana - Solana is the high performance network powering internet capital markets, payments, and crypto applications. Connect with investors, crypto founders, and entrepreneurs at Solana's global flagship event during Abu Dhabi Finance Week & F1: solana.com/breakpoint. https://solana.com/
OKX - The new way to build your crypto portfolio and use it in daily life. We call it the new money app. https://www.okx.com/
Google Cloud - The next generation of unicorns is building on Google Cloud's industry-leading, fully integrated AI stack: infrastructure, platform, models, agents, and data. https://cloud.google.com/
IREN - IREN AI Cloud, powered by NVIDIA GPUs, provides the scale, performance, and reliability to accelerate your AI journey. https://iren.com/
Oracle - Step into the future of enterprise productivity at Oracle AI Experience Live. https://www.oracle.com/
Circle - The America-based company behind USDC ? a fully-reserved, enterprise-grade stablecoin at the core of the emerging internet financial system. https://www.circle.com/
BVNK - Building stablecoin-powered financial infrastructure that helps businesses send, store, and spend value instantly, anywhere in the world. https://www.bvnk.com/
Polymarket: https://www.polymarket.com/
Athletic Brewing: https://athleticbrewing.com/
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(0:00) Introducing Sir Demis Hassabis, reflecting on his Nobel Prize win
(2:39) What is Google DeepMind? How does it interact with Google and Alphabet?
(4:01) Genie 3 world model
(9:21) State of robotics models, form factors, and more
(14:42) AI science breakthroughs, measuring AGI
(20:49) Nano-Banana and the future of creative tools, democratization of creativity
(24:44) Isomorphic Labs, probabilistic vs deterministic, scaling compute, a golden age of science
Thanks to our partners for making this happen!
Solana - Solana is the high performance network powering internet capital markets, payments, and crypto applications. Connect with investors, crypto founders, and entrepreneurs at Solana's global flagship event during Abu Dhabi Finance Week & F1: solana.com/breakpoint. https://solana.com/
OKX - The new way to build your crypto portfolio and use it in daily life. We call it the new money app. https://www.okx.com/
Google Cloud - The next generation of unicorns is building on Google Cloud's industry-leading, fully integrated AI stack: infrastructure, platform, models, agents, and data. https://cloud.google.com/
IREN - IREN AI Cloud, powered by NVIDIA GPUs, provides the scale, performance, and reliability to accelerate your AI journey. https://iren.com/
Oracle - Step into the future of enterprise productivity at Oracle AI Experience Live. https://www.oracle.com/
Circle - The America-based company behind USDC ? a fully-reserved, enterprise-grade stablecoin at the core of the emerging internet financial system. https://www.circle.com/
BVNK - Building stablecoin-powered financial infrastructure that helps businesses send, store, and spend value instantly, anywhere in the world. https://www.bvnk.com/
Polymarket: https://www.polymarket.com/
Athletic Brewing: https://athleticbrewing.com/
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(0:00) Introducing Elon Musk, and reflecting on his DOGE experience
(2:47) Optimus: Progress and potential, the "hands problem"
(12:20) Tesla: AI5 chips, impact on FSD
(16:50) SpaceX: Vision for Starlink-enabled smartphones, $17B spectrum deal, Starship update
(26:16) xAI: Next-gen Grok models, Colossus 2, scaling laws, "Grokipedia"
(31:29) Evolving alongside AI, implosion of the West, the religion vacuum
(37:36) Understanding the universe, going to the Moon, what happens on Mars?
Thanks to our partners for making this happen!
Solana - Solana is the high performance network powering internet capital markets, payments, and crypto applications. Connect with investors, crypto founders, and entrepreneurs at Solana's global flagship event during Abu Dhabi Finance Week & F1: solana.com/breakpoint. https://solana.com/
OKX - The new way to build your crypto portfolio and use it in daily life. We call it the new money app. https://www.okx.com/
Google Cloud - The next generation of unicorns is building on Google Cloud's industry-leading, fully integrated AI stack: infrastructure, platform, models, agents, and data. https://cloud.google.com/
IREN - IREN AI Cloud, powered by NVIDIA GPUs, provides the scale, performance, and reliability to accelerate your AI journey. https://iren.com/
Oracle - Step into the future of enterprise productivity at Oracle AI Experience Live. https://www.oracle.com/
Circle - The America-based company behind USDC ? a fully-reserved, enterprise-grade stablecoin at the core of the emerging internet financial system. https://www.circle.com/
BVNK - Building stablecoin-powered financial infrastructure that helps businesses send, store, and spend value instantly, anywhere in the world. https://www.bvnk.com/
Polymarket: https://www.polymarket.com/
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(0:00) Introducing Palantir CEO Alex Karp
(1:10) Understanding Palantir's fans and haters
(8:40) Palantir's work at the border, data collection and surveillance, built-in protections
(20:02) Israel/Palestine
(22:23) Is the West committing suicide?
(30:54) Antisemitism
(31:52) China's strategy, dealing with cartels
(36:46) Why modern Progressivism is not progressive
Thanks to our partners for making this happen!
Solana - Solana is the high performance network powering internet capital markets, payments, and crypto applications. Connect with investors, crypto founders, and entrepreneurs at Solana's global flagship event during Abu Dhabi Finance Week & F1: solana.com/breakpoint. https://solana.com/
OKX - The new way to build your crypto portfolio and use it in daily life. We call it the new money app. https://www.okx.com/
Google Cloud - The next generation of unicorns is building on Google Cloud's industry-leading, fully integrated AI stack: infrastructure, platform, models, agents, and data. https://cloud.google.com/
IREN - IREN AI Cloud, powered by NVIDIA GPUs, provides the scale, performance, and reliability to accelerate your AI journey. https://iren.com/
Oracle - Step into the future of enterprise productivity at Oracle AI Experience Live. https://www.oracle.com/
Circle - The America-based company behind USDC ? a fully-reserved, enterprise-grade stablecoin at the core of the emerging internet financial system. https://www.circle.com/
BVNK - Building stablecoin-powered financial infrastructure that helps businesses send, store, and spend value instantly, anywhere in the world. https://www.bvnk.com/
Polymarket: https://www.polymarket.com/
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(0:00) Introducing Adena Friedman
(1:16) Nasdaq's business, expanding beyond a stock exchange
(2:44) Big announcement! Nasdaq will offer tokenized securities, crypto going mainstream, the 24/5 trading schedule
(7:21) How the IPO market can change to help companies go public faster
(13:37) Evolution of markets: predictions, options, SPVs, secondaries
(18:18) State of the stock market, role at the NY Fed, data issues at the Fed
Thanks to our partners for making this happen!
Solana - Solana is the high performance network powering internet capital markets, payments, and crypto applications. Connect with investors, crypto founders, and entrepreneurs at Solana's global flagship event during Abu Dhabi Finance Week & F1: solana.com/breakpoint. https://solana.com/
OKX - The new way to build your crypto portfolio and use it in daily life. We call it the new money app. https://www.okx.com/
Google Cloud - The next generation of unicorns is building on Google Cloud's industry-leading, fully integrated AI stack: infrastructure, platform, models, agents, and data. https://cloud.google.com/
IREN - IREN AI Cloud, powered by NVIDIA GPUs, provides the scale, performance, and reliability to accelerate your AI journey. https://iren.com/
Oracle - Step into the future of enterprise productivity at Oracle AI Experience Live. https://www.oracle.com/
Circle - The America-based company behind USDC ? a fully-reserved, enterprise-grade stablecoin at the core of the emerging internet financial system. https://www.circle.com/
BVNK - Building stablecoin-powered financial infrastructure that helps businesses send, store, and spend value instantly, anywhere in the world. https://www.bvnk.com/
Polymarket: https://www.polymarket.com/
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(0:00) Introducing Mark Cuban, sadness over Luka Doncic
(2:38) America's broken healthcare system
(15:16) State of the two-party system
(19:24) Introducing Tucker Carlson
(20:01) The fine line between listening and pandering, is Mamdani the Trump of the Left?
(24:27) How to make Americans believe in America again
(34:12) AI job displacement
(39:29) Lightning round with Tucker: Epstein, Putin, why the West is killing itself, the SSRI epidemic, Iryna Zarutska murder
(52:54) Antisemitism and Israel
Thanks to our partners for making this happen!
Solana - Solana is the high performance network powering internet capital markets, payments, and crypto applications. Connect with investors, crypto founders, and entrepreneurs at Solana's global flagship event during Abu Dhabi Finance Week & F1: solana.com/breakpoint. https://solana.com/
OKX - The new way to build your crypto portfolio and use it in daily life. We call it the new money app. https://www.okx.com/
Google Cloud - The next generation of unicorns is building on Google Cloud's industry-leading, fully integrated AI stack: infrastructure, platform, models, agents, and data. https://cloud.google.com/
IREN - IREN AI Cloud, powered by NVIDIA GPUs, provides the scale, performance, and reliability to accelerate your AI journey. https://iren.com/
Oracle - Step into the future of enterprise productivity at Oracle AI Experience Live. https://www.oracle.com/
Circle - The America-based company behind USDC ? a fully-reserved, enterprise-grade stablecoin at the core of the emerging internet financial system. https://www.circle.com/
BVNK - Building stablecoin-powered financial infrastructure that helps businesses send, store, and spend value instantly, anywhere in the world. https://www.bvnk.com/
Polymarket: https://www.polymarket.com/
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(0:00) Introducing Secretary Wright
(1:09) Nuclear, China's approach
(4:02) Increasing energy output, how the climate change complex slowed us down, problems with solar and wind
(11:32) Debating renewables vs nat gas and coal
(18:40) Chamath's energy framework
(21:42) Addressing challenges: budget cuts to research labs, residential energy cost increases due to datacenter demand, speeding up nuclear development
Thanks to our partners for making this happen!
Solana - Solana is the high performance network powering internet capital markets, payments, and crypto applications. Connect with investors, crypto founders, and entrepreneurs at Solana's global flagship event during Abu Dhabi Finance Week & F1: solana.com/breakpoint. https://solana.com/
OKX - The new way to build your crypto portfolio and use it in daily life. We call it the new money app. https://www.okx.com/
Google Cloud - The next generation of unicorns is building on Google Cloud's industry-leading, fully integrated AI stack: infrastructure, platform, models, agents, and data. https://cloud.google.com/
IREN - IREN AI Cloud, powered by NVIDIA GPUs, provides the scale, performance, and reliability to accelerate your AI journey. https://iren.com/
Oracle - Step into the future of enterprise productivity at Oracle AI Experience Live. https://www.oracle.com/
Circle - The America-based company behind USDC ? a fully-reserved, enterprise-grade stablecoin at the core of the emerging internet financial system. https://www.circle.com/
BVNK - Building stablecoin-powered financial infrastructure that helps businesses send, store, and spend value instantly, anywhere in the world. https://www.bvnk.com/
Polymarket: https://www.polymarket.com/
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(0:00) Bestie intros
(0:52) Behind the scenes of the White House Tech Dinner!
(28:39) Tariff showdown headed to the Supreme Court
(42:44) Other Trump Administration legal battles
(46:58) Weak jobs report: what is the state of the economy?
(57:52) Google avoids worst-case scenario in antitrust case
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Referenced in the show:
https://x.com/EdLudlow/status/1963763066988110177
https://www.whitehouse.gov/articles/2025/09/president-trump-tech-leaders-unite-american-ai-dominance
https://www.youtube.com/watch?v=opn9soJ5TYM&t=11s
https://truthsocial.com/@realDonaldTrump/posts/115119151783895076
https://www.congress.gov/bill/94th-congress/house-bill/3884
https://www.cbo.gov/publication/61697
https://x.com/tkl_adam/status/1963961233368924464
https://www.cbsnews.com/news/jobs-report-today-august-2025-three-takeways-federal-reserve
https://www.cnbc.com/2025/09/02/google-antitrust-search-ruling.html
https://polymarket.com/event/us-recession-in-2025?tid=1757216927232
(0:00) David Friedberg welcomes Senator Rand Paul: background, family, what led him to medicine first
(3:56) Career Change: Medicine to Politics
(7:03) Political Philosophy
(10:55) Trade Policy & Economic Impact
(15:52) Consequences of Tariffs
(20:43) Voting Against the One Big Beautiful Bill
(27:52) AI & the Economy
(35:10) Our Fragile Financial System
(41:22) Government Employment & Appropriate Spending
(48:18) COVID Cover Up & Dangers of Gain-of-function Research
(1:01:00) Relations with China
(1:05:52) Political Future
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(0:00) Bestie intros: The Moose is loose at J-Cal Ranch!
(0:46) All-In Summit updates, Jason's new program
(9:45) Trump vs the Federal Reserve: Is the Fed partisan, what should a modern Fed look like?
(36:45) US-Intel Deal: Sustainability, China comparison, could deals like this save Social Security?
(51:37) US Sovereign Wealth Fund
(58:41) Why corporate bankruptcies are trending up in 2025
(1:12:12) OpenAI's novel LLM-based approach to longevity research
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Intro Music Credit:
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Referenced in the show:
https://www.nytimes.com/2025/08/28/us/politics/lisa-cook-trump-fed-lawsuit.html
https://www.housingwire.com/articles/pulte-cook-new-criminal-referral-mortgage-fraud
https://truthsocial.com/@realDonaldTrump/posts/115092130707196133
https://www.cnbc.com/2021/06/10/cpi-may-2021.html
https://www.federalreserve.gov/newsevents/speech/powell20210827a.htm
https://www.npr.org/2021/11/22/1052741845/biden-reappoints-jerome-powell-as-federal-reserve
https://blockworks.co/news/powell-we-can-retire-the-term-transitory-inflation
https://www.statista.com/chart/28437/interest-rate-hikes-in-past-tightening-cycles
https://www.firstlinks.com.au/druckenmiller-biggest-mistake-history-fed
https://www.pbs.org/newshour/economy/u-s-inflation-at-9-1-percent-a-record-high
https://www.reuters.com/markets/us/futures-slip-last-trading-day-torrid-year-2022-12-30
https://truthsocial.com/@realDonaldTrump/posts/114987288040725570
https://x.com/Pavel_Asparagus/status/1960369680457113764
https://openai.com/index/accelerating-life-sciences-research-with-retro-biosciences
(0:00) Bestie intros
(1:59) What's new with the All-In Summit
(9:02) AI Mania hits the brakes: sign of a bubble or a healthy correction?
(30:49) Meta's AI hiring freeze: are the AI talent wars slowing down?
(39:09) Gavin Newsom is the early favorite to be the 2028 Democratic nominee
(54:03) Russia/Ukraine: Trump's two summits, what endgame to expect?
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Intro Music Credit:
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Referenced in the show:
https://x.com/autismcapital/status/1958566758719398351
https://fortune.com/2025/08/18/mit-report-95-percent-generative-ai-pilots-at-companies-failing-cfo
https://www.cnbc.com/2025/08/18/openai-sam-altman-warns-ai-market-is-in-a-bubble.html
https://www.nytimes.com/2025/08/19/technology/mark-zuckerberg-meta-ai.html
https://www.wsj.com/tech/ai/meta-ai-hiring-freeze-fda6b3c4
https://www.cnbc.com/2025/06/19/meta-tried-to-buy-safe-superintelligence-hired-ceo-daniel-gross.html
https://www.nytimes.com/2025/06/12/technology/meta-scale-ai.html
https://polymarket.com/event/democratic-presidential-nominee-2028
https://www.politico.com/f/?id=00000198-c46f-da96-abff-d66f4c1e0000
https://news.gallup.com/poll/693203/ukrainian-support-war-effort-collapses.aspx
(0:00) Sacks and Jason welcome Senator Eric Schmitt
(2:34) Biden v. Missouri, uncovering government censorship as Missouri AG
(6:06) Section 230 and social media, the legacy of Russiagate, big tech censorship in the age of AI
(18:44) Behind the Hunter Biden laptop story and COVID censorship
(30:17) The NGO "Leviathan" and how censorship requests were laundered, Hamilton 68
(36:38) Russiagate and the Obama intel report on the 2016 Election
(47:15) Russia-Ukraine War, possible peace deal, and US foreign policy
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